Karen Matthews

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. doi request reprint Sleep and risk for high blood pressure and hypertension in midlife women: the SWAN (Study of Women's Health Across the Nation) Sleep Study
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, PA, United States Department of Epidemiology, University of Pittsburgh, PA, United States Department of Psychology, University of Pittsburgh, PA, United States Electronic address
    Sleep Med 15:203-8. 2014
  2. doi request reprint Child abuse is related to inflammation in mid-life women: Role of obesity
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, USA Department of Psychology, University of Pittsburgh, USA Department of Epidemiology, University of Pittsburgh, USA Electronic address
    Brain Behav Immun 36:29-34. 2014
  3. pmc Changes in cardiovascular risk factors by hysterectomy status with and without oophorectomy: Study of Women's Health Across the Nation
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Coll Cardiol 62:191-200. 2013
  4. pmc Do reports of sleep disturbance relate to coronary and aortic calcification in healthy middle-aged women?: Study of women's health across the nation
    Karen A Matthews
    University of Pittsburgh, Department of Psychiatry, Pittsburgh, PA 15213, USA
    Sleep Med 14:282-7. 2013
  5. pmc Sleep duration and insulin resistance in healthy black and white adolescents
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
    Sleep 35:1353-8. 2012
  6. pmc Sleep duration and ambulatory blood pressure in black and white adolescents
    Elizabeth J Mezick
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Hypertension 59:747-52. 2012
  7. ncbi request reprint Relation of cardiovascular risk factors in women approaching menopause to menstrual cycle characteristics and reproductive hormones in the follicular and luteal phases
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, Pennsylvania 15213, USA
    J Clin Endocrinol Metab 91:1789-95. 2006
  8. ncbi request reprint Positive and negative attributes and risk for coronary and aortic calcification in healthy women
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, Pennsylvania 15213, USA
    Psychosom Med 68:355-61. 2006
  9. pmc Are there bi-directional associations between depressive symptoms and C-reactive protein in mid-life women?
    Karen A Matthews
    University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Brain Behav Immun 24:96-101. 2010
  10. ncbi request reprint Blood pressure reactivity to psychological stress and coronary calcification in the Coronary Artery Risk Development in Young Adults Study
    Karen A Matthews
    University of Pittsburgh, Pittsburgh, PA 15213, USA
    Hypertension 47:391-5. 2006

Research Grants

  1. ANTECEDENTS OF THE TYPE A BEHAVIOR PATTERN
    Karen Matthews; Fiscal Year: 2006
  2. Womens Health Across the Nation
    Karen Matthews; Fiscal Year: 2007
  3. CARDIOVASCULAR BEHAVIORAL MEDICINE RESEARCH TRAINING
    Karen Matthews; Fiscal Year: 2007
  4. Stress, Sleep and Emerging CVD Risk Factors
    Karen Matthews; Fiscal Year: 2007
  5. Pittsburgh Mind-Body Center-II Summer Institutes
    Karen Matthews; Fiscal Year: 2007
  6. Development of Psychobiological Risk Factors in Adolescence
    Karen Matthews; Fiscal Year: 2009
  7. ANTECEDENTS OF THE TYPE A BEHAVIOR PATTERN
    Karen Matthews; Fiscal Year: 2002
  8. ANTECEDENTS OF THE TYPE A BEHAVIOR PATTERN
    Karen Matthews; Fiscal Year: 1991
  9. ANTECEDENTS OF THE TYPE A BEHAVIOR BEHAVIOR PATTERN
    Karen Matthews; Fiscal Year: 1993
  10. Development of Psychobiological Risk Factors in Adolescence
    Karen A Matthews; Fiscal Year: 2010

Detail Information

Publications114 found, 100 shown here

  1. doi request reprint Sleep and risk for high blood pressure and hypertension in midlife women: the SWAN (Study of Women's Health Across the Nation) Sleep Study
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, PA, United States Department of Epidemiology, University of Pittsburgh, PA, United States Department of Psychology, University of Pittsburgh, PA, United States Electronic address
    Sleep Med 15:203-8. 2014
    ..Inadequate self-reported sleep is related to high blood pressure (BP). Our study investigated cross-sectional and longitudinal relationships between poor sleep measured by in-home polysomnography (PSG) and BP...
  2. doi request reprint Child abuse is related to inflammation in mid-life women: Role of obesity
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, USA Department of Psychology, University of Pittsburgh, USA Department of Epidemiology, University of Pittsburgh, USA Electronic address
    Brain Behav Immun 36:29-34. 2014
    ..This study examined whether childhood abuse predicted elevated levels of C-reactive protein (CRP) and whether the association was due to body size...
  3. pmc Changes in cardiovascular risk factors by hysterectomy status with and without oophorectomy: Study of Women's Health Across the Nation
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Coll Cardiol 62:191-200. 2013
    ..The aim of this study was to compare the changes in risk factors for cardiovascular disease (CVD) leading up to and after hysterectomy with or without bilateral oophorectomy with the changes observed up to and after natural menopause...
  4. pmc Do reports of sleep disturbance relate to coronary and aortic calcification in healthy middle-aged women?: Study of women's health across the nation
    Karen A Matthews
    University of Pittsburgh, Department of Psychiatry, Pittsburgh, PA 15213, USA
    Sleep Med 14:282-7. 2013
    ..We evaluated cross-sectional associations between self-reported sleep disturbance and duration and calcification in the coronary arteries (CAC) and aorta (AC) in healthy mid-life women...
  5. pmc Sleep duration and insulin resistance in healthy black and white adolescents
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
    Sleep 35:1353-8. 2012
    ..Yet few studies of sleep and insulin resistance have focused on the important developmental period of adolescence. To address this gap, we examined the association of sleep and insulin resistance in healthy adolescents...
  6. pmc Sleep duration and ambulatory blood pressure in black and white adolescents
    Elizabeth J Mezick
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Hypertension 59:747-52. 2012
    ..These data are consistent with the hypothesis that the cardiovascular consequences of short sleep may begin as early as adolescence...
  7. ncbi request reprint Relation of cardiovascular risk factors in women approaching menopause to menstrual cycle characteristics and reproductive hormones in the follicular and luteal phases
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, Pennsylvania 15213, USA
    J Clin Endocrinol Metab 91:1789-95. 2006
    ..Menstrual cycle characteristics may be associated with cardiovascular disease (CVD) risk...
  8. ncbi request reprint Positive and negative attributes and risk for coronary and aortic calcification in healthy women
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, Pennsylvania 15213, USA
    Psychosom Med 68:355-61. 2006
    ..We tested the hypothesis that low positive and high negative affect and cognitions would be related to risk for coronary and aortic calcification in healthy women...
  9. pmc Are there bi-directional associations between depressive symptoms and C-reactive protein in mid-life women?
    Karen A Matthews
    University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Brain Behav Immun 24:96-101. 2010
    ..To test whether depressive symptoms are related to subsequent C-reactive protein (CRP) levels and/or whether CRP levels are related to subsequent depressive symptoms in mid-life women...
  10. ncbi request reprint Blood pressure reactivity to psychological stress and coronary calcification in the Coronary Artery Risk Development in Young Adults Study
    Karen A Matthews
    University of Pittsburgh, Pittsburgh, PA 15213, USA
    Hypertension 47:391-5. 2006
    ..Blood pressure reactivity may provide useful prognostic information about future risk beyond standard risk factors...
  11. ncbi request reprint Does the menopausal transition affect health-related quality of life?
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Am J Med 118:25-36. 2005
    ..There is a clear need for understanding the effects of the menopause beyond the domain of symptoms and to consider whether some domains of HRQOL may improve...
  12. ncbi request reprint Psychological perspectives on the development of coronary heart disease
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am Psychol 60:783-96. 2005
    ..It offers and provides preliminary evidence for a model that integrates socioeconomic status, environmental stress, and person-level factors from a life span perspective...
  13. pmc Blood pressure dipping and sleep disturbance in African-American and Caucasian men and women
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Hypertens 21:826-31. 2008
    ..Elevated night time/daytime blood pressure (BP) ratios are associated with cardiovascular morbidity and mortality. We evaluated the associations between sleep/awake BP ratios and sleep disturbances...
  14. ncbi request reprint Ethnic differences in cardiovascular risk factor burden among middle-aged women: Study of Women's Health Across the Nation (SWAN)
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, PA 15213, USA
    Am Heart J 149:1066-73. 2005
    ....
  15. ncbi request reprint Unfair treatment, discrimination, and ambulatory blood pressure in black and white adolescents
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Health Psychol 24:258-65. 2005
    ..Feeling unfairly treated because of physical appearance may impact blood pressure uniquely during the adolescent transition...
  16. ncbi request reprint Diurnal cortisol decline is related to coronary calcification: CARDIA study
    Karen Matthews
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Psychosom Med 68:657-61. 2006
    ....
  17. ncbi request reprint Associations between depressive symptoms and inflammatory/hemostatic markers in women during the menopausal transition
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Psychosom Med 69:124-30. 2007
    ..To test whether depressive symptoms are related to inflammatory and hemostatic markers in women approaching menopause...
  18. pmc Indices of socioeconomic position across the life course as predictors of coronary calcification in black and white men and women: coronary artery risk development in young adults study
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Soc Sci Med 73:768-74. 2011
    ..Our results are the first to show that SES, measured retrospectively and prospectively in multiple ways, is related to CAC, and the first to document the effects primarily in blacks...
  19. pmc Associations of Framingham risk score profile and coronary artery calcification with sleep characteristics in middle-aged men and women: Pittsburgh SleepSCORE study
    Karen A Matthews
    University of Pittsburgh, Department of Psychiatry, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Sleep 34:711-6. 2011
    ..Short and less efficient sleep may be risk factors for atherosclerosis. Few studies have investigated the associations between sleep characteristics and early cardiovascular disease (CVD) risk...
  20. pmc Recurrent major depression predicts progression of coronary calcification in healthy women: Study of Women's Health Across the Nation
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Psychosom Med 72:742-7. 2010
    ..It is less clear whether depression is related to the progression of atherosclerosis before the onset of CHD events...
  21. pmc Psychological perspectives on pathways linking socioeconomic status and physical health
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Annu Rev Psychol 62:501-30. 2011
    ..Future research should test integrated models rather than taking piecemeal approaches to evidence. Much work remains to be done, but the questions are of great health significance...
  22. doi request reprint Are psychosocial factors mediators of socioeconomic status and health connections? A progress report and blueprint for the future
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Ann N Y Acad Sci 1186:146-73. 2010
    ..We offer a blueprint for future research, which we hope contributes to a better understanding of how SES gets under the skin across the life span...
  23. pmc Are changes in cardiovascular disease risk factors in midlife women due to chronological aging or to the menopausal transition?
    Karen A Matthews
    Department of Psychiatry and Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Am Coll Cardiol 54:2366-73. 2009
    ....
  24. pmc Association between socioeconomic status and metabolic syndrome in women: testing the reserve capacity model
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, PA 15213, USA
    Health Psychol 27:576-83. 2008
    ..In consequence, lower SES persons may experience more negative emotions, leading to adverse health consequences. The authors tested the reserve capacity model in relation to the metabolic syndrome...
  25. pmc Premenopausal risk factors for coronary and aortic calcification: a 20-year follow-up in the healthy women study
    Karen A Matthews
    University of Pittsburgh, Department of Psychiatry, Epidemiology and Psychology, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Prev Med 45:302-8. 2007
    ..It is important to understand the early development of subclinical cardiovascular disease (CVD) in women to prevent costly morbidity and mortality associated with CVD events...
  26. ncbi request reprint Influence of hormone therapy on the cardiovascular responses to stress of postmenopausal women
    Karen A Matthews
    University of Pittsburgh School of Medicine, Department of Psychiatry, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Biol Psychol 69:39-56. 2005
    ....
  27. ncbi request reprint Optimistic attitudes protect against progression of carotid atherosclerosis in healthy middle-aged women
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Psychosom Med 66:640-4. 2004
    ..We evaluated whether pessimists are more likely to show progression in carotid disease than optimists...
  28. ncbi request reprint Hostile behaviors predict cardiovascular mortality among men enrolled in the Multiple Risk Factor Intervention Trial
    Karen A Matthews
    University of Pittsburgh, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Circulation 109:66-70. 2004
    ....
  29. ncbi request reprint Blood pressure reactivity to psychological stress predicts hypertension in the CARDIA study
    Karen A Matthews
    University of Pittsburgh, 3811 O Hara St, Pittsburgh, PA, USA
    Circulation 110:74-8. 2004
    ..We tested whether BP changes during psychological stress predict incident hypertension in young adults...
  30. pmc Are inflammatory and coagulation biomarkers related to sleep characteristics in mid-life women?: Study of Women's Health across the Nation sleep study
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Sleep 33:1649-55. 2010
    ....
  31. pmc Reproductive hormones and obesity: 9 years of observation from the Study of Women's Health Across the Nation
    Kim Sutton-Tyrrell
    Department of Epidemiology, University of Pittsburgh, Pennsylvania 15261, USA
    Am J Epidemiol 171:1203-13. 2010
    ....
  32. ncbi request reprint Sex-hormone-binding globulin and the free androgen index are related to cardiovascular risk factors in multiethnic premenopausal and perimenopausal women enrolled in the Study of Women Across the Nation (SWAN)
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 127 Parran Hall 130 DeSoto St, Pittsburgh, PA 15261, USA
    Circulation 111:1242-9. 2005
    ..Recent clinical trials have shifted attention away from estrogens and toward androgens and sex hormone-binding globulin (SHBG) as potential mediators of increasing cardiovascular (CV) risk in women at midlife...
  33. pmc Sex steroid hormone profiles are related to sleep measures from polysomnography and the Pittsburgh Sleep Quality Index
    Mary Fran Sowers
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48104, USA
    Sleep 31:1339-49. 2008
    ..To relate reproductive hormones (and the preceding 7-year rates of their change) to objectively and subjectively assessed sleep measures, independent of age, vasomotor symptom frequency, depressive symptoms, and body size...
  34. pmc Progression rates of carotid intima-media thickness and adventitial diameter during the menopausal transition
    Samar R El Khoudary
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA15213, USA
    Menopause 20:8-14. 2013
    ..The aim of this study is to assess whether the levels and progression rates of carotid intima-media thickness (IMT) and adventitial diameter (AD) vary by menopausal stage...
  35. pmc African-American ethnicity and cardiovascular risk factors are related to aortic pulse-wave velocity progression
    Mehret S Birru
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Hypertens 24:809-15. 2011
    ..Little is known about the relationships between CVD risk factors and PWV progression among women transitioning through the menopause, or whether these relationships vary by ethnicity...
  36. pmc Effect modification of obesity on associations between endogenous steroid sex hormones and arterial calcification in women at midlife
    Samar R El Khoudary
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Menopause 18:906-14. 2011
    ..The aim of this study was to examine whether obesity modifies the effects of endogenous steroid sex hormones on arterial calcification in women at midlife...
  37. pmc Endogenous sex hormones impact the progression of subclinical atherosclerosis in women during the menopausal transition
    Samar R El Khoudary
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States
    Atherosclerosis 225:180-6. 2012
    ....
  38. pmc Sleep disturbance during the menopausal transition in a multi-ethnic community sample of women
    Howard M Kravitz
    Rush University Medical Center, Department of Psychiatry, Rush West Campus, 2150 West Harrison Street, Chicago, IL, USA
    Sleep 31:979-90. 2008
    ....
  39. ncbi request reprint Associations between psychological traits and endothelial function in postmenopausal women
    Kelly F Harris
    Department of Psychology, University of Pittsburgh, PA 15213, USA
    Psychosom Med 65:402-9. 2003
    ....
  40. pmc Social relationships and negative emotional traits are associated with central adiposity and arterial stiffness in healthy adolescents
    Aimee J Midei
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Health Psychol 28:347-53. 2009
    ..We examined the role of social relationships and negative emotional traits in the development of central adiposity and arterial stiffness in healthy adolescents...
  41. pmc Lipid-lowering medication use and aggression scores in women: a report from the NHLBI-sponsored WISE study
    Marian B Olson
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Womens Health (Larchmt) 17:187-94. 2008
    ..The aim of this study was to examine the association between the use of lipid-lowering medication and aggressive responding, hostility, cynicism, and depression scores in women undergoing coronary angiography...
  42. pmc Low life purpose and high hostility are related to an attenuated decline in nocturnal blood pressure
    Elizabeth J Mezick
    Department of Psychology, University of Pittsburgh, PA 15213, USA
    Health Psychol 29:196-204. 2010
    ..We investigated whether positive and negative psychological attributes were associated with sleep-wake BP ratios and examined sleep parameters as potential mediators of these relationships...
  43. ncbi request reprint Cardiovascular risk factors associated with enlarged diameter of the abdominal aortic and iliac arteries in healthy women
    Ami S Patel
    Department of Epidemiology, University of Pittsburgh, 127 Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Atherosclerosis 178:311-7. 2005
    ..Women at mid-life should continue to be targeted for weight interventions to reduce their risk for more serious cardiovascular complications...
  44. doi request reprint Social status and health: a comparison of British civil servants in Whitehall-II with European- and African-Americans in CARDIA
    Nancy Adler
    Department of Psychiatry, University of California at San Francisco, San Francisco, CA 94118, USA
    Soc Sci Med 66:1034-45. 2008
    ..Overall, relationships of SSS and health were stronger for Whitehall-II and white CARDIA participants than for blacks in CARDIA...
  45. ncbi request reprint Subclinical atherosclerosis in multiple vascular beds: an index of atherosclerotic burden evaluated in postmenopausal women
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Atherosclerosis 160:407-16. 2002
    ..Women with lower premenopausal risk factors did not develop high levels of subclinical atherosclerosis, suggesting that atherosclerosis is a preventable disease in women...
  46. pmc Poor sleep is associated with poorer physical performance and greater functional limitations in older women
    Suzanne E Goldman
    Department of Epidemiology, University ofPittsburgh, Pittsburgh, PA, USA
    Sleep 30:1317-24. 2007
    ..This study examined the association between disturbed sleep and poorer daytime function in older women...
  47. pmc Influence of race and socioeconomic status on sleep: Pittsburgh SleepSCORE project
    Elizabeth J Mezick
    Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Psychosom Med 70:410-6. 2008
    ..To examine the independent and interactive effects of race and socioeconomic status (SES) on objective indices and self-reports of sleep...
  48. ncbi request reprint Hormone therapy, lipoprotein subclasses, and coronary calcification: the Healthy Women Study
    Rachel H Mackey
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Arch Intern Med 165:510-5. 2005
    ..To test this hypothesis, we evaluated differences in coronary calcification, lipids, and lipoprotein subclasses among HT users and nonusers in a longitudinal study of the menopause...
  49. pmc Childhood abuse is associated with adiposity in midlife women: possible pathways through trait anger and reproductive hormones
    Aimee J Midei
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Psychosom Med 72:215-23. 2010
    ..To examine the association between childhood abuse/neglect and central adiposity and obesity in a sample of 311 women (n = 106 black, 205 white) from the Pittsburgh site of the Study of Women's Health Across the Nation (SWAN)...
  50. ncbi request reprint Depression symptom severity and reported treatment history in the prediction of cardiac risk in women with suspected myocardial ischemia: The NHLBI-sponsored WISE study
    Thomas Rutledge
    Department of Psychiatry, VA San Diego Healthcare System and University of California, San Diego, CA 92161, USA
    Arch Gen Psychiatry 63:874-80. 2006
    ..Typically, however, studies in this area focus only on baseline symptom severity and lack any data concerning symptom duration or symptom history...
  51. pmc Depressive symptoms, race, and circulating C-reactive protein: the Coronary Artery Risk Development in Young Adults (CARDIA) study
    Denise Janicki Deverts
    Psychology Department, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA
    Psychosom Med 72:734-41. 2010
    ..To examine the prospective association of depressive symptoms with circulating C-reactive protein (CRP) and to determine the direction of that association...
  52. pmc Sleep apnea is related to the atherogenic phenotype, lipoprotein subclass B
    Faith S Luyster
    School of Nursing, University of Pittsburgh, Pittsburgh, PA, USA
    J Clin Sleep Med 8:155-61. 2012
    ..We examined the relationship between sleep apnea and LDL subclass B, considering body size...
  53. doi request reprint Socioeconomic status, antioxidant micronutrients, and correlates of oxidative damage: the Coronary Artery Risk Development in Young Adults (CARDIA) study
    Denise Janicki-Deverts
    Department of Psychology, Caregie Mellon University, 5000 Forbes Avenue, Pittsburgh, Pennsylvania 15213, USA
    Psychosom Med 71:541-8. 2009
    ..Risk for chronic disease increases with decreasing SES. One pathway by which low SES might influence disease risk is by promoting oxidative stress...
  54. ncbi request reprint Lipoprotein subclasses and coronary artery calcium in postmenopausal women from the healthy women study
    Rachel H Mackey
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Cardiol 90:71i-76i. 2002
    ..These results suggest that the measurement of lipoprotein subclasses may improve the prediction of CAD in postmenopausal women beyond that provided by the conventional lipid panel and CAD risk factors...
  55. ncbi request reprint Lifetime history of depression and carotid atherosclerosis in middle-aged women
    Deborah J Jones
    University of Pittsburgh, PA, USA
    Arch Gen Psychiatry 60:153-60. 2003
    ..We determined the association between lifetime history of major depression and subclinical carotid atherosclerosis in middle-aged women...
  56. ncbi request reprint The influence of socioeconomic status and ethnicity on adolescents' exposure to stressful life events
    Sonya S Brady
    University of Pittsburgh, Pennsylvania 15213, USA
    J Pediatr Psychol 27:575-83. 2002
    ..To test the relations between resource-based and prestige-based measures of socioeconomic status (SES), ethnicity, and life events that varied in valence, dependency on adolescent behavior, and duration...
  57. pmc Incident coronary artery calcium among postmenopausal women
    Lewis H Kuller
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, United States
    Atherosclerosis 200:278-85. 2008
    ....
  58. ncbi request reprint Short-term suppression of ovarian function and immune measures in healthy women
    Janine D Flory
    Department of Psychology, University of Pittsburgh, PA, USA
    Psychoneuroendocrinology 27:749-68. 2002
    ..Basal and acute stress-induced cell counts showed moderate to high temporal stability over a six to ten month time interval...
  59. doi request reprint History of unemployment predicts future elevations in C-reactive protein among male participants in the Coronary Artery Risk Development in Young Adults (CARDIA) Study
    Denise Janicki-Deverts
    Department of Psychology, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA
    Ann Behav Med 36:176-85. 2008
    ..Unemployment is associated with risk of future morbidity and premature mortality...
  60. ncbi request reprint Chronic stress burden, discrimination, and subclinical carotid artery disease in African American and Caucasian women
    Wendy M Troxel
    Department of Psychiatry, University of Pittsburgh, Pennsylvania 15213, USA
    Health Psychol 22:300-9. 2003
    ..The results suggest that African Americans may be particularly vulnerable to the burden of chronic stress...
  61. pmc Cardiac vagal activity during psychological stress varies with social functioning in older women
    Victoria B Egizio
    Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Psychophysiology 45:1046-54. 2008
    ..These findings are at apparent odds with the polyvagal theory; however, they complement prior work suggesting that emotional self-regulation could plausibly modulate cardiac vagal control in association with social functioning...
  62. ncbi request reprint Does who you marry matter for your health? Influence of patients' and spouses' personality on their partners' psychological well-being following coronary artery bypass surgery
    John M Ruiz
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
    J Pers Soc Psychol 91:255-67. 2006
    ..Relationship satisfaction moderated these effects. These results suggest that partners' personality traits are important determinants of both patients' and their caregiving spouses' well-being...
  63. ncbi request reprint It is never too late: change in physical activity fosters change in cardiovascular risk factors in middle-aged women
    Jane F Owens
    University of Pittsburgh, Department of Psychiatry, Pittsburgh, PA 15213, USA
    Prev Cardiol 6:22-8. 2003
    ..Thus, for middle-aged women going through the menopausal transition, it is never too late to reduce their cardiovascular risk by increasing their activity level...
  64. ncbi request reprint Effects of media violence on health-related outcomes among young men
    Sonya S Brady
    University of Pittsburgh, Pittsburgh, PA, USA
    Arch Pediatr Adolesc Med 160:341-7. 2006
    ....
  65. ncbi request reprint Symptoms, myocardial ischaemia and quality of life in women: results from the NHLBI-sponsored WISE Study
    Marian B Olson
    Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Eur Heart J 24:1506-14. 2003
    ..Our goal was to evaluate health-related quality of life (QOL) in women undergoing angiography for suspected ischaemia...
  66. ncbi request reprint Lifetime depression history and sexual function in women at midlife
    Jill M Cyranowski
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Arch Sex Behav 33:539-48. 2004
    ..Future research is needed to characterize the temporal and etiologic relationships among lifetime depressive disorder, current mood state, and sexual function in women across the lifespan...
  67. ncbi request reprint Socioeconomic status variables predict cardiovascular disease risk factors and prospective mortality risk among women with chest pain. The WISE Study
    Thomas Rutledge
    University of Pittsburgh, USA
    Behav Modif 27:54-67. 2003
    ..4, 5.2), including after adjusting for proposed psychosocial and behavioral variables (RR = 5.9, 95% CI 1.2-29.7). Future research will require a thorough a priori focus on potential mechanisms to better understand SES effects on health...
  68. pmc Intra-individual variability in sleep duration and fragmentation: associations with stress
    Elizabeth J Mezick
    University of Pittsburgh, Department of Psychology, Pittsburgh, PA, United States
    Psychoneuroendocrinology 34:1346-54. 2009
    ..These results may have implications for both sleep and health research...
  69. pmc Health services research in the privacy age
    Rachel Hess
    Division of General Internal Medicine, Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Gen Intern Med 20:1045-9. 2005
    ..Strengthened regulations concerning privacy of health information are affecting large-scale health outcomes research...
  70. ncbi request reprint Socioeconomic trajectories and incident hypertension in a biracial cohort of young adults
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Penn 15213, USA
    Hypertension 39:772-6. 2002
    ..A dynamic index of socioeconomic status may be a useful concept in understanding the effects of socioeconomic status on the natural history of hypertension...
  71. ncbi request reprint Stability of children's and adolescents' hemodynamic responses to psychological challenge: a three-year longitudinal study of a multiethnic cohort of boys and girls
    Karen A Matthews
    Department of Psychiatry, University of Pittsburgh, Pennsylvania 15213, USA
    Psychophysiology 39:826-34. 2002
    ..These results suggest that hemodynamic responses to stress change with aging during childhood and adolescence and that they can be measured reliably...
  72. pmc Sleep symptoms predict the development of the metabolic syndrome
    Wendy M Troxel
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Sleep 33:1633-40. 2010
    ..This is the first prospective study to report the association between commonly reported sleep symptoms and the development of the metabolic syndrome, a key CVD risk factor...
  73. pmc Gain in adiposity across 15 years is associated with reduced gray matter volume in healthy women
    Isabella Soreca
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Psychosom Med 71:485-90. 2009
    ..Cross-sectional results indicate that reduced GMV may be associated with excess body weight...
  74. pmc Gains in body fat and vasomotor symptom reporting over the menopausal transition: the study of women's health across the nation
    Rebecca C Thurston
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Am J Epidemiol 170:766-74. 2009
    ..The relations between body fat changes and night sweats were not statistically significant. Body fat gains are associated with greater hot flash reporting during the menopausal transition...
  75. pmc Napping, nighttime sleep, and cardiovascular risk factors in mid-life adults
    Jane F Owens
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Clin Sleep Med 6:330-5. 2010
    ..To evaluate the relations between sleep characteristics and cardiovascular risk factors and napping behavior, and to assess whether daytime napping leads to subsequent better or worse sleep...
  76. pmc Chronic life stress, cardiovascular reactivity, and subclinical cardiovascular disease in adolescents
    Carissa A Low
    Departments of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Psychosom Med 71:927-31. 2009
    ..To examine cross-sectional and longitudinal relationships between chronic life stress, cardiovascular reactivity, and a marker of subclinical cardiovascular disease in a multiethnic sample of adolescents...
  77. pmc Longitudinal change in reproductive hormones and depressive symptoms across the menopausal transition: results from the Study of Women's Health Across the Nation (SWAN)
    Joyce T Bromberger
    University of Pittsburgh, Pittsburgh, PA 15213, USA
    Arch Gen Psychiatry 67:598-607. 2010
    ..Results from clinical and epidemiological studies have been inconsistent. It remains unclear whether alterations in serum hormone levels across the menopausal transition are linked to depressive symptoms...
  78. pmc Race and financial strain are independent correlates of sleep in midlife women: the SWAN sleep study
    Martica H Hall
    Department of Psychiatry University of Pittsburgh, Pittsburgh, PA 15213, USA
    Sleep 32:73-82. 2009
    ..To examine racial differences in sleep in a large cohort of midlife women and to evaluate whether indices of socioeconomic status (SES) are associated with racial differences in sleep...
  79. pmc Relationships between the Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), and clinical/polysomnographic measures in a community sample
    Daniel J Buysse
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
    J Clin Sleep Med 4:563-71. 2008
    ....
  80. pmc Marital/cohabitation status and history in relation to sleep in midlife women
    Wendy M Troxel
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Sleep 33:973-81. 2010
    ..To examine whether current and/or history of marital/cohabitation status are associated with sleep, independent of demographic and general health risk factors...
  81. ncbi request reprint The relation between perceived unfair treatment and blood pressure in a racially/ethnically diverse sample of women
    Charlotte Brown
    Department of Psychiatry, University of Pittsburgh, PA 15213, USA
    Am J Epidemiol 164:257-62. 2006
    ..Although racial/ethnic differences in blood pressure were evident, high levels of perceived unfair treatment were not a correlate of elevated blood pressure...
  82. ncbi request reprint Heightened functional neural activation to psychological stress covaries with exaggerated blood pressure reactivity
    Peter J Gianaros
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Hypertension 49:134-40. 2007
    ..Heightened stressor-induced activation of cingulate, prefrontal, insular, and cerebellar brain areas may represent a functional neural phenotype that characterizes individuals who are prone to show exaggerated cardiovascular reactivity...
  83. pmc Depressive symptoms during the menopausal transition: the Study of Women's Health Across the Nation (SWAN)
    Joyce T Bromberger
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States
    J Affect Disord 103:267-72. 2007
    ..This study examined the longitudinal relationship between changes in menopausal status and the risk of clinically relevant depressive symptoms and whether the relationship differed according to initial depressive symptom level...
  84. pmc Unfair treatment and trait anger in relation to nighttime ambulatory blood pressure in African American and white adolescents
    Danielle L Beatty
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Psychosom Med 71:813-20. 2009
    ....
  85. ncbi request reprint Social networks and marital status predict mortality in older women: prospective evidence from the Study of Osteoporotic Fractures (SOF)
    Thomas Rutledge
    Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Psychosom Med 65:688-94. 2003
    ..To assess the relationship between social network size and prospective mortality risk among a large sample of older, Caucasian women...
  86. pmc Racial differences in perception of healthy body weight in midlife women: results from the Do Stage Transitions Result in Detectable Effects study
    Semara Thomas
    Department of Obstetrics and Gynecology, University of Virginia, Charlottesville, VA, USA
    Menopause 20:269-73. 2013
    ..Midlife is a critical period for women that typically includes weight gain. We assessed the associations between perception of healthy body weight and body mass index (BMI) and whether they vary by race...
  87. ncbi request reprint Helping midlife women predict the onset of the final menses: SWAN, the Study of Women's Health Across the Nation
    Nanette Santoro
    Department of Obstetrics, Gynecology and Women s Health, Albert Einstein College of Medicine, New York, NY 10461, USA
    Menopause 14:415-24. 2007
    ..Women approaching menopause often ask their doctors, "When are my periods going to end?" The objective of this study was to predict time to the final menstrual period (FMP)...
  88. ncbi request reprint Ethnic differences in past hysterectomy for benign conditions
    Lynda H Powell
    Department of Preventive Medicine, Rush Presbyterian St Luke s Medical Center, Chicago, IL, USA
    Womens Health Issues 15:179-86. 2005
    ..Hysterectomy for a benign condition is common, particularly in the underserved. The objective was to determine if ethnic differences could be explained by known risk factors...
  89. ncbi request reprint Increases in job strain are associated with incident hypertension in the CARDIA Study
    Jerome H Markovitz
    Division of Preventive Medicine, University of Alabama at Birmingham, USA
    Ann Behav Med 28:4-9. 2004
    ..Job strain, defined as high job demands and low decision latitude, has been associated with increased blood pressure levels in some studies, but most of these studies have been cross-sectional...
  90. ncbi request reprint Socioeconomic status and health in adolescents: the role of stress interpretations
    Edith Chen
    Department of Psychology, University of British Columbia, Vancouver, Canada
    Child Dev 75:1039-52. 2004
    ..Results suggest that the larger social environment helps explain how adolescents approach new social situations, which in turn has implications for adolescent physical health...
  91. ncbi request reprint Prenatal and early childhood blood lead levels and cardiovascular functioning in 9(1/2) year old children
    Brooks B Gump
    State University of New York College at Oswego, NY 13126, USA
    Neurotoxicol Teratol 27:655-65. 2005
    ..Finally, these effects were significant for lead levels considered low, notably, below the 10 microg/dL threshold currently adopted by the CDC for deleterious effects...
  92. ncbi request reprint Cardiovascular reactivity to work stress predicts subsequent onset of hypertension: the Air Traffic Controller Health Change Study
    Eileen E Ming
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Psychosom Med 66:459-65. 2004
    ..The hypothesis that increased blood pressure reactivity to stress is an early risk marker of hypertension was tested in a 1994 follow-up of the 1974 to 1978 Air Traffic Controller Health Change Study sample...
  93. ncbi request reprint Trait anger and the metabolic syndrome predict progression of carotid atherosclerosis in healthy middle-aged women
    K Raikkonen
    University of Helsinki, Department of Psychology, Helsinki, Finland
    Psychosom Med 66:903-8. 2004
    ..We tested to see if high levels of the attitudinal and emotional aspects of hostility lead to progression of carotid atherosclerosis in women and if the metabolic syndrome is a mediator of the association...
  94. ncbi request reprint Social networks are associated with lower mortality rates among women with suspected coronary disease: the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation study
    Thomas Rutledge
    University of California, San Diego, San Diego, California, USA
    Psychosom Med 66:882-8. 2004
    ..To examine the association between social relationships measured by the Social Network Scale and coronary artery disease (CAD) risk and mortality among a sample of women with suspected CAD...
  95. ncbi request reprint Depressive symptoms, insulin resistance, and risk of diabetes in women at midlife
    Susan A Everson-Rose
    Department of Preventive Medicine, Rush University Medical Center, 1700 W Van Buren St, Suite 470, Chicago, IL 60612, USA
    Diabetes Care 27:2856-62. 2004
    ..To examine depression and 3-year change in insulin resistance and risk of diabetes and whether associations vary by race...
  96. ncbi request reprint Physiologic markers of chronic stress in premenopausal, middle-aged women
    Lynda H Powell
    Department of Preventive Medicine, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, USA
    Psychosom Med 64:502-9. 2002
    ..The purpose of this study was to identify physiological markers of chronic stress in middle-aged women that can be assessed simply and are thus feasible for introduction into large-scale, epidemiologic studies of aging...
  97. ncbi request reprint Causes and demographic, medical, lifestyle and psychosocial predictors of premature mortality: the CARDIA study
    Carlos Iribarren
    Division of Research, Kaiser Permanente, Oakland, CA, USA
    Soc Sci Med 60:471-82. 2005
    ....
  98. ncbi request reprint Physical activity and changes in weight and waist circumference in midlife women: findings from the Study of Women's Health Across the Nation
    Barbara Sternfeld
    Division of Research, Kaiser Permanente, Oakland, CA 94611, USA
    Am J Epidemiol 160:912-22. 2004
    ....
  99. ncbi request reprint Hemostatic factors and estrogen during the menopausal transition
    MaryFran R Sowers
    Department of Epidemiology, University of Michigan School of Public Health, 339 East Liberty Street, Suite 310, Ann Arbor, Michigan 48104, USA
    J Clin Endocrinol Metab 90:5942-8. 2005
    ..Therefore, we evaluated endogenous hormone concentrations, menopause transition stages, and adoption of exogenous hormone use in relation to hemostatic and inflammation marker concentrations in women...
  100. ncbi request reprint Cardiovascular reactivity during social and nonsocial stressors: do children's personal goals and expressive skills matter?
    Edith Chen
    Department of Psychology, Washington University, St Louis, Missouri 63130, USA
    Health Psychol 21:16-24. 2002
    ..Personal strivings and expressive skills do matter for understanding cardiovascular responses in children...
  101. ncbi request reprint The relationship of longitudinal change in reproductive hormones and vasomotor symptoms during the menopausal transition
    John F Randolph
    L4228 Women s Hospital, University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, Michigan 48109 0276, USA
    J Clin Endocrinol Metab 90:6106-12. 2005
    ..Vasomotor symptoms are reported by 65-76% of women traversing the menopausal transition and are a primary reason for medical intervention during this life stage...

Research Grants39

  1. ANTECEDENTS OF THE TYPE A BEHAVIOR PATTERN
    Karen Matthews; Fiscal Year: 2006
    ..This project will contribute to the knowledge base necessary to prevent the early development of sub clinical CVD. ..
  2. Womens Health Across the Nation
    Karen Matthews; Fiscal Year: 2007
    ..With SWAN III, many of the original goals of SWAN will be brought to fruition. We will build upon the rich foundation developed during SWAN I and II and link these data to important menopause-related and health outcomes in SWAN III. ..
  3. CARDIOVASCULAR BEHAVIORAL MEDICINE RESEARCH TRAINING
    Karen Matthews; Fiscal Year: 2007
    ..Support is requested for five postdoctoral, five predoctoral, and two short-term summer trainees. ..
  4. Stress, Sleep and Emerging CVD Risk Factors
    Karen Matthews; Fiscal Year: 2007
    ..The study will provide novel data testing the relationships of daytime stressful events, SDB, and other nocturnal physiological measures with the emerging risk factors and subclinical CVD measured in HeartSCORE. ..
  5. Pittsburgh Mind-Body Center-II Summer Institutes
    Karen Matthews; Fiscal Year: 2007
    ..We anticipate that 30 scientists will attend the Summer Institute each year, with 20 from outside Western Pennsylvania. ..
  6. Development of Psychobiological Risk Factors in Adolescence
    Karen Matthews; Fiscal Year: 2009
    ..The research has the potential of understanding the basis of adolescent health disparities. ..
  7. ANTECEDENTS OF THE TYPE A BEHAVIOR PATTERN
    Karen Matthews; Fiscal Year: 2002
    ..abstract_text> ..
  8. ANTECEDENTS OF THE TYPE A BEHAVIOR PATTERN
    Karen Matthews; Fiscal Year: 1991
    ....
  9. ANTECEDENTS OF THE TYPE A BEHAVIOR BEHAVIOR PATTERN
    Karen Matthews; Fiscal Year: 1993
    ..The proposed project attempts to add significantly to the understanding of etiology of Black-White and social class differences in cardiovascular risk factors, and the role of hostility in this development...
  10. Development of Psychobiological Risk Factors in Adolescence
    Karen A Matthews; Fiscal Year: 2010
    ..The research has the potential of understanding the basis of adolescent health disparities. ..