Research Topics
| William H MatthaiSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Detail Information
Publications
Evaluation of thrombocytopenia in the acute coronary syndromeWilliam H Matthai
Department of Medicine, University of Pennsylvania Medical School, Philadelphia, Pennsylvania 19104, USA
Curr Opin Hematol 17:398-404. 2010..Treatment strategies, both medical and mechanical, may cause thrombocytopenia. This review will introduce a differential diagnosis, diagnostic strategies, and treatment options for patients with an acute coronary syndrome...
Safety and efficacy of argatroban in patients with heparin-induced thrombocytopeniaWilliam H Matthai
University of Pennsylvania Medical School, Penn Presbyterian Medical Center, Philadelphia, PA 19104, USA
Curr Hematol Rep 5:95-9. 2006..There is somewhat limited experience with its use in a number of other clinical scenarios in these patients. The current data on the use of argatroban in patients with HIT are reviewed...
Treatment of heparin-induced thrombocytopenia in cardiovascular patientsWilliam H Matthai
Penn Presbyterian Medical Center, WS 392, Philadelphia, PA 19104, USA
Expert Opin Pharmacother 7:267-76. 2006..These agents and their use in cardiac patients, including patients with acute coronary syndrome, percutaneous coronary interventions, acute ST elevation myocardial infarction or cardiac surgery, will be reviewed...
Thrombocytopenia in cardiovascular patients: diagnosis and managementWilliam H Matthai
University of Pennsylvania Medical Center Presbyterian, 39th and Market St, Philadelphia, PA 19104, USA
Chest 127:46S-52S. 2005..The use of a direct thrombin inhibitor in treatment should be considered early if a diagnosis of heparin-induced thrombocytopenia is possible...
Argatroban anticoagulation in patients with a history of heparin-induced thrombocytopeniaWilliam H Matthai
University of Pennsylvania Medical School, 39th and Market Sts WS 392, Philadelphia, PA 10104, USA
Thromb Res 116:121-6. 2005..We evaluated the safety and efficacy of argatroban, a direct thrombin inhibitor, as an anticoagulant in patients with a history of HIT needing acute anticoagulation...
Evaluating the etiology of mechanical valve obstruction: use of clinical parameters, fluoroscopy, and echocardiographyAnthony Licata
Division of Cardiovascular Medicine, University of Pennsylvania Medical School, Philadelphia, Pennsylvania 19104, USA
Catheter Cardiovasc Interv 55:495-500. 2002..Clinical evaluation and diagnostic evaluation with fluoroscopy and echocardiography in distinguishing pannus from thrombus are reviewed...
Effective management of acute coronary thrombosis in a young woman with lupus using aggressive medical therapyParin J Patel
Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Cardiology 118:45-9. 2011..Assessing clinical risk factors and using technologies such as intravascular ultrasound can help make the correct treatment decision...
One-year clinical outcomes of protected and unprotected left main coronary artery stentingMichael P Kelley
Hospital of the University of Pennsylvania, University Health System, 9 Gates, 3400 Spruce Street, Philadelphia, PA 19104, USA
Eur Heart J 24:1554-9. 2003..Stenting for unprotected LMCA disease in a high-risk population should only be considered in the absence of other revascularization options. Further studies are needed to evaluate the role of stenting for unprotected LMCA disease...
Argatroban anticoagulation during percutaneous coronary intervention in patients with heparin-induced thrombocytopeniaBruce E Lewis
Loyola University Medical Center, Maywood, Illinois, USA
Catheter Cardiovasc Interv 57:177-84. 2002..Overall, outcomes were comparable with those historically reported for heparin. Argatroban therefore is a reasonable anticoagulant option in this setting, where current options are limited...
Argatroban anticoagulation in conjunction with glycoprotein IIb/IIIa inhibition in patients undergoing percutaneous coronary intervention: an open-label, nonrandomized pilot studyIk Kyung Jang
Cardiology Division, Gray Bigelow 800, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
J Thromb Thrombolysis 18:31-7. 2004..This multicenter, prospective pilot study evaluated the efficacy and safety of argatroban in combination with glycoprotein IIb/IIIa inhibition in patients undergoing percutaneous coronary intervention...
Role of cardiac troponin T in the long-term risk stratification of patients undergoing percutaneous coronary interventionJorge R Kizer
Division of Cardiology, Department of Medicine and Public Health, Weill Medical College of Cornell University, New York, NY, USA
Eur Heart J 24:1314-22. 2003..Whether the prognostic significance of smaller post-procedural TnT elevations extends beyond the intermediate-term awaits further investigation...
