- Substrate specificity of schistosome versus human legumain determined by P1-P3 peptide librariesMary A Mathieu
Department of Pathology, UCSF, San Francisco, CA 94143, USA
Mol Biochem Parasitol 121:99-105. 2002..Predictions of substrate specificity from the library screen were confirmed using single peptide substrates for kinetic assays...
- Functional expression and characterization of Schistosoma mansoni cathepsin B and its trans-activation by an endogenous asparaginyl endopeptidaseMohammed Sajid
Department of Pathology, Tropical Disease Research Unit and Sandler Centre for Basic Research in Parasitic Diseases, University of California San Francisco, Box 0511, San Francisco, CA 94143, USA
Mol Biochem Parasitol 131:65-75. 2003..This study characterizes the major digestive cysteine peptidase in schistosomes and defines novel trans-processing events required to activate the SmCB1 zymogen in vitro which may facilitate the digestive process in vivo...