Laura F Martin

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi request reprint Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia
    Laura F Martin
    Department of Psychiatry, Department of Veterans Affairs and University of Colorado Health Sciences Center, 4200 East Ninth Avenue, C268 71, Denver, CO 80262, USA
    Psychopharmacology (Berl) 174:54-64. 2004
  2. doi request reprint Nicotine enhances automatic temporal processing as measured by the mismatch negativity waveform
    Laura F Martin
    Research Service, Denver Veterans Affairs Medical Center, Department of Psychiatry, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, C268 71, Denver, CO 80262, USA
    Nicotine Tob Res 11:698-706. 2009
  3. ncbi request reprint Physiology of schizophrenia, bipolar disorder, and schizoaffective disorder
    Laura F Martin
    Department of Psychiatry, University of Colorado at Denver and Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Am J Psychiatry 164:1900-6. 2007
  4. pmc Sensory gating and alpha-7 nicotinic receptor gene allelic variants in schizoaffective disorder, bipolar type
    Laura F Martin
    Department of Psychiatry, Denver Veterans Affairs Medical Center, Denver, Colorado 80262, USA
    Am J Med Genet B Neuropsychiatr Genet 144:611-4. 2007
  5. pmc Effects of an alpha 7-nicotinic agonist on default network activity in schizophrenia
    Jason R Tregellas
    Department of Psychiatry, Denver VA Medical Center, VISN19 MIRECC, Colorado, USA
    Biol Psychiatry 69:7-11. 2011
  6. pmc Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia
    Jason R Tregellas
    Department of Psychiatry, Denver VA Medical Center VISN19 MIRECC and University of Colorado Denver, Aurora, CO 80045, USA
    Neuropsychopharmacology 35:938-42. 2010
  7. ncbi request reprint Effects of nicotine on hippocampal and cingulate activity during smooth pursuit eye movement in schizophrenia
    Jody Tanabe
    Department of Radiology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Biol Psychiatry 59:754-61. 2006
  8. pmc Nicotine increases brain functional network efficiency
    Korey P Wylie
    Department of Psychiatry, University of Colorado Anschutz Medical Campus, Bldg 500, Mail Stop F546, 13001 East 17th Place, Aurora, CO 80045, USA
    Neuroimage 63:73-80. 2012
  9. pmc Initial phase 2 trial of a nicotinic agonist in schizophrenia
    Robert Freedman
    Department of Psychiatry, Denver VA Medical Center and University of Colorado, Denver, CO 80262, USA
    Am J Psychiatry 165:1040-7. 2008
  10. ncbi request reprint FMRI of response to nicotine during a smooth pursuit eye movement task in schizophrenia
    Jason R Tregellas
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Psychiatry 162:391-3. 2005

Detail Information

Publications13

  1. ncbi request reprint Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia
    Laura F Martin
    Department of Psychiatry, Department of Veterans Affairs and University of Colorado Health Sciences Center, 4200 East Ninth Avenue, C268 71, Denver, CO 80262, USA
    Psychopharmacology (Berl) 174:54-64. 2004
    ..This inhibitory process, which involves the alpha(7) nicotinic receptor mediated release of gamma-aminobutyric acid (GABA) by hippocampal interneurons, represents a potential new target for therapeutic intervention in schizophrenia...
  2. doi request reprint Nicotine enhances automatic temporal processing as measured by the mismatch negativity waveform
    Laura F Martin
    Research Service, Denver Veterans Affairs Medical Center, Department of Psychiatry, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, C268 71, Denver, CO 80262, USA
    Nicotine Tob Res 11:698-706. 2009
    ..Mismatch negativity (MMN) has been used as a physiological measure of automatic temporal processing to avoid this potential confound...
  3. ncbi request reprint Physiology of schizophrenia, bipolar disorder, and schizoaffective disorder
    Laura F Martin
    Department of Psychiatry, University of Colorado at Denver and Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Am J Psychiatry 164:1900-6. 2007
    ..A second aim was to determine whether subjects with schizoaffective disorder, bipolar type, were neurophysiologically more similar to subjects with schizophrenia or subjects with bipolar disorder...
  4. pmc Sensory gating and alpha-7 nicotinic receptor gene allelic variants in schizoaffective disorder, bipolar type
    Laura F Martin
    Department of Psychiatry, Denver Veterans Affairs Medical Center, Denver, Colorado 80262, USA
    Am J Med Genet B Neuropsychiatr Genet 144:611-4. 2007
    ..The purpose of this study was to determine if CHRNA7 promoter allelic variants are also associated with abnormal P50 ratios in persons with schizoaffective disorder, bipolar type...
  5. pmc Effects of an alpha 7-nicotinic agonist on default network activity in schizophrenia
    Jason R Tregellas
    Department of Psychiatry, Denver VA Medical Center, VISN19 MIRECC, Colorado, USA
    Biol Psychiatry 69:7-11. 2011
    ..This study examined the effects of DMXB-A on default network activity as a biomarker for drug effects on pathologic brain function associated with schizophrenia...
  6. pmc Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia
    Jason R Tregellas
    Department of Psychiatry, Denver VA Medical Center VISN19 MIRECC and University of Colorado Denver, Aurora, CO 80045, USA
    Neuropsychopharmacology 35:938-42. 2010
    ..Imaging of drug response is useful in planning future clinical tests of this compound and other nicotinic agonists for schizophrenia...
  7. ncbi request reprint Effects of nicotine on hippocampal and cingulate activity during smooth pursuit eye movement in schizophrenia
    Jody Tanabe
    Department of Radiology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Biol Psychiatry 59:754-61. 2006
    ..The purpose of this work was to determine if nicotine differentially affects brain activity in schizophrenic and control subjects during pursuit eye tracking...
  8. pmc Nicotine increases brain functional network efficiency
    Korey P Wylie
    Department of Psychiatry, University of Colorado Anschutz Medical Campus, Bldg 500, Mail Stop F546, 13001 East 17th Place, Aurora, CO 80045, USA
    Neuroimage 63:73-80. 2012
    ..These changes in network topology may be one mechanism by which cholinergic therapies improve brain function...
  9. pmc Initial phase 2 trial of a nicotinic agonist in schizophrenia
    Robert Freedman
    Department of Psychiatry, Denver VA Medical Center and University of Colorado, Denver, CO 80262, USA
    Am J Psychiatry 165:1040-7. 2008
    ..The agent 3-(2,4-dimethoxybenzylidene) anabaseine (DMXB-A) is a partial alpha(7)-nicotinic agonist and can be taken orally. A phase 1 trial showed evidence for cognitive enhancement in schizophrenia...
  10. ncbi request reprint FMRI of response to nicotine during a smooth pursuit eye movement task in schizophrenia
    Jason R Tregellas
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Psychiatry 162:391-3. 2005
    ..This study used functional magnetic resonance imaging (fMRI) to examine changes in brain hemodynamic response associated with nicotine administration during a smooth pursuit eye movement task in subjects with schizophrenia...
  11. ncbi request reprint Schizophrenia and the alpha7 nicotinic acetylcholine receptor
    Laura F Martin
    Research Service, VA Eastern Colorado Health Care System, Denver, Colorado 80220, USA
    Int Rev Neurobiol 78:225-46. 2007
    ..alpha7 Nicotinic acetylcholine receptor agonists appear to be viable candidates for the treatment of cognitive disturbances in schizophrenia...
  12. ncbi request reprint Gray matter volume differences and the effects of smoking on gray matter in schizophrenia
    Jason R Tregellas
    Research Service, Denver VA Medical Center, Denver, Colorado, USA
    Schizophr Res 97:242-9. 2007
    ..The present study used voxel-based morphometry (VBM) to examine differences in gray matter in subjects with schizophrenia and evaluate the effects of smoking on this measure...
  13. pmc Nicotine effects on default mode network during resting state
    Jody Tanabe
    Department of Radiology, University of Colorado Denver School of Medicine, Denver, CO, USA
    Psychopharmacology (Berl) 216:287-95. 2011
    ..It is unknown if these pharmacological effects also occur in the absence of effortful processing...