Research Topics
| ANDREW MAUDSLEYSummaryAffiliation: University of Miami Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Evaluation of variable line-shape models and prior information in automated 1H spectroscopic imaging analysisBrian J Soher
University of Miami School of Medicine, MR Center M896, P O Box 019132, FL 33101, USA
Magn Reson Med 52:1246-54. 2004..The use of prior line-shape information was of most benefit when applied toward setting optimization constraints but was of limited benefit when used to define initial starting values...
Detection and correction of frequency instabilities for volumetric 1H echo-planar spectroscopic imagingAndreas Ebel
Department of Radiology, University of Miami School of Medicine, Miami, Florida, USA
Magn Reson Med 53:465-9. 2005....
Associations of age, gender and body mass with 1H MR-observed brain metabolites and tissue distributionsA A Maudsley
Department of Radiology, University of Miami School of Medicine, Miami, FL 33136, USA
NMR Biomed 25:580-93. 2012..There is, however, sufficient evidence to warrant the inclusion of body weight as a subject selection parameter, secondary to age, and as a factor in data analysis for MRS studies of some brain regions...
Application of volumetric MR spectroscopic imaging for localization of neocortical epilepsyAndrew A Maudsley
Department of Radiology, University of Miami School of Medicine, Miami, FL 33136, USA
Epilepsy Res 88:127-38. 2010..The aim of this study was to evaluate volumetric proton magnetic resonance spectroscopic imaging (MRSI) for localization of epileptogenic foci in neocortical epilepsy...
Reproducibility of serial whole-brain MR spectroscopic imagingA A Maudsley
Department of Radiology, University of Miami School of Medicine, Miami, FL 33136, USA
NMR Biomed 23:251-6. 2010....
Mapping of brain metabolite distributions by volumetric proton MR spectroscopic imaging (MRSI)A A Maudsley
Department of Radiology, Miller School of Medicine, University of Miami, Miami, Florida 33136, USA
Magn Reson Med 61:548-59. 2009..The resultant data provide a normative reference for subsequent utilization for studies of brain injury and disease...
Comprehensive processing, display and analysis for in vivo MR spectroscopic imagingA A Maudsley
Department of Radiology, MR Center, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
NMR Biomed 19:492-503. 2006....
Numerical simulation of PRESS localized MR spectroscopyAndrew A Maudsley
Department of Radiology, University of Miami School of Medicine, 1115 NW 14th St, Miami, FL 33136, USA
J Magn Reson 173:54-63. 2005....
Reproducibility of 3D proton spectroscopy in the human brainBelinda S Y Li
Department of Radiology, New York University School of Medicine, New York, New York 10016, USA
Magn Reson Med 47:439-46. 2002..3%, 9.5%, and 9.7%. The measurement uncertainties can be reduced at a cost of either spatial resolution (by using larger voxels) or time (by performing serial follow-ups)...
Observation of coupled 1H metabolite resonances at long TEBrian J Soher
Department of Radiology, University of Miami School of Medicine, Miami, Florida, USA
Magn Reson Med 53:1283-7. 2005..The spectral analysis for spectra with longer TE times also showed less variability due the higher metabolite SNR, simpler spectral patterns, and the decreased baseline contributions...
Whole-brain proton MR spectroscopic imaging of mild-to-moderate traumatic brain injury and correlation with neuropsychological deficitsVaran Govind
Department of Radiology, University of Miami School of Medicine, Miami, Florida 33136, USA
J Neurotrauma 27:483-96. 2010..These results demonstrate that significant and widespread alterations of brain metabolites occur as a result of mild-to-moderate TBI, and that these measures correlate with measures of cognitive performance...
Improved spectral quality for 3D MR spectroscopic imaging using a high spatial resolution acquisition strategyAndreas Ebel
Northern California Institute for Research and Education, DVA Medical Center San Francisco, MR Unit 114M, 4150 Clement Street, San Francisco, CA 94121, USA
Magn Reson Imaging 21:113-20. 2003..However, the effect of the increased noise was largely offset by the improved spectral quality, leading to an overall improvement of the metabolite image quality obtained using automated spectral analysis...
Improved reconstruction for MR spectroscopic imagingYufang Bao
MR Center R308, 1115 NW 14th Street, Department of Radiology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
IEEE Trans Med Imaging 26:686-95. 2007..Additional preprocessing steps are also proposed to avoid difficulties associated with image regions containing spectra of inadequate quality, which are commonly present in the in vivo MRSI data...
GAVA: spectral simulation for in vivo MRS applicationsBrian J Soher
Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710, USA
J Magn Reson 185:291-9. 2007..This application provides a convenient method for generating a priori spectral information used in parametric spectral analyses and for visual examination of the effects of difference pulse sequences and parameter settings...
Comparison of inversion recovery preparation schemes for lipid suppression in 1H MRSI of human brainAndreas Ebel
Northern California Institute for Research and Education, San Francisco, California, USA
Magn Reson Med 49:903-8. 2003..However, it also led to a loss of 37-43% in signal-to-noise ratio (SNR) for metabolites. Thus, SIR appears to be the better choice for suppressing lipid signals and maintaining metabolite sensitivity...
Correction of local B0 shifts in 3D EPSI of the human brain at 4 TAndreas Ebel
Northern California Institute for Research and Education, DVA Medical Center San Francisco, MR Unit 114M, 4150 Clement St, San Francisco, CA 94121, USA
Magn Reson Imaging 25:377-80. 2007..Similar to the results at 1.5 T, the approach provided a high yield of voxels with good spectral quality for 3D EPSI, resulting in improved brain coverage...
Magnetic resonance spectroscopic imaging reconstruction with deformable shape-intensity modelsXiao-Ping Zhu
Magnetic Resonance Unit, VA Medical Center, San Francisco, California 94121, USA
Magn Reson Med 50:474-82. 2003..1-fold with DSM without distorting spectral resolution, thus maintaining all spectral features of the raw, unfiltered data. In conclusion, DSM should be used to achieve high SNR in reconstructing MRSI data...
Can MR spectroscopy ever be simple and effective?Andrew A Maudsley
AJNR Am J Neuroradiol 26:2167. 2005
Achieving sufficient spectral bandwidth for volumetric 1H echo-planar spectroscopic imaging at 4 TeslaAndreas Ebel
Northern California Institute for Research and Education, VA Medical Center San Francisco, San Francisco, CA 94121, USA
Magn Reson Med 54:697-701. 2005..In this Note, limitations of the iFT method are discussed and an alternative, cyclic spectral unwrapping, is proposed, which is based on prior knowledge of typical in vivo spectral patterns...
Volumetric proton spectroscopic imaging of mild traumatic brain injuryVaranavasi Govindaraju
Northern California Institute for Research and Education, MR Spectroscopy Unit, Veterans Affairs Medical Center, San Francisco, California, USA
AJNR Am J Neuroradiol 25:730-7. 2004..Although the association with injury assessment and outcome is weak, this preliminary study demonstrates the applicability of volumetric proton MRSI for evaluating diffuse injury associated with MTBI...
Research Grants
- PROTON MR SPECTROSCOPIC IMAGING OF EPILEPSYANDREW MAUDSLEY; Fiscal Year: 2005..The improved metabolite image reconstruction and regional pH measurement techniques also have potential clinical applications in other areas, such as cancer, stroke, and brain trauma. ..
- PARTNERSHIP FOR MR SPECTROSCOPIC IMAGING DATA PROCESSINGANDREW MAUDSLEY; Fiscal Year: 2006..The developed methods will facilitate increased use of MRSI for diagnostic imaging, encourage the development of standardized MRSI acquisition, processing, and analysis methods, and map metabolite distributions in human brain. ..
- VOLUMETRIC MR MOLECULAR IMAGING OF BRAINANDREW MAUDSLEY; Fiscal Year: 2006..Matson). This development will establish the range and variance of normal metabolite profiles and provide valuable comparative data for numerous clinical investigations that use short-TE 1H MRS. ..
- Data Processing for Clinical MR Spectroscopy and ImagingANDREW MAUDSLEY; Fiscal Year: 2006..Grant support will be directed towards providing awards for student- and postdoctoral- level attendees to attend the meeting. ..
- Volumetric MRSI Evaluation of Traumatic Brain InjuryANDREW MAUDSLEY; Fiscal Year: 2007....
- PARTNERSHIP FOR MR SPECTROSCOPIC IMAGING DATA PROCESSINGANDREW MAUDSLEY; Fiscal Year: 2009....
- Volumetric MRSI Evaluation of Traumatic Brain InjuryAndrew A Maudsley; Fiscal Year: 2010..Patient groups affected by this common injury include sports-related injuries and blast-related concussion. ..
- PARTNERSHIP FOR MR SPECTROSCOPIC IMAGING DATA PROCESSINGAndrew A Maudsley; Fiscal Year: 2010....
- VOLUMETRIC PROTON MR SPECTROSCOPIC IMAGINGANDREW MAUDSLEY; Fiscal Year: 2001..As techniques are developed, they will support ongoing clinical studies investigating changes of brain metabolites associated with Alzheimer's disease and aging, epilepsy, substance abuse, and schizophrenia. ..
- DATA PROCESSING FOR MR SPECTROSCOPIC IMAGINGANDREW MAUDSLEY; Fiscal Year: 2003..This development will support ongoing clinical studies investigating changes of brain metabolites associated with Alzheimer's disease and aging, epilepsy, and multiple sclerosis. ..
- PARTNERSHIP FOR MR SPECTROSCOPIC IMAGING DATA PROCESSINGANDREW MAUDSLEY; Fiscal Year: 2009....
