Research Topics
Species | J M McCuneSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
IFN-alpha secretion by type 2 predendritic cells up-regulates MHC class I in the HIV-1-infected thymusMary E Keir
Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94143, USA
J Immunol 168:325-31. 2002..Furthermore, thymic preDC2 are permissive for HIV-1 infection and positive for intracellular p24. These data demonstrate the ability of IFN-alpha secreted by preDC2 to induce MHC I up-regulation in the HIV-1-infected human thymus...- The dynamics of CD4+ T-cell depletion in HIV diseaseJ M McCune
Gladstone Institute of Virology and Immunology, Departments of Medicine and Microbiology and Immunology, University of California at San Francisco, 94141 9100, USA
Nature 410:974-9. 2001..Ironically, this failure may be precipitated by physiological mechanisms designed to maintain homeostasis in the face of accelerated T-cell loss... 
Factors influencing T-cell turnover in HIV-1-seropositive patientsJ M McCune
The Gladstone Institute of Virology and Immunology, University of California San Francisco, San Francisco, California 94141, USA
J Clin Invest 105:R1-8. 2000..Such interpatient variation in T-cell kinetics may be reflective of differences in functional immune reconstitution after treatment for HIV-1 disease...- Cytomegalovirus (CMV)-specific CD4+ T lymphocyte immune function in long-term survivors of AIDS-related CMV end-organ disease who are receiving potent antiretroviral therapyM A Jacobson
University of California San Francisco, Department of Medicine, Ward 84, 995 Potrero St, San Francisco, CA 94110, USA
J Infect Dis 183:1399-404. 2001..However, 6 of these 10 subjects also had negative CMV-specific immune responses > or =1 time. Such patients may be at risk for future CMV disease progression and should be closely monitored... - High prevalence of thymic tissue in adults with human immunodeficiency virus-1 infectionJ M McCune
The Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, California 94141 9100, USA
J Clin Invest 101:2301-8. 1998..03). These studies suggest that the thymus is functional in some but not all adults with HIV-1 disease... - Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremiaS G Deeks
University of California, San Francisco, and San Francisco General Hospital, USA
N Engl J Med 344:472-80. 2001..In many patients with human immunodeficiency virus (HIV) infection, therapy with potent antiretroviral drugs does not result in complete suppression of HIV replication. The effect of cessation of therapy in these patients is unknown... - Direct measurement of CD4+ and CD8+ T-cell responses to CMV in HIV-1-infected subjectsK V Komanduri
Gladstone Institute of Virology and Immunology, San Francisco, California 94141-9100, USA
Virology 279:459-70. 2001..These declines may precede the onset of CMV-associated end organ disease... - Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasisL A Napolitano
Gladstone Institute of Virology and Immunology, San Francisco General Hospital, and Department of Medicine, University of California at San Francisco, San Francisco, California 94110-9100, USA
Nat Med 7:73-9. 2001..We propose that IL-7 production increases as part of a homeostatic response to T-cell depletion... - Antiviral activity of 2'-deoxy-3'-oxa-4'-thiocytidine (BCH-10652) against lamivudine-resistant human immunodeficiency virus type 1 in SCID-hu Thy/Liv miceC A Stoddart
Antiviral Drug Research Division, Gladstone Institute of Virology and Immunology, San Francisco, California, USA
Antimicrob Agents Chemother 44:783-6. 2000..These experiments demonstrate the utility of this mouse model for evaluating drug resistance and for performing direct comparisons between antiviral compounds in vivo... - Inhibition of human immunodeficiency virus type 1 infection in SCID-hu Thy/Liv mice by the G-quartet-forming oligonucleotide, ISIS 5320C A Stoddart
Gladstone Institute of Virology and Immunology, University of California, San Francisco, California, USA
Antimicrob Agents Chemother 42:2113-5. 1998..Potent in vivo antiviral activity was observed against the T-cell-tropic molecular clone NL4-3; the agent was found to have weak activity against one primary HIV-1 isolate, and the agent was inactive against a second primary isolate... - Impaired replication of protease inhibitor-resistant HIV-1 in human thymusC A Stoddart
Gladstone Institute of Virology and Immunology, University of California at San Francisco, San Francisco, California, USA
Nat Med 7:712-8. 2001..We propose that the inability of PI-resistant HIV-1 to replicate efficiently in thymus contributes to the preservation of CD4+ T-cell counts in patients showing virologic rebound on PI therapy... - Short-term effects of cannabinoids in patients with HIV-1 infection: a randomized, placebo-controlled clinical trialDonald I Abrams
University of California, San Francisco, and Gladstone Institute of Virology and Immunology, San Francisco, California 94110, USA
Ann Intern Med 139:258-66. 2003..CONCLUSIONS: Smoked and oral cannabinoids did not seem to be unsafe in people with HIV infection with respect to HIV RNA levels, CD4+ and CD8+ cell counts, or protease inhibitor levels over a 21-day treatment... - Central memory CD8+ T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progressionKristin Ladell
Division of Experimental Medicine and Department of Medicine, University of California, San Francisco, CA 94110, USA
J Immunol 180:7907-18. 2008.... - Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV diseaseDavid Favre
Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, CA 94110, USA
Sci Transl Med 2:32ra36. 2010..We postulate that induction of IDO may represent a critical initiating event that results in inversion of the T(H)17/T(reg) balance and in the consequent maintenance of a chronic inflammatory state in progressive HIV disease... - HIV-induced changes in T cell signaling pathwaysMarc Schweneker
Division of Experimental Medicine, University of California, San Francisco, CA 94110, USA
J Immunol 180:6490-500. 2008.... - Loss of T cell responses following long-term cryopreservationRachel E Owen
Blood Systems Research Institute, 270 Masonic Avenue, San Francisco, CA 94118, USA
J Immunol Methods 326:93-115. 2007..Long-term cryopreservation, however, may lead to the loss of CD4(+) T cell responses and mild skewing of T cell phenotypic marker expression... - Loss of cytomegalovirus-specific CD4+ T cell responses in human immunodeficiency virus type 1-infected patients with high CD4+ T cell counts and recurrent retinitisK V Komanduri
Gladstone Institute of Virology and Immunology, Department of Medicine, University of California, San Francisco, CA, USA
J Infect Dis 183:1285-9. 2001.... - Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV diseaseDavid M Naeger
Department of Medicine, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 5:e8886. 2010..The impact of untreated and treated HIV infection on the frequency of these cells remains undefined... - Multiparameter evaluation of human thymic function: interpretations and caveatsJeffrey M Harris
Gladstone Institute of Virology and Immunology, University of California at San Francisco, San Francisco, CA 94103, USA
Clin Immunol 115:138-46. 2005..These data illustrate the complex relationship between these measures of thymic size and function and underscore the need to develop more definitive measures of thymic function in the future... - Relationship between T cell activation and CD4+ T cell count in HIV-seropositive individuals with undetectable plasma HIV RNA levels in the absence of therapyPeter W Hunt
Positive Health Program, San Francisco General Hospital, Bldg 80, Ward 84, 995 Potrero Ave, San Francisco, CA 94110, USA
J Infect Dis 197:126-33. 2008.... - Prevalence of CXCR4 tropism among antiretroviral-treated HIV-1-infected patients with detectable viremiaPeter W Hunt
Positive Health Program, San Francisco General Hospital, San Francisco, CA 94110, USA
J Infect Dis 194:926-30. 2006..CCR5 inhibitors may thus be best strategically used before salvage therapy and before significant CD4 + T cell depletion... - Growth hormone enhances thymic function in HIV-1-infected adultsLaura A Napolitano
Gladstone Institute of Virology and Immunology, San Francisco, California 94158, USA
J Clin Invest 118:1085-98. 2008..Further, these randomized, prospective data have shown that thymic involution can be pharmacologically reversed in humans, suggesting that immune-based therapies could be used to enhance thymopoiesis in immunodeficient individuals... - Dehydroepiandrosterone (DHEA) effects on HIV replication and host immunity: a randomized placebo-controlled studyDonald I Abrams
Community Consortium, Positive Health Program, University of California, San Francisco, CA 94143, USA
AIDS Res Hum Retroviruses 23:77-85. 2007.... - Increased carotid intima-media thickness in HIV patients is associated with increased cytomegalovirus-specific T-cell responsesPriscilla Y Hsue
Divisions of Cardiology, San Francisco General Hospital, University of California, San Francisco, USA
AIDS 20:2275-83. 2006.... - Evidence for persistent low-level viremia in individuals who control human immunodeficiency virus in the absence of antiretroviral therapyHiroyu Hatano
San Francisco General Hospital, Building 80, Ward 84, 995 Potrero Avenue, San Francisco, CA 94110, USA
J Virol 83:329-35. 2009..This confirms the failure to eradicate the virus, even in these unique individuals who are able to reduce plasma viremia to very low levels without antiretroviral therapy... - Suberoylanilide hydroxamic acid reactivates HIV from latently infected cellsXavier Contreras
Department of Medicine, University of California, San Francisco, California 94143, USA
J Biol Chem 284:6782-9. 2009..Thus SAHA, which is a Food and Drug Administration-approved drug, might be considered to accelerate the decay of the latent reservoir in HAART-treated infected humans... - Persistent systemic inflammation and atypical enterocolitis in patients with NEMO syndromeLaurence E Cheng
Department of Pediatrics, University of California, San Francisco School of Medicine, San Francisco, CA 94143, USA
Clin Immunol 132:124-31. 2009..Our data suggest that some patients with the NEMO syndrome exhibit persistent elevation of inflammatory markers similar to systemic autoimmune diseases and may subsequently develop an atypical enterocolitis... - IFN-alpha-induced upregulation of CCR5 leads to expanded HIV tropism in vivoCheryl A Stoddart
Division of Experimental Medicine, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, San Francisco, California, USA
PLoS Pathog 6:e1000766. 2010..These observations suggest a mechanism by which IFN-alpha production may paradoxically expand the tropism of R5 HIV and, in so doing, accelerate disease progression... - Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of programmed cell death-1Louise A Swainson
Division of Experimental Medicine, Department of Medicine, University of California at San Francisco, San Francisco, CA 94110, USA
J Immunol 184:3639-47. 2010..These data suggest that FcRL3 expression is associated with T(reg) dysfunction that may, in turn, contribute to the loss of self-tolerance and the development of autoimmunity... - Design, construction, and validation of a modular library of sequence diversity standards for polymerase chain reactionPaul D Baum
University of California, San Francisco, CA 94143, USA
Anal Biochem 411:106-15. 2011..These standards should greatly improve the accuracy and reproducibility of sequence diversity measurements... - HIV-specific CD4+ T cells may contribute to viral persistence in HIV controllersPeter W Hunt
Department of Medicine, University of California, San Francisco, California, USA
Clin Infect Dis 52:681-7. 2011..Despite robust immune responses, these individuals never eradicate HIV infection. We hypothesized that HIV-specific CD4(+) T cells might serve as target cells for HIV, contributing to viral persistence in this setting... - A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllersPeter W Hunt
Departments of Medicine and Laboratory Medicine, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 6:e15924. 2011..These data support a model in which low frequencies of Tregs in HIV controllers may contribute to an effective adaptive immune response, but may also contribute to generalized immune activation, potentially contributing to CD4 depletion... - Neutralizing antibody responses against autologous and heterologous viruses in acute versus chronic human immunodeficiency virus (HIV) infection: evidence for a constraint on the ability of HIV to completely evade neutralizing antibody responsesSteven G Deeks
Department of Medicine, University of California at San Francisco, San Francisco General Hospital, CA 94110, USA
J Virol 80:6155-64. 2006..These observations also suggest that the neutralizing antibody response may contribute to the long-term control of HIV in some patients while protecting against HIV superinfection in most patients... - Increased circulating interleukin-7 levels in HIV-1-infected womenLaura A Napolitano
Gladstone Institute of Virology and Immunology, University of California at San Francisco, 94158, USA
J Acquir Immune Defic Syndr 40:581-4. 2005..0032) after controlling for CD4 count, age, and race. Given the important role of IL-7 in T-cell development and homeostasis, these findings suggest that higher IL-7 levels may contribute to higher CD4 counts in women... - Strong cell-mediated immune responses are associated with the maintenance of low-level viremia in antiretroviral-treated individuals with drug-resistant human immunodeficiency virus type 1Steven G Deeks
Department of Medicine, University of California, San Francisco, San Francisco, California, USA
J Infect Dis 189:312-21. 2004..Collectively, these data suggest that the selection of drug-resistance mutations may reduce the pathogenic potential of HIV, which leads to a balanced state of enhanced cellular immunity and low-level viremia... - Effects of IL-7 on early human thymocyte progenitor cells in vitro and in SCID-hu Thy/Liv miceLaura A Napolitano
Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94141, USA
J Immunol 171:645-54. 2003..Given the growing interest in the use of IL-7 for the treatment of human immunodeficiency, these findings support additional investigation into its in vivo effects on thymopoiesis and HIV infection... - CD4+ T cell kinetics and activation in human immunodeficiency virus-infected patients who remain viremic despite long-term treatment with protease inhibitor-based therapySteven G Deeks
Department of Medicine, University of California at San Francisco and San Francisco General Hospital, San Francisco, CA 94110, USA
J Infect Dis 185:315-23. 2002..These data indicate that partial virus suppression reduces CD4(+) cell turnover and activation, thereby resulting in sustained CD4(+) cell gains, and that measurements of T cell dynamics may provide an in vivo marker of viral virulence... - Enhanced replication of R5 HIV-1 over X4 HIV-1 in CD4(+)CCR5(+)CXCR4(+) T cellsAnn-Marie Roy
Gladstone Institute of Virology and Immunology, 1650 Owens Street, San Francisco, CA 94158, USA
J Acquir Immune Defic Syndr 40:267-75. 2005..This replicative advantage may contribute to the predominance of R5 HIV-1 in vivo... - Comparison of the ELISPOT and cytokine flow cytometry assays for the enumeration of antigen-specific T cellsAnnika C Karlsson
Gladstone Institute of Virology and Immunology, University of California San Francisco, P O Box 419100, San Francisco, CA 94141 9100, USA
J Immunol Methods 283:141-53. 2003..In contrast, the CFC has a greater dynamic range and allows for phenotypic discrimination of responding cells, making it the assay of choice for most other applications... - Growth hormone-induced stimulation of multilineage human hematopoiesisMary B Hanley
Gladstone Institute of Virology and Immunology, 1650 Owens Street, San Francisco, California 94158-2261, USA
Stem Cells 23:1170-9. 2005..These findings identify specific targets of GH and IGF-I within human FBM, and demonstrate direct and indirect effects that may contribute to GH-mediated enhancement of human hemato-lymphopoiesis... - Variations in the heme oxygenase-1 microsatellite polymorphism are associated with plasma CD14 and viral load in HIV-infected African-AmericansL Seu
Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA 94110, USA
Genes Immun 13:258-67. 2012..04). These data demonstrate that the HO-1 GT(n) microsatellite polymorphism is associated with higher levels of HO-1 expression and that this pathway may have important effects on the association between inflammation and HIV replication... - HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus controlBrinda Emu
Positive Health Program, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California, USA
J Virol 82:5398-407. 2008..Defining mechanisms for virus control in "non-T-cell controllers" might lead to insights into preventing HIV transmission or preventing virus replication... - Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progressionKristina Abel
Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
J Exp Med 204:2679-92. 2007..In aggregate, these observations suggest that the T reg cell compartment of the infant macaque facilitates rapid disease progression, at least in part by incapacitating SIV-specific CD4(+) T cell responses... - Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cellsDENNIS J HARTIGAN-O'CONNOR
Division of Experimental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
J Immunol Methods 319:41-52. 2007..This surface phenotype should allow for quantitative studies of regulatory T cells in disease states as well as for enrichment of live regulatory T cells for functional analyses and/or expansion in vitro... - Naive human T cells are activated and proliferate in response to the heme oxygenase-1 inhibitor tin mesoporphyrinTrevor D Burt
Division of Neonatology, Department of Pediatrics, University of California San Francisco, San Francisco, CA 94110, USA
J Immunol 185:5279-88. 2010..Based on these findings, we propose a potential role for HO-1 in the control of naive T cell homeostatic proliferation... - Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormoneLaura A Napolitano
Gladstone Institute of Virology and Immunology, University of California at San Francisco, San Francisco, CA 94141, USA
AIDS 16:1103-11. 2002..CONCLUSION: GH has significant effects on the human immune system, including the reversal of thymic atrophy in HIV-1-infected adults. De-novo T cell production may thus be inducible in immunodeficient adults... - A membrane-bound Fas decoy receptor expressed by human thymocytesM Jenkins
Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141 9100, USA
J Biol Chem 275:7988-93. 2000.... - Gene expression profiles during human CD4+ T cell differentiationMyeong Sup Lee
Gladstone Institute of Virology and Immunology, University of California at San Francisco, San Francisco, CA 94141, USA
Int Immunol 16:1109-24. 2004..Further evaluation of these findings may lead to a better definition of human thymopoiesis as well as to improved approaches to monitor and to augment the function of this important organ of T cell production... - Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in uteroJeff E Mold
Division of Experimental Medicine, Department of Medicine, University of California at San Francisco UCSF, San Francisco, CA 94110, USA
Science 322:1562-5. 2008..These findings reveal a form of antigen-specific tolerance in humans, induced in utero and probably active in regulating immune responses after birth... - Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE epsilon4/epsilon4 genotype accelerates HIV disease progressionTrevor D Burt
Division of Experimental Medicine, Department of Medicine, and Division of Neonatology, Department of Pediatrics, University of California, San Francisco, CA 94110, USA
Proc Natl Acad Sci U S A 105:8718-23. 2008.... - HIV-infected liver and kidney transplant recipients: 1- and 3-year outcomesM E Roland
University of California, San Francisco, CA, USA
Am J Transplant 8:355-65. 2008.... - Th17 and regulatory T cells: implications for AIDS pathogenesisBittoo Kanwar
Division of Experimental Medicine, Department of Medicine, University of California San Francisco, CA 94110, USA
Curr Opin HIV AIDS 5:151-7. 2010.... - Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesisCheryl A Stoddart
Gladstone Institute of Virology and Immunology Departments of Medicine Microbiology and Immunology, University of California, San Francisco, California 94141, USA
J Virol 77:2124-33. 2003..Nef-mediated CD4 downregulation merits consideration as a new target for the development of small-molecule inhibitors... - The role of transplacental microtransfusions of maternal lymphocytes in in utero HIV transmissionTzong Hae Lee
Blood Systems Research Institute, San Francisco, CA, USA
J Acquir Immune Defic Syndr 55:143-7. 2010..The mechanisms of HIV transmission from mothers to infants are poorly understood. A possible mechanism of in utero transmission is transplacental transfer of HIV-infected maternal leukocytes into the fetal circulation during pregnancy... - In vivo imaging of mucosal CD4+ T cells using single photon emission computed tomography in a murine model of colitisBittoo Kanwar
Department of Medicine, Division of Experimental Medicine, The University of California, San Francisco, San Francisco, CA 94143 1234, USA
J Immunol Methods 329:21-30. 2008..This approach should be readily applicable to the imaging of discrete cell subpopulations in non-human primates and in humans, thus augmenting our understanding of infectious diseases and inflammation in vivo... - Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentationKristy Red-Horse
Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, California, USA
J Clin Invest 116:2643-52. 2006.... - HIV tropism and CD4+ T-cell depletionMark B Feinberg
Nat Med 8:537. 2002 - Generation of CD3+CD8low thymocytes in the HIV type 1-infected thymusMary E Keir
Biomedical Sciences Graduate Program, University of California, San Francisco 94143, USA
J Immunol 169:2788-96. 2002..We suggest that this HIV-1-initiated selection process may contribute to the generation of dysfunctional CD8(+) T cells in HIV-1-infected patients... - Short-term effects of cannabinoids on immune phenotype and function in HIV-1-infected patientsBarry M Bredt
Department of Medicine, General Clinical Research Center at San Francisco General Hospital, CA 94110, USA
J Clin Pharmacol 42:82S-89S. 2002..On the basis of these measurements and during this short 21-day study period, few statistically significant effects were noted on immune system phenotypes orfunctions in this patient population... - Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infectionMarc K Hellerstein
University of California, Berkeley, 119 Morgan Hall, Berkeley, California 94720 3104, USA
J Clin Invest 112:956-66. 2003..The greatest impact of advanced HIV-1 infection is to reduce the generation of long-lived, potential progenitor T cells... - HIV-1-specific CD4+ T cell responses in chronically HIV-1 infected blippers on antiretroviral therapy in relation to viral replication following treatment interruptionEmmanouil Papasavvas
The Wistar Institute, Philadelphia, Pennsylvania 19104, USA
J Clin Immunol 26:40-54. 2006..04) with no difference between groups by week 24. These data support that blippers have higher anti-HIV lymphoproliferative responses while on ART but experience equal to higher viral rebound as compared to matched non-blippers upon TI... - Isolation of peripheral blood CD4(+) T cells using RosetteSep and MACS for studies of DNA turnover by deuterium labelingRobert Busch
KineMed, Inc, 5980 Horton St, Emeryville, CA 94608, USA
J Immunol Methods 286:97-109. 2004..Thus, both FACS and the new method isolate a similar mixture of long- and short-lived CD4(+) T cells. In practice, the RosetteSep/MACS method is simple, rapid, robust and capable of high throughput... - Effect of SIVmac infection on plasmacytoid and CD1c+ myeloid dendritic cells in cynomolgus macaquesBenoit Malleret
CEA, Service d Immuno Virologie, DSV iMETI, IPSC, Fontenay aux Roses, France
Immunology 124:223-33. 2008..Information regarding absolute pDC and mDC counts in non-human primates may improve our understanding of the role of these cells in SIV/HIV infection and in other infectious diseases... - Long-term changes in circulating CD4 T lymphocytes in virologically suppressed patients after 6 years of highly active antiretroviral therapyKimberly Smith
Department of Infectious Diseases, Rush Medical College of Rush University, Chicago, IL 60612, USA
AIDS 18:1953-6. 2004..This cohort represents the longest prospective immunological follow-up of virologically suppressed patients on HAART... - Antiviral antibodies are necessary for control of simian immunodeficiency virus replicationChristopher J Miller
Center for Comparative Medicine, California National Primate Research Center, University of California, Davis, Davis, California 95616, USA
J Virol 81:5024-35. 2007..0001). These observations indicate that antiviral antibody responses are critical in maintaining effective control of SIV replication at early time points postinfection... - Phenotypic, functional, and kinetic parameters associated with apparent T-cell control of human immunodeficiency virus replication in individuals with and without antiretroviral treatmentBrinda Emu
Department of Medicine, San Francisco General Hospital, University of California, 94110, USA
J Virol 79:14169-78. 2005.... - A plea for justice for jailed medical workersSunil K Ahuja
Science 314:924-5. 2006 - Public health. A sound rationale needed for phase III HIV-1 vaccine trialsDennis R Burton
Scripps Research Institute, La Jolla, California, USA
Science 303:316. 2004