Research Topics
Species | Steve R MartinezSummaryAffiliation: University of California Country: USA Publications
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Publications
Rural-urban disparities in use of post-lumpectomy radiationSteve R Martinez
Department of Surgery, Division of Surgical Oncology, University of California at Davis, Sacramento, CA, USA
Med Oncol 29:3250-7. 2012..52; P < 0.001) areas had a decreased likelihood of undergoing RT relative to patients from urban areas. Patients from near-metro and rural areas are less likely to receive RT following lumpectomy for BCa than their urban counterparts...
Geographic variation in utilization of sentinel lymph node biopsy for intermediate thickness cutaneous melanomaSteve R Martinez
Division of Surgical Oncology, Department of Surgery, University of California at Davis, Sacramento, California 95817, USA
J Surg Oncol 106:807-10. 2012..Despite this, SLNB has not been uniformly adopted. We hypothesized that there are geographic areas of the United States where patients are less likely to receive SLNB...
Urban and non-urban disparities in the use of post-mastectomy radiation for breast cancerSteve R Martinez
Department of Surgery, Division of Surgical Oncology, University of California at Davis, Sacramento, CA, USA
Med Oncol 29:1523-8. 2012..Non-urban residents with LABC are less likely to receive indicated PMRT. This discrepancy may be due to limited RT access in non-urban areas. The lack of poorer OS and DSS due to this disparity requires further study...
Metastatic breast cancer mimicking benign fatty liver infiltrationSteve R Martinez
Department of Surgery, Division of Surgical Oncology, UC Davis Medical Center, Sacramento, California 95817, USA
Breast J 14:108. 2008
Do radiation use disparities influence survival in patients with advanced breast cancer?Steve R Martinez
Division of Surgical Oncology, Department of Surgery, University of California Davis, Sacramento, California 95817, USA
Cancer 118:196-204. 2012..They hypothesized that disparities in the use of RT were associated with survival differences favoring white patients...
A rational surgical approach to the treatment of distant melanoma metastasesSteve R Martinez
Division of Surgical Oncology, Department of Surgery, UC Davis Cancer Center, 4501 X Street, Suite 3010, Sacramento, CA 95817, USA
Cancer Treat Rev 34:614-20. 2008..Because it is effective, results in little morbidity and may be repeated, surgery should have a central role in the treatment of selected patients with American Joint Committee on Cancer (AJCC) stage IV melanoma...
Outcomes for lymph node-positive cutaneous melanoma over two decadesSteve R Martinez
Department of Surgery, Division of Surgical Oncology Sacramento, University of California at Davis, 4501 X Street, Suite 3010, Sacramento, CA 95817, USA
World J Surg 35:1567-72. 2011..Our aim was to demonstrate that, despite advances in treatment and surveillance of node-positive cutaneous melanoma, rates of overall survival (OS) and melanoma-specific survival (MSS) have not changed over the last two decades...
Disparities in the use of radiation therapy in patients with local-regionally advanced breast cancerSteve R Martinez
Department of Surgery, Division of Surgical Oncology, University of California Davis, Sacramento, CA, USA
Int J Radiat Oncol Biol Phys 78:787-92. 2010..Radiation therapy (RT) is indicated for the treatment of local-regionally advanced breast cancer (BCa)...
Medullary carcinoma of the breast: a population-based perspectiveSteve R Martinez
Department of Surgery, University of California Davis, Davis, CA, USA
Med Oncol 28:738-44. 2011..The improved OS seen with increasing LNY in node-negative patients suggests MCB may be currently understaged...
Racial and ethnic differences in treatment and survival among adults with primary extremity soft-tissue sarcomaSteve R Martinez
Division of Surgical Oncology, University of California at Davis Cancer Center, Sacramento, CA 95817, USA
Cancer 112:1162-8. 2008..The authors assessed racial/ethnic differences in patient- and tumor-specific characteristics, treatment, and disease-specific survival in a population of adults with ESTS...
Adjuvant external beam radiation for medullary thyroid carcinomaSteve R Martinez
Division of Surgical Oncology, Department of Surgery, UC Davis Cancer Center, University of California at Davis, Sacramento, California 95817, USA
J Surg Oncol 102:175-8. 2010..Adjuvant radiation is rarely used to treat medullary thyroid carcinoma (MTC). We hypothesized that external beam radiation therapy (EBRT) would improve overall survival (OS) in MTC patients...
Rare tumors through the looking glass: an examination of malignant cutaneous adnexal tumorsSteve R Martinez
Division of Surgical Oncology, Department of Surgery, UC Davis Cancer Center, 4501 X St, Ste 3010, Sacramento, CA 95817, USA
Arch Dermatol 147:1058-62. 2011..To identify prognostic factors related to malignant cutaneous adnexal tumors...
The role of surgery in treatment of stage IV melanomaShawn E Young
Division of Surgical Oncology and the Roy E. Coats Research Laboratories, John Wayne Cancer Institute at Saint John's Health Center, Santa Monica, California, USA
J Surg Oncol 94:344-51. 2006..Further, surgical resection can produce an immediate decrease in tumor burden with minimal morbidity and mortality at a reasonable cost...
Prognostic value of lymph node yield and metastatic lymph node ratio in medullary thyroid carcinomaMaya D Leggett
Department of Surgery, Division of Surgical Oncology, UC Davis Cancer Center, University of California at Davis, 4501 X Street, Suite 3010, Sacramento, CA, 95817, USA
Ann Surg Oncol 15:2493-9. 2008..We hypothesized that MTC survival is influenced by LNY and MLNR...
An evaluation of lymph node yield and lymph node ratio in well-differentiated thyroid carcinomaShannon H Beal
University of California at Davis, Department of Surgery, Division of Surgical Oncology, UC Davis Cancer Center, Sacramento, California 95817, USA
Am Surg 76:28-32. 2010..The decrease in survival associated with increasing LNY, even in node-negative patients, indicates that nodal understaging is inconsequential to WDTC survival...
Survival in 12,653 breast cancer patients with extensive axillary lymph node metastasis in the anthracycline eraShannon H Beal
Department of Surgery, Division of Surgical Oncology, University of California Davis, Sacramento, CA 95817, USA
Med Oncol 27:1420-4. 2010..90, 95% Confidence Interval [CI] 0.84-0.96) and DSS (HR 0.84, CI 0.79-0.91). Both OS and DSS are poor in patients with extensive ALN metastases. Patients with advanced breast cancer treated in the post-AE demonstrated superior OS and DSS...
Predicting survival for well-differentiated liposarcoma: the importance of tumor locationCaitlin A Smith
Division of Surgical Oncology, UC Davis Cancer Center, Sacramento, California 95817, USA
J Surg Res 175:12-7. 2012..Although well-differentiated liposarcoma (WD Lipo) is a low grade neoplasm with a negligible risk of metastatic disease, it can be locally aggressive. We hypothesized that survival for WD Lipo varies significantly based on tumor location...
Histologic type predicts survival in patients with retroperitoneal soft tissue sarcomaWarren Tseng
Department of Surgery, Division of Surgical Oncology, University of California, Davis Medical Center, Sacramento, Califronia, USA
J Surg Res 172:123-30. 2012..We sought to examine the importance of histologic type as a prognostic factor among patients with RPSTS...
Utilization of lymph node assessment in patients with ductal carcinoma in situ treated with lumpectomyDhruvil R Shah
Department of Surgery, Division of Surgical Oncology, University of California Davis, Sacramento, California, USA
J Surg Res 177:e21-6. 2012..Lymph node assessment (LNA), including sentinel lymph node biopsy (SLNB), is controversial in patients undergoing lumpectomy for ductal carcinoma in situ (DCIS). Our goal was to identify factors influencing LNA in these patients...
Sacramento area breast cancer epidemiology study: use of postmastectomy breast reconstruction along the rural-to-urban continuumWarren H Tseng
Department of Surgery, Division of Surgical Oncology, University of California, Davis, Sacramento, CA 95817, USA
Plast Reconstr Surg 126:1815-24. 2010..The authors hypothesized that breast cancer patients in urban counties would have higher rates of postmastectomy breast reconstruction relative to patients in surrounding near-metro and rural counties...
Contiguous organ resection is safe in patients with retroperitoneal sarcoma: An ACS-NSQIP analysisWarren H Tseng
Division of Surgical Oncology, Department of Surgery, University of California, Davis Medical Center, Sacramento, California, USA
J Surg Oncol 103:390-4. 2011..We examined rates of 30-day morbidity and mortality following resection of RPS utilizing data from the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database...
Nomogram to predict risk of 30-day morbidity and mortality for patients with disseminated malignancy undergoing surgical interventionWarren H Tseng
Division of Surgical Oncology, Department of Surgery, University of California at Davis Medical Center, Sacramento, CA 95817, USA
Ann Surg 254:333-8. 2011..To estimate individual risk of 30-day surgical morbidity and mortality after surgical intervention for patients with disseminated malignancy (DMa)...
Treatment disparities in Hispanic rectal cancer patients: a SEER database studySteve R Martinez
Division of Surgical Oncology, John Wayne Cancer Institute, Santa Monica, California 90404, USA
Am Surg 72:906-8. 2006..Further studies are required to assess the impact of these treatment disparities on patient outcome...
Interaction of histologic subtype and histologic grade in predicting survival for soft-tissue sarcomasRobert J Canter
Division of Surgical Oncology, University of California Davis Cancer Center, Sacramento, CA, USA
J Am Coll Surg 210:191-198.e2. 2010..Histologic grade is considered the paramount prognostic factor in predicting survival for soft-tissue sarcomas (STS). Increasing data suggest that histologic type substantially impacts STS behavior...
Lack of survival benefit following adjuvant radiation in patients with retroperitoneal sarcoma: a SEER analysisWarren H Tseng
Department of Surgery, Division of Surgical Oncology, University of California, Davis Medical Center, Sacramento, California 95817, USA
J Surg Res 168:e173-80. 2011..The benefit of radiation therapy (RT) among patients with retroperitoneal sarcoma (RPS) is controversial. We performed a retrospective analysis of the effect of RT on survival among RPS patients using a nationwide cancer registry...
Complete pathologic response to neoadjuvant radiotherapy is predictive of oncological outcome in patients with soft tissue sarcomaDhruvil Shah
Division of Surgical Oncology, University of California Davis Medical Center, Sacramento, CA, USA
Anticancer Res 32:3911-5. 2012..We sought to determine if complete pathological necrosis (pathCR) predicts favorable oncological outcome in soft tissue sarcoma (STS) patients receiving pre-operative radiation monotherapy (RT)...
Influence of specialty and clinical experience on treatment sequencing in the multimodal management of soft tissue extremity sarcomaNabil Wasif
Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA
Ann Surg Oncol 19:504-10. 2012..Our goal was to identify factors responsible for this variation...
Regulation of RUNX3 tumor suppressor gene expression in cutaneous melanomaMinoru Kitago
Department of Molecular Oncology, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, California, USA
Clin Cancer Res 15:2988-94. 2009..Aberration in RUNX3 expression has not been described for cutaneous melanoma. Therefore, we assessed the expression of RUNX3 in cutaneous melanoma and its regulatory mechanisms relative to tumor progression...
Metaplastic breast cancer: to radiate or not to radiate?Warren H Tseng
Division of Surgical Oncology, Department of Surgery, University of California Davis, Sacramento, CA, USA
Ann Surg Oncol 18:94-103. 2011..The role of radiation therapy (RT) is unclear for metaplastic breast cancer (MBC). We hypothesized that RT would improve overall survival (OS) and disease-specific survival (DSS)...
Tumor location predicts survival in cutaneous head and neck melanomaWarren H Tseng
Department of Surgery, Division of Surgical Oncology, University of California Davis, Sacramento, California, USA
J Surg Res 167:192-8. 2011..Prior studies documented poorer outcomes in patients with cutaneous head and neck melanoma (CHNM) relative to those with melanoma at other sites. We evaluated survival differences attributable to tumor location in patients with CHNM...
Negligible effect of perioperative epidural analgesia among patients undergoing elective gastric and pancreatic resectionsDhruvil R Shah
Division of Surgical Oncology, UC Davis Cancer Center, 4501 X Street, Sacramento, CA 95817, USA
J Gastrointest Surg 17:660-7. 2013..We sought to examine the effect of perioperative epidural analgesia vs. intravenous narcotic analgesia on perioperative outcomes including pain control, morbidity, and mortality in patients undergoing gastric and pancreatic resections...
P16 expression predicts necrotic response among patients with osteosarcoma receiving neoadjuvant chemotherapyDariusz Borys
Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, CA 95817, USA
Hum Pathol 43:1948-54. 2012..5; 95% confidence interval, 2.64-708.9; P=.008). In summary, immunohistochemical expression of P16 significantly correlates with chemotherapy response in osteosarcoma. P16 expression may be a useful biomarker to guide treatment selection...
The survival impact of the choice of surgical procedure after ipsilateral breast cancer recurrenceSteven L Chen
Department of Surgery, Division of Surgical Oncology, University of California Davis Medical Center, 4501 X St, Suite 3010, Sacramento, CA 95817, USA
Am J Surg 196:495-9. 2008..Many women with breast cancer recurrence previously treated with breast-conservation therapy desire repeat lumpectomies. We hypothesized that women undergoing mastectomy for breast cancer recurrence would show superior survival...
Utilization of sentinel lymph node biopsy in patients with ductal carcinoma in situ undergoing mastectomyDhruvil R Shah
Division of Surgical Oncology, Department of Surgery, University of California Davis, Sacramento, CA, USA
Ann Surg Oncol 20:24-30. 2013..Our objective was to identify factors influencing the utilization of SLNB in this population...
Surgical resident involvement is safe for common elective general surgery proceduresWarren H Tseng
Department of Surgery, Division of Surgical Oncology, University of California, Davis Medical Center, Sacramento, CA 95817, USA
J Am Coll Surg 213:19-26; discussion 26-8. 2011..Examining 7 common general surgery procedures, we evaluated the effect of SRI on perioperative morbidity and mortality and operative time (OpT)...
Radiographic and histologic response to neoadjuvant radiotherapy in patients with soft tissue sarcomaRobert J Canter
Division of Surgical Oncology, University of California Davis Medical Center, Sacramento, CA, USA
Ann Surg Oncol 17:2578-84. 2010..Limited data exist regarding the radiographic and histologic response of soft tissue sarcoma (STS) to neoadjuvant radiotherapy (RT)...
Adjuvant radiation therapy is associated with improved survival for adenoid cystic carcinoma of the breastJodi M Coates
Department of Surgery, University of California Davis, Sacramento, California, USA
J Surg Oncol 102:342-7. 2010..The role of adjuvant radiation therapy (RT) for adenoid cystic carcinoma (ACC) of the breast remains unclear...
Sentinel lymph node biopsy in patients with thick primary cutaneous melanoma: patterns of use and underuse utilizing a population-based modelSteve R Martinez
Division of Surgical Oncology, Department of Surgery, University of California at Davis, Saeramento, CA 95817, USA UC Davis Comprehensive Cancer Center, 4501 X Street, Suite 3010, Sacramento, CA 95817, USA
ISRN Dermatol 2013:315609. 2013..21, CI 0.07-0.62; P = 0.005). Conclusions. In particular, elderly patients are less likely to receive SLNB. Further research is needed to assess whether use of SLNB in this population is detrimental or beneficial...
Complete regression of subcutaneous and cutaneous metastatic melanoma with high-dose intralesional interleukin 2 in combination with topical imiquimod and retinoid creamMiki Shirakawa Garcia
Department of Dermatology, University of California Davis, School of Medicine, Sacramento, CA 95816, USA
Melanoma Res 21:235-43. 2011..These results support intralesional high-dose IL-2 as a very effective therapy for controlling cutaneous metastatic melanoma. Additional studies are needed to determine whether this therapy is associated with a survival benefit...
Can surgical therapy alone achieve long-term cure of melanoma metastatic to regional nodes?Shawn E Young
Division of Surgical Oncology and the Roy E Coates Research Laboratories, John Wayne Cancer Institute at St John s Health Center, Santa Monica, California, USA
Cancer J 12:207-11. 2006..Few series in the literature are able to refute this assertion. We therefore examined rates of long-term (> 15-25 years) survival for patients with regional (nodal) melanoma...
Estrogen receptor-alpha methylation predicts melanoma progressionTakuji Mori
Department of Molecular Oncology, Division of Surgical Oncology, John Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA
Cancer Res 66:6692-8. 2006..004] and overall survival (RR, 2.31; 95% CI, 1.41-5.58; P = 0.003) in biochemotherapy patients. Hypermethylated ER-alpha is a significant factor in melanoma progression. Serum methylated ER-alpha is an unfavorable prognostic factor...
Treatment options for metaplastic breast cancerDhruvil R Shah
Division of Surgical Oncology, UC Davis Comprehensive Cancer, Sacramento, CA 95817, USA
ISRN Oncol 2012:706162. 2012..This paper serves as a summation of current literature on approaches to the multidisciplinary treatment of patients with MBC...
Initial characterization of a dedicated breast PET/CT scanner during human imagingSpencer L Bowen
Department of Biomedical Engineering, UC Davis, Davis, California, USA
J Nucl Med 50:1401-8. 2009..We have constructed a dedicated breast PET/CT scanner capable of high-resolution functional and anatomic imaging. Here, we present an initial characterization of scanner performance during patient imaging...
Cardiac injury during needle localized surgical breast biopsySteve R Martinez
Department of Surgery, Health Sciences Center, SUNY at Stony Brook, Stony Brook, New York 11794, USA
J Surg Oncol 82:261-5. 2003..The wire was pulled and the patient managed non-operatively with close monitoring that included plain chest radiographs, electrocardiography, and echocardiography. The literature regarding complications of the procedure was reviewed...
The utility of estrogen receptor, progesterone receptor, and Her-2/neu status to predict survival in patients undergoing hepatic resection for breast cancer metastasesSteve R Martinez
Department of Surgical Oncology, Division of Gastrointestinal Surgery, John Wayne Cancer Institute, 2200 Santa Monica Blvd, Santa Monica, CA 90404, USA
Am J Surg 191:281-3. 2006..Hepatic metastases from breast cancer signal a dismal prognosis, with a median survival of 9.5 months...
Detection of circulating tumor cells in early-stage breast cancer metastasis to axillary lymph nodesTaku Nakagawa
Department of Molecular Oncology, John Wayne Cancer Institute, Saint John s Health Center, Santa Monica, California 90404, USA
Clin Cancer Res 13:4105-10. 2007....
Novel effective drugs and evolving ablation technology: a more comprehensive approach to hepatic malignanciesAnton J Bilchik
Ann Surg Oncol 11:458-9. 2004
Molecular markers in malignant cutaneous melanoma: gift horse or one-trick pony?Steve R Martinez
Department of Molecular Oncology, John Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, California 90404, USA
J Cell Biochem 96:473-83. 2005....
Chemokine receptor CXCR4 expression in patients with melanoma and colorectal cancer liver metastases and the association with disease outcomeJoseph Kim
Department of Molecular Oncology, Gastrointestinal Cancer Section, John Wayne Cancer Institute, Saint John's Health Center, Santa Monica, CA 90404, USA
Ann Surg 244:113-20. 2006..Quantitative analysis of CXCR4 gene expression in patients with liver metastases has prognostic significance for disease outcome...
Proteomic profiling of primary breast cancer predicts axillary lymph node metastasisTaku Nakagawa
Department of Molecular Oncology, Division of Biostatistics, and Joyce Eisenberg Keefer Breast Center, John Wayne Cancer Institute, Santa Monica, CA 90404, USA
Cancer Res 66:11825-30. 2006..016 and 0.0083, respectively). ProteinChip array analysis identified differential protein peaks in primary breast cancers that predict the presence and number of ALN metastases and non-SLN status...
