Affiliation: University of Wisconsin
- Intrathecal triple therapy decreases central nervous system relapse but fails to improve event-free survival when compared with intrathecal methotrexate: results of the Children's Cancer Group (CCG) 1952 study for standard-risk acute lymphoblastic leukemiYousif Matloub
Department of Pediatrics, University of Wisconsin Children s Hospital, Madison, WI 53792 4108, USA
Blood 108:1165-73. 2006..3% +/- 1.5% versus 94.4% +/- 1.1% for IT MTX (P = .01). It appears that ITT improves presymptomatic CNS treatment but does not improve overall outcome...