Research Topics
Genomes and GenesSpecies | Daniel MarsonSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Publications
Clinical and ethical aspects of financial capacity in dementia: a commentaryDaniel C Marson
Department of Neurology and Alzheimer s Disease Center, University of Alabama at Birmingham Electronic address
Am J Geriatr Psychiatry 21:382-90. 2013..The ultimate goal of the article is to focus clinical and ethical attention on a neglected capacity that is of fundamental importance for patients, families, and healthcare and legal professionals...
Treatment consent capacity in patients with traumatic brain injury across a range of injury severityK L Triebel
Department of Neurology, Division of Neuropsychology, University of Alabama at Birmingham, Birmingham, USA
Neurology 78:1472-8. 2012..To investigate medical decision-making capacity (MDC) in patients with acute traumatic brain injury (TBI) across a range of injury severity...
Capacity to consent to research participation in adults with malignant gliomaDaniel C Marson
Divisions of Neuropsychology and Neuro oncology, University of Alabama at Birmingham, Birmingham, AL 35294 0017, USA
J Clin Oncol 28:3844-50. 2010..To investigate research consent capacity (RCC) in patients with malignant gliomas (MGs) and identify cognitive abilities and clinical factors associated with RCC in MG...
Clinical interview assessment of financial capacity in older adults with mild cognitive impairment and Alzheimer's diseaseDaniel C Marson
Department of Neurology, SC 650, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Am Geriatr Soc 57:806-14. 2009..To investigate financial capacity in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) using a clinician interview approach...
Assessing financial capacity in patients with Alzheimer disease: A conceptual model and prototype instrumentD C Marson
Department of Neurology, University of Alabama at Birmingham School of Medicine, 625 19th St S, 1216 Jefferson Tower, Birmingham, AL 35233 7340, USA
Arch Neurol 57:877-84. 2000..To investigate financial capacity in patients with Alzheimer disease (AD) using a new theoretical model and prototype psychometric instrument...
Financial capacity in persons with schizophrenia and serious mental illness: clinical and research ethics aspectsDaniel C Marson
Department of Neurology, Room JT1216, University of Alabama at Birmingham, Birmingham, AL 35233 7340, USA
Schizophr Bull 32:81-91. 2006..The ultimate goal of this article is to focus clinical and ethical attention on a neglected decisional capacity in SMI that is of fundamental importance for clients, families, clinicians, and researchers...
Declining financial capacity in mild cognitive impairment: A 1-year longitudinal studyK L Triebel
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35294 0017, USA
Neurology 73:928-34. 2009..To investigate 1-year change in financial capacity in relation to conversion from amnestic mild cognitive impairment (MCI) to dementia...
A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderlyApril J Ho
Laboratory of Neuroimaging, Department of Neurology, University of California School of Medicine, Los Angeles, CA 90095, USA
Proc Natl Acad Sci U S A 107:8404-9. 2010..These brain maps reveal that a commonly carried susceptibility allele for obesity is associated with structural brain atrophy, with implications for the health of the elderly...
Medical decision-making capacity in patients with malignant gliomaKristen L Triebel
Department of Neurology, Division of Neuropsychology, University of Alabama at Birmingham, AL 35294 0017, USA
Neurology 73:2086-92. 2009..We prospectively assessed medical decision-making capacity (MDC) in patients with MG using a standardized psychometric instrument...
Neurocognitive predictors of financial capacity across the dementia spectrum: Normal aging, mild cognitive impairment, and Alzheimer's diseaseMegan G Sherod
Department of Neurology, University of Alabama at Birmingham, 35294 0017, USA
J Int Neuropsychol Soc 15:258-67. 2009..Executive function and verbal memory were secondary model predictors. The results offer insight into the cognitive basis of financial capacity across the dementia spectrum of cognitive aging, MCI, and AD...
Medical decision-making capacity in cognitively impaired Parkinson's disease patients without dementiaRoy C Martin
Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0017, USA
Mov Disord 23:1867-74. 2008..Clinicians and researchers should carefully assess decisional capacity in all patients with PD with cognitive impairment...
Declining medical decision-making capacity in mild AD: a two-year longitudinal studyJustin S Huthwaite
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35233-7340, USA
Behav Sci Law 24:453-63. 2006..Capacity outcome data reflect similar declines over time for these four consent standards. The findings suggest the value of early assessment and regular monitoring at two-year intervals of MDC in patients with mild AD...
Medical decision-making abilities in older adults with chronic partial epilepsyJennifer K Bambara
Department of Psychology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
Epilepsy Behav 10:63-8. 2007..Physicians should consider the decisional abilities of their older adult patients with epilepsy when presenting treatment options...
Awareness of deficits in financial abilities in patients with mild cognitive impairment: going beyond self-informant discrepancyOzioma C Okonkwo
Department of Psychology, University of Alabama at Birmingham, Birmingham, AL 35294 0017, USA
Am J Geriatr Psychiatry 16:650-9. 2008..In this study, the authors used three different approaches to examine accuracy of self-report of financial abilities among patients with MCI...
Declining financial capacity in patients with mild Alzheimer disease: a one-year longitudinal studyRoy Martin
Department of Neurology and Alzheimer s Disease Research Center, University of Alabama at Birmingham, and VA Medical Center, Birmingham, AL 35294 0017, USA
Am J Geriatr Psychiatry 16:209-19. 2008..The objective of this study was to investigate change over time in financial abilities in patients with mild Alzheimer disease (AD)...
Older adults with epilepsy demonstrate cognitive impairments compared with patients with amnestic mild cognitive impairmentH Randall Griffith
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
Epilepsy Behav 8:161-8. 2006..This study emphasizes the clinical importance of cognitive impairment in seniors with epilepsy and highlights the need for future studies addressing causes and treatment of cognitive impairment...
Amnestic mild cognitive impairment: diagnostic outcomes and clinical prediction over a two-year time periodH Randall Griffith
Department of Neurology, University of Alabama at Birmingham, 1216 Jefferson Tower, 625 19th Street South, Birmingham, AL, USA
J Int Neuropsychol Soc 12:166-75. 2006..Such methods could aid in identifying MCI patients who might benefit from early treatment, in providing prognostic information to patients, and identifying potential clinical trial participants...
Magnetic resonance imaging volume of the angular gyri predicts financial skill deficits in people with amnestic mild cognitive impairmentH Randall Griffith
Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Am Geriatr Soc 58:265-74. 2010..To better understand how brain atrophy in amnestic mild cognitive impairment (MCI) as measured using magnetic resonance imaging (MRI) volumetrics could affect instrumental activities of daily living (IADLs) such as financial abilities...
Cognitive correlates of financial abilities in mild cognitive impairmentOzioma C Okonkwo
Department of Psychology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
J Am Geriatr Soc 54:1745-50. 2006..To investigate the cognitive correlates of financial abilities in mild cognitive impairment (MCI)...
Atypical Hallervorden-Spatz disease with preserved cognition and obtrusive obsessions and compulsionsAnthony P Nicholas
Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35249 7340, USA
Mov Disord 20:880-6. 2005..This case demonstrates that HSD patients who survive into middle age should not be assumed to have a progressive dementia. In such cases, atypical behavioral problems such as persistent obsessions and compulsions may be present instead...
Executive function is associated with brain proton magnetic resonance spectroscopy in amnestic mild cognitive impairmentH Randall Griffith
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA
J Clin Exp Neuropsychol 29:599-609. 2007..This finding suggests a role for the posterior cingulate in executive function in MCI. Proton MRS may offer a means to track neurometabolic changes associated with cognitive impairment in MCI...
Loss of calculation abilities in patients with mild and moderate Alzheimer diseaseRoy C Martin
Department of Neurology, Alzheimer's Disease Research Center, Center for Aging, University of Alabama, Birmingham, AL 35233, USA
Arch Neurol 60:1585-9. 2003..These findings suggest that loss of calculation abilities in AD is both hierarchical (by arithmetic operation) and a function of disease severity...
Self- and informant report of financial abilities in patients with Alzheimer's disease: reliable and valid?Virginia G Wadley
Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
J Am Geriatr Soc 51:1621-6. 2003..To evaluate the consistency, stability, and accuracy of reports by patients with Alzheimer's disease (AD) and their caregivers regarding the patients' premorbid and current financial abilities...
Brain metabolic correlates of decision making in amnestic mild cognitive impairmentH Randall Griffith
Departments of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 17:492-504. 2010..46, p < .05). The relationship of NAA/Cr with decision-making suggests a role for posterior cortical neuronal functioning in performance of complex IADLs in MCI...
Voxelwise genome-wide association study (vGWAS)Jason L Stein
Laboratory of Neuro Imaging, Department of Neurology, University of California, Los Angeles School of Medicine, Neuroscience Research Building 225E, 635 Charles Young Drive, Los Angeles, CA 90095 1769, USA
Neuroimage 53:1160-74. 2010..These genes have high relevance to brain structure. This is the first voxelwise genome wide association study to our knowledge, and offers a novel method to discover genetic influences on brain structure...
Cognitive functioning over 3 years in community dwelling older adults with chronic partial epilepsyH Randall Griffith
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35233, United States
Epilepsy Res 74:91-6. 2007..A failure to benefit from repeat exposure to a Delayed Recall task could indicate learning deficits. These patients may also progressively lose executive control, possibly as a result of accelerated aging...
Impairment and partial recovery of medical decision-making capacity in traumatic brain injury: a 6-month longitudinal studyDaniel C Marson
Department of Neurology, University of Alabama, Birmingham, AL, USA
Arch Phys Med Rehabil 86:889-95. 2005..The study suggests the importance in the rehabilitation setting of serial evaluations of MDC in patients with TBI...
Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer's diseaseDavid A Wolk
Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104, USA
Proc Natl Acad Sci U S A 107:10256-61. 2010....
Elevated brain scyllo-inositol concentrations in patients with Alzheimer's diseaseH Randall Griffith
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA
NMR Biomed 20:709-16. 2007..Further research on the mechanisms of sI increase in AD is needed. Future studies on the longitudinal course of sI/Cr in MCI and AD appear warranted...
Brain metabolism differs in Alzheimer's disease and Parkinson's disease dementiaH Randall Griffith
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA
Alzheimers Dement 4:421-7. 2008..We compared brain metabolic abnormalities in Alzheimer's disease (AD) and in Parkinson's disease with dementia (PDD) as measured by proton magnetic resonance spectroscopy (MRS)...
Brain N-acetylaspartate is reduced in Parkinson disease with dementiaHenry Randall Griffith
Department of Neurology, Alzheimer s Disease Research Center, University of Alabama at Birmingham, Birmingham, AL, USA
Alzheimer Dis Assoc Disord 22:54-60. 2008..Future studies investigating the utility of brain MRS as a predictor of dementia in PD and comparing brain metabolism in PDD with other dementias seem warranted...
Empirical studies of capacity in older adults: finding clarity amidst complexityDaniel C Marson
J Gerontol B Psychol Sci Soc Sci 62:P18-9. 2007
Assessment of decision-making capacity in older adults: an emerging area of practice and researchJennifer Moye
VA Boston Healthcare System, Brockton Campus, 940 Belmont Street, Brockton, MA 02301, USA
J Gerontol B Psychol Sci Soc Sci 62:P3-P11. 2007....
Research Grants
- Functional Change in Mild Cognitive ImpairmentDaniel C Marson; Fiscal Year: 2010....
- Medical Decision-Making Capacity in Traumatic Brain InjuryDaniel C Marson; Fiscal Year: 2010..Aim 2 will test cross- sectional and longitudinal cognitive models of MDC in TBI patients, and identify cognitive markers of MDC in TBI. ..
- Medical Decision-Making Capacity in Traumatic Brain InjuryDaniel Marson; Fiscal Year: 2009..Aim 2 will test cross- sectional and longitudinal cognitive models of MDC in TBI patients, and identify cognitive markers of MDC in TBI. ..
- ALZHEIMER'S DISEASE RESEARCH CENTERDaniel Marson; Fiscal Year: 2007..Continuation of an ADRC at UAB would allow us to continue both clinical and basic research efforts in AD and would allow us to expand into new research areas (e.g. PDD, MCI). ..
- Functional Change in Mild Cognitive ImpairmentDaniel Marson; Fiscal Year: 2007..This study will begin to address a key gap in the scientific and clinical understanding of MCI. ..
- Medical Decision-Making Capacity in Traumatic Brain InjuryDaniel Marson; Fiscal Year: 2007..Aim 2 will test cross- sectional and longitudinal cognitive models of MDC in TBI patients, and identify cognitive markers of MDC in TBI. ..
- FINANCIAL CAPACITY IN ALZHEIMERS DISEASEDaniel Marson; Fiscal Year: 2002..In Aim 2, we will clinically investigate domain specific financial capacities in AD patients using physician judgments, the ..
