Marshall J, Van Devender E. Synthesis of (-)-deoxypukalide, the enantiomer of a degradation product of the furanocembranolide pukalide. J Org Chem. 2001;66:8037-41 pubmed
..The synthetic strategy was strongly directed by molecular mechanics calculations, which provided valuable insight into stereodefining steps including double bond stereochemistry and butenolide configuration. ..