Jeffrey J Mans

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi The degree of microbiome complexity influences the epithelial response to infection
    Jeffrey J Mans
    Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA
    BMC Genomics 10:380. 2009
  2. ncbi Role of Porphyromonas gingivalis SerB in gingival epithelial cell cytoskeletal remodeling and cytokine production
    Yoshiaki Hasegawa
    Department of Oral Biology and Center for Molecular Microbiology, College of Dentistry, University of Florida, Gainesville, FL 32610 0424, USA
    Infect Immun 76:2420-7. 2008
  3. ncbi Gingival epithelial cell transcriptional responses to commensal and opportunistic oral microbial species
    Yoshiaki Hasegawa
    Department of Oral Biology and Center for Molecular Microbiology, College of Dentistry, University of Florida, Gainesville, FL 32610 0424, USA
    Infect Immun 75:2540-7. 2007
  4. ncbi Distinct transcriptional profiles characterize oral epithelium-microbiota interactions
    Martin Handfield
    Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL 32610 0424, USA
    Cell Microbiol 7:811-23. 2005
  5. ncbi Role of the ATM-checkpoint kinase 2 pathway in CDT-mediated apoptosis of gingival epithelial cells
    Mounia Alaoui-El-Azher
    Department of Oral Biology and Center for Molecular Microbiology, College of Dentistry, University of Florida, Gainesville, Florida, United States of America
    PLoS ONE 5:e11714. 2010
  6. ncbi Microarray analysis of human epithelial cell responses to bacterial interaction
    Jeffrey J Mans
    Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL 32610-0424, USA
    Infect Disord Drug Targets 6:299-309. 2006

Collaborators

Detail Information

Publications6

  1. ncbi The degree of microbiome complexity influences the epithelial response to infection
    Jeffrey J Mans
    Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida, USA
    BMC Genomics 10:380. 2009
    ..Using oral epithelial cells as a model, we hypothesized that the virulence of pathogenic species may vary depending on the complexity of the flora that interacts with host cells...
  2. ncbi Role of Porphyromonas gingivalis SerB in gingival epithelial cell cytoskeletal remodeling and cytokine production
    Yoshiaki Hasegawa
    Department of Oral Biology and Center for Molecular Microbiology, College of Dentistry, University of Florida, Gainesville, FL 32610 0424, USA
    Infect Immun 76:2420-7. 2008
    ..SerB is thus capable of modulating host cell signal transduction that impacts the actin cytoskeleton and cytokine production...
  3. ncbi Gingival epithelial cell transcriptional responses to commensal and opportunistic oral microbial species
    Yoshiaki Hasegawa
    Department of Oral Biology and Center for Molecular Microbiology, College of Dentistry, University of Florida, Gainesville, FL 32610 0424, USA
    Infect Immun 75:2540-7. 2007
    ..Stimulation of secretion of proinflammatory cytokines from epithelial cells may reflect the invasive phenotype of F. nucleatum and contribute to the greater pathogenic potential of F. nucleatum than of S. gordonii...
  4. ncbi Distinct transcriptional profiles characterize oral epithelium-microbiota interactions
    Martin Handfield
    Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL 32610 0424, USA
    Cell Microbiol 7:811-23. 2005
    ..These studies help unravel the complex and dynamic interactions between host epithelial cells and endogenous bacteria that can cause opportunistic infections...
  5. ncbi Role of the ATM-checkpoint kinase 2 pathway in CDT-mediated apoptosis of gingival epithelial cells
    Mounia Alaoui-El-Azher
    Department of Oral Biology and Center for Molecular Microbiology, College of Dentistry, University of Florida, Gainesville, Florida, United States of America
    PLoS ONE 5:e11714. 2010
    ..This model potentially explains conflicting reports on the biological activity of the A. actinomycetemcomitans CDT...
  6. ncbi Microarray analysis of human epithelial cell responses to bacterial interaction
    Jeffrey J Mans
    Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL 32610-0424, USA
    Infect Disord Drug Targets 6:299-309. 2006
    ..In particular, we will expand upon the lessons that have been learned from gastro-intestinal and oral pathogens, as well as from members of the commensal flora...