Research Topics
| JOHN FOSTER MARSHALLSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
D2 antagonist-induced c-fos in an identified subpopulation of globus pallidus neurons by a direct intrapallidal actionLauren M Billings
Department of Neurobiology and Behavior, 2205 McGaugh Hall, University of California at Irvine, Irvine, CA 92697 4550, USA
Brain Res 964:237-43. 2003....
Methamphetamine influences on brain and behavior: unsafe at any speed?John F Marshall
Department of Neurobiology and Behavior, Center for Neurobiology of Learning and Memory, University of California, Irvine, CA 92697, USA
Trends Neurosci 35:536-45. 2012....- Methamphetamine-induced neural and cognitive changes in rodentsJohn F Marshall
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697 4550, USA
Addiction 102:61-9. 2007..The purpose of these experiments is to develop animal models to understand the long-lasting influences of methamphetamine exposure on cerebral cortex and cognitive function... - The role of the globus pallidus D2 subfamily of dopamine receptors in pallidal immediate early gene expressionJ F Marshall
Department of Neurobiology and Behavior, 2215 Bio Sci II, University of California, Irvine, CA 92697 4550, USA
Neuroscience 105:365-78. 2001..These results strongly suggest that the dopaminergic innervation of globus pallidus, acting through D2-like receptors internal to this structure, can control gene expression in pallidal neurons... - A sensitizing regimen of methamphetamine causes impairments in a novelty preference task of object recognitionAnnabelle M Belcher
Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA
Behav Brain Res 170:167-72. 2006..This study supports the conclusion that factors other than monoamine terminal injury contribute to the methamphetamine-induced cognitive impairments... 
A neurotoxic regimen of methamphetamine impairs novelty recognition as measured by a social odor-based taskSteven J O'Dell
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, United States
Behav Brain Res 216:396-401. 2011..As compared with previously employed object recognition tasks, this test may be advantageous for investigating mAMPH-induced memory impairments in rodents...- Effects of vibrissae removal on methamphetamine-induced damage to rat somatosensory cortical neuronsSteven J O'Dell
Department of Neurobiology and Behavior, University of California, Irvine, California 92697, USA
Synapse 43:122-30. 2002..Thus, some of the injurious effects of drugs may depend on afferent activity occurring as a result of the abnormal behaviors evoked by their administration... - Neurotoxic regimens of methamphetamine induce persistent expression of phospho-c-Jun in somatosensory cortex and substantia nigraSteven J O'Dell
Department of Neurobiology and Behavior, University of California, Irvine, California 92697, USA
Synapse 55:137-47. 2005..Since phospho-c-Jun indicates activation of Jun N-terminal kinase pathways, which have been implicated in apoptosis, we conclude that phospho-c-Jun provides a useful new marker for mAMPH-induced damage to cortical neurons... - Methamphetamine influences on recognition memory: comparison of escalating and single-day dosing regimensAnnabelle M Belcher
Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 4550, USA
Neuropsychopharmacology 33:1453-63. 2008..In aggregate, these findings suggest a correspondence between mAMPH-induced monoaminergic injury and the resulting OR deficits... - A sensitizing d-amphetamine regimen induces long-lasting spinophilin protein upregulation in the rat striatum and limbic forebrainSteven R Boikess
Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA 92697 4550, USA
Eur J Neurosci 28:2099-107. 2008..Radioimmunocytochemistry for spinophilin provides a novel approach to identification of brain regions whose neurons undergo dendritic change after chronic exposure to drugs of abuse... - Impaired object recognition memory following methamphetamine, but not p-chloroamphetamine- or d-amphetamine-induced neurotoxicityAnnabelle M Belcher
1Department of Neurobiology and Behavior, University of California, Irvine, CA, USA
Neuropsychopharmacology 30:2026-34. 2005..This pattern of results indicates that no single feature of mAMPH-induced neurotoxicity is sufficient to produce the OR impairments seen after mAMPH treatment... - Glutamic acid decarboxylase 67 mRNA regulation in two globus pallidus neuron populations by dopamine and the subthalamic nucleusLauren M Billings
Department of Neurobiology and Behavior, University of California, Irvine, California 92627 4550, USA
J Neurosci 24:3094-103. 2004..This pattern of results has implications for pallidal control of striatal versus downstream basal ganglia nuclei... - Long-term changes in dopamine-stimulated gene expression after single-day methamphetamine exposureAnnabelle M Belcher
Department of Neurobiology and Behavior, University of California, Irvine, California 92697, USA
Synapse 63:403-12. 2009..This study demonstrates the profound and enduring effects of mAMPH administration on dopamine-stimulated cortical function in animals... - Altered Fos expression in neural pathways underlying cue-elicited drug seeking in the ratCourtney A Miller
Department of Neurobiology and Behaviour, University of California, Irvine, USA
Eur J Neurosci 21:1385-93. 2005..Our findings support the view that the BLC, rather than the PrL, provides significant excitatory driving to the NAcc during cue-elicited drug seeking... - Altered prelimbic cortex output during cue-elicited drug seekingCourtney A Miller
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697, USA
J Neurosci 24:6889-97. 2004..These results suggest a shifting prefrontal cortex cell population response during cocaine-seeking... - A sensitizing D-amphetamine dose regimen induces long-lasting spinophilin and VGLUT1 protein upregulation in the rat diencephalonSteven R Boikess
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697, USA
Neurosci Lett 469:49-54. 2010..Moreover, they suggest that D-AMPH-induced synaptic changes may occur preferentially in excitatory synapses... - Molecular, chemical, and anatomical characterization of globus pallidus dopamine D2 receptor mRNA-containing neuronsBrian R Hoover
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
Synapse 52:100-13. 2004..These results reveal heterogeneous chemical and anatomical properties of the extensive population of D2+ GP neurons, a potential cellular substrate for dopamine's effects in pallidum... - Neurotoxic methamphetamine regimen severely impairs recognition memory in ratsNadja Schroder
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697, USA
Synapse 49:89-96. 2003..Thus, administration of mAMPH restricted to a single day can produce a profound, persistent, and selective deficit in a nonspatial hippocampus-dependent memory... - Reduction of TSG101 protein has a negative impact on tumor cell growthGang Zhu
Richard Dimbleby Department of Cancer Research Cancer Research U K Laboratory, GKT School of Medicine, St Thomas Hospital, London, United Kingdom
Int J Cancer 109:541-7. 2004..5%). These results show that the TSG101 gene does not comply with the usual characteristics of a tumor-suppressor gene; rather, its expression may be necessary for activities associated with aspects of tumor progression... - alpha vbeta 6 Integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulationDaniel Marsh
Centre for Tumour Biology, Institute of Cancer, The London School of Medicine and Dentistry, London, United Kingdom
Cancer Res 68:3295-303. 2008..These data suggest that alpha v beta 6-dependent transforming growth factor-beta1 activation induces both the infiltrative growth pattern and fibrotic stroma so characteristic of morphoeic BCC... - HS1-associated protein X-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin alphavbeta6Alan G Ramsay
Centre for Tumour Biology, Institute of Cancer and Cancer Research UK Clinical Centre, London, United Kingdom
Cancer Res 67:5275-84. 2007..This report establishes that integrin endocytosis is required for alphavbeta6-dependent carcinoma cell motility and invasion and suggests that this process is an important mechanism in cancer progression... - Dopamine manipulation alters immediate-early gene response of striatal parvalbumin interneurons to cortical stimulationJennifer T Trevitt
Psychology Department, California State University, Fullerton, 92631, USA
Brain Res 1035:41-50. 2005..Taken together, these results indicate that DA may importantly control striatal output via influences on PV-ir interneurons. Possible mechanisms for these influences are discussed... - Combination of microdissection and microarray analysis to identify gene expression changes between differentially located tumour cells in breast cancerGang Zhu
Richard Dimbleby Department of Cancer Research/Cancer Research UK Laboratory, GKT School of Medicine, St Thomas' Hospital, London, UK
Oncogene 22:3742-8. 2003..Thus, changes in gene expression associated with variation in microanatomical location of neoplastic cells can be detected within even small developing tumour masses...
Research Grants
- STRIATAL ORGANIZATION AND DOPAMINE RECEPTOR LOCALIZATIONJohn Marshall; Fiscal Year: 1991..Also, using [14 C]2-deoxyglucose autoradiography to chart the influences on basal gangliar metabolism, the effects of dopamine D 1 and D 2 agonists in the substantia nigra will be compared...
- STRIATAL ORGANIZATION AND DOPAMINE RECEPTOR LOCALIZATIONJohn Marshall; Fiscal Year: 2000..These experiments are intended to elucidate the processes underlying the supersensitivity to dopamine and its agonists that occurs after dopaminergic denervation. ..
- METHAMPHETAMINE ABUSE AND CORTICAL CELL INJURYJohn Marshall; Fiscal Year: 2001....
- METHAMPHETAMINE ABUSE AND CORTICAL CELL INJURYJohn Marshall; Fiscal Year: 2006....
- STRIATAL ORGANIZATION AND DOPAMINE RECEPTOR LOCALIZATIONJohn Marshall; Fiscal Year: 2006..The significance of this work derives both from its relevance to basal ganglia disorders such as Parkinson's disease and also because of its potential to elucidate the significance of the pallidostriatal circuitry. ..
- ERK Signaling, Neural Circuits and Reconsolidation of Cocaine-Cue MemoriesJohn Marshall; Fiscal Year: 2007..Relevance. A greater understanding of the neurobiology of reconsolidation of drug-cue memories holds the potential to provide new avenues for preventing relapse into substance abuse among the addicted population. ..
- METHAMPHETAMINE ABUSE AND CORTICAL CELL INJURYJohn Marshall; Fiscal Year: 2009..Using rats, we are studying how the brain damage caused by methamphetamine abuse occurs and might cause memory problems. Our goal is to discover information useful in preventing or repairing this cognitive decline. ..
- METHAMPHETAMINE ABUSE AND CORTICAL CELL INJURYJOHN FOSTER MARSHALL; Fiscal Year: 2010..Using rats, we are studying how the brain damage caused by methamphetamine abuse occurs and might cause memory problems. Our goal is to discover information useful in preventing or repairing this cognitive decline. ..
- ERK Signaling, Neural Circuits and Reconsolidation of Cocaine-Cue MemoriesJOHN FOSTER MARSHALL; Fiscal Year: 2010..Relevance. A greater understanding of the neurobiology of reconsolidation of drug-cue memories holds the potential to provide new avenues for preventing relapse into substance abuse among the addicted population. ..