Research Topics
| T M ManiniSummaryAffiliation: University of Florida Country: USA Publications
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Detail Information
Publications
Growth hormone responses to acute resistance exercise with vascular restriction in young and old menTodd M Manini
University of Florida, Department of Aging and Geriatric Research, Gainesville, USA
Growth Horm IGF Res 22:167-72. 2012..We hypothesized that low-load RE with vascular restriction would attenuate the known age-related reduction in GH response to RE...
Development of physical disability in older adultsTodd Manini
Department of Aging and Geriatric Research University of Florida, Gainesville, FL 32611 0107, USA
Curr Aging Sci 4:184-91. 2011..This article will give a general overview of the models and risk factors that explain the development of physical disability...
Physical function and self-rated health status as predictors of mortality: results from longitudinal analysis in the ilSIRENTE studyMatteo Cesari
Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Universita Cattolica del Sacro Cuore, Roma, Italy
BMC Geriatr 8:34. 2008..Aim of the present study is to compare the predictive value for mortality of measures of physical function and SRH status, and test their possible interactions...- Knee extension strength cutpoints for maintaining mobilityTodd M Manini
Institute on Aging, Department of Aging and Geriatric Research, Amsterdam, The Netherlands
J Am Geriatr Soc 55:451-7. 2007..To identify levels of knee extensor strength that are associated with high and low risk of incident severe mobility limitation (SML) in initially well-functioning older adults... - Efficacy of resistance and task-specific exercise in older adults who modify tasks of everyday lifeTodd Manini
Department of Aging and Geriatrics, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32605, USA
J Gerontol A Biol Sci Med Sci 62:616-23. 2007.... - Activity energy expenditure and mobility limitation in older adults: differential associations by sexTodd M Manini
Department of Aging and Geriatric Research, University of Florida, Gainesville, Florida, USA
Am J Epidemiol 169:1507-16. 2009..34, 95% confidence interval: 0.98, 1.85). Greater energy expenditure from any and all physical activity was significantly associated with reduced risk of developing mobility limitation among men, but not among women... - Energy expenditure and agingTodd M Manini
University of Florida, Institute on Aging, Department of Aging and Geriatric Research, 210 E Mowry Rd, PO Box 112610, Gainesville, FL 32611 2610, United States
Ageing Res Rev 9:1-11. 2010..Recent evidence suggests that activity EE has an important role in dictating lifespan and thus places emphasis on future research to uncover the underlying biological mechanisms. The study of EE continues to unlock clues to aging... - Activity energy expenditure and change in body composition in late lifeTodd M Manini
University of Florida, Department of Aging and Geriatric Research, Gainesville, FL 32611 0107, USA
Am J Clin Nutr 90:1336-42. 2009..Change in body composition, specifically loss of fat-free mass and gain in fat mass, in older adults is a major pathway leading to the onset of functional decline and physical disability... - Effects of exercise on mobility in obese and nonobese older adultsTodd M Manini
Department of Aging and Geriatric Research, College of Medicine, University of Florida, Gainesville, Florida, USA
Obesity (Silver Spring) 18:1168-75. 2010..5%; SA: +2.5%) and nonobese older adults (PA: +18.6%; SA: +6.1%). A moderate intensity PA intervention improves physical function in older adults, but the positive benefits are attenuated with obesity... - Myogenic and proteolytic mRNA expression following blood flow restricted exerciseT M Manini
Department of Aging and Geriatric Research, University of Florida, Gainesville, FL 32611 0107, USA
Acta Physiol (Oxf) 201:255-63. 2011..In summary, myogenic genes are unchanged and proteolytic genes associated with muscle remodelling are reduced 8 h following low-load BFR exercise... - Dynapenia and aging: an updateTodd M Manini
Institute on Aging and Department of Aging and Geriatric Research, University of Florida, Gainesville, FL 32611, USA
J Gerontol A Biol Sci Med Sci 67:28-40. 2012..However, these efforts are expected to provide a specific understanding of the role that dynapenia plays in the loss of physical function and increased risk for disability among older adults... - European ancestry and resting metabolic rate in older African AmericansT M Manini
Department of Aging and Geriatric Research, University of Florida, Institute on Aging, Gainesville, USA
Eur J Clin Nutr 65:663-7. 2011..We sought to evaluate the association between RMR and EA in African Americans... - Reduced physical activity increases intermuscular adipose tissue in healthy young adultsTodd M Manini
Department of Aging and Geriatrics, Institute on Aging, University of Florida, Gainesville, FL 32611 0107, USA
Am J Clin Nutr 85:377-84. 2007..Although several studies have described adaptations in muscle after reduced physical activity, the change in IMAT in healthy young adults is unknown... - Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophyThomas W Buford
Institute on Aging, University of Florida, Gainesville, FL 32611, United States
Ageing Res Rev 9:369-83. 2010..Elucidating biochemical pathways related to accelerated muscle atrophy may allow for improved discovery of therapeutic treatments related to sarcopenia... - Blood flow restricted exercise and skeletal muscle healthTodd M Manini
Department of Aging and Geriatric Research, Institute on Aging, University of Florida, Gainesville, FL, USA
Exerc Sport Sci Rev 37:78-85. 2009..However, emerging research on low-intensity exercise with blood flow restriction challenges this paradigm. This article will describe the BFR exercise model and discuss its efficacy, potential mechanisms, and clinical viability... - Resistance and functional training reduces knee extensor position fluctuations in functionally limited older adultsTodd M Manini
Musculoskeletal Research Laboratory, Syracuse University, Syracuse, NY, USA
Eur J Appl Physiol 95:436-46. 2005.... - Electromyographic activity of the lumbar and hip extensors during dynamic trunk extension exerciseBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, 820 Comstock Avenue, Room 201, Syracuse, NY 13244, USA
Arch Phys Med Rehabil 83:1547-52. 2002..To evaluate the effects of exercise intensity and multiple sets on muscle activation patterns during trunk extension exercise... - Leg muscle activity during walking with assistive devices at varying levels of weight bearingBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, NY 13244, USA
Arch Phys Med Rehabil 85:1555-60. 2004..To evaluate the muscle activation patterns at varying levels of weight-bearing forces during assisted walking with an axillary crutch and a recently designed device that allows weight transfer through the pelvic girdle (ED Walker)... - Knee extensor isometric unsteadiness does not predict functional limitation in older adultsTodd M Manini
Department of Exercise Science, Syracuse University, Syracuse, NY, USA
Am J Phys Med Rehabil 84:112-21. 2005..Because the strength-to-weight ratio predicted the most variance in functional performance, it is recommended that muscle strength be improved to increase function in older adults... - Sex differences in muscle fatigability and activation patterns of the human quadriceps femorisBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, NY 13244, USA
Eur J Appl Physiol 94:196-206. 2005.... - Derecruitment of the lumbar musculature with fatiguing trunk extension exerciseBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, Syracuse, New York 13244, USA
Spine (Phila Pa 1976) 28:282-7. 2003..This was a descriptive study involving 20 healthy individuals... - Gender differences in skeletal muscle fatigability are related to contraction type and EMG spectral compressionBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, Syracuse 13244, USA
J Appl Physiol 94:2263-72. 2003..45 vs. 0.19). These findings suggest that gender differences in muscle fatigue are influenced by muscle contraction type and frequency shifts in the EMG signal but not by alterations in the synergistic activation patterns... - Midlife physical activity and mobility in older age: The InCHIANTI studyKushang V Patel
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA
Am J Prev Med 31:217-24. 2006.... - Misconceptions about strength exercise among older adultsTodd M Manini
Musculoskeletal Research Laboratory, Syracuse University, NY 13244, USA
J Aging Phys Act 13:422-33. 2005..046). More education is needed about the benefits and recommendations to ensure proper use of current strength-exercise protocols among older adults... - Adaptations in human neuromuscular function following prolonged unweighting: II. Neurological properties and motor imagery efficacyBrian C Clark
Musculoskeletal Research Laboratory, Department of Exercise Science, Syracuse University, New York, USA
J Appl Physiol 101:264-72. 2006.... - Sarcopenia =/= dynapeniaBrian C Clark
Department of Biomedical Sciences, Ohio University, 211 Irvine Hall, Athens, OH 45701, USA
J Gerontol A Biol Sci Med Sci 63:829-34. 2008..Rather, we propose that alternative mechanisms underlie dynapenia (i.e., alterations in contractile properties or neurologic function), and urge that greater attention be paid to these variables in determining their role in dynapenia... - Daily activity energy expenditure and mortality among older adultsTodd M Manini
National Institute on Aging, Laboratory of Epidemiology, Demography and Biometry, Bethesda, MD 20892, USA
JAMA 296:171-9. 2006..Exercise is associated with mortality benefits but simply expending energy through any activity in an individual's free-living environment may confer survival advantages... - Evaluating task modification as an objective measure of functional limitation: repeatability and comparabilityTodd M Manini
Department of Exercise Science, Syracuse University, New York, USA
J Gerontol A Biol Sci Med Sci 61:718-25. 2006..The purpose of this study was to develop a task modification scale to examine its reliability and comparability to timed performance and common measures of physical function and impairment... - Effect of prolonged unweighting of human skeletal muscle on neuromotor force controlBrian C Clark
Interdisciplinary Institute for Neuromusculoskeletal Research, Department of Biomedical Sciences, Ohio University College of Osteopathic Medicine, 211 Irvine Hall, Athens, OH 45701, USA
Eur J Appl Physiol 100:53-62. 2007.... - Electromyographic activity of the trunk extensor muscles: effect of varying hip position and lumbar posture during Roman chair exerciseJohn M Mayer
US Spine and Sport Foundation San Diego, 0532 Via Mallorca, d, La Jolla, CA 92037, USA
Arch Phys Med Rehabil 83:1543-6. 2002..To evaluate the effect of hip position and lumbar posture on the surface electromyographic activity of the trunk extensors during Roman chair exercise...