Jeffrey McCullough

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi request reprint Clinical safety of platelets photochemically treated with amotosalen HCl and ultraviolet A light for pathogen inactivation: the SPRINT trial
    Edward Snyder
    Yale University Medical School, Yale New Haven Hospital, New Haven, Connecticut, USA
    Transfusion 45:1864-75. 2005
  2. ncbi request reprint The role of physicians in blood centers
    Jeffrey McCullough
    Department of Laboratory Medicine and Pathology, Biomedical Engineering Institute, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Transfusion 46:854-61. 2006
  3. ncbi request reprint The National Marrow Donor Program with emphasis on the early years
    Jeffrey McCullough
    University of Minnesota, Minneapolis, Minnesota 55455, USA
    Transfusion 46:1248-55. 2006
  4. ncbi request reprint Issues in the quality of umbilical cord blood stem cells for transplantation
    Jeffrey McCullough
    Clinical Cell Therapy Laboratory and the Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Transfusion 45:832-41. 2005
  5. doi request reprint Career activities of physicians taking the subspecialty board examination in blood banking/transfusion medicine
    Jeffrey McCullough
    Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota, USA
    Transfusion 48:762-7. 2008
  6. pmc Mislabeled units of umbilical cord blood detected by a quality assurance program at the transplantation center
    Jeffrey McCullough
    Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA
    Blood 114:1684-8. 2009
  7. ncbi request reprint White particulate matter: report of the ad hoc industry review group
    Jeffrey McCullough
    University of Minnesota, Minneapolis, Minnesota, USA
    Transfusion 44:1112-8. 2004
  8. doi request reprint Long-term storage of peripheral blood stem cells frozen and stored with a conventional liquid nitrogen technique compared with cells frozen and stored in a mechanical freezer
    Jeffrey McCullough
    Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA
    Transfusion 50:808-19. 2010
  9. ncbi request reprint Therapeutic efficacy and safety of platelets treated with a photochemical process for pathogen inactivation: the SPRINT Trial
    Jeffrey McCullough
    University of Minnesota, MMC 609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Blood 104:1534-41. 2004
  10. doi request reprint Overview of platelet transfusion
    Jeffrey McCullough
    Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA
    Semin Hematol 47:235-42. 2010

Research Grants

  1. RESEARCH TRAINING IN TRANSFUSION MEDICINE
    Jeffrey McCullough; Fiscal Year: 2003
  2. Clinical Trials in Transfusion Medicine and Hemostasis
    Jeffrey McCullough; Fiscal Year: 2007

Detail Information

Publications42

  1. ncbi request reprint Clinical safety of platelets photochemically treated with amotosalen HCl and ultraviolet A light for pathogen inactivation: the SPRINT trial
    Edward Snyder
    Yale University Medical School, Yale New Haven Hospital, New Haven, Connecticut, USA
    Transfusion 45:1864-75. 2005
    ..Hemostatic equivalency was demonstrated. The proportion of patients with Grade 2 bleeding was not inferior for PCT PLTs...
  2. ncbi request reprint The role of physicians in blood centers
    Jeffrey McCullough
    Department of Laboratory Medicine and Pathology, Biomedical Engineering Institute, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Transfusion 46:854-61. 2006
  3. ncbi request reprint The National Marrow Donor Program with emphasis on the early years
    Jeffrey McCullough
    University of Minnesota, Minneapolis, Minnesota 55455, USA
    Transfusion 46:1248-55. 2006
  4. ncbi request reprint Issues in the quality of umbilical cord blood stem cells for transplantation
    Jeffrey McCullough
    Clinical Cell Therapy Laboratory and the Blood and Marrow Transplant Program, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Transfusion 45:832-41. 2005
    ..Because the frequency of umbilical cord blood (UCB) stem cell transplantation has increased, the quality of UCB available in banks is an important part of the success of UCB stem cell transplants...
  5. doi request reprint Career activities of physicians taking the subspecialty board examination in blood banking/transfusion medicine
    Jeffrey McCullough
    Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota, USA
    Transfusion 48:762-7. 2008
    ..Changes in blood banking and transfusion medicine (BB/TM) in the past 15 years may have made BB/TM a less attractive career choice than previously for physicians...
  6. pmc Mislabeled units of umbilical cord blood detected by a quality assurance program at the transplantation center
    Jeffrey McCullough
    Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA
    Blood 114:1684-8. 2009
    ..2%) cord blood units sent to us for transplantation were mislabeled and potentially would have been transplanted incorrectly. This error rate of 1 per 249 (0.4%) patients could have potentially devastating consequences...
  7. ncbi request reprint White particulate matter: report of the ad hoc industry review group
    Jeffrey McCullough
    University of Minnesota, Minneapolis, Minnesota, USA
    Transfusion 44:1112-8. 2004
    ..An expert panel was formed to evaluate studies of the material and make appropriate recommendations..
  8. doi request reprint Long-term storage of peripheral blood stem cells frozen and stored with a conventional liquid nitrogen technique compared with cells frozen and stored in a mechanical freezer
    Jeffrey McCullough
    Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA
    Transfusion 50:808-19. 2010
    ..We compared the liquid nitrogen method with methods using a combination of dimethyl sulfoxide (DMSO) and hydroxyethyl starch (HES) for cryopreservation followed by storage in mechanical freezers...
  9. ncbi request reprint Therapeutic efficacy and safety of platelets treated with a photochemical process for pathogen inactivation: the SPRINT Trial
    Jeffrey McCullough
    University of Minnesota, MMC 609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Blood 104:1534-41. 2004
    ..02). The incidence of grade 2 bleeding was equivalent for PCT and conventional platelets, although posttransfusion platelet count increments and days to next transfusion were decreased for PCT compared with conventional platelets...
  10. doi request reprint Overview of platelet transfusion
    Jeffrey McCullough
    Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA
    Semin Hematol 47:235-42. 2010
    ..Transfusion is helpful to treat nonsurgical serious bleeding. In idiopathic thrombocytopenic purpura, platelet survival is short and transfusion is useful only for severe bleeding...
  11. ncbi request reprint Transfusion medicine: discipline with a future
    Jeffrey McCullough
    Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Transfusion 43:823-8. 2003
  12. ncbi request reprint Cell loss and recovery in umbilical cord blood processing: a comparison of postthaw and postwash samples
    Vincent Laroche
    Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Transfusion 45:1909-16. 2005
    ..This study examines the effect of the wash step as well as that of PT storage on various quality control variables of UCB units...
  13. ncbi request reprint Impact of donor- and collection-related variables on product quality in ex utero cord blood banking
    Sabeen Askari
    Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota 55417, USA
    Transfusion 45:189-94. 2005
    ..Optimizing product quality is a current focus in cord blood banking. This study evaluates the role of selected donor- and collection-related variables...
  14. ncbi request reprint Pathogen inactivation of platelets with a photochemical treatment with amotosalen HCl and ultraviolet light: process used in the SPRINT trial
    Alvaro Pineda
    Mayo Clinic, Rochester, Minnesota, USA
    Transfusion 46:562-71. 2006
    ..The system comprises PLT additive solution (PAS III), amotosalen HCl, a compound adsorption device (CAD), a microprocessor-controlled ultraviolet A light source, and a commercially assembled system of interconnected plastic containers...
  15. doi request reprint Successful "in-flight" activation of natural killer cells during long-distance shipping
    Scott A Koepsell
    Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, University of Minnesota Medical School, St Paul, USA
    Transfusion 53:398-403. 2013
    ..Here we describe the qualification of in transit activation of an NK-cell therapy product in preparation for a Phase I clinical trial at a distant medical center...
  16. ncbi request reprint Microbial contamination of hematopoietic stem cell products: incidence and clinical sequelae
    Mark A Klein
    Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA
    Biol Blood Marrow Transplant 12:1142-9. 2006
    ..Prophylactic antibiotics are useful for certain contaminants; however, caution must be exercised when gram-negative contaminated products are administered...
  17. ncbi request reprint Patient care during infusion of hematopoietic progenitor cells
    Annette Sauer-Heilborn
    Division of Transfusion Medicine, Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
    Transfusion 44:907-16. 2004
  18. ncbi request reprint The role of the paternal health history in cord blood banking
    Sabeen Askari
    Cord Blood Program, American Red Cross North Central Blood Services, St Paul, Minnesota, USA
    Transfusion 42:1275-8. 2002
    ..Whereas most UCB banks do not require paternal consent or paternal health history (PHH), both are obtained at this institution whenever possible. This study assessed the value of PHH in making UCB safer...
  19. ncbi request reprint Short-term liquid storage of umbilical cord blood
    Allison Hubel
    Department of Mechanical Engineering, University of Minnesota, 1100 Mechanical Engineering, 111 Church Steet SE, Minneapolis, MN 55455, USA
    Transfusion 43:626-32. 2003
    ..Processing and banking of umbilical cord blood requires the development of methods for short-term liquid storage. This study examines the conditions (temperature, time, and storage solution) for optimal storage of cord blood...
  20. doi request reprint Status of blood banking and the blood supply in Afghanistan
    M Tayyeb Ayyoubi
    Department of Laboratory Medicine and Pathology, Institute for Engineering in Medicine, Medical School, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Transfusion 50:566-74. 2010
    ..We carried out an assessment of that blood supply system to determine the type and extent of assistance needed to increase blood availability and safety...
  21. ncbi request reprint Using lean techniques to define the platelet (PLT) transfusion process and cost-effectiveness to evaluate PLT dose transfusion strategies
    William Riley
    Department of Health Policy and Management, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Transfusion 52:1957-67. 2012
    ..4 × 10(11) /m(2) body surface area are equally effective in preventing bleeding. These different dose strategies involve different numbers of transfusions. We conducted a cost analysis of three separate PLT dose therapies...
  22. ncbi request reprint Pathogen inactivation: a new paradigm for preventing transfusion-transmitted infections
    Jeffrey McCullough
    Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA
    Am J Clin Pathol 128:945-55. 2007
    ..The shortcomings of our present paradigm for preventing transfusion-transmitted diseases are described, along with a summary of the status of pathogen inactivation...
  23. ncbi request reprint Platelet utilization and the transfusion trigger: a prospective analysis
    Edward Greeno
    Department of Medicine and Laboratory Medicine, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Transfusion 47:201-5. 2007
    ..Prophylactic platelet (PLT) transfusion practices have become more conservative as studies support a threshold for transfusions at 10 x 10(9) per L. This change in practice may reduce our use of PLT transfusions...
  24. doi request reprint The influence of bleeding on trigger changes for platelet transfusion in patients with chemotherapy-induced thrombocytopenia
    Benjamin Rioux-Massé
    Department of Laboratory Medicine and Pathology, Masonic Cancer Center, Institute for Engineering in Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, USA
    Transfusion 53:306-14. 2013
    ..For patients with thrombocytopenia without bleeding risk factors, a platelet transfusion trigger of 10 × 10(9) /L is recommended. No studies have evaluated the clinicians' decision-making process leading to trigger changes...
  25. ncbi request reprint Good manufacturing practices production of natural killer cells for immunotherapy: a six-year single-institution experience
    David H McKenna
    Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, University of Minnesota Medical School, Minnesota 55108, USA
    Transfusion 47:520-8. 2007
    ..Herein is a report on the experience of clinical-scale, good manufacturing practices (GMPs) production of NK cells to treat advanced cancer...
  26. ncbi request reprint Progress toward a pathogen-free blood supply
    Jeffrey McCullough
    Department of Laboratory Medicine and Pathology and Biomedical Engineering Institute, University of Minnesota, Minneapolis, MN 55455, USA
    Clin Infect Dis 37:88-95. 2003
    ..If these encouraging results are sustained, the risk of transfusion-transmitted disease may be nearly eliminated...
  27. doi request reprint Meaningful use of health information technology by rural hospitals
    Jeffrey McCullough
    Division of Health Policy and Management, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Rural Health 27:329-37. 2011
    ....
  28. ncbi request reprint A phased consent policy for cord blood donation
    Dorothy E Vawter
    Minnesota Center for Health Care Ethics, 601 25th Avenue South, Minneapolis, MN 55454, USA
    Transfusion 42:1268-74. 2002
    ....
  29. ncbi request reprint The Minnesota Molecular and Cellular Therapeutics Facility: a state-of-the-art biotherapeutics engineering laboratory
    David H McKenna
    Division of Minnesota Molecular and Cellular Therapeutics Facility, University of Minnesota, Saint Paul, MN 55108, USA
    Transfus Med Rev 19:217-28. 2005
    ..Here we provide an overview of the Minnesota Molecular and Cellular Therapeutics (MMCT) Facility, detailing our approach to the manufacture of novel therapeutics and highlighting current and future activities...
  30. doi request reprint Effects of granulocyte-colony stimulating factor on chromosome aneuploidy and replication asynchrony in healthy peripheral blood stem cell donors
    Betsy Hirsch
    Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN, USA
    Blood 118:2602-8. 2011
    ..No evidence was found of G-CSF-induced chromosomal instability. This work supports the epidemiologic data that have demonstrated no increased risk for hematologic malignancies in G-CSF-primed PBSC donors...
  31. pmc The cost-effectiveness of platelet additive solution to prevent allergic transfusion reactions
    Seema Kacker
    Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland Department of Pathology, Johns Hopkins University, Baltimore, Maryland Department of Pathology, Brigham and Women s Hospital, Boston, Massachusetts Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota
    Transfusion 53:2609-18. 2013
    ..Storage in platelet additive solution (PAS) has been shown to reduce ATRs from apheresis platelets (APs). This study evaluated the cost-effectiveness of using PAS storage as an alternative method to reduce ATRs...
  32. ncbi request reprint Stored platelets contain residual amounts of tissue factor: evidence from studies on platelet concentrates stored for prolonged periods
    Silvia Perez-Pujol
    Department of Medicine and Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA
    Transfusion 45:572-9. 2005
    ..The advent of new strategies for pathogen reduction has raised the question of whether platelet (PLT) concentrates (PCs) exposed to longer periods of storage retain adequate hemostatic function...
  33. ncbi request reprint Consensus conference on vCJD screening of blood donors: report of the panel
    Jeffrey McCullough
    University of Minnesota, Minneapolis, Minnesota 55455, USA
    Transfusion 44:675-83. 2004
  34. doi request reprint Recommendations for nanomedicine human subjects research oversight: an evolutionary approach for an emerging field
    Leili Fatehi
    University of Minnesota, MN, USA
    J Law Med Ethics 40:716-50. 2012
    ....
  35. ncbi request reprint The United States' potential blood donor pool: estimating the prevalence of donor-exclusion factors on the pool of potential donors
    William Riley
    School of Public Health, Laboratory Medicine and Pathology, The University of Minnesota, Minneapolis, Minnesota 55455, USA
    Transfusion 47:1180-8. 2007
    ..An epidemiologic model has been developed to determine the prevalence of donor exclusions and thus improve the estimate of total eligible blood donors in the nation...
  36. ncbi request reprint Platelet dose consistency and its effect on the number of platelet transfusions for support of thrombocytopenia: an analysis of the SPRINT trial of platelets photochemically treated with amotosalen HCl and ultraviolet A light
    Scott Murphy
    American Red Cross Blood Services, Philadelphia, Pennsylvania, USA
    Transfusion 46:24-33. 2006
    ..PLT dose was analyzed to determine the impact of the number of PLTs transfused on transfusion requirements...
  37. ncbi request reprint Non-frozen preservation of umbilical cord blood
    Ulrike F Koenigbauer
    Transfusion 42:1383-4. 2002
  38. ncbi request reprint Pathogen inactivation: a new paradigm for blood safety
    Jeffrey McCullough
    Transfusion 47:2180-4. 2007
  39. pmc Factors affecting posttransfusion platelet increments, platelet refractoriness, and platelet transfusion intervals in thrombocytopenic patients
    Sherrill J Slichter
    Puget Sound Blood Center, Seattle, WA 98104 1256, USA
    Blood 105:4106-14. 2005
    ..The only factors that reduced platelet refractoriness rates were increasing the dose of platelets transfused or transfusing filtered apheresis platelets...
  40. ncbi request reprint Blood collection and transfusion in the United States in 1997
    Marian T Sullivan
    National Blood Data Resource Center, 8101 Glenbrook Road, Bethesda, MD 20814, USA
    Transfusion 42:1253-60. 2002
    ..Collections, processing, and transfusions of blood and blood components in the US in 1997 were measured and compared with 1994 and prior years...
  41. ncbi request reprint Relationship between tick bites and the seroprevalence of Babesia microti and Anaplasma phagocytophila (previously Ehrlichia sp.) in blood donors
    David A Leiby
    Transmissible Diseases Department, American Red Cross, Rockville, MD 20855, USA
    Transfusion 42:1585-91. 2002
    ..Despite an increased recognition of the threat tick-borne agents pose to blood safety, our understanding of the prevalence and transmissibility of these agents in blood donors is limited...
  42. ncbi request reprint Therapeutic efficacy and safety of red blood cells treated with a chemical process (S-303) for pathogen inactivation: a Phase III clinical trial in cardiac surgery patients
    Richard J Benjamin
    Joint Program in Transfusion Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Transfusion 45:1739-49. 2005
    ..A randomized, double-blind trial is reported of the clinical efficacy of red blood cells (RBCs) treated for pathogen inactivation with S-303, a synthetic labile alkylating agent...

Research Grants3

  1. RESEARCH TRAINING IN TRANSFUSION MEDICINE
    Jeffrey McCullough; Fiscal Year: 2003
    ..abstract_text> ..
  2. Clinical Trials in Transfusion Medicine and Hemostasis
    Jeffrey McCullough; Fiscal Year: 2007
    ..Disseminate results of the TMH CTN through presentation and publication of clinical trial results and other TMH CTN activities. UNIVERSITY OF MINNESOTA CRITIQUES ..