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| Karen MatthewsSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Do reports of sleep disturbance relate to coronary and aortic calcification in healthy middle-aged women?: Study of Women's Health Across the NationKaren A Matthews
University of Pittsburgh, Department of Psychiatry, 3811 O Hara St, Pittsburgh, PA 15213, United States University of Pittsburgh, Department of Psychology, 210 S Bouquet Street Pittsburgh, PA 15260, United States University of Pittsburgh, Department of Epidemiology, 130 DeSoto St, Pittsburgh, PA 15216, United States Electronic address
Sleep Med 14:282-7. 2013..We evaluated cross-sectional associations between self-reported sleep disturbance and duration and calcification in the coronary arteries (CAC) and aorta (AC) in healthy mid-life women...- Sleep duration and insulin resistance in healthy black and white adolescentsKaren A Matthews
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
Sleep 35:1353-8. 2012..Yet few studies of sleep and insulin resistance have focused on the important developmental period of adolescence. To address this gap, we examined the association of sleep and insulin resistance in healthy adolescents... - Sleep duration and ambulatory blood pressure in black and white adolescentsElizabeth J Mezick
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Hypertension 59:747-52. 2012..These data are consistent with the hypothesis that the cardiovascular consequences of short sleep may begin as early as adolescence... 
Optimistic attitudes protect against progression of carotid atherosclerosis in healthy middle-aged womenKaren A Matthews
Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Psychosom Med 66:640-4. 2004..We evaluated whether pessimists are more likely to show progression in carotid disease than optimists...- Psychological perspectives on pathways linking socioeconomic status and physical healthKaren A Matthews
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Annu Rev Psychol 62:501-30. 2011..Future research should test integrated models rather than taking piecemeal approaches to evidence. Much work remains to be done, but the questions are of great health significance... - Ethnic differences in cardiovascular risk factor burden among middle-aged women: Study of Women's Health Across the Nation (SWAN)Karen A Matthews
Department of Psychiatry, University of Pittsburgh, PA 15213, USA
Am Heart J 149:1066-73. 2005.... - Hostile behaviors predict cardiovascular mortality among men enrolled in the Multiple Risk Factor Intervention TrialKaren A Matthews
University of Pittsburgh, 3811 O Hara St, Pittsburgh, PA 15213, USA
Circulation 109:66-70. 2004.... 
Are psychosocial factors mediators of socioeconomic status and health connections? A progress report and blueprint for the futureKaren A Matthews
Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Ann N Y Acad Sci 1186:146-73. 2010..We offer a blueprint for future research, which we hope contributes to a better understanding of how SES gets under the skin across the life span...- Blood pressure reactivity to psychological stress predicts hypertension in the CARDIA studyKaren A Matthews
University of Pittsburgh, 3811 O Hara St, Pittsburgh, PA, USA
Circulation 110:74-8. 2004..We tested whether BP changes during psychological stress predict incident hypertension in young adults... - Are changes in cardiovascular disease risk factors in midlife women due to chronological aging or to the menopausal transition?Karen A Matthews
Department of Psychiatry and Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Am Coll Cardiol 54:2366-73. 2009.... - Blood pressure dipping and sleep disturbance in African-American and Caucasian men and womenKaren A Matthews
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Am J Hypertens 21:826-31. 2008..Elevated night time/daytime blood pressure (BP) ratios are associated with cardiovascular morbidity and mortality. We evaluated the associations between sleep/awake BP ratios and sleep disturbances... - Are there bi-directional associations between depressive symptoms and C-reactive protein in mid-life women?Karen A Matthews
University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Brain Behav Immun 24:96-101. 2010..To test whether depressive symptoms are related to subsequent C-reactive protein (CRP) levels and/or whether CRP levels are related to subsequent depressive symptoms in mid-life women... - Unfair treatment, discrimination, and ambulatory blood pressure in black and white adolescentsKaren A Matthews
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Health Psychol 24:258-65. 2005..Feeling unfairly treated because of physical appearance may impact blood pressure uniquely during the adolescent transition... - Influence of hormone therapy on the cardiovascular responses to stress of postmenopausal womenKaren A Matthews
University of Pittsburgh School of Medicine, Department of Psychiatry, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Biol Psychol 69:39-56. 2005.... - Association between socioeconomic status and metabolic syndrome in women: testing the reserve capacity modelKaren A Matthews
Department of Psychiatry, University of Pittsburgh, PA 15213, USA
Health Psychol 27:576-83. 2008..In consequence, lower SES persons may experience more negative emotions, leading to adverse health consequences. The authors tested the reserve capacity model in relation to the metabolic syndrome... - Recurrent major depression predicts progression of coronary calcification in healthy women: Study of Women's Health Across the NationKaren A Matthews
Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Psychosom Med 72:742-7. 2010..It is less clear whether depression is related to the progression of atherosclerosis before the onset of CHD events... - Relation of cardiovascular risk factors in women approaching menopause to menstrual cycle characteristics and reproductive hormones in the follicular and luteal phasesKaren A Matthews
Department of Psychiatry, University of Pittsburgh, Pennsylvania 15213, USA
J Clin Endocrinol Metab 91:1789-95. 2006..Menstrual cycle characteristics may be associated with cardiovascular disease (CVD) risk... - Positive and negative attributes and risk for coronary and aortic calcification in healthy womenKaren A Matthews
Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, Pennsylvania 15213, USA
Psychosom Med 68:355-61. 2006..We tested the hypothesis that low positive and high negative affect and cognitions would be related to risk for coronary and aortic calcification in healthy women... - Diurnal cortisol decline is related to coronary calcification: CARDIA studyKaren Matthews
Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Psychosom Med 68:657-61. 2006.... - Associations between depressive symptoms and inflammatory/hemostatic markers in women during the menopausal transitionKaren A Matthews
Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Psychosom Med 69:124-30. 2007..To test whether depressive symptoms are related to inflammatory and hemostatic markers in women approaching menopause... - Premenopausal risk factors for coronary and aortic calcification: a 20-year follow-up in the healthy women studyKaren A Matthews
University of Pittsburgh, Department of Psychiatry, Epidemiology and Psychology, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Prev Med 45:302-8. 2007..It is important to understand the early development of subclinical cardiovascular disease (CVD) in women to prevent costly morbidity and mortality associated with CVD events... - Indices of socioeconomic position across the life course as predictors of coronary calcification in black and white men and women: coronary artery risk development in young adults studyKaren A Matthews
Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Soc Sci Med 73:768-74. 2011..Our results are the first to show that SES, measured retrospectively and prospectively in multiple ways, is related to CAC, and the first to document the effects primarily in blacks... - Associations of Framingham risk score profile and coronary artery calcification with sleep characteristics in middle-aged men and women: Pittsburgh SleepSCORE studyKaren A Matthews
University of Pittsburgh, Department of Psychiatry, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Sleep 34:711-6. 2011..Short and less efficient sleep may be risk factors for atherosclerosis. Few studies have investigated the associations between sleep characteristics and early cardiovascular disease (CVD) risk... - Blood pressure reactivity to psychological stress and coronary calcification in the Coronary Artery Risk Development in Young Adults StudyKaren A Matthews
University of Pittsburgh, Pittsburgh, PA 15213, USA
Hypertension 47:391-5. 2006..Blood pressure reactivity may provide useful prognostic information about future risk beyond standard risk factors... - Does the menopausal transition affect health-related quality of life?Karen A Matthews
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Am J Med 118:25-36. 2005..There is a clear need for understanding the effects of the menopause beyond the domain of symptoms and to consider whether some domains of HRQOL may improve... - Psychological perspectives on the development of coronary heart diseaseKaren A Matthews
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Am Psychol 60:783-96. 2005..It offers and provides preliminary evidence for a model that integrates socioeconomic status, environmental stress, and person-level factors from a life span perspective... - Are inflammatory and coagulation biomarkers related to sleep characteristics in mid-life women?: Study of Women's Health across the Nation sleep studyKaren A Matthews
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Sleep 33:1649-55. 2010.... - Reproductive hormones and obesity: 9 years of observation from the Study of Women's Health Across the NationKim Sutton-Tyrrell
Department of Epidemiology, University of Pittsburgh, Pennsylvania 15261, USA
Am J Epidemiol 171:1203-13. 2010.... - Sex-hormone-binding globulin and the free androgen index are related to cardiovascular risk factors in multiethnic premenopausal and perimenopausal women enrolled in the Study of Women Across the Nation (SWAN)Kim Sutton-Tyrrell
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 127 Parran Hall 130 DeSoto St, Pittsburgh, PA 15261, USA
Circulation 111:1242-9. 2005..Recent clinical trials have shifted attention away from estrogens and toward androgens and sex hormone-binding globulin (SHBG) as potential mediators of increasing cardiovascular (CV) risk in women at midlife... - Sex steroid hormone profiles are related to sleep measures from polysomnography and the Pittsburgh Sleep Quality IndexMary Fran Sowers
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48104, USA
Sleep 31:1339-49. 2008..To relate reproductive hormones (and the preceding 7-year rates of their change) to objectively and subjectively assessed sleep measures, independent of age, vasomotor symptom frequency, depressive symptoms, and body size... - Endogenous sex hormones impact the progression of subclinical atherosclerosis in women during the menopausal transitionSamar R El Khoudary
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States
Atherosclerosis 225:180-6. 2012.... - Sleep disturbance during the menopausal transition in a multi-ethnic community sample of womenHoward M Kravitz
Rush University Medical Center, Department of Psychiatry, Rush West Campus, 2150 West Harrison Street, Chicago, IL, USA
Sleep 31:979-90. 2008.... - Associations between psychological traits and endothelial function in postmenopausal womenKelly F Harris
Department of Psychology, University of Pittsburgh, PA 15213, USA
Psychosom Med 65:402-9. 2003..HRT use may mask some associations between psychosocial risk factors and endothelial dysfunction among postmenopausal women... - Lipid-lowering medication use and aggression scores in women: a report from the NHLBI-sponsored WISE studyMarian B Olson
Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
J Womens Health (Larchmt) 17:187-94. 2008..The aim of this study was to examine the association between the use of lipid-lowering medication and aggressive responding, hostility, cynicism, and depression scores in women undergoing coronary angiography... - Social relationships and negative emotional traits are associated with central adiposity and arterial stiffness in healthy adolescentsAimee J Midei
Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA
Health Psychol 28:347-53. 2009..We examined the role of social relationships and negative emotional traits in the development of central adiposity and arterial stiffness in healthy adolescents... - Low life purpose and high hostility are related to an attenuated decline in nocturnal blood pressureElizabeth J Mezick
Department of Psychology, University of Pittsburgh, PA 15213, USA
Health Psychol 29:196-204. 2010..We investigated whether positive and negative psychological attributes were associated with sleep-wake BP ratios and examined sleep parameters as potential mediators of these relationships... - African-American ethnicity and cardiovascular risk factors are related to aortic pulse-wave velocity progressionMehret S Birru
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Am J Hypertens 24:809-15. 2011..Little is known about the relationships between CVD risk factors and PWV progression among women transitioning through the menopause, or whether these relationships vary by ethnicity... - Effect modification of obesity on associations between endogenous steroid sex hormones and arterial calcification in women at midlifeSamar R El Khoudary
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
Menopause 18:906-14. 2011..The aim of this study was to examine whether obesity modifies the effects of endogenous steroid sex hormones on arterial calcification in women at midlife... - Cardiovascular risk factors associated with enlarged diameter of the abdominal aortic and iliac arteries in healthy womenAmi S Patel
Department of Epidemiology, University of Pittsburgh, 127 Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
Atherosclerosis 178:311-7. 2005..Women at mid-life should continue to be targeted for weight interventions to reduce their risk for more serious cardiovascular complications... - Social status and health: a comparison of British civil servants in Whitehall-II with European- and African-Americans in CARDIANancy Adler
Department of Psychiatry, University of California at San Francisco, San Francisco, CA 94118, USA
Soc Sci Med 66:1034-45. 2008..Overall, relationships of SSS and health were stronger for Whitehall-II and white CARDIA participants than for blacks in CARDIA... - Influence of race and socioeconomic status on sleep: Pittsburgh SleepSCORE projectElizabeth J Mezick
Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Psychosom Med 70:410-6. 2008..To examine the independent and interactive effects of race and socioeconomic status (SES) on objective indices and self-reports of sleep... - Subclinical atherosclerosis in multiple vascular beds: an index of atherosclerotic burden evaluated in postmenopausal womenKim Sutton-Tyrrell
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, Pittsburgh, PA 15261, USA
Atherosclerosis 160:407-16. 2002..Women with lower premenopausal risk factors did not develop high levels of subclinical atherosclerosis, suggesting that atherosclerosis is a preventable disease in women... - Poor sleep is associated with poorer physical performance and greater functional limitations in older womenSuzanne E Goldman
Department of Epidemiology, University ofPittsburgh, Pittsburgh, PA, USA
Sleep 30:1317-24. 2007..This study examined the association between disturbed sleep and poorer daytime function in older women... - Depressive symptoms, race, and circulating C-reactive protein: the Coronary Artery Risk Development in Young Adults (CARDIA) studyDenise Janicki Deverts
Psychology Department, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA
Psychosom Med 72:734-41. 2010..To examine the prospective association of depressive symptoms with circulating C-reactive protein (CRP) and to determine the direction of that association... - Childhood abuse is associated with adiposity in midlife women: possible pathways through trait anger and reproductive hormonesAimee J Midei
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Psychosom Med 72:215-23. 2010..To examine the association between childhood abuse/neglect and central adiposity and obesity in a sample of 311 women (n = 106 black, 205 white) from the Pittsburgh site of the Study of Women's Health Across the Nation (SWAN)... - Depression symptom severity and reported treatment history in the prediction of cardiac risk in women with suspected myocardial ischemia: The NHLBI-sponsored WISE studyThomas Rutledge
Department of Psychiatry, VA San Diego Healthcare System and University of California, San Diego, CA 92161, USA
Arch Gen Psychiatry 63:874-80. 2006..Typically, however, studies in this area focus only on baseline symptom severity and lack any data concerning symptom duration or symptom history... - Hormone therapy, lipoprotein subclasses, and coronary calcification: the Healthy Women StudyRachel H Mackey
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, Pittsburgh, PA 15261, USA
Arch Intern Med 165:510-5. 2005..To test this hypothesis, we evaluated differences in coronary calcification, lipids, and lipoprotein subclasses among HT users and nonusers in a longitudinal study of the menopause... - Sleep apnea is related to the atherogenic phenotype, lipoprotein subclass BFaith S Luyster
School of Nursing, University of Pittsburgh, Pittsburgh, PA, USA
J Clin Sleep Med 8:155-61. 2012..We examined the relationship between sleep apnea and LDL subclass B, considering body size... - Lipoprotein subclasses and coronary artery calcium in postmenopausal women from the healthy women studyRachel H Mackey
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
Am J Cardiol 90:71i-76i. 2002..These results suggest that the measurement of lipoprotein subclasses may improve the prediction of CAD in postmenopausal women beyond that provided by the conventional lipid panel and CAD risk factors... - Socioeconomic status, antioxidant micronutrients, and correlates of oxidative damage: the Coronary Artery Risk Development in Young Adults (CARDIA) studyDenise Janicki-Deverts
Department of Psychology, Caregie Mellon University, 5000 Forbes Avenue, Pittsburgh, Pennsylvania 15213, USA
Psychosom Med 71:541-8. 2009..Risk for chronic disease increases with decreasing SES. One pathway by which low SES might influence disease risk is by promoting oxidative stress... - Lifetime history of depression and carotid atherosclerosis in middle-aged womenDeborah J Jones
University of Pittsburgh, PA, USA
Arch Gen Psychiatry 60:153-60. 2003..CONCLUSIONS: Recurrent major depressive episodes may be a risk factor for subclinical atherosclerosis. Prevention of recurrent episodes may also prevent further progression of atherosclerosis... - History of unemployment predicts future elevations in C-reactive protein among male participants in the Coronary Artery Risk Development in Young Adults (CARDIA) StudyDenise Janicki-Deverts
Department of Psychology, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA
Ann Behav Med 36:176-85. 2008..Unemployment is associated with risk of future morbidity and premature mortality... - Incident coronary artery calcium among postmenopausal womenLewis H Kuller
Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, United States
Atherosclerosis 200:278-85. 2008.... - Cardiac vagal activity during psychological stress varies with social functioning in older womenVictoria B Egizio
Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Psychophysiology 45:1046-54. 2008..These findings are at apparent odds with the polyvagal theory; however, they complement prior work suggesting that emotional self-regulation could plausibly modulate cardiac vagal control in association with social functioning... - Does who you marry matter for your health? Influence of patients' and spouses' personality on their partners' psychological well-being following coronary artery bypass surgeryJohn M Ruiz
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
J Pers Soc Psychol 91:255-67. 2006..Relationship satisfaction moderated these effects. These results suggest that partners' personality traits are important determinants of both patients' and their caregiving spouses' well-being... - Chronic stress burden, discrimination, and subclinical carotid artery disease in African American and Caucasian womenWendy M Troxel
Department of Psychiatry, University of Pittsburgh, Pennsylvania 15213, USA
Health Psychol 22:300-9. 2003..The results suggest that African Americans may be particularly vulnerable to the burden of chronic stress... - Short-term suppression of ovarian function and immune measures in healthy womenJanine D Flory
Department of Psychology, University of Pittsburgh, PA, USA
Psychoneuroendocrinology 27:749-68. 2002..Basal and acute stress-induced cell counts showed moderate to high temporal stability over a six to ten month time interval... - The influence of socioeconomic status and ethnicity on adolescents' exposure to stressful life eventsSonya S Brady
University of Pittsburgh, Pennsylvania 15213, USA
J Pediatr Psychol 27:575-83. 2002..Correlations between socioeconomic indices were not so high as to suggest redundancy, and different SES indicators were of importance in predicting exposure to different types of life events... - Effects of media violence on health-related outcomes among young menSonya S Brady
University of Pittsburgh, Pittsburgh, PA, USA
Arch Pediatr Adolesc Med 160:341-7. 2006.... - It is never too late: change in physical activity fosters change in cardiovascular risk factors in middle-aged womenJane F Owens
University of Pittsburgh, Department of Psychiatry, Pittsburgh, PA 15213, USA
Prev Cardiol 6:22-8. 2003..Thus, for middle-aged women going through the menopausal transition, it is never too late to reduce their cardiovascular risk by increasing their activity level... - Progression rates of carotid intima-media thickness and adventitial diameter during the menopausal transitionSamar R El Khoudary
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA15213, USA
Menopause 20:8-14. 2013..The aim of this study is to assess whether the levels and progression rates of carotid intima-media thickness (IMT) and adventitial diameter (AD) vary by menopausal stage... - Symptoms, myocardial ischaemia and quality of life in women: results from the NHLBI-sponsored WISE StudyMarian B Olson
Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
Eur Heart J 24:1506-14. 2003..Our goal was to evaluate health-related quality of life (QOL) in women undergoing angiography for suspected ischaemia... - Lifetime depression history and sexual function in women at midlifeJill M Cyranowski
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Arch Sex Behav 33:539-48. 2004..Future research is needed to characterize the temporal and etiologic relationships among lifetime depressive disorder, current mood state, and sexual function in women across the lifespan... - Intra-individual variability in sleep duration and fragmentation: associations with stressElizabeth J Mezick
University of Pittsburgh, Department of Psychology, Pittsburgh, PA, United States
Psychoneuroendocrinology 34:1346-54. 2009..These results may have implications for both sleep and health research... - Socioeconomic status variables predict cardiovascular disease risk factors and prospective mortality risk among women with chest pain. The WISE StudyThomas Rutledge
University of Pittsburgh, USA
Behav Modif 27:54-67. 2003..4, 5.2), including after adjusting for proposed psychosocial and behavioral variables (RR = 5.9, 95% CI 1.2-29.7). Future research will require a thorough a priori focus on potential mechanisms to better understand SES effects on health... - Health services research in the privacy ageRachel Hess
Division of General Internal Medicine, Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
J Gen Intern Med 20:1045-9. 2005..Strengthened regulations concerning privacy of health information are affecting large-scale health outcomes research... - Depressive symptoms during the menopausal transition: the Study of Women's Health Across the Nation (SWAN)Joyce T Bromberger
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States
J Affect Disord 103:267-72. 2007..This study examined the longitudinal relationship between changes in menopausal status and the risk of clinically relevant depressive symptoms and whether the relationship differed according to initial depressive symptom level... - Gain in adiposity across 15 years is associated with reduced gray matter volume in healthy womenIsabella Soreca
Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Psychosom Med 71:485-90. 2009..Cross-sectional results indicate that reduced GMV may be associated with excess body weight... - Socioeconomic trajectories and incident hypertension in a biracial cohort of young adultsKaren A Matthews
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Penn 15213, USA
Hypertension 39:772-6. 2002..A dynamic index of socioeconomic status may be a useful concept in understanding the effects of socioeconomic status on the natural history of hypertension... - Gains in body fat and vasomotor symptom reporting over the menopausal transition: the study of women's health across the nationRebecca C Thurston
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Am J Epidemiol 170:766-74. 2009..The relations between body fat changes and night sweats were not statistically significant. Body fat gains are associated with greater hot flash reporting during the menopausal transition... - Chronic life stress, cardiovascular reactivity, and subclinical cardiovascular disease in adolescentsCarissa A Low
Departments of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Psychosom Med 71:927-31. 2009..To examine cross-sectional and longitudinal relationships between chronic life stress, cardiovascular reactivity, and a marker of subclinical cardiovascular disease in a multiethnic sample of adolescents... - Longitudinal change in reproductive hormones and depressive symptoms across the menopausal transition: results from the Study of Women's Health Across the Nation (SWAN)Joyce T Bromberger
University of Pittsburgh, Pittsburgh, PA 15213, USA
Arch Gen Psychiatry 67:598-607. 2010..Results from clinical and epidemiological studies have been inconsistent. It remains unclear whether alterations in serum hormone levels across the menopausal transition are linked to depressive symptoms... - Marital/cohabitation status and history in relation to sleep in midlife womenWendy M Troxel
Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Sleep 33:973-81. 2010..To examine whether current and/or history of marital/cohabitation status are associated with sleep, independent of demographic and general health risk factors... - Napping, nighttime sleep, and cardiovascular risk factors in mid-life adultsJane F Owens
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Clin Sleep Med 6:330-5. 2010..To evaluate the relations between sleep characteristics and cardiovascular risk factors and napping behavior, and to assess whether daytime napping leads to subsequent better or worse sleep... - Sleep symptoms predict the development of the metabolic syndromeWendy M Troxel
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Sleep 33:1633-40. 2010..This is the first prospective study to report the association between commonly reported sleep symptoms and the development of the metabolic syndrome, a key CVD risk factor... - Stability of children's and adolescents' hemodynamic responses to psychological challenge: a three-year longitudinal study of a multiethnic cohort of boys and girlsKaren A Matthews
Department of Psychiatry, University of Pittsburgh, Pennsylvania 15213, USA
Psychophysiology 39:826-34. 2002..These results suggest that hemodynamic responses to stress change with aging during childhood and adolescence and that they can be measured reliably... - Race and financial strain are independent correlates of sleep in midlife women: the SWAN sleep studyMartica H Hall
Department of Psychiatry University of Pittsburgh, Pittsburgh, PA 15213, USA
Sleep 32:73-82. 2009..To examine racial differences in sleep in a large cohort of midlife women and to evaluate whether indices of socioeconomic status (SES) are associated with racial differences in sleep... - Relationships between the Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), and clinical/polysomnographic measures in a community sampleDaniel J Buysse
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
J Clin Sleep Med 4:563-71. 2008.... - The relation between perceived unfair treatment and blood pressure in a racially/ethnically diverse sample of womenCharlotte Brown
Department of Psychiatry, University of Pittsburgh, PA 15213, USA
Am J Epidemiol 164:257-62. 2006..Although racial/ethnic differences in blood pressure were evident, high levels of perceived unfair treatment were not a correlate of elevated blood pressure... - Heightened functional neural activation to psychological stress covaries with exaggerated blood pressure reactivityPeter J Gianaros
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Hypertension 49:134-40. 2007..Heightened stressor-induced activation of cingulate, prefrontal, insular, and cerebellar brain areas may represent a functional neural phenotype that characterizes individuals who are prone to show exaggerated cardiovascular reactivity... - Unfair treatment and trait anger in relation to nighttime ambulatory blood pressure in African American and white adolescentsDanielle L Beatty
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Psychosom Med 71:813-20. 2009.... - Social networks and marital status predict mortality in older women: prospective evidence from the Study of Osteoporotic Fractures (SOF)Thomas Rutledge
Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Psychosom Med 65:688-94. 2003..To assess the relationship between social network size and prospective mortality risk among a large sample of older, Caucasian women... - Racial differences in perception of healthy body weight in midlife women: results from the Do Stage Transitions Result in Detectable Effects studySemara Thomas
Department of Obstetrics and Gynecology, University of Virginia, Charlottesville, VA, USA
Menopause 20:269-73. 2013..Midlife is a critical period for women that typically includes weight gain. We assessed the associations between perception of healthy body weight and body mass index (BMI) and whether they vary by race... - Trait anger and the metabolic syndrome predict progression of carotid atherosclerosis in healthy middle-aged womenK Raikkonen
University of Helsinki, Department of Psychology, Helsinki, Finland
Psychosom Med 66:903-8. 2004..We tested to see if high levels of the attitudinal and emotional aspects of hostility lead to progression of carotid atherosclerosis in women and if the metabolic syndrome is a mediator of the association... - Depressive symptoms and stressful life events predict metabolic syndrome among middle-aged women: a comparison of World Health Organization, Adult Treatment Panel III, and International Diabetes Foundation definitionsKatri Raikkonen
Department of Psychology, University of Helsinki, Helsinki, Finland
Diabetes Care 30:872-7. 2007..We evaluated whether psychosocial factors that are related to cardiovascular disease and type 2 diabetes predict prospectively the risk for the metabolic syndrome using the different clinical criteria available for defining the syndrome... - Depressive symptoms, insulin resistance, and risk of diabetes in women at midlifeSusan A Everson-Rose
Department of Preventive Medicine, Rush University Medical Center, 1700 W Van Buren St, Suite 470, Chicago, IL 60612, USA
Diabetes Care 27:2856-62. 2004..To examine depression and 3-year change in insulin resistance and risk of diabetes and whether associations vary by race... - Helping midlife women predict the onset of the final menses: SWAN, the Study of Women's Health Across the NationNanette Santoro
Department of Obstetrics, Gynecology and Women s Health, Albert Einstein College of Medicine, New York, NY 10461, USA
Menopause 14:415-24. 2007..Women approaching menopause often ask their doctors, "When are my periods going to end?" The objective of this study was to predict time to the final menstrual period (FMP)... - Reproductive hormones in the early menopausal transition: relationship to ethnicity, body size, and menopausal statusJohn F Randolph
Clinical Centers: University of Michigan, Ann Arbor, Michigan 48109, USA
J Clin Endocrinol Metab 88:1516-22. 2003..All hormone concentrations were significantly correlated with body mass index. We conclude that serum sex steroid, FSH, and SHBG levels vary by ethnicity, but are highly confounded by ethnic disparities in body size... - Education, 15-year risk factor progression, and coronary artery calcium in young adulthood and early middle age: the Coronary Artery Risk Development in Young Adults studyLijing L Yan
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill 60611, USA
JAMA 295:1793-800. 2006.... - Physical activity and changes in weight and waist circumference in midlife women: findings from the Study of Women's Health Across the NationBarbara Sternfeld
Division of Research, Kaiser Permanente, Oakland, CA 94611, USA
Am J Epidemiol 160:912-22. 2004.... - Cardiovascular reactivity during social and nonsocial stressors: do children's personal goals and expressive skills matter?Edith Chen
Department of Psychology, Washington University, St Louis, Missouri 63130, USA
Health Psychol 21:16-24. 2002..Personal strivings and expressive skills do matter for understanding cardiovascular responses in children... - Cynical hostility and carotid atherosclerosis in African American and white women: the Study of Women's Health Across the Nation (SWAN) Heart StudySusan A Everson-Rose
Department of Preventive Medicine, Rush University Medical Center, Chicago, IL 60612-2391, USA
Am Heart J 152:982.e7-13. 2006..CONCLUSIONS: Hostility is related to small but significantly greater subclinical atherosclerosis in middle-aged women; this association is not explained by traditional risk factors... - Individual versus neighborhood socioeconomic status and race as predictors of adolescent ambulatory blood pressure and heart rateJennifer J McGrath
Concordia University Montreal, QC, Canada
Soc Sci Med 63:1442-53. 2006..These results have important public health implications as they suggest individual and neighborhood SES and race are linked to cardiovascular risk disparities as early as adolescence... - Chronic exposure to everyday discrimination and coronary artery calcification in African-American women: the SWAN Heart StudyTene T Lewis
Department of Preventive Medicine, Rush University Medical Center, 1700 W Van Buren, Suite 470 Chicago, Illinois 60612, USA
Psychosom Med 68:362-8. 2006..Emerging evidence suggests that exposure to discrimination may be associated with atherosclerosis in African-American women, although research in this area focused on short-term rather than chronic exposure to discriminatory events... - Physiologic markers of chronic stress in premenopausal, middle-aged womenLynda H Powell
Department of Preventive Medicine, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
Psychosom Med 64:502-9. 2002..The purpose of this study was to identify physiological markers of chronic stress in middle-aged women that can be assessed simply and are thus feasible for introduction into large-scale, epidemiologic studies of aging... - Causes and demographic, medical, lifestyle and psychosocial predictors of premature mortality: the CARDIA studyCarlos Iribarren
Division of Research, Kaiser Permanente, Oakland, CA, USA
Soc Sci Med 60:471-82. 2005.... - Ethnic variation in hypertension among premenopausal and perimenopausal women: Study of Women's Health Across the NationDonald M Lloyd-Jones
Division of Cardiology, Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Hypertension 46:689-95. 2005..Treatment and control rates vary considerably across ethnicities. Greater efforts must be made to improve hypertension awareness, treatment, and control in all middle-aged women, particularly those in ethnic minority groups... - Hemostatic factors and estrogen during the menopausal transitionMaryFran R Sowers
Department of Epidemiology, University of Michigan School of Public Health, 339 East Liberty Street, Suite 310, Ann Arbor, Michigan 48104, USA
J Clin Endocrinol Metab 90:5942-8. 2005..Therefore, we evaluated endogenous hormone concentrations, menopause transition stages, and adoption of exogenous hormone use in relation to hemostatic and inflammation marker concentrations in women... - Prenatal and early childhood blood lead levels and cardiovascular functioning in 9(1/2) year old childrenBrooks B Gump
State University of New York College at Oswego, NY 13126, USA
Neurotoxicol Teratol 27:655-65. 2005..Finally, these effects were significant for lead levels considered low, notably, below the 10 microg/dL threshold currently adopted by the CDC for deleterious effects... - Cardiovascular reactivity to work stress predicts subsequent onset of hypertension: the Air Traffic Controller Health Change StudyEileen E Ming
Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
Psychosom Med 66:459-65. 2004..CONCLUSION: A 20-year follow-up of originally normotensive and stage I hypertensive workers suggests that increased systolic blood pressure reactivity to work stress is associated with long-term risk of hypertension... - Ethnic differences in past hysterectomy for benign conditionsLynda H Powell
Department of Preventive Medicine, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL, USA
Womens Health Issues 15:179-86. 2005..CONCLUSION: Because the highest rates occurred in the disadvantaged African American and Hispanic subgroups, and could not be explained by known risk factors, disparity in the form of overuse in these disadvantaged groups may exist...
Research Grants
- ANTECEDENTS OF THE TYPE A BEHAVIOR PATTERNKaren Matthews; Fiscal Year: 2006..This project will contribute to the knowledge base necessary to prevent the early development of sub clinical CVD. ..
- Womens Health Across the NationKaren Matthews; Fiscal Year: 2007..With SWAN III, many of the original goals of SWAN will be brought to fruition. We will build upon the rich foundation developed during SWAN I and II and link these data to important menopause-related and health outcomes in SWAN III. ..
- CARDIOVASCULAR BEHAVIORAL MEDICINE RESEARCH TRAININGKaren Matthews; Fiscal Year: 2007..Support is requested for five postdoctoral, five predoctoral, and two short-term summer trainees. ..
- Stress, Sleep and Emerging CVD Risk FactorsKaren Matthews; Fiscal Year: 2007..The study will provide novel data testing the relationships of daytime stressful events, SDB, and other nocturnal physiological measures with the emerging risk factors and subclinical CVD measured in HeartSCORE. ..
- Pittsburgh Mind-Body Center-II Summer InstitutesKaren Matthews; Fiscal Year: 2007..We anticipate that 30 scientists will attend the Summer Institute each year, with 20 from outside Western Pennsylvania. ..
- Development of Psychobiological Risk Factors in AdolescenceKaren Matthews; Fiscal Year: 2009..The research has the potential of understanding the basis of adolescent health disparities. ..
- ANTECEDENTS OF THE TYPE A BEHAVIOR PATTERNKaren Matthews; Fiscal Year: 2002..abstract_text> ..
- ANTECEDENTS OF THE TYPE A BEHAVIOR PATTERNKaren Matthews; Fiscal Year: 1991....
- ANTECEDENTS OF THE TYPE A BEHAVIOR BEHAVIOR PATTERNKaren Matthews; Fiscal Year: 1993..The proposed project attempts to add significantly to the understanding of etiology of Black-White and social class differences in cardiovascular risk factors, and the role of hostility in this development...
- Development of Psychobiological Risk Factors in AdolescenceKaren A Matthews; Fiscal Year: 2010..The research has the potential of understanding the basis of adolescent health disparities. ..