Frederick A Masoudi

..The objective of this study was to examine the association between diabetes and patients' health status outcomes one year after an acute coronary syndrome (ACS)...

..Our objectives were to assess the correlates of ACE inhibitor use and the relationship between ACE inhibitor prescription and mortality in older patients with heart failure...

..We sought to determine patterns of aspirin use and the relationship between aspirin prescription and outcomes in patients with coronary artery disease (CAD) and heart failure (HF)...

..Little is known, however, about the complexity and financial burden of medical therapy in this population...

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..Long-term trends in the clinical characteristics, quality of care, and outcomes for AMI over time from the health system perspective in geographically diverse populations are not well known...

..Whether this results in adverse outcomes is unknown...

..Our goal was to assess the prevalence of the failure to identify high-risk ECG findings in ED patients with AMI and to determine whether this failure is associated with lower-quality care...

..This review highlights the importance of heart failure in the older population and identifies the specific areas where research and policy initiatives may be instrumental in reducing the impact of the condition...

..Our objective was to determine the proportion of older persons meeting enrollment criteria of randomized controlled trials of agents that prolong life in heart failure...

..This study was designed to determine if women are more likely than men to have heart failure (HF) with preserved systolic function after adjustment for potential confounders, including age...

..This article reviews the epidemiology of HF and diabetes, the mechanisms whereby diabetes causes HF, and the pharmacotherapy of both HF and diabetes. Specific challenges in treating patients with both HF and diabetes are also addressed...

..We studied the adoption of spironolactone therapy after publication of the Randomized Aldactone Evaluation Study (RALES) in national cohorts of older patients hospitalized for heart failure...

..Little is known about the effect of nonadherence among patients with coronary artery disease (CAD) on a broad spectrum of outcomes including cardiovascular mortality, cardiovascular hospitalizations, and revascularization procedures...

..We assessed the independent relationship between age and the quality of medical care provided to patients presenting to the emergency department (ED) with acute myocardial infarction...

..The extent to which this reflects higher rates of contraindications in patients with higher risk or larger gaps in care quality has not been explored...

..Our objectives were to characterize patterns of change in Hb over time in patients with HF and to evaluate the relationship between longitudinal measures of Hb and adverse outcomes...

..Our objective was to derive and validate a risk score for in-hospital mortality in patients hospitalized with heart failure using American Heart Association Get With the Guidelines-Heart Failure (GWTG-HF) program data...

..These findings highlight the need to investigate why patients with uncontrolled BP do not receive treatment intensification...

..Clinical practice guidelines recommend multiple cardioprotective medications to reduce recurrent events. We evaluated the association between cardioprotective medication adherence and mortality among patients with diabetes and IHD...

..Further studies to establish the safety and effectiveness of this practice are needed to ensure optimal care of patients with diabetes and heart failure...

..Early outpatient follow-up after acute myocardial infarction (AMI) is recommended in guidelines, but its relationship with the use of evidence-based therapies is unknown...

..Older age is a risk factor for higher mortality after acute myocardial infarction (AMI), but the association with health status outcomes is largely unexplored...

..Controversy remains regarding whether gender differences exist in clinical management after exercise treadmill testing (ETT)...

..However, little is known about their prognostic use in combination and in addition to the Duke Treadmill Score (DTS)...

..These results underscore the importance of treatments aimed at maintaining functional status in older persons with heart failure, including those with significant baseline functional limitations...

..Preoperative patient self-report of health status may be particularly useful in refining risk stratification and informing decision-making before and following cardiac surgery in older patients...

..Despite a recent American Heart Association (AHA) consensus statement emphasizing the importance of resistant hypertension, the incidence and prognosis of this condition are largely unknown...

..The current use of dual-chamber ICDs is not well characterized...

..We assessed the degree to which differences in guideline-based medical therapy for acute myocardial infarction (AMI) contribute to the higher mortality associated with kidney disease...

..The objective of this study was to identify the factors associated with the development of depressive symptoms in outpatients with heart failure (HF)...

..This suggests that these measures may assess different aspects of heart failure severity, and that physiologic measures do not reflect patients' perceptions of the impact of heart failure on their health status...

..We therefore sought to determine the extent to which provider and hospital characteristics contribute to small-area geographic variation in heart failure care after controlling for patient factors...

..We examined the frequency of this practice and evaluated the associated outcomes of readmission and mortality...

..This association appears to be explained, in part, by coexistent depression. Future studies should evaluate interventions such as depression treatment to improve medication adherence and health status...

..In particular, those who are foreign-born and who do not speak English as their primary language may have greater challenges interacting with the health care system and thus be at greater risk for adverse outcomes...

..Limited literature exists on the association between medication adherence and outcomes among patients with heart failure...

..We hypothesized that women who undergo primary prevention ICD implantation more often meet strict trial enrollment criteria for this therapy...

..Patient satisfaction is increasingly recognized as a quality indicator and important outcome of care. Little is known about the clinical factors associated with satisfaction after myocardial infarction (MI)...

..Left ventricular hypertrophy is a major independent risk factor for cardiovascular mortality. The contribution of left ventricular hypertrophy to racial and ethnic differences in cardiovascular mortality is poorly understood...

..Our objective was to determine the prognostic importance of exercise capacity for nonfatal cardiac events in a clinical population...

..Our objective was to compare rates of in-hospital adverse events in men and women receiving implantable cardioverter- defibrillator (ICD) therapy in community practice...

..Ethnic minorities are at proportionately greater risk for developing extracoronary vascular disease including heart failure and cerebrovascular disease...

..Our objective was to evaluate use of beta-blockers (BB) among patients with heart failure undergoing a cardiac device procedure...

..Despite the importance of blood pressure (BP) control in secondary prevention, a significant proportion of patients with coronary disease have uncontrolled BP...

..Accordingly, we compared rates of hypertension control between women and men as a function of age...

..Medication nonadherence may reduce the effectiveness of therapies. To our knowledge, the association between medication nonadherence and mortality remains unexplored outside the context of clinical trials...

..Little is known about the effects of low health literacy among patients with heart failure, a condition that requires self-management and frequent interactions with the health care system...

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..Electrocardiographic criteria for the diagnosis of left ventricular hypertrophy in current use were defined using autopsy results or echocardiography; criteria defined using mortality might be more clinically meaningful...

..However, patterns and safety of β-blocker intensification in routine practice are poorly described...

..The impact of inpatient and follow-up cardiology care on patient outcomes after acute coronary syndrome (ACS) hospital discharge is unknown...

..The purpose of this study was to assess whether depressive symptoms are independently associated with changes in heart failure (HF)-specific health status...

..This approach will require a rationally designed health care delivery system that applies the best available evidence to the care of individual patients with heart failure...

..Acute kidney injury (AKI) is a common complication during hospitalization and is an accepted risk factor for in-hospital mortality. However, the association of severity of AKI with the long-term risk of death is not well defined...

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..It is anticipated that these results will have an impact on physician decision making and patient education regarding expected benefits from revascularization and will help guide future research...

..After 3 years of experience with the National Heart Failure project, it is appropriate to highlight the issues pertinent to future quality improvement initiatives in heart failure care...

..Although implantable cardioverter-defibrillators (ICDs) reduce mortality in selected patients, they are also associated with potential risks. Periprocedural decision making requires understanding both benefits and risks...

..The objective of this study was to determine the importance of chest pain during ETT in predicting future nonfatal cardiac hospitalizations...

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..The goal of this study was to determine if cardiology subspecialty involvement improves the attainment of recommended low-density lipoprotein (LDL) cholesterol and blood pressure (BP) targets in coronary artery disease (CAD) patients...

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..This care is complementary to contemporary heart failure care and can be provided concurrently at any point during the illness based on patient and caregiver needs...

..Weight loss is recommended among overweight survivors of myocardial infarction (MI). This study describes patterns of weight change among overweight patients with MI and identifies factors associated with weight change...

..We sought to evaluate the prevalence of acute, severe, noncardiac conditions present at the time of hospital admission with acute myocardial infarction and to assess the association of these conditions with in-hospital mortality...

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..Prior studies have reported conflicting findings concerning the association of socioeconomic status (SES), treatment, and outcomes in patients hospitalized with heart failure (HF)...

..Little is known regarding the use of secondary prevention in older patients undergoing CABG during hospitalization for acute myocardial infarction (AMI)...

..We examine the implications of these findings for the millions of vulnerable Americans who rely on safety-net hospitals for their care...

..Distinct morbidity and mortality burdens in black versus white patients underscore the importance of improving patient risk-stratification, defining optimal therapies, and exploring physiological underpinnings of racial differences...

..CONCLUSIONS: There were small sex differences in the quality of care provided to fee-for-service Medicare patients hospitalized with heart failure, although women had higher rates of survival than men up to 1 year after hospitalization...

..We sought to describe a contemporary national sample of elderly patients with HF and to examine the sample for age-related trends in clinical characteristics...

..Whether metrics that incorporate multiple glucose assessments during acute myocardial infarction hospitalization are better predictors of mortality than admission glucose alone is not well defined...

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..Our objective was to evaluate the association between statin use and survival among a national sample of elderly patients hospitalized with HF...

..It is anticipated that these results will have a significant impact on physician decision making and performance, reimbursement policy, and will help guide future research...

..Associations with estimated GFR demonstrated similar trends. In conclusion, renal function in hospitalized patients with AMI is an important and consistent predictor of mortality for up to 10 yr...

..Several patient characteristics, including age and sex, were associated with the use of specialty care, suggesting that factors other than clinical presentation may independently influence the use of specialty care...

..We tested the hypothesis that one health status measure, the Kansas City Cardiomyopathy Questionnaire (KCCQ), provides prognostic information independent of other clinical data in outpatients with heart failure (HF)...

..3%, P = .98). CONCLUSION: Patients with heart failure who are hospitalized in the United States had lower short-term mortality at 30 days, but 1-year mortality rates were not significantly different between the United States and Canada...

..97). CONCLUSIONS: Heart failure with preserved EF confers a considerable burden on patients, with the risk of readmission, disability, and symptoms subsequent to hospital discharge, comparable to that of HF patients with depressed EF...

..The aim of the study was to assess the quality of care between male and female emergency department (ED) patients with acute myocardial infarction (AMI)...

..These findings suggest that anemia may be predominantly a marker rather than a mediator of increased mortality risk in older patients with HF...

..To characterize the relationship between hydroxymethylglutaryl-CoA reductase inhibitors (statins) and outcomes in older persons with acute myocardial infarction (AMI)...

..We sought to determine the impact of these insulin sensitizers on outcomes in diabetic patients after hospitalization with acute myocardial infarction (AMI)...

..86, 95% CI 1.45 to 2.41), weekly (OR 4.24, 95% CI 3.09 to 5.82), and daily (OR 6.12, 95% CI 3.62 to 10.3) were more likely to have AP 1 month later. In conclusion, > 1 in 4 patients reported AP 1 month after an MI...

..CONCLUSIONS: Elevated glucose is common, rarely treated, and associated with increased mortality risk in elderly acute myocardial infarction patients, particularly those without recognized diabetes...

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