Anthony L McCall

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. ncbi request reprint Cerebral glucose metabolism in diabetes mellitus
    Anthony L McCall
    Division of Endocrinology, Department of Internal Medicine, Diabetes and Hormone Center of Excellence, University of Virginia School of Medicine, 450 Ray C Hunt Drive, Charlottesville, VA 22908, USA
    Eur J Pharmacol 490:147-58. 2004
  2. ncbi request reprint Treating type 1 diabetes: from strategies for insulin delivery to dual hormonal control
    A L McCall
    Department of Medicine and Center for Diabetes Technology, University of Virginia, Charlottesville, VA 22908, USA
    Minerva Endocrinol 38:145-63. 2013
  3. doi request reprint Insulin therapy and hypoglycemia
    Anthony L McCall
    Division of Endocrinology, University of Virginia School of Medicine, 450 Ray C Hunt Drive, Charlottesville, VA 22903, USA
    Endocrinol Metab Clin North Am 41:57-87. 2012
  4. pmc The median is not the only message: a clinician's perspective on mathematical analysis of glycemic variability and modeling in diabetes mellitus
    Anthony L McCall
    Department of Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    J Diabetes Sci Technol 3:3-11. 2009
  5. pmc Reduced daily risk of glycemic variability: comparison of exenatide with insulin glargine
    Anthony L McCall
    University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Diabetes Technol Ther 11:339-44. 2009
  6. ncbi request reprint A novel analytical method for assessing glucose variability: using CGMS in type 1 diabetes mellitus
    Anthony L McCall
    Division of Endocrinology and Center for Diabetes and Hormone Excellence, Department of Internal Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    Diabetes Technol Ther 8:644-53. 2006
  7. ncbi request reprint Altered glycemia and brain-update and potential relevance to the aging brain
    Anthony L McCall
    The Diabetes and Hormone Center of Excellence, Department of Internal Medicine, University of Virginia Health System, PO Box 801407, Aurbach Medical Research Building, Charlottesville, VA 22908, USA
    Neurobiol Aging 26:70-5. 2005
  8. ncbi request reprint Hypertension management in patients with diabetic nephropathy
    Anthony L McCall
    University of Virginia Health System, Center for Diabetes and Hormone Excellence, Endocrinology Division, 450 Ray C Hunt Drive, PO Box 801407, Charlottesville, VA 22908, USA
    Curr Hypertens Rep 6:272-9. 2004
  9. ncbi request reprint Reducing CVD risk in type 2 DM
    Anthony L McCall
    Department of Internal Medicine, UVA Health System, Charlottesville, VA 22908, USA
    Curr Diab Rep 3:363-4. 2003
  10. pmc Models of glucagon secretion, their application to the analysis of the defects in glucagon counterregulation and potential extension to approximate glucagon action
    Leon S Farhy
    Department of Medicine, Center for Biomathematical Technology, University of Virginia, Charlottesville, Virginia 22908, USA
    J Diabetes Sci Technol 4:1345-56. 2010

Research Grants

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Cerebral glucose metabolism in diabetes mellitus
    Anthony L McCall
    Division of Endocrinology, Department of Internal Medicine, Diabetes and Hormone Center of Excellence, University of Virginia School of Medicine, 450 Ray C Hunt Drive, Charlottesville, VA 22908, USA
    Eur J Pharmacol 490:147-58. 2004
    ..Neurotransmitter metabolism, cerebral blood flow, blood-brain barrier and microvascular function may all be affected to varying degrees by either hypoglycemia or uncontrolled diabetes mellitus...
  2. ncbi request reprint Treating type 1 diabetes: from strategies for insulin delivery to dual hormonal control
    A L McCall
    Department of Medicine and Center for Diabetes Technology, University of Virginia, Charlottesville, VA 22908, USA
    Minerva Endocrinol 38:145-63. 2013
    ....
  3. doi request reprint Insulin therapy and hypoglycemia
    Anthony L McCall
    Division of Endocrinology, University of Virginia School of Medicine, 450 Ray C Hunt Drive, Charlottesville, VA 22903, USA
    Endocrinol Metab Clin North Am 41:57-87. 2012
    ..Methods to achieve adequate control while focusing on minimizing the risk of hypoglycemia are delineated in this article...
  4. pmc The median is not the only message: a clinician's perspective on mathematical analysis of glycemic variability and modeling in diabetes mellitus
    Anthony L McCall
    Department of Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    J Diabetes Sci Technol 3:3-11. 2009
    ..For the clinician, the incursion of mathematical models that simulate normal and pathophysiological mechanisms of glycemic control is a reality and should be also gradually incorporated into clinical practice...
  5. pmc Reduced daily risk of glycemic variability: comparison of exenatide with insulin glargine
    Anthony L McCall
    University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Diabetes Technol Ther 11:339-44. 2009
    ..In the present study, variability parameters were used to assess effects of exenatide and insulin glargine on risk of acute blood glucose extremes...
  6. ncbi request reprint A novel analytical method for assessing glucose variability: using CGMS in type 1 diabetes mellitus
    Anthony L McCall
    Division of Endocrinology and Center for Diabetes and Hormone Excellence, Department of Internal Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    Diabetes Technol Ther 8:644-53. 2006
    ....
  7. ncbi request reprint Altered glycemia and brain-update and potential relevance to the aging brain
    Anthony L McCall
    The Diabetes and Hormone Center of Excellence, Department of Internal Medicine, University of Virginia Health System, PO Box 801407, Aurbach Medical Research Building, Charlottesville, VA 22908, USA
    Neurobiol Aging 26:70-5. 2005
    ..Improved mechanistic understanding of altered glycemia's effects could prevent the adverse impact of diabetes upon the CNS and give new insights into effects that may exist in normal aging...
  8. ncbi request reprint Hypertension management in patients with diabetic nephropathy
    Anthony L McCall
    University of Virginia Health System, Center for Diabetes and Hormone Excellence, Endocrinology Division, 450 Ray C Hunt Drive, PO Box 801407, Charlottesville, VA 22908, USA
    Curr Hypertens Rep 6:272-9. 2004
    ..Therapies not directed specifically at hypertension may also significantly aid hypertension management in prevention of progressive nephropathy, comorbidities, and mortality...
  9. ncbi request reprint Reducing CVD risk in type 2 DM
    Anthony L McCall
    Department of Internal Medicine, UVA Health System, Charlottesville, VA 22908, USA
    Curr Diab Rep 3:363-4. 2003
  10. pmc Models of glucagon secretion, their application to the analysis of the defects in glucagon counterregulation and potential extension to approximate glucagon action
    Leon S Farhy
    Department of Medicine, Center for Biomathematical Technology, University of Virginia, Charlottesville, Virginia 22908, USA
    J Diabetes Sci Technol 4:1345-56. 2010
    ..It may also be used to examine therapeutic responses...
  11. pmc Pancreatic network control of glucagon secretion and counterregulation
    Leon S Farhy
    Department of Medicine, Center for Biomathematical Technology, University of Virginia, Charlottesville, Virginia, USA
    Methods Enzymol 467:547-81. 2009
    ..One advantage of this construct is that all model components are clinically measurable, thereby permitting its transfer, validation, and application to the study of the GCR abnormalities of the human endocrine pancreas in vivo...
  12. pmc System-level control to optimize glucagon counterregulation by switch-off of α-cell suppressing signals in β-cell deficiency
    Leon S Farhy
    Department of Medicine, Center for Biomathematical Technology, University of Virginia, Charlottesville, Virginia 22908, USA
    J Diabetes Sci Technol 3:21-33. 2009
    ..The data indicate that these signals act by different mechanisms, and here we analyze the differences between the two switch offs (SOs) and predict the GCR-amplifying effect of their individual or combined application...
  13. pmc Resolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation
    Xiaolun Huang
    Department of Surgery, University of Virginia, Charlottesville, Virginia 22908, USA
    Endocr Rev 29:603-30. 2008
    ..This review focuses on interactions between the technical, immunological, and metabolic barriers that must be overcome to optimize the success of this important therapeutic approach...
  14. pmc Association of Basal hyperglucagonemia with impaired glucagon counterregulation in type 1 diabetes
    Leon S Farhy
    Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Charlottesville, VA, USA
    Front Physiol 3:40. 2012
    ..Our findings support the hypothesis that basal hyperglucagonemia contributes to the GCR impairment in T1DM and show that the predictive power of our GCR animal model applies to human pathophysiology in T1DM...
  15. ncbi request reprint Diabetes mellitus and the central nervous system
    Anthony L McCall
    University of Virginia School of Medicine, Division of Endocrinology and Metabolism, Department of Internal Medicine, UVA Health System, Charlottesville, Virginia 22908, USA
    Int Rev Neurobiol 51:415-53. 2002
  16. pmc Amplification of pulsatile glucagon counterregulation by switch-off of alpha-cell-suppressing signals in streptozotocin-treated rats
    Leon S Farhy
    University of Virginia Health System, Charlottesville, VA 22908, USA
    Am J Physiol Endocrinol Metab 295:E575-85. 2008
    ..The results of this proof-of-concept interdisciplinary study support the hypothesis that GCR develops as a rebound pulsatile response of the intrapancreatic endocrine feedback network to switch-off of alpha-cell-inhibiting islet signals...
  17. ncbi request reprint Starting insulin therapy in type 2 diabetes: lesson 2
    Anthony L McCall
    Curr Diab Rep 5:326-8. 2005
  18. ncbi request reprint Starting insulin therapy in type 2 diabetes: lesson 1
    Anthony L McCall
    Curr Diab Rep 5:325-6. 2005
  19. ncbi request reprint Does a weight loss medicine make sense for obese type 2 diabetes? New information on endocannabinoid blockers
    Anthony L McCall
    Curr Diab Rep 7:329-32. 2007

Research Grants1

  1. GLUCOCORTICOIDS, HYPOGLYCEMIA & BRAIN GLUCOSE TRANSPORT
    Anthony McCall; Fiscal Year: 2001
    ..These studies should provide insight into hypoglycemia's impact upon the brain. They may potentially lead to safer was to achieve good diabetes control. ..