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Genomes and GenesSpecies | STEPHEN MANUCKSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Serum omega-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteersSarah M Conklin
Cardiovascular Behavioral Medicine Postdoctoral Training Program, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15260, United States
Psychiatry Res 152:1-10. 2007..These findings suggest that omega-3 fatty acid status is associated with variability in affect regulation, personality and impulse control...
Reported early family environment covaries with menarcheal age as a function of polymorphic variation in estrogen receptor-αStephen B Manuck
Behavioral Physiology Laboratory, University of Pittsburgh, 506 OEH, 4015 O Hara Street, Pittsburgh, PA 15260, USA
Dev Psychopathol 23:69-83. 2011....- Salivary testosterone and a trinucleotide (CAG) length polymorphism in the androgen receptor gene predict amygdala reactivity in menStephen B Manuck
Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, United States
Psychoneuroendocrinology 35:94-104. 2010.... - The socio-economic status of communities predicts variation in brain serotonergic responsivityStephen B Manuck
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, PA 15260, USA
Psychol Med 35:519-28. 2005..Here we examine whether serotonergic responsivity covaries similarly with the SES of communities, as indexed by US Census data in the same study sample... - Central nervous system serotonergic responsivity and aggressive disposition in menStephen B Manuck
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, PA, USA
Physiol Behav 77:705-9. 2002..This finding suggests that association of the MAO-A promoter polymorphism with this behavioral phenotype may be mediated, in part, by allele-specific variation in central serotonergic responsivity... - Socio-economic status covaries with central nervous system serotonergic responsivity as a function of allelic variation in the serotonin transporter gene-linked polymorphic regionStephen B Manuck
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, 506 EH, 4015 O Hara Street, Pittsburgh, PA 15260, USA
Psychoneuroendocrinology 29:651-68. 2004..We conclude that allelic variation at 5-HTTLPR moderates the influence of social position on CNS serotonergic responsivity... - A regulatory polymorphism of the monoamine oxidase-A gene may be associated with variability in aggression, impulsivity, and central nervous system serotonergic responsivityS B Manuck
Department of Psychology, Behavioral Physiology Laboratory, University of Pittsburgh, PA 15260, USA
Psychiatry Res 95:9-23. 2000..We conclude that the MAOA-uVNTR regulatory polymorphism may contribute, in part, to individual differences in both CNS serotonergic responsivity and personality traits germane to impulse control and antagonistic behavior... - Is cardiovascular reactivity associated with atherosclerosis among hypertensives?Peter J Gianaros
Cardiovascular Behavioral Medicine Research Program, University of Pittsburgh, Pennsylvania, USA
Hypertension 40:742-7. 2002..Among hypertensives, exaggerated behaviorally evoked cardiovascular reactivity appears to be uniquely associated with greater carotid intima-media thickness but not with carotid plaque occurrence... 
Community socioeconomic status is associated with circulating interleukin-6 and C-reactive proteinKaren L Petersen
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, Pennsylvania, USA
Psychosom Med 70:646-52. 2008..e., interleukin (IL)-6 and C-reactive protein (CRP), in a midlife community sample. Growing evidence suggests that socioeconomic attributes of both individuals and communities confer risk for cardiovascular morbidity and mortality...- Potential neural embedding of parental social standingPeter J Gianaros
Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Soc Cogn Affect Neurosci 3:91-6. 2008..Thus, these findings may provide insight into the neurodevelopmental pathways impacting socioeconomic disparities in health... - Polymorphisms in the CRP gene moderate an association between depressive symptoms and circulating levels of C-reactive proteinIndrani Halder
Behavioral Physiology Laboratory, University of Pittsburgh, Pittsburgh, PA 15213, USA
Brain Behav Immun 24:160-7. 2010..In conclusion, we found that haplotypic variation in the CRP locus moderates an association of depressive symptoms with circulating CRP, which is partially mediated by BMI... - Self-reported sleep quality is associated with the metabolic syndromeJ Richard Jennings
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
Sleep 30:219-23. 2007..To determine whether a simple, structured self-report of overall sleep quality is associated with the presence of the metabolic syndrome and its component risk factors... - High omega-6 and low omega-3 fatty acids are associated with depressive symptoms and neuroticismSarah M Conklin
Department of Psychology, Allegheny College, 520 North Main Street, Meadville, PA 16335 3902, USA
Psychosom Med 69:932-4. 2007..Previously we reported that the relative concentrations of omega-3 and omega-6 polyunsaturated fatty acids in serum covary with depressive symptomatology and neuroticism in hypercholesterolemic adults... - Exaggerated blood pressure responses during mental stress are prospectively related to enhanced carotid atherosclerosis in middle-aged Finnish menJ Richard Jennings
Department of Psychiatry, University of Pittsburgh, E1329 WPIC, 3811 O Hara St, Pittsburgh, PA 15213, USA
Circulation 110:2198-203. 2004..These are the first prospective results on this relationship... - Subjective socioeconomic status and presence of the metabolic syndrome in midlife community volunteersStephen B Manuck
Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA
Psychosom Med 72:35-45. 2010.... - Reduced low-frequency heart rate variability relates to greater intimal-medial thickness of the carotid wall in two samplesClara Gautier
Department of Psychiatry and Psychology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Coron Artery Dis 18:97-104. 2007..We investigated the relationship between heart rate variability and preclinical carotid intima-media thickening, a putative index of atherosclerosis... - Covariation of psychosocial characteristics associated with cardiovascular disease: genetic and environmental influencesDouglas A Raynor
Department of Psychology, University of Pittsburgh, 405 O'Hara Street, Pittsburgh, PA 15260, USA
Psychosom Med 64:191-203; discussion 204-5. 2002.... - Self-reported sleep duration is associated with the metabolic syndrome in midlife adultsMartica H Hall
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Sleep 31:635-43. 2008..In the present study, we evaluated the relationship between sleep duration and presence of the metabolic syndrome, which is a cluster of physiologically interrelated risk factors for cardiometabolic disease... - Serotonergic function in the central nervous system is associated with daily ratings of positive moodJanine D Flory
Department of Psychology, University of Pittsburgh, 4015 O Hara Street, Pittsburgh, PA 15260, USA
Psychiatry Res 129:11-9. 2004..e., Neuroticism). These results suggest that deficiencies in serotonergic function may reflect the relative absence of positive mood... - Preclinical atherosclerosis covaries with individual differences in reactivity and functional connectivity of the amygdalaPeter J Gianaros
Department of Psychiatry and Psychology, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, Pennsylvania 15213, USA
Biol Psychiatry 65:943-50. 2009.... - A comparison of d, l-fenfluramine and citalopram challenges in healthy adultsJanine D Flory
Behavioral Physiology Laboratory 506 OEH, University of Pittsburgh, 4015 O Hara Street, Pittsburgh, PA 15260, USA
Psychopharmacology (Berl) 174:376-80. 2004..49, P's< or =0.02). The magnitude of the correlations is notable given the length of time between challenges. The results support the use of citalopram as an alternate neuroendocrine challenge to index CNS serotonergic responsivity... - Parental education is related to C-reactive protein among female middle-aged community volunteersJennifer E Phillips
Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
Brain Behav Immun 23:677-83. 2009..This association may help explain the increased risk of atherosclerotic cardiovascular morbidity and mortality conferred by low childhood socioeconomic status... - Healthy adolescents' neural response to reward: associations with puberty, positive affect, and depressive symptomsErika E Forbes
University of Pittsburgh, USA
J Am Acad Child Adolesc Psychiatry 49:162-72.e1-5. 2010..The current study focused on puberty-specific changes in brain function and their association with mood... - Stimulated production of proinflammatory cytokines covaries inversely with heart rate variabilityAnna L Marsland
Behavioral Immunology Laboratory, Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
Psychosom Med 69:709-16. 2007..As yet, no direct human evidence links parasympathetic activity to inflammatory competence... - Sequence variation in the primate dopamine transporter gene and its relationship to social dominanceCassandra M Miller-Butterworth
Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, USA
Mol Biol Evol 25:18-28. 2008..This suggests that the DAT gene has followed different evolutionary trajectories during primate speciation... - Lower central serotonergic responsivity is associated with preclinical carotid artery atherosclerosisMatthew F Muldoon
Center for Clinical Pharmacology, University of Pittsburgh, Pittsburgh, PA 15260, USA
Stroke 38:2228-33. 2007..This investigation tested a hypothesized association between central serotonergic functioning and preclinical atherosclerosis... - The serotonin transporter: sequence variation in Macaca fascicularis and its relationship to dominanceCassandra M Miller-Butterworth
Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, A300 Crabtree Hall, 130 De Soto Street, Pittsburgh, PA, USA
Behav Genet 37:678-96. 2007..No individual variants or haplotypes were significantly associated with social rank or 5-HIAA concentrations; however, certain serotonin transporter diplotypes may modulate acquisition of dominance status... - Positive affective style covaries with stimulated IL-6 and IL-10 production in a middle-aged community sampleAric A Prather
Behavioral Immunology Laboratory, Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
Brain Behav Immun 21:1033-7. 2007..Further exploration of this potential psychophysiological pathway is warranted... - Effects of six anti-hypertensive medications on cognitive performanceMatthew F Muldoon
Division of Clinical Pharmacology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA
J Hypertens 20:1643-52. 2002..To describe and compare the effects of six different antihypertensive medications on cognitive performance... - Individual differences in stressor-evoked blood pressure reactivity vary with activation, volume, and functional connectivity of the amygdalaPeter J Gianaros
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Neurosci 28:990-9. 2008.... - Antagonistic characteristics are positively associated with inflammatory markers independently of trait negative emotionalityAnna L Marsland
Behavioral Immunology Laboratory, Department of Psychology, University of Pittsburgh, 3943 O Hara Street, Pittsburgh, PA 15260, USA
Brain Behav Immun 22:753-61. 2008.... - Interleukin-6 covaries inversely with hippocampal grey matter volume in middle-aged adultsAnna L Marsland
Behavioral Immunology Laboratory, University of Pittsburgh, PA 15260, USA
Biol Psychiatry 64:484-90. 2008..In the current study, we extend this work to test whether systemic inflammation is associated with reduced grey matter volume of the hippocampus... - Serum phospholipid docosahexaenonic acid is associated with cognitive functioning during middle adulthoodMatthew F Muldoon
Center for Clinical Pharmacology, University of Pittsburgh, Pittsburgh, PA 15260, USA
J Nutr 140:848-53. 2010..These findings suggest that DHA is related to brain health throughout the lifespan and may have implications for clinical trials of neuropsychiatric disorders... - Greater intima-media thickness in the carotid bulb is associated with reduced baroreflex sensitivityPeter J Gianaros
Cardiovascular Behavioral Medicine Research Program, University of Pittsburgh, Pennsylvania, USA
Am J Hypertens 15:486-91. 2002..These results suggest that subclinical atherosclerosis, specifically in a region with high baroreceptor density, is associated with a reduced sensitivity of the baroreflex... - A urinary marker of oxidative stress covaries positively with hostility among midlife community volunteersJudith E Carroll
MS, Behavioral Immunology Laboratory, University of Pittsburgh, Old Engineering Hall, Suite 600, 3943 O Hara St, Pittsburgh, PA 15260
Psychosom Med 72:273-80. 2010..One possibility is that hostility is associated with oxidative stress. Here, we explore relationships between hostility and a measure of systemic oxidative stress among a mid-life sample... - Divergent effects of genetic variation in endocannabinoid signaling on human threat- and reward-related brain functionAhmad R Hariri
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Biol Psychiatry 66:9-16. 2009..Fatty acid amide hydrolase (FAAH) is a key enzyme in regulating endocannabinoid (eCB) signaling. A common single nucleotide polymorphism (C385A) in the human FAAH gene has been associated with increased risk for addiction and obesity... - Citalopram intervention for hostility: results of a randomized clinical trialThomas W Kamarck
Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
J Consult Clin Psychol 77:174-88. 2009..04). The findings have implications for understanding the central nervous system correlates of hostility, its associations with other psychosocial risk factors for CVD, and, potentially, the design of effective interventions... - Approach to a social stranger is associated with low central nervous system serotonergic responsivity in female cynomolgus monkeys (Macaca fascicularis)Stephen B Manuck
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA
Am J Primatol 61:187-94. 2003..We conclude that in female cynomolgus monkeys, social impulsivity (vs. inhibition) correlates inversely with individual differences in CNS serotonergic activity, as assessed by neuroendocrine challenge... - Normative variation in self-reported sleep quality and sleep debt is associated with stimulated pro-inflammatory cytokine productionAric A Prather
Department of Psychology, University of Pittsburgh, PA 15260, United States
Biol Psychol 82:12-7. 2009..Further exploration of this potential psychophysiological pathway linking sleep difficulty and inflammatory disease susceptibility is warranted... - Systemic inflammation and the metabolic syndrome among middle-aged community volunteersAnna L Marsland
Behavioral Immunology Laboratory, Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
Metabolism 59:1801-8. 2010..The inclusion of inflammatory markers in the clinical definition of metabolic syndrome seems warranted and may improve prognostic assessment of risk of type 2 diabetes mellitus and cardiovascular disease... - Trait positive affect and antibody response to hepatitis B vaccinationAnna L Marsland
Behavioral Immunology Laboratory, Department of Psychology, University of Pittsburgh, USA
Brain Behav Immun 20:261-9. 2006..These data provide initial evidence that individual differences in dispositional positive affect may be of health significance, being related to an in vivo immune response relevant for protection against infection... - Low central nervous system serotonergic responsivity is associated with the metabolic syndrome and physical inactivityMatthew F Muldoon
Divisions of Clinical Pharmacology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA
J Clin Endocrinol Metab 89:266-71. 2004..These findings reveal a heretofore unrecognized association between reduced central serotonergic responsivity and the metabolic syndrome... - Community socioeconomic status is associated with carotid artery atherosclerosis in untreated, hypertensive menKaren L Petersen
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh School of Medicine, 4015 O Hara Street, Pittsburgh, PA 15218, USA
Am J Hypertens 19:560-6. 2006..In this study we examined whether community SES is similarly associated with preclinical vascular disease, as measured by carotid artery ultrasonography... - Stress, immune reactivity and susceptibility to infectious diseaseAnna L Marsland
Department of Psychology, University of Pittsburgh, 210 S Bouquet Street, 15260, Pittsburgh, PA, USA
Physiol Behav 77:711-6. 2002.... - The metabolic syndrome is associated with reduced central serotonergic responsivity in healthy community volunteersMatthew F Muldoon
Division of Clinical Pharmacology, Departments of Medicine and Epidemiology, University of Pittsburgh, 4015 O Hara Street, Pittsburgh, PA 15260, USA
J Clin Endocrinol Metab 91:718-21. 2006..The pathobiology of the metabolic syndrome remains unclear. The central nervous system is likely to be involved via regulation of eating, physical activity, blood pressure, and metabolism... - Apolipoprotein E polymorphism and preclinical carotid artery disease in untreated hypertensive menMaria E Bleil
Behavioral Physiology Laboratory, Department of Psychology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
Eur J Cardiovasc Prev Rehabil 13:98-100. 2006..The apolipoprotein E (apoE) polymorphism was evaluated alone, and in interaction with smoking status, in predicting carotid intima-medial thickness and plaque among 182 untreated, hypertensive, white men (mean age 56+/-8.9 years)... - Stimulated production of interleukin-8 covaries with psychosocial risk factors for inflammatory disease among middle-aged community volunteersAnna L Marsland
Behavioral Immunology Laboratory, Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA
Brain Behav Immun 21:218-28. 2007..Further exploration of this potential psychophysiological pathway is warranted... - Anger-related personality traits and carotid artery atherosclerosis in untreated hypertensive menMaria E Bleil
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, 4015 O Hara St, Pittsburgh, PA 15260, USA
Psychosom Med 66:633-9. 2004..To determine whether anger-related personality traits are associated with carotid artery atherosclerosis in untreated hypertensive patients... - Interleukin-6 covaries inversely with cognitive performance among middle-aged community volunteersAnna L Marsland
Behavioral Immunology Laboratory, Department of Psychology, 3943 O Hara Street, Pittsburgh, PA 15260, USA
Psychosom Med 68:895-903. 2006..The current investigation extends the study of relationships between plasma IL-6 and cognitive performance to healthy middle-aged adults and to an examination of more specific cognitive domains... - Randomized trial of the effects of simvastatin on cognitive functioning in hypercholesterolemic adultsMatthew F Muldoon
Center for Clinical Pharmacology, University of Pittsburgh, Pennsylvania 15260, USA
Am J Med 117:823-9. 2004..The current study was designed to confirm and extend those findings... - Retest reliability of prolactin response to dl-fenfluramine challenge in adultsJanine D Flory
Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
Neuropsychopharmacology 26:269-72. 2002..57 for PRL "area under the curve," p <.0001). These findings are consistent with speculation that variability in indices of central serotonergic function reflects a temporally stable dimension of individual differences... - Perceived social support moderates the link between threat-related amygdala reactivity and trait anxietyLuke W Hyde
Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
Neuropsychologia 49:651-6. 2011..Moreover, our results indicate that links between neural reactivity and behavior are not static but rather may be contingent on social resources... - Effects of hemoconcentration and sympathetic activation on serum lipid responses to brief mental stressElizabeth A Bachen
Department of Psychology, Mills College, Oakland, CA 94613, USA
Psychosom Med 64:587-94. 2002..This study evaluated these two hypotheses by manipulation of sympathetically mediated responses to stress using a nonselective adrenoceptor antagonist, labetalol... - Neuroendocrine response to intravenous citalopram in healthy control subjects: pharmacokinetic influencesFrancis E Lotrich
Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
Psychopharmacology (Berl) 178:268-75. 2005..The neuroendocrine response to intravenous citalopram may provide an acute, functional, in vivo measure of the neural serotonin (5-HT) system... - Individual differences in typical reappraisal use predict amygdala and prefrontal responsesEmily M Drabant
Department of Psychology, Stanford University, Stanford, California 94305, USA
Biol Psychiatry 65:367-73. 2009..Such spontaneous emotion regulation might play an important role in normal and pathological responses to the emotional challenges of everyday life... - White-coat hypertension and autonomic nervous system dysregulationSerina A Neumann
Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
Am J Hypertens 18:584-8. 2005..The current study asks whether individuals with white-coat hypertension have abnormal autonomic-cardiac regulation, similar to that observed in sustained or persistent hypertension... - A convergent-divergent approach to context processing, general intellectual functioning, and the genetic liability to schizophreniaAngus W MacDonald
Department of Psychology, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455, USA
Neuropsychology 19:814-21. 2005.... - COMT val158Met and executive control: a test of the benefit of specific deficits to translational researchAngus W MacDonald
Department of Psychology, University of Pittsburgh, USA
J Abnorm Psychol 116:306-12. 2007..These data suggest that the interpretability gained by including task manipulations to uncover specific deficits can enhance associations between cognitive and genetic levels of analysis... - Impulsiveness and cigarette smokingJanine D Flory
Department of Psychology, Queens College, 65 30 Kissena Blvd, Flushing, NY 11367, USA
Psychosom Med 71:431-7. 2009..g., any tobacco use versus dependence) or considered more than one variety of impulsiveness simultaneously... - Neural basis of individual differences in impulsivity: contributions of corticolimbic circuits for behavioral arousal and controlSarah M Brown
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
Emotion 6:239-45. 2006..Together, these findings suggest that dispositional impulsivity is influenced by the functional interplay of corticolimbic behavioral arousal and control circuits... - Delay discounting and smoking: association with the Fagerström Test for Nicotine Dependence but not cigarettes smoked per dayMaggie M Sweitzer
Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
Nicotine Tob Res 10:1571-5. 2008..These results suggest that DD among smokers is not simply the result of nicotine exposure, but may be an important marker for dependence, especially urgency to smoke in the morning... - Neurobiological pathways linking socioeconomic position and healthPeter J Gianaros
Department of Psychiatry, Thomas Detre Hall, University of Pittsburgh, Pittsburgh, PA 15213, USA
Psychosom Med 72:450-61. 2010.... - Heart rate variability is associated with polymorphic variation in the choline transporter geneSerina A Neumann
Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
Psychosom Med 67:168-71. 2005.... - Long-chain omega-3 fatty acid intake is associated positively with corticolimbic gray matter volume in healthy adultsSarah M Conklin
Department of Psychiatry, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15260, United States
Neurosci Lett 421:209-12. 2007..Here, we test whether omega-3 fatty acid intake in humans varies with individual differences in gray matter volume, an in vivo, systems-level index of neuronal integrity... - Preference for immediate over delayed rewards is associated with magnitude of ventral striatal activityAhmad R Hariri
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Neurosci 26:13213-7. 2006..They also highlight a specific neurocognitive mechanism that may contribute to increased risk for addiction... - Variability within alpha- and beta-adrenoreceptor genes as a predictor of cardiovascular function at rest and in response to mental challengeJeanne M McCaffery
Centers for Behavioral and Preventive Medicine, Brown Medical School and The Miriam Hospital, Providence, Rhode Island 02903, USA
J Hypertens 20:1105-14. 2002.... - Human choline transporter gene variation is associated with corticolimbic reactivity and autonomic-cholinergic functionSerina A Neumann
Department of Psychiatry and Behavioral Sciences, Eastern Virginia Medical School, 825 Fairfax Avenue, Norfolk, VA 23501
Biol Psychiatry 60:1155-62. 2006..Here, functional magnetic resonance imaging (fMRI) was used to examine the relation between a single nucleotide polymorphism (SNP) in CHT1 on regional brain reactivity relevant to autonomic (cholinergic) function... - Dispositional impulsivity in normal and abnormal samplesJanine D Flory
Department of Psychiatry, Box 1230, One Gustave Levy Place, Mount Sinai School of Medicine, New York, NY 10029, United States
J Psychiatr Res 40:438-47. 2006..Results from these analyses also lend support to a large body of work that demonstrates that normal and abnormal personality features are related... - Effects of exercise on cardiovascular outcomes in monkeys with risk factors for coronary heart diseaseJ Koudy Williams
Comparative Medicine Clinical Research Center, Wake Forest University Health Sciences, Medical Center Blvd, Winston Salem, NC 27157, USA
Arterioscler Thromb Vasc Biol 23:864-71. 2003..However, the mechanisms mediating the beneficial effects of exercise remain ambiguous. In particular, it is uncertain whether exercise inhibits the development of atherosclerosis, a major pathobiologic process underlying heart disease... - Trait negative affect: toward an integrated model of understanding psychological risk for impairment in cardiac autonomic functionMaria E Bleil
Department of Psychiatry, University of California San Francisco, 3333 California Street, Suite 465, San Francisco, CA 94143 0848, USA
Psychosom Med 70:328-37. 2008..g., autonomic nervous system [ANS] dysfunction), the degree to which a general tendency to experience negative emotions may account for these relations is not known... - Genetics of monoamine metabolites in baboons: overlapping sets of genes influence levels of 5-hydroxyindolacetic acid, 3-hydroxy-4-methoxyphenylglycol, and homovanillic acidJeffrey Rogers
Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227, USA
Biol Psychiatry 55:739-44. 2004..Genetic analyses of monoamine levels in primates can provide novel information concerning the genetics of variation among humans... - Allelic variation in the serotonin transporter gene-linked polymorphic region (5-HTTLPR) and cardiovascular reactivity in young adult male and female twins of European-American descentJeanne M McCaffery
Centers for Behavioral and Preventive Medicine, Brown Medical School and The Miriam Hospital, Providence, RI 02903, USA
Psychosom Med 65:721-8. 2003..To examine the effect of length variation in the serotonin transporter gene-linked polymorphic region (5-HTTLPR) on individual differences in cardiovascular response to psychological challenge... - Ovarian dysfunction, stress, and disease: a primate continuumJay R Kaplan
Department of Pathology, Wake Forest University, School of Medicine, Winston-Salem, NC, USA
ILAR J 45:89-115. 2004..g., sedentary lifestyle, high-fat diet) permissive to the development of chronic disease... - The association between racial identity and hypertension in African-American adults: elevated resting and ambulatory blood pressure as outcomesHayley S Thompson
Ruttenberg Cancer Center, Mount Sinai School of Medicine, New York, NY 10029, USA
Ethn Dis 12:20-8. 2002.... - Central nervous system monoamine correlates of social dominance in cynomolgus monkeys (Macaca fascicularis)Jay R Kaplan
Pathology Comparative Medicine, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157 1040, USA
Neuropsychopharmacology 26:431-43. 2002..05). The Dominance-HVA association observed here is consistent with recent speculation that social extraversion, a dominance-related personality trait in humans, may also reflect heightened central nervous system dopaminergic activity... - Genetic variation in human NPY expression affects stress response and emotionZhifeng Zhou
Laboratory of Neurogenetics, NIAAA, NIH, Bethesda, Maryland 20892, USA
Nature 452:997-1001. 2008..These convergent findings are consistent with the function of NPY as an anxiolytic peptide and help to explain inter-individual variation in resiliency to stress, a risk factor for many diseases... - Temporal stability of individual differences in amygdala reactivityStephen B Manuck
Am J Psychiatry 164:1613-4. 2007
Research Grants
- BIOBEHAVIORAL STUDIES OF CARDIOVASCULAR DISEASESTEPHEN MANUCK; Fiscal Year: 2007..abstract_text> ..
- NEUROGENETICS, SEROTONIN, AND HUMAN AGGRESSIONSTEPHEN MANUCK; Fiscal Year: 2003..This application is the resubmission of a prior proposal of the same title. ..