Todd P Margolis

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency
    William P Halford
    Dept of Veterinary Molecular Biology, Montana State University, Bozeman, MT, USA
    Virol J 3:44. 2006
  2. pmc CMV retinitis screening and treatment in a resource-poor setting: three-year experience from a primary care HIV/AIDS programme in Myanmar
    Nini Tun
    California Pacific Medical Center, San Francisco, USA
    J Int AIDS Soc 14:41. 2011
  3. pmc Spontaneous reactivation of herpes simplex virus type 1 in latently infected murine sensory ganglia
    Todd P Margolis
    Francis I Proctor Foundation, UCSF, Medical Sciences Building S 310, 513 Parnassus Ave, San Francisco, CA 94143 0412, USA
    J Virol 81:11069-74. 2007
  4. ncbi request reprint Fusarium--A new culprit in the contact lens case
    Todd P Margolis
    JAMA 296:985-7. 2006
  5. pmc Herpes simplex virus type 2 (HSV-2) establishes latent infection in a different population of ganglionic neurons than HSV-1: role of latency-associated transcripts
    Todd P Margolis
    F I Proctor Foundation, University of California, San Francisco, San Francisco, CA 94143, USA
    J Virol 81:1872-8. 2007
  6. ncbi request reprint "Steel wool keratopathy": a clinical sign of chronic inflammation
    Gerami D Seitzman
    Francis I Proctor Foundation and Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USA
    Cornea 25:742-4. 2006
  7. pmc Practice patterns and opinions in the management of recurrent or chronic herpes zoster ophthalmicus
    Aileen Sy
    Department of Ophthalmology, F I Proctor Foundation, University of California, San Francisco, San Francisco, CA, USA
    Cornea 31:786-90. 2012
  8. pmc The clinical differentiation of bacterial and fungal keratitis: a photographic survey
    Cyril Dalmon
    F I Proctor Foundation and Department of Ophthalmology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
    Invest Ophthalmol Vis Sci 53:1787-91. 2012
  9. ncbi request reprint Correlation between clinical suspicion and polymerase chain reaction verification of infectious vitritis
    Nisha Acharya
    Proctor Foundation, Department of Ophthalmology, University of California San Francisco, 95 Kirkham Street, San Francisco, CA 94143, USA
    Am J Ophthalmol 141:584-5. 2006
  10. doi request reprint Epidemiology of ulcerative keratitis in Northern California
    Bennie H Jeng
    Department of Ophthalmology, University of California, San Francisco, USA
    Arch Ophthalmol 128:1022-8. 2010

Collaborators

Detail Information

Publications40

  1. pmc ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency
    William P Halford
    Dept of Veterinary Molecular Biology, Montana State University, Bozeman, MT, USA
    Virol J 3:44. 2006
    ....
  2. pmc CMV retinitis screening and treatment in a resource-poor setting: three-year experience from a primary care HIV/AIDS programme in Myanmar
    Nini Tun
    California Pacific Medical Center, San Francisco, USA
    J Int AIDS Soc 14:41. 2011
    ..Prior to this programme, CMV retinitis was not routinely examined for, or treated, in Myanmar...
  3. pmc Spontaneous reactivation of herpes simplex virus type 1 in latently infected murine sensory ganglia
    Todd P Margolis
    Francis I Proctor Foundation, UCSF, Medical Sciences Building S 310, 513 Parnassus Ave, San Francisco, CA 94143 0412, USA
    J Virol 81:11069-74. 2007
    ..Since most cases of human viral shedding and reactivation are not associated with a known trigger, spontaneous ganglionic reactivation of HSV-1 may be a better model of human disease than existing models...
  4. ncbi request reprint Fusarium--A new culprit in the contact lens case
    Todd P Margolis
    JAMA 296:985-7. 2006
  5. pmc Herpes simplex virus type 2 (HSV-2) establishes latent infection in a different population of ganglionic neurons than HSV-1: role of latency-associated transcripts
    Todd P Margolis
    F I Proctor Foundation, University of California, San Francisco, San Francisco, CA 94143, USA
    J Virol 81:1872-8. 2007
    ....
  6. ncbi request reprint "Steel wool keratopathy": a clinical sign of chronic inflammation
    Gerami D Seitzman
    Francis I Proctor Foundation and Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USA
    Cornea 25:742-4. 2006
    ....
  7. pmc Practice patterns and opinions in the management of recurrent or chronic herpes zoster ophthalmicus
    Aileen Sy
    Department of Ophthalmology, F I Proctor Foundation, University of California, San Francisco, San Francisco, CA, USA
    Cornea 31:786-90. 2012
    ..The objective of this study was to determine current practices and opinions among cornea specialists for treating and preventing recurrences of herpes zoster ophthalmicus (HZO)...
  8. pmc The clinical differentiation of bacterial and fungal keratitis: a photographic survey
    Cyril Dalmon
    F I Proctor Foundation and Department of Ophthalmology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
    Invest Ophthalmol Vis Sci 53:1787-91. 2012
    ..The purpose of this study was to determine whether clinical signs of infectious keratitis can be used to identify the causative organism...
  9. ncbi request reprint Correlation between clinical suspicion and polymerase chain reaction verification of infectious vitritis
    Nisha Acharya
    Proctor Foundation, Department of Ophthalmology, University of California San Francisco, 95 Kirkham Street, San Francisco, CA 94143, USA
    Am J Ophthalmol 141:584-5. 2006
    ..To compare polymerase chain reaction (PCR) results to presumptive clinical diagnosis in patients with vitritis...
  10. doi request reprint Epidemiology of ulcerative keratitis in Northern California
    Bennie H Jeng
    Department of Ophthalmology, University of California, San Francisco, USA
    Arch Ophthalmol 128:1022-8. 2010
    ..To determine the incidence and associated risk factors for ulcerative keratitis in northern California...
  11. ncbi request reprint Spectrum of eye disease caused by methicillin-resistant Staphylococcus aureus
    Julie Freidlin
    F I Proctor Foundation, University of California, San Francisco, CA 94143, USA
    Am J Ophthalmol 144:313-5. 2007
    ..To compare the clinical features and antibiotic susceptibility of ocular methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA)...
  12. ncbi request reprint Rose bengal and lissamine green inhibit detection of herpes simplex virus by PCR
    Gerami D Seitzman
    Francis I Proctor Foundation, Department of Ophthalmology, University of California, San Francisco, California, USA
    Am J Ophthalmol 141:756-8. 2006
    ..To determine whether rose bengal and lissamine green affect polymerase chain reaction (PCR) detection of herpes simplex virus (HSV)...
  13. ncbi request reprint Cytomegalovirus retinitis after intravitreous triamcinolone in an immunocompetent patient
    Michael A Saidel
    Francis I Proctor Foundation, University of California at San Francisco, 95 Kirkham Street, San Francisco, CA 94143, USA
    Am J Ophthalmol 140:1141-3. 2005
    ..To report the case of a 75-year-old man with diabetes who developed cytomegalovirus (CMV) retinitis after intravitreous injection of triamcinolone acetonide (IVTA)...
  14. pmc Different mechanisms regulate productive herpes simplex virus 1 (HSV-1) and HSV-2 infections in adult trigeminal neurons
    Andrea S Bertke
    F I Proctor Foundation and Department of Ophthalmology, University of California, San Francisco, San Francisco, California, USA
    J Virol 87:6512-6. 2013
    ..HSV-1 contains no such regulatory sequences, demonstrating different mechanisms for regulating productive HSV infection in neurons...
  15. pmc Comparison of autophotomontage software programs in eyes with CMV retinitis
    Jenny Chen
    F I Proctor Foundation, San Francisco, California, USA
    Invest Ophthalmol Vis Sci 52:9339-44. 2011
    ..This study compares the quality of the mosaic products of three autophotomontage software programs, using digital fundus photographs of eyes with cytomegalovirus (CMV) retinitis...
  16. ncbi request reprint Diagnosis of conjunctival B-cell lymphoma by polymerase chain reaction heteroduplex analysis
    Erich C Strauss
    Department of Ophthalmology, University of California San Francisco Medical Center, California, San Francisco, USA
    Am J Ophthalmol 136:207-9. 2003
    ..To report a case initially assessed as giant papillary conjunctivitis and subsequently as B-cell lymphoma by the molecular technique of polymerase chain reaction heteroduplex analysis...
  17. ncbi request reprint A new mutation (Leu569Arg) within exon 13 of the TGFBI (BIGH3) gene causes lattice corneal dystrophy type I
    John F Warren
    Francis I Proctor Foundation and the Department of Ophthalmology, University of California, San Francisco, San Francisco, California 94143, USA
    Am J Ophthalmol 136:872-8. 2003
    ..To describe an American family with lattice corneal dystrophy type I, which associates with a novel mutation, Leu569Arg, of the TGFBI (BIGH3) gene...
  18. ncbi request reprint Uveitis-associated flap edema and lamellar interface fluid collection after LASIK
    Stephen D McLeod
    Francis I Proctor Foundation and the Department of Ophthalmology, University of California San Francisco, 10 Kirkham Street, San Francisco, CA 94143, USA
    Am J Ophthalmol 139:1137-9. 2005
    ..To report two cases of corneal pathology associated with anterior uveitis after laser in situ keratomileusis (LASIK)...
  19. doi request reprint Perifosine-related rapidly progressive corneal ring infiltrate
    Jeremy D Keenan
    F I Proctor Foundation and the Department of Ophthalmology, University of California, San Francisco, San Francisco, CA 94143 0944, USA
    Cornea 29:583-5. 2010
    ..To report a case of unilateral rapidly progressing corneal ring infiltration in a patient being treated with the investigational drug perifosine for Waldenström's macroglobulinemia...
  20. ncbi request reprint Management of prominent iris vascular tufts causing recurrent spontaneous hyphema
    Erich C Strauss
    Francis I Proctor Foundation and Department of Ophthalmology, University of California San Francisco, San Francisco, California 94143 0944, USA
    Cornea 24:224-6. 2005
    ..To report the management of recurrent, spontaneous hyphema associated with florid iris vascular tufts in a patient presenting for cataract surgery...
  21. ncbi request reprint Chronic recurrent varicella-zoster virus keratitis confirmed by polymerase chain reaction testing
    M Teresa Magone
    Francis I Proctor Foundation, University of California San Francisco, San Francisco, CA 94143 0944, USA
    Am J Ophthalmol 139:1135-6. 2005
    ..To report a case of chronic recurrent varicella virus epithelial keratitis in a child...
  22. ncbi request reprint Parasites on the rise: a new epidemic of Acanthamoeba keratitis
    Nisha R Acharya
    F I Proctor Foundation and Department of Ophthalmology, University of California San Francisco, San Francisco, CA 94143, USA
    Am J Ophthalmol 144:292-3. 2007
  23. pmc A5-positive primary sensory neurons are nonpermissive for productive infection with herpes simplex virus 1 in vitro
    Andrea S Bertke
    Department of Ophthalmology, University of California, San Francisco, Medical Sciences Building, s 310, 513 Parnassus Ave, Box 0412, San Francisco, CA 94143 0412, USA
    J Virol 85:6669-77. 2011
    ....
  24. pmc Cigarette smoking as a risk factor for uveitis
    Phoebe Lin
    F I Proctor Foundation, University of California, San Francisco, California 94143 0944, USA
    Ophthalmology 117:585-90. 2010
    ..To determine the association between tobacco smoking history and uveitis...
  25. ncbi request reprint Novel mutations in the carbohydrate sulfotransferase gene (CHST6) in American patients with macular corneal dystrophy
    Anthony J Aldave
    Cornea Service, The Jules Stein Eye Institute, University of California, Los Angeles, California 90095, USA
    Am J Ophthalmol 137:465-73. 2004
    ..To further characterize the mutations within the CHST6 gene responsible for causing macular corneal dystrophy in a cohort of affected patients from the United States...
  26. doi request reprint Thygeson superficial punctate keratitis and scarring
    Robert E Fintelmann
    F I Proctor Foundation, San Francisco, CA, USA
    Cornea 31:1446-8. 2012
    ..We present 4 cases with TSPK who developed sight-altering scarring after a prolonged disease course...
  27. ncbi request reprint Trends in the etiology of infectious corneal ulcers at the F. I. Proctor Foundation
    Gita Varaprasathan
    F I Proctor Foundation, University of California, San Francisco, San Francisco, CA 94143, USA
    Cornea 23:360-4. 2004
    ..The results were compared with a previous study of corneal ulcers seen from 1948 to 1976 at the same institution...
  28. ncbi request reprint Emergence of drug-resistant cytomegalovirus retinitis in the contralateral eyes of patients with AIDS treated with ganciclovir
    Yumi Imai
    Francis I Proctor Foundation for Research in Ophthalmology and Department of Ophthalmology, University of California at San Francisco, 95 Kirkham Street, San Francisco, CA 94143 0944, USA
    J Infect Dis 189:611-5. 2004
    ..023; Fisher's exact test)...
  29. ncbi request reprint Analysis of the herpes simplex virus type 1 UL6 gene in patients with stromal keratitis
    Aaron R Ellison
    The Francis I Proctor Foundation, University of California at San Francisco, San Francisco, CA 94143 0944, USA
    Virology 310:24-8. 2003
    ..We conclude that different pathogenic patterns of human HSV keratitis occur independent of genetic variation of the HSV UL6 (299-314) epitope...
  30. ncbi request reprint Atopic disease and herpes simplex eye disease: a population-based case-control study
    Tisha Prabriputaloong
    Department Francis I Proctor Foundation, University of California San Francisco, San Francisco, California, USA
    Am J Ophthalmol 142:745-9. 2006
    ..To determine whether atopy is associated with herpes simplex virus (HSV) ocular disease...
  31. doi request reprint Peripheral ulcerative keratitis associated with vasculitis manifesting asymmetrically as fuchs superficial marginal keratitis and terrien marginal degeneration
    Jeremy D Keenan
    F I Proctor Foundation, University of California, San Francisco, CA, USA
    Cornea 30:825-7. 2011
    ..To report a case of bilateral peripheral corneal thinning with an appearance of Fuchs superficial marginal keratitis in the right eye and Terrien marginal degeneration in the left eye...
  32. ncbi request reprint Metaplastic squamous epithelial downgrowth after clear corneal cataract surgery
    Donald U Stone
    Proctor Foundation, University of California San Francisco, San Francisco, CA 94143, USA
    Am J Ophthalmol 142:695-7. 2006
    ..To report a case of metaplastic squamous epithelial downgrowth after cataract surgery...
  33. ncbi request reprint Treatment of conjunctival squamous cell carcinoma with topical cidofovir
    Mark D Sherman
    Department of Ophthalmology, Southern California Permanente Medical Group, University of California, San Francisco, USA
    Am J Ophthalmol 134:432-3. 2002
    ..To describe a case of conjunctival squamous cell carcinoma in situ that was successfully treated with adjunctive topical cidofovir...
  34. doi request reprint Slitlamp biomicroscopy and photographic image analysis of herpes simplex virus stromal keratitis
    Kirk R Wilhelmus
    Sid W Richardson Ocular Microbiology Laboratory, Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, 6565 Fannin St, Houston, TX 77030, USA
    Arch Ophthalmol 127:161-6. 2009
    ..To validate photographic bioimaging for evaluating the severity of herpes simplex virus keratitis...
  35. pmc Tissue-specific splicing of the herpes simplex virus type 1 latency-associated transcript (LAT) intron in LAT transgenic mice
    Anne M Gussow
    Department of Molecular Genetics and Microbiology, Box 100266, University of Florida College of Medicine, Gainesville, FL 32610 0266, USA
    J Virol 80:9414-23. 2006
    ..Taken together, these data indicate that the regulation of expression and processing of LAT RNA within the mouse is highly cell-type specific and occurs in the absence of other viral cis- and trans-acting factors...
  36. ncbi request reprint Novel mutations in the CHST6 gene associated with macular corneal dystrophy in southern India
    John F Warren
    Francis I Proctor Foundation and the Department of Ophthalmology, University of California San Francisco, 94143 0944, USA
    Arch Ophthalmol 121:1608-12. 2003
    ..To further characterize the role of the carbohydrate sulfotransferase (CHST6) gene in macular corneal dystrophy (MCD) through identification of causative mutations in a cohort of affected patients from southern India...
  37. ncbi request reprint Does asymptomatic shedding of herpes simplex virus on the ocular surface lead to false-positive diagnostic PCR results?
    Julie F Leigh
    Br J Ophthalmol 92:435-6. 2008
  38. ncbi request reprint Ocular complications of smallpox vaccination
    Jay S Pepose
    Pepose Vision Institute, Chesterfield, Missouri 63017, USA
    Am J Ophthalmol 136:343-52. 2003
    ..To describe the ocular complications of smallpox vaccination and to discuss potential therapeutic options...
  39. ncbi request reprint Genotypic analysis of cytomegalovirus retinitis poorly responsive to intravenous ganciclovir but responsive to the ganciclovir implant
    Irene C Kuo
    Francis I Proctor Foundation and the Department of Ophthalmology, University of California San Francisco, 94143 0944, USA
    Am J Ophthalmol 135:20-5. 2003
    ..To determine whether cytomegalovirus (CMV) retinitis that responded poorly to intravenous ganciclovir therapy but responded to the ganciclovir implant was caused by virus with resistance mutations in the viral UL97 and UL54 genes...
  40. pmc Spontaneous molecular reactivation of herpes simplex virus type 1 latency in mice
    Lawrence T Feldman
    Department of Microbiology and Immunology, University of California Medical Center, Los Angeles, CA 90024, USA
    Proc Natl Acad Sci U S A 99:978-83. 2002
    ..In the absence of detectable infectious virus in these ganglia, we propose the term "spontaneous molecular reactivation" to describe this ongoing process...