Research Topics
| J S McCombsSummaryAffiliation: University of Southern California Country: USA Publications
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Detail Information
Publications
The use of conventional antipsychotic medications for patients with schizophrenia in a medicaid population: therapeutic and cost outcomes over 2 yearsJ S McCombs
Department of Pharmaceutical Economics and Policy, School of Pharmacy, University of Southern California, Los Angeles, CA, USA
Value Health 3:222-31. 2000..To evaluate the association between drug therapy patterns achieved with conventional antipsychotics and direct healthcare costs over 2 years...
Access to drug therapy and substitution between alternative antidepressants following an expansion of the California Medicaid formularyJeffrey S McCombs
Department of Pharmaceutical Economics and Policy, USC School of Pharmacy, University of Southern California, 1540 E Alcazar St, Rm CHP 140, Los Angeles, CA 90033, USA
Health Policy 65:301-11. 2003..However, while some expansion in overall antidepressant use may have been desired, the clinical validity of this expansion cannot be determined based on the results presented here...
Use patterns for antipsychotic medications in medicaid patients with schizophreniaJ S McCombs
Department of Pharmaceutical Economics and Policy, School of Pharmacy, University of Southern California, Los Angeles 90033, USA
J Clin Psychiatry 60:5-11; discussion 12-3. 1999..We investigated the use patterns for antipsychotic medications generated by Medicaid patients with schizophrenia...
A retrospective analysis of the revocation of prior authorization restrictions and the use of antidepressant medications for treating major depressive disorderJeffrey S McCombs
Department of Pharmaceutical Economics and Policy, School of Pharmacy, University of Southern California, Los Angeles, CA 90033, USA
Clin Ther 24:1939-59; discussion 1938. 2002..The California Medicaid (Medi-Cal) program removed prior authorization restrictions for 2 selective serotonin reuptake inhibitors (SSRIs), fluoxetine and paroxetine, in May 1996...
Antipsychotic drug use patterns and the cost of treating schizophreniaJ S McCombs
Department of Pharmaceutical Economics and Policy, Univeristy of Southern California, 1540 East Alcazar Street, Los Angeles, USA
Psychiatr Serv 51:525-7. 2000..Completing one year of uninterrupted drug therapy was correlated with higher nursing home costs. Delayed drug treatment and changes in therapy increased the cost by $9,418 and $9,719, respectively...
Use of conventional antipsychotics and the cost of treating schizophreniaR R Lyu
School of Pharmacy, University of Southern California, USA
Health Care Financ Rev 23:83-99. 2001..0001); 41 percent of treated patients changed therapy with similar results (+$4,067, p < .0001). Only 20 percent of patients were compliant with drug therapy but this had no significant impact on total treatment costs...
Cost of treating bipolar disorder in the California Medicaid (Medi-Cal) programJinmei Li
Department of Pharmaceutical Economics and Policy, University of Southern California School of Pharmacy, 1540 E. Alcazar St, Rm. CHP-140, Los Angeles, CA 90033, USA
J Affect Disord 71:131-9. 2002..CONCLUSIONS: Suboptimal use patterns for mood stabilizing medications were frequent and costly. Strategies to improve compliance with mood stabilizer regimens, along with new treatment options, are needed to improve treatment outcomes...
The impact of atypical antipsychotic medications on the use of health care by patients with schizophreniaLei Chen
Department of Pharmaceutical Economics and Policy, School of Pharmacy, University of Southern California, Los Angeles, CA, USA
Value Health 11:34-43. 2008..Using data in real-world clinical practice, this study aims to compare the health-care use patterns of patients with schizophrenia who use oral antipsychotics...
The impact of unrecognized bipolar disorders among patients treated for depression with antidepressants in the fee-for-services California Medicaid (Medi-Cal) program: a 6-year retrospective analysisJeffrey S McCombs
Department of Pharmaceutical Economics and Policy, School of Pharmacy, University of Southern California, Los Angeles, CA 90089 9004, USA
J Affect Disord 97:171-9. 2007..The cost of unrecognized bipolar disorders over time is unknown...
Classifying patients by antipsychotic adherence patterns using latent class analysis: characteristics of nonadherent groups in the California Medicaid (Medi-Cal) programJeonghoon Ahn
University of Southern California, Los Angeles, CA, USA
Value Health 11:48-56. 2008..This study identifies latent classes defined by varying degrees of adherence to antipsychotic drug therapy and examines the sociodemographic, clinical, and resource utilization correlates associated with membership in each adherence class...
A1C and cardiovascular outcomes in type 2 diabetes: a nested case-control studyDanielle C Colayco
University of Southern California School of Pharmacy, Department of Pharmaceutical Economics and Policy, Los Angeles, California, USA
Diabetes Care 34:77-83. 2011..The role of aggressive glycemic control in preventing cardiovascular events is unclear. A nested case-control study design was used to evaluate the association between average A1C and cardiovascular outcomes...
Open access to innovative drugs: treatment substitutions or treatment expansion?Jeffrey S McCombs
Department of Pharmaceutical Economics and Policy School of Pharmacy, University of Southern California, USA
Health Care Financ Rev 25:35-53. 2004..Program administrators must use caution when evaluating the impact of unrestricted access on drug therapy outcomes and treatment costs given the changes in the characteristics of patients seeking treatment...
Compliance with drug therapies for the treatment and prevention of osteoporosisJeffrey S McCombs
Department of Pharmaceutical Economics and Policy, School of Pharmacy, University of Southern California, Los Angeles, CA, USA
Maturitas 48:271-87. 2004..This study used paid claims data from real-world treatment settings to investigate the impact of hormone replacement therapy (HRT), bisphosphonate and raloxifene on patients with a recorded diagnosis of osteoporosis...
Medication use in residential care facilities for the elderlyB R Williams
Clinical Pharmacy and Clinical Gerontology, School of Pharmacy, University of Southern California, and Ethel Percy Andrus Gerontology Center, Los Angeles 90033, USA
Ann Pharmacother 33:149-55. 1999..To describe medication use by residents of residential care facilities for the elderly (RCFEs)...
Duration of antipsychotic drug therapy in real-world practice: a comparison with CATIE trial resultsLei Chen
Department of Pharmaceutical Economics and Policy, School of Pharmacy, University of Southern California, Los Angeles, CA, USA
Value Health 11:487-96. 2008..This study compares the TTAD achieved when using alternative antipsychotics to treat patients with schizophrenia in real-world practice settings...
Pharmacoeconomics: what is it and where is it going?J S McCombs
University of Southern California School of Pharmacy, Pharmaceutical Economics and Policy, Los Angeles 90033, USA
Am J Hypertens 11:112S-119S; discussion 135S-137S. 1998....
The impact of unrecognized bipolar disorders for patients treated for depression with antidepressants in the fee-for-services California Medicaid (Medi-Cal) programLizheng Shi
Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA
J Affect Disord 82:373-83. 2004..More effort is needed to provide early and correct diagnosis and effectively treat both recognized-BP and unrecognized-BP patients...
Effects of ambulatory-care pharmacist consultation on mortality and hospitalizationYong Yuan
Global Epidemiology Outcomes Research, Bristol-Myers Squibb, Princeton, NJ, USA
Am J Manag Care 9:45-56. 2003..Broader nontargeted consultation would reduce hospitalizations, but was not associated with lower mortality within the 2-year intervention...
Defining and measuring clinical effectiveness in the treatment of schizophreniaHenry A Nasrallah
Department of Psychiatry, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0559, USA
Psychiatr Serv 56:273-82. 2005..This report describes an approach to define and measure the clinical effectiveness of treatment in achieving these objectives...
Can pharmacy data improve prediction of hospital outcomes? Comparisons with a diagnosis-based comorbidity measureJoseph P Parker
Health Care Quality and Analysis Division, California Office of Statewide Health Planning and Development, Sacramento 95814, USA
Med Care 41:407-19. 2003....
