Ernest Martinez

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Multi-protein complexes in eukaryotic gene transcription
    Ernest Martinez
    Department of Biochemistry, University of California, Riverside, CA 92521, USA
    Plant Mol Biol 50:925-47. 2002
  2. pmc Core promoter-selective coregulators of transcription by RNA polymerase II
    Ernest Martinez
    Department of Biochemistry, University of California at Riverside, Riverside, CA, USA
    Transcription 3:295-9. 2012
  3. pmc STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation
    Xiaohui Liu
    Department of Biochemistry, University of California, Riverside, Riverside, CA 92521, USA
    Mol Cell Biol 28:108-21. 2008
  4. pmc Max is acetylated by p300 at several nuclear localization residues
    Francesco Faiola
    Department of Biochemistry, University of California Riverside, Riverside, CA 92521, USA
    Biochem J 403:397-407. 2007
  5. pmc Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein
    Yuan Liang Wang
    Department of Biochemistry, University of California at Riverside, CA 92521, USA
    J Biol Chem 283:33808-15. 2008
  6. pmc Core promoter-selective function of HMGA1 and Mediator in Initiator-dependent transcription
    Muyu Xu
    Department of Biochemistry, University of California at Riverside, Riverside, California 92521, USA
    Genes Dev 25:2513-24. 2011
  7. doi request reprint Purification of multiprotein histone acetyltransferase complexes
    Yuan Liang Wang
    Department of Biochemistry, University of California, Riverside, CA, USA
    Methods Mol Biol 809:427-43. 2012
  8. pmc Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription
    Francesco Faiola
    Department of Biochemistry, University of California Riverside, Riverside, CA 92521, USA
    Mol Cell Biol 25:10220-34. 2005
  9. ncbi request reprint Six lysine residues on c-Myc are direct substrates for acetylation by p300
    Kangling Zhang
    Department of Chemistry, University of California at Riverside, Riverside, CA 92521, USA
    Biochem Biophys Res Commun 336:274-80. 2005
  10. ncbi request reprint Reconstitution of an E box-binding Myc:Max complex with recombinant full-length proteins expressed in Escherichia coli
    Anthony Farina
    Department of Biochemistry, University of California, Riverside, CA 92521, USA
    Protein Expr Purif 34:215-22. 2004

Research Grants

  1. Mechanisms of Transcription Regulation by c-Myc
    Ernest Martinez; Fiscal Year: 2007

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Multi-protein complexes in eukaryotic gene transcription
    Ernest Martinez
    Department of Biochemistry, University of California, Riverside, CA 92521, USA
    Plant Mol Biol 50:925-47. 2002
    ..Another emerging theme is the multi-functional nature of chromatin-modifying cofactor complexes that appear to couple gene-specific transcription to other cellular processes...
  2. pmc Core promoter-selective coregulators of transcription by RNA polymerase II
    Ernest Martinez
    Department of Biochemistry, University of California at Riverside, Riverside, CA, USA
    Transcription 3:295-9. 2012
    ....
  3. pmc STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation
    Xiaohui Liu
    Department of Biochemistry, University of California, Riverside, Riverside, CA 92521, USA
    Mol Cell Biol 28:108-21. 2008
    ..These results suggest a novel STAF65gamma-dependent function of STAGA-type complexes in cell proliferation and transcription activation by MYC postloading of TFIID and RNA polymerase II that involves direct recruitment of core Mediator...
  4. pmc Max is acetylated by p300 at several nuclear localization residues
    Francesco Faiola
    Department of Biochemistry, University of California Riverside, Riverside, CA 92521, USA
    Biochem J 403:397-407. 2007
    ..These results uncover novel post-translational modifications of Max and suggest the potential regulation of specific Max complexes by p300 and reversible acetylation...
  5. pmc Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein
    Yuan Liang Wang
    Department of Biochemistry, University of California at Riverside, CA 92521, USA
    J Biol Chem 283:33808-15. 2008
    ..These results suggest that vertebrate ATAC-type and STAGA-type complexes link specific extracellular signals to modification of chromatin structure and regulation of the basal transcription machinery...
  6. pmc Core promoter-selective function of HMGA1 and Mediator in Initiator-dependent transcription
    Muyu Xu
    Department of Biochemistry, University of California at Riverside, Riverside, California 92521, USA
    Genes Dev 25:2513-24. 2011
    ..Our results suggest a core promoter-specific regulation of Mediator and the basal transcription machinery by HMGA1...
  7. doi request reprint Purification of multiprotein histone acetyltransferase complexes
    Yuan Liang Wang
    Department of Biochemistry, University of California, Riverside, CA, USA
    Methods Mol Biol 809:427-43. 2012
    ..These methods have been used to purify and characterize different human GCN5 HAT complexes that retain activity toward their physiological substrates in vitro...
  8. pmc Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription
    Francesco Faiola
    Department of Biochemistry, University of California Riverside, Riverside, CA 92521, USA
    Mol Cell Biol 25:10220-34. 2005
    ..Our results suggest dual roles for p300/CBP in Myc regulation: as a Myc coactivator that stabilizes Myc and as an inducer of Myc instability via direct Myc acetylation...
  9. ncbi request reprint Six lysine residues on c-Myc are direct substrates for acetylation by p300
    Kangling Zhang
    Department of Chemistry, University of California at Riverside, Riverside, CA 92521, USA
    Biochem Biophys Res Commun 336:274-80. 2005
    ..Our results further indicate that p300 can acetylate DNA-bound Myc:Max complexes and that acetylated Myc:Max heterodimers efficiently interact with Miz-1...
  10. ncbi request reprint Reconstitution of an E box-binding Myc:Max complex with recombinant full-length proteins expressed in Escherichia coli
    Anthony Farina
    Department of Biochemistry, University of California, Riverside, CA 92521, USA
    Protein Expr Purif 34:215-22. 2004
    ....

Research Grants5

  1. Mechanisms of Transcription Regulation by c-Myc
    Ernest Martinez; Fiscal Year: 2007
    ..This proposal constitutes the first phase of our long-term goal to understand the role of coactivators and acetylation in regulation of transcription and cell proliferation by Myc. ..