Gertraud Maskarinec

Summary

Affiliation: University of Hawaii
Country: USA

Publications

  1. pmc Mammographic Density and Matrix Metalloproteinases in Breast Tissue
    Jana S Steude
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI, 96813, USA
    Cancer Microenviron . 2009
  2. pmc Epidemiologic studies of isoflavones & mammographic density
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Nutrients 2:35-48. 2010
  3. pmc Percentage density, Wolfe's and Tabár's mammographic patterns: agreement and association with risk factors for breast cancer
    Inger T Gram
    Institute of Community Medicine, University of Tromsø, Breivika, Norway
    Breast Cancer Res 7:R854-61. 2005
  4. pmc The association of mammographic density with ductal carcinoma in situ of the breast: the Multiethnic Cohort
    Jasmeet K Gill
    Cancer Research Center of Hawaii, Honolulu, Hawaii, USA
    Breast Cancer Res 8:R30. 2006
  5. pmc Time dependent ethnic convergence in colorectal cancer survival in Hawaii
    Ian S Pagano
    Cancer Research Center of Hawai i, University of Hawai i, Lauhala Street, Honolulu, HI, USA
    BMC Cancer 3:5. 2003
  6. pmc Mammographic density and epithelial histopathologic markers
    Martijn Verheus
    Cancer Research Center, University of Hawaii, Honolulu, HI, USA
    BMC Cancer 9:182. 2009
  7. pmc Breast density and polymorphisms in genes coding for CYP1A2 and COMT: the Multiethnic Cohort
    Yumie Takata
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI, USA
    BMC Cancer 7:30. 2007
  8. pmc Comparison of breast density measured by dual energy X-ray absorptiometry with mammographic density among adult women in Hawaii
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala St, Honolulu, HI 96813, USA
    Cancer Epidemiol 35:188-93. 2011
  9. ncbi request reprint IGF-I and mammographic density in four geographic locations: a pooled analysis
    Gertraud Maskarinec
    Cancer Research Center, University of Hawaii, Honolulu, HI 96813, USA
    Int J Cancer 121:1786-92. 2007
  10. ncbi request reprint Alcohol and dietary fibre intakes affect circulating sex hormones among premenopausal women
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Public Health Nutr 9:875-81. 2006

Research Grants

  1. Effects of Soy on Estrogens in Breast Fluid and Urine
    Gertraud Maskarinec; Fiscal Year: 2007
  2. Nutritional Risk Factors for Type 2 Diabetes in the Multiethnic Cohort
    Gertraud Maskarinec; Fiscal Year: 2007
  3. Inflammatory Markers in a 2-Year Soy Intervention among Premenopausal Women
    Gertraud Maskarinec; Fiscal Year: 2007
  4. Effects of Soy on Estrogens in Breast Fluid and Urine
    Gertraud Maskarinec; Fiscal Year: 2009
  5. Cancer Control Research Training in Multiethnic Hawaii
    Gertraud Maskarinec; Fiscal Year: 2007
  6. Soy Consumption and Breast Tissue Proliferation
    Gertraud Maskarinec; Fiscal Year: 2006
  7. NESTED CASE CONTROL STUDY OF MAMMOGRAPHIC DENSITY
    Gertraud Maskarinec; Fiscal Year: 2002
  8. Breast Density, IGF-I, & Prolactin, in Four Populations
    Gertraud Maskarinec; Fiscal Year: 2004
  9. Effects of Soy on Estrogens in Breast Fluid and Urine
    Gertraud Maskarinec; Fiscal Year: 2010

Detail Information

Publications105 found, 100 shown here

  1. pmc Mammographic Density and Matrix Metalloproteinases in Breast Tissue
    Jana S Steude
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI, 96813, USA
    Cancer Microenviron . 2009
    ..However, future investigations into activities and ratios of additional proteases and their inhibitors as well as other pathways, such as inflammation, are needed...
  2. pmc Epidemiologic studies of isoflavones & mammographic density
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Nutrients 2:35-48. 2010
    ..Soy foods and isoflavone supplements within a nutritional range do not appear to modify breast cancer risk as assessed by mammographic density...
  3. pmc Percentage density, Wolfe's and Tabár's mammographic patterns: agreement and association with risk factors for breast cancer
    Inger T Gram
    Institute of Community Medicine, University of Tromsø, Breivika, Norway
    Breast Cancer Res 7:R854-61. 2005
    ..The purpose of this report was to classify mammograms according to four methods and to examine their agreement and their relationship to selected risk factors for breast cancer...
  4. pmc The association of mammographic density with ductal carcinoma in situ of the breast: the Multiethnic Cohort
    Jasmeet K Gill
    Cancer Research Center of Hawaii, Honolulu, Hawaii, USA
    Breast Cancer Res 8:R30. 2006
    ..However, little research has been done on mammographic density and ductal carcinoma in situ (DCIS) of the breast, which is thought to be a precursor lesion to some invasive breast cancers...
  5. pmc Time dependent ethnic convergence in colorectal cancer survival in Hawaii
    Ian S Pagano
    Cancer Research Center of Hawai i, University of Hawai i, Lauhala Street, Honolulu, HI, USA
    BMC Cancer 3:5. 2003
    ..We examined the hypothesis that improved cancer screening across all ethnic groups will reduce ethnic differences in colorectal cancer survival...
  6. pmc Mammographic density and epithelial histopathologic markers
    Martijn Verheus
    Cancer Research Center, University of Hawaii, Honolulu, HI, USA
    BMC Cancer 9:182. 2009
    ..We explored the association of mammographic density, a breast cancer risk factor, with hormonal and proliferation markers in benign tissue from tumor blocks of pre-and postmenopausal breast cancer cases...
  7. pmc Breast density and polymorphisms in genes coding for CYP1A2 and COMT: the Multiethnic Cohort
    Yumie Takata
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI, USA
    BMC Cancer 7:30. 2007
    ..This cross-sectional analysis examined the relation between mammographic density and the CYP1A2*1F and COMT Val58 Met polymorphisms among 332 breast cancer cases and 254 controls in the Hawaii component of the Multiethnic Cohort...
  8. pmc Comparison of breast density measured by dual energy X-ray absorptiometry with mammographic density among adult women in Hawaii
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala St, Honolulu, HI 96813, USA
    Cancer Epidemiol 35:188-93. 2011
    ..While use of mammography is limited, due to concerns related to radiation exposure, dual energy X-ray absorptiometry (DXA), commonly available in medical care settings, is characterized by low radiation exposure...
  9. ncbi request reprint IGF-I and mammographic density in four geographic locations: a pooled analysis
    Gertraud Maskarinec
    Cancer Research Center, University of Hawaii, Honolulu, HI 96813, USA
    Int J Cancer 121:1786-92. 2007
    ..Based on this analysis, the influence of circulating levels of IGF-I, IGFBP-3, and prolactin on percent density appears to be very small...
  10. ncbi request reprint Alcohol and dietary fibre intakes affect circulating sex hormones among premenopausal women
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Public Health Nutr 9:875-81. 2006
    ..The association of alcohol and fibre intake with breast cancer may be mediated by circulating sex hormone levels, which are predictors of breast cancer risk...
  11. ncbi request reprint Ethnic and geographic differences in mammographic density and their association with breast cancer incidence
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Breast Cancer Res Treat 104:47-56. 2007
    ..This comparison of mammographic densities suggests that, on a group level, age-adjusted dense areas may reflect breast cancer incidence better than percent densities...
  12. ncbi request reprint Urinary isoflavonoid excretion and soy consumption in three generations of Japanese women in Hawaii
    G Maskarinec
    Cancer Research Center of Hawaii, Honolulu, HI 96813, USA
    Eur J Clin Nutr 61:255-61. 2007
    ....
  13. ncbi request reprint Serum prostate-specific antigen but not testosterone levels decrease in a randomized soy intervention among men
    G Maskarinec
    Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA
    Eur J Clin Nutr 60:1423-9. 2006
    ..The goal of this pilot study was to evaluate the feasibility of a randomized, crossover soy trial among men and to investigate the effects of daily soy intake on serum prostate-specific antigen (PSA) and testosterone levels...
  14. ncbi request reprint Trends of breast cancer incidence and risk factor prevalence over 25 years
    Gertraud Maskarinec
    Cancer Research Center, Honolulu, HI 96813, USA
    Breast Cancer Res Treat 98:45-55. 2006
    ..To examine the trends in the prevalence of breast cancer risk factors in relation to breast cancer incidence trends and to explore whether the changes in risk factors differed by ethnicity in Hawaii over a 25-year period...
  15. ncbi request reprint Trends and dietary determinants of overweight and obesity in a multiethnic population
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, 96813, USA
    Obesity (Silver Spring) 14:717-26. 2006
    ..To describe trends in BMI among different ethnic groups in Hawaii and to explore the relation of nutrient and food intake with excess weight...
  16. ncbi request reprint A longitudinal investigation of mammographic density: the multiethnic cohort
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, 96813, USA
    Cancer Epidemiol Biomarkers Prev 15:732-9. 2006
    ..Risk factors that influence the decline in mammographic densities over time may be important for breast cancer prevention because cumulative percent densities may reflect the age-related increase in breast cancer risk...
  17. ncbi request reprint Mortality and cancer incidence among children and adolescents in Hawaii 20 years after a heptachlor contamination episode
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    J Environ Pathol Toxicol Oncol 24:235-49. 2005
    ..Overall, this report found no indication of higher mortality or cancer incidence among children born during the heptachlor contamination period...
  18. ncbi request reprint Alcohol consumption and mammographic density in a multiethnic population
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA
    Int J Cancer 118:2579-83. 2006
    ..The larger difference in some subgroups suggests that women with certain characteristics may be more susceptible to the influence of alcohol on breast density than others...
  19. ncbi request reprint Soy foods for breast cancer survivors and women at high risk for breast cancer?
    Gertraud Maskarinec
    Cancer Etiology Program, Cancer Research Center of Hawaii, Honolulu 96813, USA
    J Am Diet Assoc 105:1524-8. 2005
  20. ncbi request reprint Insulin-like growth factor-1 and binding protein-3 in a 2-year soya intervention among premenopausal women
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Br J Nutr 94:362-7. 2005
    ..Adding soya foods to the diet of premenopausal women does not appear to lower serum levels of IGF-1 and IGFBP-3; if anything, the greater protein intake from soya may lead to a small increase in IGF-1 serum levels...
  21. ncbi request reprint Nonsteroidal anti-inflammatory drugs (NSAIDs) and mammographic density
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Breast Cancer Res Treat 112:133-9. 2008
    ..Experimental studies need to be performed to study the effect, if any, of NSAID use on breast density...
  22. ncbi request reprint Lifestyle risk factors for chronic disease in a multiethnic population: an analysis of two prospective studies over a 20-year period
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, HI 96813, USA
    Ethn Dis 17:597-603. 2007
    ..This study investigated changes in risk factors in Hawaii over 20 years and compared health behaviors among ethnic groups with well-documented differences in disease risk...
  23. pmc Mammographic density as a predictor of breast cancer outcome
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, University of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Future Oncol 6:351-4. 2010
    ..Future studies that incorporate additional risk factors, such as obesity, need to examine the role of mammographic density in larger patient populations before including breast density in treatment decision models...
  24. pmc Factors affecting survival among women with breast cancer in Hawaii
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii 96813, USA
    J Womens Health (Larchmt) 20:231-7. 2011
    ....
  25. pmc The relation of leptin and adiponectin with breast density among premenopausal women
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, Hawaii 96813, USA
    Eur J Cancer Prev 19:55-60. 2010
    ..In contrast, the findings suggest the possibility that the inverse association of BMI with breast cancer risk in premenopausal women is mediated by adipocytokines...
  26. pmc Soy consumption and histopathologic markers in breast tissue using tissue microarrays
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, Hawaii 96813, USA
    Nutr Cancer 61:708-16. 2009
    ..The results of this investigation provide some assurance that soy intake does not adversely affect markers of proliferation. TMAs were shown to be a useful tool for epidemiologic research...
  27. doi request reprint Cancer protective properties of cocoa: a review of the epidemiologic evidence
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, Hawaii, USA
    Nutr Cancer 61:573-9. 2009
    ....
  28. pmc Inflammatory markers in a 2-year soy intervention among premenopausal women
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Suite 510, 1236 Lauhala Street, Honolulu, Hawai i 96813, USA
    J Inflamm (Lond) 6:9. 2009
    ..Epidemiologic evidence supports a role of soy foods in breast cancer etiology. Because chronic inflammation appears to be a critical component in carcinogenesis, we examined the potential anti-inflammatory effects of soy foods...
  29. pmc Diabetes prevalence and body mass index differ by ethnicity: the Multiethnic Cohort
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala St, Honolulu, HI 96813, USA
    Ethn Dis 19:49-55. 2009
    ..The objectives of this study were to estimate the prevalence of diabetes among participants of the Multiethnic Cohort (MEC) and to examine the association of body mass index (BMI) with self-reported diabetes by ethnicity...
  30. pmc Various doses of soy isoflavones do not modify mammographic density in postmenopausal women
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, HI 96813, USA
    J Nutr 139:981-6. 2009
    ..In this randomized 2-y trial, isoflavone supplements did not modify breast density in postmenopausal women. These findings offer reassurance that isoflavones do not act like hormone replacement medication on breast density...
  31. pmc Diabetes incidence based on linkages with health plans: the multiethnic cohort
    Gertraud Maskarinec
    Cancer Research Center, University of Hawaii, Honolulu, Hawaii, USA
    Diabetes 58:1732-8. 2009
    ..Using the Hawaii component of the Multiethnic Cohort (MEC), we estimated diabetes incidence among Caucasians, Japanese Americans, and Native Hawaiians...
  32. doi request reprint Inflammatory markers in a randomised soya intervention among men
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, HI, USA
    Br J Nutr 101:1740-4. 2009
    ..No intervention effect of soya foods on markers of inflammation was observed in this small study, but adiposity and early-life soya intake were related to higher leptin and MCP-1 levels...
  33. pmc Soy intake is related to a lower body mass index in adult women
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Eur J Nutr 47:138-44. 2008
    ..Experimental and epidemiologic studies suggest that soy may promote weight loss...
  34. pmc Urinary isoflavonoid excretion is similar after consuming soya milk and miso soup in Japanese-American women
    Gertraud Maskarinec
    Cancer Research Center of Hawai i, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Br J Nutr 100:424-9. 2008
    ..Therefore, recommendations favouring fermented soya foods are not justified as long as the intestinal microflora is capable of hydrolysing the isoflavone glucosides from non-fermented soya foods...
  35. pmc The volume of nipple aspirate fluid is not affected by 6 months of treatment with soy foods in premenopausal women
    Gertraud Maskarinec
    University of Hawaii Cancer Center, Honolulu, HI 96813, USA
    J Nutr 141:626-30. 2011
    ..50 for diet; P-interaction = 0.21 for diet with time). Contrary to an earlier report, soy foods in amounts consumed by Asians did not increase breast tissue activity as assessed by NAF volume...
  36. ncbi request reprint The relation of soy intake and isoflavone levels in nipple aspirate fluid
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, Hawaii 96813, USA
    Eur J Cancer Prev 17:67-70. 2008
    ..These findings show that isoflavonoids are present in breast fluid and may act directly on breast tissue...
  37. doi request reprint Overweight and obesity at different times in life as risk factors for non-Hodgkin's lymphoma: the multiethnic cohort
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Cancer Epidemiol Biomarkers Prev 17:196-203. 2008
    ..These findings indicate that weight at age 21 may represent lifetime adiposity better than body weight at cohort entry. Alternatively, weight at age 21 may be more relevant for the etiology of NHL...
  38. ncbi request reprint Mammographic density and breast cancer risk: the multiethnic cohort study
    Gertraud Maskarinec
    Cancer Etiology Program, Cancer Research Center of Hawaii, Honolulu, HI 96813, USA
    Am J Epidemiol 162:743-52. 2005
    ..Because the risk estimates appeared higher for Caucasians and Native Hawaiians than for Japanese women, ethnicity-specific models may be necessary to predict risk from breast density in different ethnic groups...
  39. ncbi request reprint A randomized isoflavone intervention among premenopausal women
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, Hawaii 96813, USA
    Cancer Epidemiol Biomarkers Prev 11:195-201. 2002
    ..However, isoflavones alone may have different effects on the reproductive cycle than isoflavones present in soy foods...
  40. pmc The use of breast conserving surgery: linking insurance claims with tumor registry data
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, University of Hawaii at Manoa, 1236 Lauhala Street, Honolulu, Hawaii 96813, USA
    BMC Cancer 2:3. 2002
    ..The purpose of this study was to use insurance claims and tumor registry data to examine determinants of breast conserving surgery (BCS) in women with early stage breast cancer...
  41. ncbi request reprint Comparison of mammographic densities and their determinants in women from Japan and Hawaii
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, HI 96813, USA
    Int J Cancer 102:29-33. 2002
    ..Therefore, when comparing ethnic groups with distinct physical proportions, the absolute size of the dense areas appears to be a better measure of breast cancer risk than the relative density...
  42. ncbi request reprint The effect of migration on cancer incidence among Japanese in Hawaii
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, Hawaii 96813, USA
    Ethn Dis 14:431-9. 2004
    ..This analysis compared cancer incidence trends among Japanese in Japan, and Japanese and Caucasians in Hawaii, between 1960 and 1997, and estimated the impact of migration on the incidence of different cancers...
  43. ncbi request reprint A 2-year soy intervention in premenopausal women does not change mammographic densities
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, HI, USA
    J Nutr 134:3089-94. 2004
    ..After 2 y of intervention, we observed no significant differences in mammographic densities by intervention status, but it appears that soy consumption throughout life may have some effect on breast density...
  44. ncbi request reprint The relation between nutritional factors and insulin-like growth factor-I in premenopausal women of different ethnicity
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Eur J Nutr 44:105-13. 2005
    ..Alterations in the insulin-like growth factor-I (IGF-I) system have been proposed as a metabolic link between nutritional factors and cancer risk...
  45. ncbi request reprint Mammographic densities in a one-year isoflavone intervention
    G Maskarinec
    Cancer Research Center of Hawaii, Honolulu, HI 96813, USA
    Eur J Cancer Prev 12:165-9. 2003
    ..Although this exploratory study had limited power, it appears that isoflavones do not exert an estrogenic effect similar to hormone replacement therapy on mammographic density...
  46. ncbi request reprint Three measures show high compliance in a soy intervention among premenopausal women
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, HI 96813, USA
    J Am Diet Assoc 103:861-6. 2003
    ..To evaluate adherence to a soy-based diet among premenopausal women...
  47. ncbi request reprint Influences of ethnicity, treatment, and comorbidity on breast cancer survival in Hawaii
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    J Clin Epidemiol 56:678-85. 2003
    ....
  48. pmc Urinary isoflavone excretion as a compliance measure in a soy intervention among young girls: a pilot study
    G Maskarinec
    Cancer Research Center of Hawaii, Honolulu, HI 96813, USA
    Eur J Clin Nutr 59:369-75. 2005
    ..To investigate the compliance of young girls with a soy intervention...
  49. ncbi request reprint Effects of a 2-year randomized soy intervention on sex hormone levels in premenopausal women
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Cancer Epidemiol Biomarkers Prev 13:1736-44. 2004
    ..The goal of this trial among premenopausal women was to examine the effect of soy foods on menstrual cycle length and circulating sex hormone levels...
  50. ncbi request reprint Dietary changes among cancer survivors
    G Maskarinec
    Cancer Research of Hawaii, Honolulu 96813, USA
    Eur J Cancer Care (Engl) 10:12-20. 2001
    ..Increasing communication with health care providers may prevent the use of extreme diets, unproven and possibly harmful supplements and reduce exaggerated hopes related to the benefits of a particular dietary regimen...
  51. pmc Urinary sex steroid excretion levels during a soy intervention among young girls: a pilot study
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu 96813, USA
    Nutr Cancer 52:22-8. 2005
    ..047, respectively). Similar differences were observed after stratification by breast development and menarcheal status. The association of sex steroid levels with pubertal development supports the validity of the sex steroid measurements...
  52. ncbi request reprint Exploring the feasibility and effects of a high-fruit and -vegetable diet in healthy women
    G Maskarinec
    Cancer Research Center of Hawaii, Honolulu 96813, USA
    Cancer Epidemiol Biomarkers Prev 8:919-24. 1999
    ..These results suggest that motivated women can substantially increase their fruit and vegetable intake, which leads to a notable increase in plasma carotenoid levels...
  53. ncbi request reprint Breast cancer--interaction between ethnicity and environment
    G Maskarinec
    Cancer Research Center of Hawaii, Honolulu 96813, USA
    In Vivo 14:115-23. 2000
    ....
  54. ncbi request reprint A case-control study of mammographic densities in Hawaii
    G Maskarinec
    Cancer Research Center of Hawaii, Honolulu 96813, USA
    Breast Cancer Res Treat 63:153-61. 2000
    ....
  55. ncbi request reprint Dietary patterns are associated with body mass index in multiethnic women
    G Maskarinec
    Cancer Research Center of Hawaii, Honolulu, HI, USA
    J Nutr 130:3068-72. 2000
    ..The study results support the ideas that choosing the right foods may be important in weight control and that food-based dietary patterns may be useful in dietary counseling...
  56. ncbi request reprint Ethnic differences in complementary and alternative medicine use among cancer patients
    G Maskarinec
    Cancer Research Center of Hawaii, University of Hawaii at Manoa, Honolulu 96813, USA
    J Altern Complement Med 6:531-8. 2000
    ..Given the ethnically diverse population in Hawaii, we hypothesized that CAM use may be related to the ancestry and the cultural heritage of cancer patients...
  57. pmc An investigation of soy intake and mammographic characteristics in Hawaii
    G Maskarinec
    Cancer Research Center of Hawaii, Honolulu, Hawaii 96813, USA
    Breast Cancer Res 3:134-41. 2001
    ....
  58. ncbi request reprint Ethnic differences in trends and determinants of cigarette smoking in Hawaii
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, Hawaii 96813, USA
    Ethn Dis 15:316-23. 2005
    ..The goal of this project was to investigate the trends and predictors of cigarette smoking among a population of Caucasians, Japanese, Chinese, Filipino, and Native Hawaiians...
  59. ncbi request reprint Ethnic differences in mammographic densities
    G Maskarinec
    Cancer Research Center of Hawaii, Honolulu, Hawaii 96813, USA
    Int J Epidemiol 30:959-65. 2001
    ..The purpose of this project was to explore the hypothesis that women from ethnic groups at high breast cancer risk are more likely to have high levels of densities than women from low breast cancer risk groups...
  60. ncbi request reprint A cross-sectional investigation of breast density and insulin-like growth factor I
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Int J Cancer 107:991-6. 2003
    ....
  61. pmc Obesity and breast cancer survival in ethnically diverse postmenopausal women: the Multiethnic Cohort Study
    Shannon M Conroy
    Epidemiology Program, University of Hawaii Cancer Center, 1236 Lauhala Street, Honolulu, HI, 96813, USA
    Breast Cancer Res Treat 129:565-74. 2011
    ..63) mortality. Our findings are consistent with the literature that maintaining moderate weight throughout adult life may be beneficial for breast cancer survival in women and this appears to hold for all ethnic groups...
  62. ncbi request reprint Serum insulin-like growth factor-I levels among women in Hawaii and Japan with different levels of tofu intake
    Yumie Takata
    Cancer Research Center of Hawaii, Honolulu, HI, USA
    Nutr Cancer 56:136-42. 2006
    ..These findings suggest that a diet rich in soy foods and low in meats may be related to lower IGF-I levels, but it is unclear whether soy or other characteristics of diet and lifestyle are responsible for this association...
  63. pmc Dietary patterns and the risk of non-Hodgkin lymphoma: the Multiethnic Cohort
    Eva Erber
    Cancer Research Center of Hawai i, University of Hawaii, Honolulu, HI, USA
    Leuk Lymphoma 50:1269-75. 2009
    ..03). The lack of significant results in men and women indicates a limited role of diet in NHL etiology, but dietary patterns might have ethnic- and subgroup-specific effects on NHL...
  64. pmc Erythrocyte membrane fatty acid composition, serum lipids, and non-Hodgkin's lymphoma risk in a nested case-control study: the multiethnic cohort
    Yukiko Morimoto
    University of Hawaii Cancer Center, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Cancer Causes Control 23:1693-703. 2012
    ..Composition of dietary fatty acid intake, which influences cytokine production, may contribute to the development of non-Hodgkin's lymphoma (NHL). Serum lipid levels may serve as biomarkers of inflammation associated with NHL risk...
  65. pmc Complementary and alternative medicine use and breast cancer prognosis: a pooled analysis of four population-based studies of breast cancer survivors
    Rayna Kim Matsuno
    University of Hawaii Cancer Center, Department of Epidemiology, Honolulu, Hawaii 96813, USA
    J Womens Health (Larchmt) 21:1252-8. 2012
    ..Complementary and alternative medicine (CAM) use is common among breast cancer survivors, but little is known about its impact on survival...
  66. pmc Comparison of modifiable health behaviours between persons with and without cancer: the Multiethnic Cohort
    Nicholas J Ollberding
    Epidemiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA
    Public Health Nutr 14:1796-804. 2011
    ..To compare the prevalence of modifiable risk factors for cancer and other chronic diseases between adult cancer survivors and persons with no history of cancer...
  67. pmc Plasma matrix metalloproteinases and postmenopausal breast cancer risk: a nested case-control study in the Multiethnic Cohort study
    Yeonju Kim
    Epidemiology Program, University of Hawai i Cancer Center, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Breast Cancer Res Treat 136:837-45. 2012
    ..05). Few significant differences in risk by levels of the MMPs were found by any of the clinical variables. Circulating MMPs were not associated with postmenopausal breast cancer risk...
  68. pmc IGF1, IGFBP1, and IGFBP3 genes and mammographic density: the Multiethnic Cohort
    Martijn Verheus
    Epidemiology Program, Cancer Research Center of Hawaii, Honolulu, HI
    Int J Cancer 127:1115-23. 2010
    ..Given the large number of SNPs tested and the few borderline significant results, we only found weak evidence that genetic variations in IGFBP1 or IGFBP3 may be related to mammographic density. Ethnicity may modify these relations...
  69. pmc The relation of urinary estrogen metabolites with mammographic densities in premenopausal women
    Gertraud Maskarinec
    University of Hawaii Cancer Center, Honolulu, HI 96813, USA
    Cancer Epidemiol 36:e310-6. 2012
    ..g., the ratio of 2-hydroxyestrone (2-OHE(1)) and 16α-OHE(1) may influence breast cancer risk. This study examined the association of urinary estrogen metabolites with breast density in premenopausal women...
  70. pmc Associations between obesity and serum lipid-soluble micronutrients among premenopausal women
    Weiwen Chai
    Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA
    Nutr Res 30:227-32. 2010
    ..Our results indicate potential influences of obesity on serum levels of lipid-soluble micronutrients and suggest that metabolism of provitamin A carotenoids may contribute to the differences observed...
  71. ncbi request reprint A comparison of dietary habits among women in Japan and Hawaii
    Yumie Takata
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Public Health Nutr 7:319-26. 2004
    ..To compare the dietary habits of Japanese women in Japan with those of Japanese and Caucasian women living in Hawaii...
  72. pmc Estrogen levels in nipple aspirate fluid and serum during a randomized soy trial
    Gertraud Maskarinec
    University of Hawaii Cancer Center, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Cancer Epidemiol Biomarkers Prev 20:1815-21. 2011
    ..On the basis of hypothesized protective effect, we examined the effect of soy foods on estrogens in nipple aspirate fluid (NAF) and serum, possible indicators of breast cancer risk...
  73. pmc Association between breast cancer susceptibility loci and mammographic density: the Multiethnic Cohort
    Christy G Woolcott
    Cancer Research Center of Hawaii, University of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Breast Cancer Res 11:R10. 2009
    ..Mammographic density is a strong risk factor for breast cancer. Our objective was to examine its association with polymorphisms identifying breast cancer susceptibility loci that were ascertained in recent genome-wide association studies...
  74. ncbi request reprint Ethnic differences in choices of health information by cancer patients using complementary and alternative medicine: an exploratory study with correspondence analysis
    Hisako Kakai
    Cancer Research Center of Hawaii, University of Hawaii at Manoa, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Soc Sci Med 56:851-62. 2003
    ..For medical practice, these findings indicate the need for healthcare providers to assist cancer patients to obtain accurate health information in a culturally sensitive way...
  75. ncbi request reprint Mammographic densities and circulating hormones: a cross-sectional study in premenopausal women
    Jihae J Noh
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Breast 15:20-8. 2006
    ....
  76. ncbi request reprint An investigation of mammographic density and gene variants in healthy women
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, Honolulu, HI 96813, USA
    Int J Cancer 112:683-8. 2004
    ..Our data suggest lower mammographic density for women carrying the COMT and CYP1A2 variant alleles than for women carrying the common alleles, though this is the opposite of what is commonly hypothesized from the enzyme function...
  77. ncbi request reprint Pilot study of dietary influences on mammographic density in pre- and postmenopausal Hispanic and non-Hispanic white women
    Cynthia A Thomson
    Department of Nutritional Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson 85721 0038, USA
    Menopause 14:243-50. 2007
    ....
  78. doi request reprint Association of leptin, 25-hydroxyvitamin D, and parathyroid hormone in women
    Micah Maetani
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Nutr Cancer 61:225-31. 2009
    ....
  79. pmc Tobacco use among Native Hawaiian middle school students: its prevalence, correlates and implications
    Karen Glanz
    Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA
    Ethn Health 12:227-44. 2007
    ..This study also explored whether social influence, psychosocial and cultural factors are associated with cigarette use in this sample...
  80. pmc Dietary patterns and risk for diabetes: the multiethnic cohort
    Eva Erber
    Cancer Research Center, University of Hawaii, Honolulu, Hawaii, USA
    Diabetes Care 33:532-8. 2010
    ..005) than in men (0.92 [0.83-1.02], P(trend) = 0.04). CONCLUSIONS Foods high in meat and fat appear to confer a higher diabetes risk in all ethnic groups, whereas the effects of other dietary patterns vary by sex and ethnicity...
  81. ncbi request reprint Associations between mammographic density and body composition in Hispanic and non-Hispanic white women by menopause status
    Graciela Caire-Juvera
    Nutrition Department, Centro de Investigacion en Alimentacion y Desarrollo, Sonora, Mexico
    Menopause 15:319-25. 2008
    ..To evaluate the associations of body composition, including percentage of lean and fat mass, with the percentage of mammographic density and mammographic dense area among pre- and postmenopausal Hispanic and non-Hispanic white women...
  82. ncbi request reprint Validation of a soy questionnaire with repeated dietary recalls and urinary isoflavone assessments over one year
    Andrew E Williams
    Cancer Research Center of Hawaii, Honolulu, HI 96813, USA
    Nutr Cancer 47:118-25. 2003
    ....
  83. ncbi request reprint Activating multi-ethnic youth for smoking prevention: design, baseline findings, and implementation of project SPLASH
    Karen Glanz
    Rollins School of Public Health, Emory UniversityNE, Atlanta, GA 30322
    J Cancer Educ 22:56-61. 2007
    ..This article describes an innovative tobacco prevention trial, and reports baseline characteristics of participants and findings about implementation of the curriculum...
  84. ncbi request reprint Cancer research center hotline: mammographic density as a marker for breast cancer risk
    Gertraud Maskarinec
    Cancer Research Center of Hawai i, USA
    Hawaii Med J 65:117-8. 2006
  85. doi request reprint Puberty, body fat, and breast density in girls of several ethnic groups
    Rachel Novotny
    Department of Human Nutrition, Food and Animal Sciences, College of Tropical Agriculture and Human Resources, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA
    Am J Hum Biol 23:359-65. 2011
    ..We examined breast density by dual energy X-ray absorptiometry (DXA) in relation to pubertal maturation and body fatness among girls of several ethnic groups, which may suggest important risk factors for future breast cancer...
  86. pmc Leptin, adiponectin, and obesity among Caucasian and Asian women
    Shannon M Conroy
    University of Hawaii Cancer Center, Cancer Epidemiology Program, Honolulu, HI 96813, USA
    Mediators Inflamm 2011:253580. 2011
    ..64) and with adiponectin (β=-0.95 versus β=-0.75) than Caucasians. Compared to Caucasians of similar BMI, Asians may experience a higher chronic disease risk due to lower levels of adiponectin despite their lower levels of leptin...
  87. pmc Common immune-related risk factors and incident non-Hodgkin lymphoma: the multiethnic cohort
    Eva Erber
    Epidemiology Program, Cancer Research Center of Hawai i, Honolulu, HI 96813, USA
    Int J Cancer 125:1440-5. 2009
    ....
  88. pmc Soy intervention in adolescent girls: design and implementation
    Caryn Oshiro
    Human Nutrition, Food and Animal Sciences, University of Hawaii at Manoa, Honolulu, USA
    J Nutr Educ Behav 36:204-8. 2004
    ..Future studies should also consider the maturity and sense of responsibility of participants to achieve compliance...
  89. pmc A comparison of breast density measures between mothers and adolescent daughters
    Gertraud Maskarinec
    Epidemiology Program, University of Hawaii Cancer Center, Honolulu, USA
    BMC Cancer 11:330. 2011
    ..Based on the importance of breast density as a predictor of breast cancer risk, we examined the heritable component of breast measures in mothers and daughters using Dual Energy X-ray Absorptiometry (DXA)...
  90. pmc Dietary vitamin D and risk of non-Hodgkin lymphoma: the multiethnic cohort
    Eva Erber
    Cancer Research Center of Hawai i, University of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Br J Nutr 103:581-4. 2010
    ..High dietary intake of vitamin D did not show a protective effect against NHL within the MEC except among African Americans, possibly because vitamin D production due to sun exposure is limited in this population...
  91. ncbi request reprint NAT2, meat consumption and colorectal cancer incidence: an ecological study among 27 countries
    Simona Ognjanovic
    Epidemiology Program, Cancer Research Center of Hawaii, 1236 Lauhala Street, Suite 407, Honolulu, HI 96813, USA
    Cancer Causes Control 17:1175-82. 2006
    ..These data suggest that, in combination with meat intake, some proportion of the international variability in CRC incidence may be attributable to genetic susceptibility to heterocyclic amines, as determined by NAT2 genotype...
  92. pmc Analysis of urinary estrogens, their oxidized metabolites, and other endogenous steroids by benchtop orbitrap LCMS versus traditional quadrupole GCMS
    Adrian A Franke
    University of Hawaii Cancer Center, Clinical Sciences Program, Honolulu, HI 96813, USA
    Anal Bioanal Chem 401:1319-30. 2011
    ..In contrast, orbitrap-based LCMS can detect more estrogens, is faster, less costly, allows post-data acquisition reinterrogation of certain analytes that had not been targeted a priori, and requires much less urine...
  93. pmc Breast cancer risk and hysterectomy status: the Multiethnic Cohort study
    Christy G Woolcott
    Cancer Research Center of Hawaii, University of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Cancer Causes Control 20:539-47. 2009
    ..Because hysterectomy prevalence varies by ethnicity, the secondary objective was to examine whether inclusion of women with hysterectomies affects the estimates of breast cancer risk by ethnicity...
  94. ncbi request reprint Nonsteroidal antiinflammatory drugs and breast cancer risk: the multiethnic cohort
    Jasmeet K Gill
    Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI, USA
    Am J Epidemiol 166:1150-8. 2007
    ..This study found duration of current other NSAID use to be protective against breast cancer risk...
  95. ncbi request reprint Breast cancer treatment among women of different ethnicity in Hawaii
    Brian F Issell
    Cancer Research Center of Hawaii, Honolulu, Hawaii 96813, USA
    Cancer Invest 23:497-504. 2005
    ..We conducted this study to test for ethnic differences in treatment compliance with established guidelines while adjusting for stage at diagnosis and other disease characteristics...
  96. pmc Dietary fiber, magnesium, and glycemic load alter risk of type 2 diabetes in a multiethnic cohort in Hawaii
    Beth N Hopping
    Department of Epidemiology, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI 96813, USA
    J Nutr 140:68-74. 2010
    ..These findings suggest that protection against diabetes can be achieved through food choices after taking into account body weight, but, due to differences in commonly consumed foods, risk estimates may differ by ethnic group...
  97. ncbi request reprint Association of genetic polymorphisms with serum estrogens measured multiple times during a 2-year period in premenopausal women
    Galina Lurie
    Cancer Research Center of Hawaii, University of Hawaii, 1236 Lauhala Street, Honolulu, Hawaii 96813, USA
    Cancer Epidemiol Biomarkers Prev 14:1521-7. 2005
    ..37 versus 1.76; P = 0.002). These data suggest that CYP1A2*1F is associated with lower circulating levels of E2, and that it may be a susceptibility locus for breast cancer...
  98. ncbi request reprint Determinants of the degree of complementary and alternative medicine use among patients with cancer
    Dianne M Shumay
    The Cancer Research Center of Hawaii, Honolulu, HI 96813, USA
    J Altern Complement Med 8:661-71. 2002
    ....
  99. ncbi request reprint Mammographic density and dietary patterns: the multiethnic cohort
    Yumie Takata
    Cancer Research Center of Hawaii, Honolulu, Hawaii 96813, USA
    Eur J Cancer Prev 16:409-14. 2007
    ..The influence of diet on mammographic densities, however, appears to be fairly small. Analyses of both dietary patterns and single dietary factors seem equally informative in examining dietary associations with percentage density...
  100. ncbi request reprint Urinary isoflavonoids as a dietary compliance measure among premenopausal women
    Adrian A Franke
    Cancer Research Center of Hawaii, Honolulu, Hawaii 96813, USA
    Asia Pac J Clin Nutr 15:88-94. 2006
    ....
  101. ncbi request reprint Correspondence re: Jakes et al., Mammographic parenchymal patterns and self-reported soy intake in Singapore Chinese women. Cancer Epidemiol. Biomark. Prev., 11: 608-613, 2002
    Gertraud Maskarinec
    Cancer Epidemiol Biomarkers Prev 12:387; author reply 387. 2003

Research Grants21

  1. Effects of Soy on Estrogens in Breast Fluid and Urine
    Gertraud Maskarinec; Fiscal Year: 2007
    ..The NAF approach is the only way to learn more about the beneficial and adverse effects of soy directly in the female breast without applying invasive procedures to women without breast disease or surgery. ..
  2. Nutritional Risk Factors for Type 2 Diabetes in the Multiethnic Cohort
    Gertraud Maskarinec; Fiscal Year: 2007
    ..A better understanding of dietary and behavioral factors related to excess body weight and diabetes in Japanese and Native Hawaiians will help in developing preventive strategies to modify lifestyle factors. ..
  3. Inflammatory Markers in a 2-Year Soy Intervention among Premenopausal Women
    Gertraud Maskarinec; Fiscal Year: 2007
    ..The statistical analysis will apply general linear models to compare the levels of inflammatory markers by soy intake, while taking into account the repeated measurement design. ..
  4. Effects of Soy on Estrogens in Breast Fluid and Urine
    Gertraud Maskarinec; Fiscal Year: 2009
    ..The NAF approach is the only way to learn more about the beneficial and adverse effects of soy directly in the female breast without applying invasive procedures to women without breast disease or surgery. ..
  5. Cancer Control Research Training in Multiethnic Hawaii
    Gertraud Maskarinec; Fiscal Year: 2007
    ..This training environment, together with the proposed Program plan, provides an ideal opportunity for quality career development for cancer control scientists in the twenty-first century. ..
  6. Soy Consumption and Breast Tissue Proliferation
    Gertraud Maskarinec; Fiscal Year: 2006
    ....
  7. NESTED CASE CONTROL STUDY OF MAMMOGRAPHIC DENSITY
    Gertraud Maskarinec; Fiscal Year: 2002
    ....
  8. Breast Density, IGF-I, & Prolactin, in Four Populations
    Gertraud Maskarinec; Fiscal Year: 2004
    ..The statistical analysis will include mixed models to explore the relation between hormone levels and breast density while controlling for confounders and for clustering by study location. ..
  9. Effects of Soy on Estrogens in Breast Fluid and Urine
    Gertraud Maskarinec; Fiscal Year: 2010
    ..The NAF approach is the only way to learn more about the beneficial and adverse effects of soy directly in the female breast without applying invasive procedures to women without breast disease or surgery. ..