M Q Martindale

Summary

Affiliation: University of Hawaii
Country: USA

Publications

  1. pmc Cell proliferation is necessary for the regeneration of oral structures in the anthozoan cnidarian Nematostella vectensis
    Yale J Passamaneck
    Kewalo Marine Laboratory, Pacific Biosciences Research Center, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    BMC Dev Biol 12:34. 2012
  2. pmc Genomic organization, evolution, and expression of photoprotein and opsin genes in Mnemiopsis leidyi: a new view of ctenophore photocytes
    Christine E Schnitzler
    National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
    BMC Biol 10:107. 2012
  3. doi request reprint Evolution of development: the details are in the entrails
    Mark Q Martindale
    Kewalo Marine Laboratory, University of Hawaii, Honolulu, HI 96813, USA
    Curr Biol 23:R25-8. 2013
  4. pmc Development of the larval anterior neurogenic domains of Terebratalia transversa (Brachiopoda) provides insights into the diversification of larval apical organs and the spiralian nervous system
    Scott Santagata
    Long Island University Post, 720 Northern Blvd, Brookville, NY 11709, USA
    Evodevo 3:3. 2012
  5. pmc Lim homeobox genes in the Ctenophore Mnemiopsis leidyi: the evolution of neural cell type specification
    David K Simmons
    Kewalo Marine Laboratory, Department of Zoology, University of Hawaii at Manoa, Honolulu, HI, USA, 96813
    Evodevo 3:2. 2012
  6. pmc A comparative gene expression database for invertebrates
    Mattias Ormestad
    Kewalo Marine Laboratory, PBRC, University of Hawaii at Manoa, 41, Ahui Street, Honolulu, 96734, HI, USA
    Evodevo 2:17. 2011
  7. pmc Ciliary photoreceptors in the cerebral eyes of a protostome larva
    Yale J Passamaneck
    Kewalo Marine Laboratory, Pacific Biosciences Research Center, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    Evodevo 2:6. 2011
  8. pmc Gene expression in bryozoan larvae suggest a fundamental importance of pre-patterned blastemic cells in the bryozoan life-cycle
    Judith Fuchs
    Kewalo Marine Laboratory, Pacific Biosciences Research Center, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    Evodevo 2:13. 2011
  9. pmc Nuclear receptors from the ctenophore Mnemiopsis leidyi lack a zinc-finger DNA-binding domain: lineage-specific loss or ancestral condition in the emergence of the nuclear receptor superfamily?
    Adam M Reitzel
    Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA, USA
    Evodevo 2:3. 2011
  10. pmc A comprehensive fate map by intracellular injection of identified blastomeres in the marine polychaete Capitella teleta
    Néva P Meyer
    Kewalo Marine Laboratory, Pacific Biosciences Research Center, University of Hawaii, 41 Ahui Street, Honolulu, Hawaii 96813, USA
    Evodevo 1:8. 2010

Research Grants

Collaborators

Detail Information

Publications68

  1. pmc Cell proliferation is necessary for the regeneration of oral structures in the anthozoan cnidarian Nematostella vectensis
    Yale J Passamaneck
    Kewalo Marine Laboratory, Pacific Biosciences Research Center, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    BMC Dev Biol 12:34. 2012
    ..The present study investigates the pattern of cell proliferation during the regeneration of oral structures and the role of cell proliferation in this process...
  2. pmc Genomic organization, evolution, and expression of photoprotein and opsin genes in Mnemiopsis leidyi: a new view of ctenophore photocytes
    Christine E Schnitzler
    National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
    BMC Biol 10:107. 2012
    ..We combined our genomic survey with gene trees, developmental expression patterns, and functional protein assays of photoproteins and opsins to provide a comprehensive view of light production and light reception in Mnemiopsis...
  3. doi request reprint Evolution of development: the details are in the entrails
    Mark Q Martindale
    Kewalo Marine Laboratory, University of Hawaii, Honolulu, HI 96813, USA
    Curr Biol 23:R25-8. 2013
    ..A recent molecular study, however, challenges long-held views and shows that molecular patterning mechanisms can be used to understand body plan evolution despite variation in gastrulation movements...
  4. pmc Development of the larval anterior neurogenic domains of Terebratalia transversa (Brachiopoda) provides insights into the diversification of larval apical organs and the spiralian nervous system
    Scott Santagata
    Long Island University Post, 720 Northern Blvd, Brookville, NY 11709, USA
    Evodevo 3:3. 2012
    ..abstract:..
  5. pmc Lim homeobox genes in the Ctenophore Mnemiopsis leidyi: the evolution of neural cell type specification
    David K Simmons
    Kewalo Marine Laboratory, Department of Zoology, University of Hawaii at Manoa, Honolulu, HI, USA, 96813
    Evodevo 3:2. 2012
    ..abstract:..
  6. pmc A comparative gene expression database for invertebrates
    Mattias Ormestad
    Kewalo Marine Laboratory, PBRC, University of Hawaii at Manoa, 41, Ahui Street, Honolulu, 96734, HI, USA
    Evodevo 2:17. 2011
    ..abstract:..
  7. pmc Ciliary photoreceptors in the cerebral eyes of a protostome larva
    Yale J Passamaneck
    Kewalo Marine Laboratory, Pacific Biosciences Research Center, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    Evodevo 2:6. 2011
    ..abstract:..
  8. pmc Gene expression in bryozoan larvae suggest a fundamental importance of pre-patterned blastemic cells in the bryozoan life-cycle
    Judith Fuchs
    Kewalo Marine Laboratory, Pacific Biosciences Research Center, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    Evodevo 2:13. 2011
    ..abstract:..
  9. pmc Nuclear receptors from the ctenophore Mnemiopsis leidyi lack a zinc-finger DNA-binding domain: lineage-specific loss or ancestral condition in the emergence of the nuclear receptor superfamily?
    Adam M Reitzel
    Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA, USA
    Evodevo 2:3. 2011
    ..In addition, to gain insight into conserved or novel functions, we examined NR expression during ctenophore development...
  10. pmc A comprehensive fate map by intracellular injection of identified blastomeres in the marine polychaete Capitella teleta
    Néva P Meyer
    Kewalo Marine Laboratory, Pacific Biosciences Research Center, University of Hawaii, 41 Ahui Street, Honolulu, Hawaii 96813, USA
    Evodevo 1:8. 2010
    ..I) develops by spiral cleavage and has been the focus of several recent developmental studies aided by a fully sequenced genome. Fate mapping in polychaetes has lagged behind other spiralian taxa, because of technical limitations...
  11. pmc The homeodomain complement of the ctenophore Mnemiopsis leidyi suggests that Ctenophora and Porifera diverged prior to the ParaHoxozoa
    Joseph F Ryan
    Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
    Evodevo 1:9. 2010
    ..The homeobox superfamily of genes is particularly suited for these kinds of gene content comparisons, since it is large, diverse, and features a highly conserved domain...
  12. pmc A conserved cluster of three PRD-class homeobox genes (homeobrain, rx and orthopedia) in the Cnidaria and Protostomia
    Maureen E Mazza
    Department of Biology, Boston University, 5 Cummington Street, Boston, MA 02215, USA
    Evodevo 1:3. 2010
    ..By contrast, similarly ancient gene clusters have not been reported among the other classes of homeobox genes (that is, the LIM, POU, PRD and SIX classes)...
  13. pmc The evolutionary diversification of LSF and Grainyhead transcription factors preceded the radiation of basal animal lineages
    Nikki Traylor-Knowles
    Department of Biology, Boston University, Boston, Massachusetts 02215, USA
    BMC Evol Biol 10:101. 2010
    ..By contrast, LSF homologs are more widely expressed, and they regulate general cellular functions such as cell cycle progression and survival in addition to cell-lineage specific gene expression...
  14. pmc Coordinated spatial and temporal expression of Hox genes during embryogenesis in the acoel Convolutriloba longifissura
    Andreas Hejnol
    Kewalo Marine Laboratory, PBRC, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    BMC Biol 7:65. 2009
    ..As acoels appear to represent the sister group to the remaining Bilateria (Nephrozoa), investigating Hox gene expression will provide an insight into the ancestral features of the Hox genes in metazoan evolution...
  15. doi request reprint A developmental perspective: changes in the position of the blastopore during bilaterian evolution
    Mark Q Martindale
    Kewalo Marine Laboratory, PBRC, University of Hawaii, 41 Ahui Street, Honolulu, HI, 96813, USA
    Dev Cell 17:162-74. 2009
    ....
  16. pmc Expression and phylogenetic analysis of the zic gene family in the evolution and development of metazoans
    Michael J Layden
    Pacific Biosciences Research Center, Kewalo Marine Laboratory, University of Hawaii, Manoa, 41 Ahui St Honolulu, HI 96813, USA
    Evodevo 1:12. 2010
    ..Prior to this study, the origin of the metazoan zic gene family was unknown and expression of zic gene homologs during the development of early branching metazoans had not been investigated...
  17. pmc Genomic insights into Wnt signaling in an early diverging metazoan, the ctenophore Mnemiopsis leidyi
    Kevin Pang
    Kewalo Marine Laboratory, Pacific Biosciences Research Center, University of Hawaii at Manoa, Honolulu, HI, USA
    Evodevo 1:10. 2010
    ..Genomic data from ctenophores could be particularly relevant, as ctenophores have been proposed to be one of the earliest branching metazoan phyla...
  18. ncbi request reprint The evolution of metazoan axial properties
    Mark Q Martindale
    Kewalo Marine Laboratory, PBRC University of Hawaii, 41 Ahui Street, Honolulu, Hawaii 96813, USA
    Nat Rev Genet 6:917-27. 2005
    ....
  19. ncbi request reprint Investigating the origins of triploblasty: 'mesodermal' gene expression in a diploblastic animal, the sea anemone Nematostella vectensis (phylum, Cnidaria; class, Anthozoa)
    Mark Q Martindale
    Kewalo Marine Laboratory, Pacific Biomedical Research Center, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    Development 131:2463-74. 2004
    ..Alternatively, we consider the possibility that the diploblastic condition of cnidarians is a secondary simplification, derived from an ancestral condition of triploblasty...
  20. ncbi request reprint The Radiata and the evolutionary origins of the bilaterian body plan
    Mark Q Martindale
    Kewalo Marine Lab, University of Hawaii, 41 Ahui St, Honolulu, HI 96813, USA
    Mol Phylogenet Evol 24:358-65. 2002
    ..We briefly review pertinent features of the body plans of the extant radial eumetazoan phyla, the Cnidaria, and Ctenophora, in the context of revealing potential evolutionary links to the bilaterians...
  21. ncbi request reprint Intracellular fate mapping in a basal metazoan, the ctenophore Mnemiopsis leidyi, reveals the origins of mesoderm and the existence of indeterminate cell lineages
    M Q Martindale
    Marine Biological Laboratory, Woods Hole, Massachusetts 02543, USA
    Dev Biol 214:243-57. 1999
    ..The results suggest that mesodermal tissues originally evolved from endoderm tissue...
  22. ncbi request reprint Expression of the ctenophore Brain Factor 1 forkhead gene ortholog (ctenoBF-1) mRNA is restricted to the presumptive mouth and feeding apparatus: implications for axial organization in the Metazoa
    Atsuko Yamada
    Kewalo Marine Laboratory, Pacific Biomedical Research Center, University of Hawaii, Honolulu, 96813, USA
    Dev Genes Evol 212:338-48. 2002
    ..We suggest that the apical organ is not homologous to the brain of bilaterians but that the oral pole of ctenophores corresponds to the anterior pole of bilaterian animals...
  23. ncbi request reprint Reassessing embryogenesis in the Ctenophora: the inductive role of e1 micromeres in organizing ctene row formation in the 'mosaic' embryo, Mnemiopsis leidyi
    M Q Martindale
    Marine Biological Laboratory, Woods Hole, MA 02543, USA
    Development 124:1999-2006. 1997
    ....
  24. pmc The Hedgehog gene family of the cnidarian, Nematostella vectensis, and implications for understanding metazoan Hedgehog pathway evolution
    David Q Matus
    Kewalo Marine Lab University of Hawaii, Honolulu, HI 76813, USA
    Dev Biol 313:501-18. 2008
    ....
  25. doi request reprint Developmental expression of homeobox genes in the ctenophore Mnemiopsis leidyi
    Kevin Pang
    Kewalo Marine Laboratory, Pacific Biosciences Research Center, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    Dev Genes Evol 218:307-19. 2008
    ..We have found that most of these homeobox genes begin expression at gastrulation, and their expression patterns suggest a possible role in patterning of the tentacle apparati and pharynx...
  26. pmc Molecular evidence for deep evolutionary roots of bilaterality in animal development
    David Q Matus
    Kewalo Marine Laboratory, Pacific Bioscience Research Center, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    Proc Natl Acad Sci U S A 103:11195-200. 2006
    ..vectensis could possess antecedents of the organization of the bilaterian central nervous system...
  27. ncbi request reprint Genomic inventory and expression of Sox and Fox genes in the cnidarian Nematostella vectensis
    Craig R Magie
    Kewalo Marine Laboratory, Pacific Biomedical Research Center, University of Hawai i, Honolulu, HI 96813, USA
    Dev Genes Evol 215:618-30. 2005
    ....
  28. doi request reprint Ventralization of an indirect developing hemichordate by NiCl₂ suggests a conserved mechanism of dorso-ventral (D/V) patterning in Ambulacraria (hemichordates and echinoderms)
    E Rottinger
    Kewalo Marine Laboratory, PBRC, University of Hawaii, Honolulu, HI, USA
    Dev Biol 354:173-90. 2011
    ..kowalevskii indicating that a common pathway patterns both larval and adult body plans of the ambulacrarian ancestor and provides insight in to the origin of the chordate body plan...
  29. ncbi request reprint An ancient role for nuclear beta-catenin in the evolution of axial polarity and germ layer segregation
    Athula H Wikramanayake
    Department of Zoology, University of Hawaii at Manoa, 2538 McCarthy Mall, Honolulu 96822, Hawaii
    Nature 426:446-50. 2003
    ....
  30. ncbi request reprint Expression of otd orthologs in the amphipod crustacean, Parhyale hawaiensis
    William E Browne
    Kewalo Marine Lab, Pacific Biosciences Research Center, University of Hawaii, 41 Ahui St, Honolulu, HI 96813, USA
    Dev Genes Evol 216:581-95. 2006
    ..The comparative analysis of otd reveals the divergence of gene expression and gene function associated with duplication of this important developmental gene...
  31. pmc Assessing the root of bilaterian animals with scalable phylogenomic methods
    Andreas Hejnol
    Kewalo Marine Laboratory, University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    Proc Biol Sci 276:4261-70. 2009
    ..The work highlights the implications that these arrangements have for metazoan evolution and permits a clearer picture of ancestral morphologies and life histories in the deep past...
  32. ncbi request reprint A WNT of things to come: evolution of Wnt signaling and polarity in cnidarians
    Patricia N Lee
    Kewalo Marine Lab Pacific Biosciences Research Center, University of Hawaii, 41 Ahui Street, Honolulu, 96813, USA
    Semin Cell Dev Biol 17:157-67. 2006
    ..In this review, we examine what is currently known about Wnt signaling in cnidarians, and discuss what this group of "simple" animals may reveal about the evolution of Wnt signaling and polarity...
  33. ncbi request reprint Protein evolution: structure-function relationships of the oncogene beta-catenin in the evolution of multicellular animals
    Stephan Q Schneider
    Kewalo Marine Laboratory, University of Hawaii at Manao, Honolulu, Hawaii 96813, USA
    J Exp Zool B Mol Dev Evol 295:25-44. 2003
    ....
  34. doi request reprint Acoel development indicates the independent evolution of the bilaterian mouth and anus
    Andreas Hejnol
    Kewalo Marine Laboratory, PBRC, University of Hawaii, 41 Ahui Street, Honolulu, Hawaii 96813, USA
    Nature 456:382-6. 2008
    ..These results contradict the hypothesis that the bilaterian mouth and anus evolved simultaneously from a common blastoporal opening, and suggest that a through gut might have evolved independently in different animal lineages...
  35. ncbi request reprint Regulation and regeneration in the ctenophore Mnemiopsis leidyi
    J Q Henry
    The Marine Biological Laboratory, Woods Hole, Massachusetts 02543, USA
    Dev Biol 227:720-33. 2000
    ..This situation is also contrasted with that of the atentaculate ctenophores, which are unable to undergo post-regeneration...
  36. ncbi request reprint The spatial and temporal expression of Ch-en, the engrailed gene in the polychaete Chaetopterus, does not support a role in body axis segmentation
    E C Seaver
    Kewalo Marine Lab, PBRC University of Hawaii, 41 Ahui Street, Honolulu, Hawaii 96813, USA
    Dev Biol 236:195-209. 2001
    ..We observe banded mesodermal and ectodermal staining in an anterior-posterior sequence in the C region. We do not observe a segment polarity pattern of expression of Ch-en in the ectoderm, as is observed in arthropods...
  37. ncbi request reprint Cephalopod Hox genes and the origin of morphological novelties
    Patricia N Lee
    Department of Zoology, University of Hawaii at Manoa, 2538 McCarthy Mall, Honolulu, Hawaii 96822, USA
    Nature 424:1061-5. 2003
    ....
  38. ncbi request reprint Asymmetric developmental potential along the animal-vegetal axis in the anthozoan cnidarian, Nematostella vectensis, is mediated by Dishevelled
    Patricia N Lee
    Kewalo Marine Lab, Pacific Biosciences Research Center University of Hawaii, 41 Ahui Street, Honolulu, HI 96813, USA
    Dev Biol 310:169-86. 2007
    ....
  39. ncbi request reprint Dorso/ventral genes are asymmetrically expressed and involved in germ-layer demarcation during cnidarian gastrulation
    David Q Matus
    Kewalo Marine Lab, Pacific Bioscience Research Center, University of Hawaii, 41 Ahui Street, Honolulu, Hawaii 96813, USA
    Curr Biol 16:499-505. 2006
    ....
  40. ncbi request reprint Expression of Pax gene family members in the anthozoan cnidarian, Nematostella vectensis
    David Q Matus
    Kewalo Marine Lab, Pacific Bioscience Research Center, University of Hawaii, Honolulu, HI 96813, USA
    Evol Dev 9:25-38. 2007
    ..The results of these patterns are discussed with respect to Pax gene evolution in the Bilateria...
  41. ncbi request reprint Fundamental properties of the spiralian developmental program are displayed by the basal nemertean Carinoma tremaphoros (Palaeonemertea, Nemertea)
    Svetlana A Maslakova
    Kewalo Marine Laboratory, Pacific Biomedical Research Center, University of Hawaii, Honolulu, HI 96813, USA
    Dev Biol 267:342-60. 2004
    ....
  42. ncbi request reprint FGF signaling in gastrulation and neural development in Nematostella vectensis, an anthozoan cnidarian
    David Q Matus
    Kewalo Marine Lab, Pacific Bioscience Research Centre, University of Hawai i, 41 Ahui Street, Honolulu, HI 96813, USA
    Dev Genes Evol 217:137-48. 2007
    ..These results suggest a conserved role for FGF signaling molecules in coordinating both gastrulation and neural induction that predates the Cambrian explosion and the origins of the Bilateria...
  43. pmc Acoel development supports a simple planula-like urbilaterian
    Andreas Hejnol
    Kewalo Marine Laboratory, Pacific Bioscience Research Center, University of Hawaii, Honolulu, HI 96813, USA
    Philos Trans R Soc Lond B Biol Sci 363:1493-501. 2008
    ..We also identify the developmental changes related to gastrulation that gave rise to the urbilaterian from a simpler cnidarian-like ancestor...
  44. ncbi request reprint Inductive interactions and embryonic equivalence groups in a basal metazoan, the ctenophore Mnemiopsis leidyi
    Jonathan Q Henry
    Marine Biological Laboratory, Woods Hole, MA 02543, USA
    Evol Dev 6:17-24. 2004
    ....
  45. doi request reprint The onset of microbial associations in the coral Pocillopora meandrina
    Amy Apprill
    Hawaii Institute of Marine Biology, SOEST, University of Hawaii, Kaneohe, HI, USA
    ISME J 3:685-99. 2009
    ..meandrina appears to occur through horizontal uptake by planulae older than 79 h, and that uptake is preferential to members of the Roseobacter clade and potentially sensitive to the ambient seawater microbial community...
  46. ncbi request reprint High-resolution fate map of the snail Crepidula fornicata: the origins of ciliary bands, nervous system, and muscular elements
    Andreas Hejnol
    University of Hawaii, Kewalo Marine Laboratory, 41 Ahui Street, Honolulu, HI 96813, USA
    Dev Biol 305:63-76. 2007
    ..Our study shows that both first and second velar ciliary bands are generated by the same cells that form the prototroch in other spiralians and apparently bear no homology to the metatroch found in annelids...
  47. ncbi request reprint Gastrulation in the cnidarian Nematostella vectensis occurs via invagination not ingression
    Craig R Magie
    Kewalo Marine Laboratory, Pacific Biomedical Research Center, University of Hawai i Honolulu, HI 96813, USA
    Dev Biol 305:483-97. 2007
    ..These data indicate that EMT is not a major factor during gastrulation in Nematostella...
  48. ncbi request reprint Embryonic development in two species of scleractinian coral embryos: Symbiodinium localization and mode of gastrulation
    Heather Q Marlow
    Kewalo Marine Lab, Pacific Biomedical Research Center, University of Hawaii, 41 Ahui St, Honolulu, HI 96813, USA
    Evol Dev 9:355-67. 2007
    ..This invagination differs from the prawn chip-type gastrulation seen in the complex clade corals and provides evidence for a possible linkage between gastrulation type and phylogenetic history...
  49. pmc Going where traditional markers have not gone before: utility of and promise for RAD sequencing in marine invertebrate phylogeography and population genomics
    A M Reitzel
    Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543, USA
    Mol Ecol 22:2953-70. 2013
    ....
  50. doi request reprint Anatomy and development of the nervous system of Nematostella vectensis, an anthozoan cnidarian
    Heather Q Marlow
    Kewalo Marine Laboratory, Pacific Biomedical Research Center, University of Hawaii, Honolulu, Hawaii 96813, USA
    Dev Neurobiol 69:235-54. 2009
    ..Neural specification in N. vectensis appears to occur through an independent mechanism from that in the classical cnidarian model Hydra...
  51. ncbi request reprint The ancestral role of COE genes may have been in chemoreception: evidence from the development of the sea anemone, Nematostella vectensis (Phylum Cnidaria; Class Anthozoa)
    Kevin Pang
    Kewalo Marine Laboratory, Pacific Biomedical Research Center, University of Hawaii, 41 Ahui St, Honolulu, HI 96813, USA
    Dev Genes Evol 214:134-8. 2004
    ..It is likely that one of the ancestral roles of the COE family of genes may have been in the development of chemosensory neurons...
  52. doi request reprint Broad phylogenomic sampling improves resolution of the animal tree of life
    Casey W Dunn
    Kewalo Marine Laboratory, PBRC, University of Hawaii, 41 Ahui Street, Honolulu, Hawaii 96813, USA
    Nature 452:745-9. 2008
    ..Many relationships between a stable subset of taxa find strong support, and a diminishing number of lineages remain recalcitrant to placement on the tree...
  53. ncbi request reprint Cell-cell adhesion in the cnidaria: insights into the evolution of tissue morphogenesis
    Craig R Magie
    Kewalo Marine Laboratory, Pacific Biomedical Research Center, University of Hawai i Honolulu, Hawaii 96813, USA
    Biol Bull 214:218-32. 2008
    ....
  54. ncbi request reprint Early evolution of a homeobox gene: the parahox gene Gsx in the Cnidaria and the Bilateria
    John R Finnerty
    Biology Department, Boston University, 5 Cummington Street, Boston, MA 02215, USA
    Evol Dev 5:331-45. 2003
    ..Because of the surprisingly high degree of variability in gsx expression within the Cnidaria, it is currently not possible to infer unambiguously the ancestral cnidarian condition or the ancestral eumetazoan condition for gsx expression...
  55. ncbi request reprint Neuroanatomy of sea spiders implies an appendicular origin of the protocerebral segment
    Amy Maxmen
    Department of Organismic and Evolutionary Biology and Museum of Comparative Zoology, Harvard University, 26 Oxford Street, Cambridge, Massachusetts 02138, USA
    Nature 437:1144-8. 2005
    ....
  56. ncbi request reprint vasa and nanos expression patterns in a sea anemone and the evolution of bilaterian germ cell specification mechanisms
    Cassandra G Extavour
    Laboratory for Development and Evolution, Department of Zoology, University of Cambridge, Cambridge, UK
    Evol Dev 7:201-15. 2005
    ..These results suggest one way in which preformation in germ cell development might have evolved from the ancestral epigenetic mechanism that was probably used by a metazoan ancestor...
  57. ncbi request reprint The cell lineage of the polyplacophoran, Chaetopleura apiculata: variation in the spiralian program and implications for molluscan evolution
    Jonathan Q Henry
    Department of Cell and Structural Biology, University of Illinois, Urbana 61801, USA
    Dev Biol 272:145-60. 2004
    ..This study reveals conservation, as well as evolutionary novelty, in the assignment of specific cell fates in the spiralians...
  58. ncbi request reprint Origins of bilateral symmetry: Hox and dpp expression in a sea anemone
    John R Finnerty
    Department of Biology, Boston University, 5 Cummington Street, Boston, MA 02215, USA
    Science 304:1335-7. 2004
    ..These data suggest that bilateral symmetry arose before the evolutionary split of Cnidaria and Bilateria...
  59. ncbi request reprint Cell specification and the role of the polar lobe in the gastropod mollusc Crepidula fornicata
    Jonathan Q Henry
    Department of Cell and Developmental Biology, University of Illinois, Urbana, IL 61801, USA
    Dev Biol 297:295-307. 2006
    ..fornicata follow the mode of development exhibited by equal-cleaving spiralians, which involves conditional specification of the D quadrant organizer via inductive interactions, presumably from the first quartet micromeres...
  60. ncbi request reprint Genomic organization, gene structure, and developmental expression of three clustered otx genes in the sea anemone Nematostella vectensis
    Maureen E Mazza
    Department of Biology, Boston University, Boston, Massachusetts 02215, USA
    J Exp Zool B Mol Dev Evol 308:494-506. 2007
    ..However, the absence of a conserved protein domain in OtxA and OtxC suggests functional evolution of the protein itself...
  61. ncbi request reprint Surprisingly complex T-box gene complement in diploblastic metazoans
    Atsuko Yamada
    Department of Natural History Sciences, Graduate School of Science, Hokkaido University, Kita 10 Nishi 8, Sapporo 060 0810, Japan
    Evol Dev 9:220-30. 2007
    ..Our results from two diploblastic animals indicate that the common ancestor of eumetazoans had a complex set of T-box genes and that two distinct subfamilies might have appeared during triploblastic evolution...
  62. ncbi request reprint Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization
    Nicholas H Putnam
    Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA
    Science 317:86-94. 2007
    ..Analysis of diverse pathways suggests that these gene "inventions" along the lineage leading to animals were likely already well integrated with preexisting eukaryotic genes in the eumetazoan progenitor...
  63. ncbi request reprint Unexpected complexity of the Wnt gene family in a sea anemone
    Arne Kusserow
    Institute of Zoology, Darmstadt University of Technology, Schnittspahnstrasse 10, D 64287 Darmstadt, Germany
    Nature 433:156-60. 2005
    ..It emphasizes the crucial function of Wnt genes in the diversification of eumetazoan body plans...
  64. ncbi request reprint Expression of the 22 nucleotide let-7 heterochronic RNA throughout the Metazoa: a role in life history evolution?
    Amy E Pasquinelli
    Molecular Biology Section, Division of Biology 0368, University of California, San Diego, 9500 Gilman Drive, Bonner Hall, Room 2214, La Jolla, CA 92093 0368, USA
    Evol Dev 5:372-8. 2003
    ..We argue that let-7 is not a bilaterian or triploblast synapomorphy but instead evolved later in metazoan evolution, perhaps in association with complex life history traits...
  65. doi request reprint Beta-catenin is required for the establishment of vegetal embryonic fates in the nemertean, Cerebratulus lacteus
    Jonathan Q Henry
    Department of Cell and Developmental Biology, University of Illinois, 601 S Goodwin Ave, Urbana, IL 61801, USA
    Dev Biol 317:368-79. 2008
    ..lacteus. However, unlike the case found in polychaete annelid and soil nematode embryos, there is no evidence for a role of beta-catenin in regulating cell fates and asymmetric cell divisions along the entire anterior-posterior axis...
  66. ncbi request reprint Broad taxon and gene sampling indicate that chaetognaths are protostomes
    David Q Matus
    Curr Biol 16:R575-6. 2006
  67. ncbi request reprint The evolutionary origin of hedgehog proteins
    Maja Adamska
    School of Integrative Biology, The University of Queensland, Brisbane Queensland 4072, Australia
    Curr Biol 17:R836-7. 2007
  68. ncbi request reprint The origin of mesoderm in phoronids
    Gary Freeman
    Friday Harbor Laboratories, University of Washington
    Dev Biol 252:301-11. 2002
    ..These marking experiments also confirmed the observation that nerve cells originate both from the apical organ and the trunk region and show for the first time that the intestine originates by ingression of posterior ectoderm...

Research Grants3

  1. Functional Genomics in a Simple Model Metazoan
    MARK MARTINDALE; Fiscal Year: 2007
    ....
  2. Gene regulatory network evolution and the origin of biological novelties
    Mark Q Martindale; Fiscal Year: 2010
    ..These novel data will provide insight into the significance of variations in the GRNs in different systems and suggest specific gene interactions involved in abnormalities in endomesodermal development. ..