Research Topics
Species | S J MandelSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Publications
Diagnostic use of ultrasonography in patients with nodular thyroid diseaseSusan J Mandel
Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Endocr Pract 10:246-52. 2004..Moreover, real-time ultrasonography facilitates characterization of features associated with an increased risk of a malignant lesion. High-resolution thyroid ultrasonography is a dynamic tool for endocrinologists...
Sonographic imaging of thyroid nodules and cervical lymph nodesStephanie A Fish
Department of Medicine, University of Pennsylvania School of Medicine, 1 Maloney, Endocrinology, HUP, 3400 Spruce Street, Philadelphia, PA 19104, USA
Endocrinol Metab Clin North Am 37:401-17, ix. 2008..This article discusses the sonographic features of thyroid nodules associated with malignancy and the role of ultrasound in the management of patients with thyroid cancer...
Atypical hypothyroidism and the very low birthweight infantS J Mandel
Division of Endocrinology, Diabetes and Metabolism, University of Pennsylvania, Philadelphia, USA
Thyroid 10:693-5. 2000..In view of these results, it is suggested that T4 measurements be obtained routinely in all LBW and VLBW infants, with additional routine repeat blood specimens...
Radioactive iodine and the salivary glandsSusan J Mandel
Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania Medical School, Philadelphia, Pennsylvania 19104, USA
Thyroid 13:265-71. 2003..Treatment of the varied complications that may develop encompass numerous approaches and include gland massage, sialogogic agents, duct probing, antibiotics, mouthwashes, good oral hygiene, and adequate hydration...
Hypothyroidism and chronic autoimmune thyroiditis in the pregnant state: maternal aspectsSusan J Mandel
University of Pennsylvania School of Medicine, 1 Maloney, Endocrinology, HUP, 3400 Spruce Street, Philadelphia, PA 19104, USA
Best Pract Res Clin Endocrinol Metab 18:213-24. 2004..The diverse etiologies of maternal hypothyroidism may require different increments in thyroxine dose during pregnancy, and generally the postpartum dosage requirement returns to pre-pregnancy levels...
A 64-year-old woman with a thyroid noduleSusan J Mandel
Division of Endocrinology, Diabetes, and Metabolism, Hospital of the University of Pennsylvania, Philadelphia, USA
JAMA 292:2632-42. 2004
The role of MR imaging in detecting nodal disease in thyroidectomy patients with rising thyroglobulin levelsS L Kaplan
University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
AJNR Am J Neuroradiol 30:608-12. 2009..In this study, we examine the role of MR imaging in this subgroup of patients...
Sonographic appearance of focal thyroiditisJ E Langer
Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce St, Philadelphia, PA 19104, USA
AJR Am J Roentgenol 176:751-4. 2001..Biopsy of these lesions is still necessary because there are no sonographic features that can reliably diagnose these lesions as thyroiditis and differentiate them from other lesions...
Superiority of iodine-123 compared with iodine-131 scanning for thyroid remnants in patients with differentiated thyroid cancerS J Mandel
Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
Clin Nucl Med 26:6-9. 2001..I-123 imaging may prove to be the preferred procedure in such settings in patients with differentiated thyroid cancer...
Sonographic imaging of cervical lymph nodes in patients with thyroid cancerJill E Langer
Department of Radiology, University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
Neuroimaging Clin N Am 18:479-89, vii-viii. 2008..In patients who have had thyroidectomy for cancer, sonographic evaluation has proved to be the most sensitive imaging technique to detect thyroid cancer recurrence in the neck...
c-Met expression in tall cell variant papillary carcinoma of the thyroidHeather C Nardone
Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
Cancer 98:1386-93. 2003..This current study examined c-Met expression in tall cell variant tumors compared with other types of papillary thyroid carcinoma and benign thyroid disease...
Comparison of efficacy of 2220 MBq versus 3700 MBq I-131 for ablation of thyroid remnant in patients with differentiated thyroid cancerS A Fish
Division of Endocrinology, Diabetes and Metabolism University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Q J Nucl Med Mol Imaging 54:560-3. 2010..We evaluated the efficacy of two doses of I-131 (2220 MBq versus 3700 MBq) after thyroid hormone withdrawal for thyroid remnant ablation postoperatively in patients with differentiated thyroid cancer (DTC)...
The diagnostic dilemma of follicular variant of papillary thyroid carcinomaSusan B Kesmodel
Department of Surgery, Division of Endocrinology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
Surgery 134:1005-12; discussion 1012. 2003..CONCLUSION: Although the sensitivity of FNA in establishing a diagnosis of FVPTC is low, FNA identifies patients with suspicious lesions in whom IP is important in guiding operative management...
False-positive xerostomia following radioactive iodine treatment: case reportSusan J Mandel
Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania Medical School, Philadelphia, PA, USA
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:e43-7. 2007..Emphasis is placed on the diagnostic techniques used in the differential diagnosis...
I-123 imaging after recombinant human thyroid-stimulating hormone to diagnose metastatic disease in an intubated patient with papillary thyroid cancerStephanie A Fish
Department of Endocrinology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Clin Nucl Med 27:895. 2002
Comparison of 123I scintigraphy at 5 and 24 hours in patients with differentiated thyroid cancerLalitha K Shankar
Division of Nuclear Medicine, Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
J Nucl Med 43:72-6. 2002..CONCLUSION: The diagnostic yield of planar diagnostic 123I scintigraphy at 24 h was superior to that at 5 h for lesion detection and image quality, and images obtained after 131I therapy did not reveal unknown metastatic foci...
Comparison of I-123 and I-131 for whole-body imaging after stimulation by recombinant human thyrotropin: a preliminary reportGregory S Anderson
Division of Nuclear Medicine, Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Clin Nucl Med 28:93-6. 2003..CONCLUSION: The results of this preliminary investigation are promising regarding the utility of rhTSH-stimulated I-123 WBS as an alternate approach to rhTSH-stimulated I-131 WBS in patients at low risk for recurrence...
Interinstitutional review of thyroid fine-needle aspirations: impact on clinical management of thyroid nodulesZ W Baloch
Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
Diagn Cytopathol 25:231-4. 2001..In conclusion, we strongly recommend interinstitution cytology consultation on referred thyroid FNA cases, since our data showed a significant change in diagnosis, thus affecting patient management...
Iodine-123 as a diagnostic imaging agent in differentiated thyroid carcinoma: a comparison with iodine-131 post-treatment scanning and serum thyroglobulin measurementMuammer Urhan
Division of Nuclear Medicine, Department of Radiology, Department of Medicine University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
Eur J Nucl Med Mol Imaging 34:1012-7. 2007..In this study we assessed the role of 123I in comparison with 131I post-treatment imaging in patients with thyroid cancer...
Safety of completion thyroidectomy following unilateral lobectomy for well-differentiated thyroid cancerMichael E Kupferman
Department of Otolaryngology-Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, U.S.A
Laryngoscope 112:1209-12. 2002....
Are detection and treatment of thyroid insufficiency in pregnancy feasible?Susan J Mandel
Division of Endocrinology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
Thyroid 15:44-53. 2005..Women with autoimmune thyroid disease prior to pregnancy are at increased risk for thyroid insufficiency during pregnancy and postpartum thyroiditis and should be monitored with TSH during pregnancy...
Safety of modified radical neck dissection for differentiated thyroid carcinomaMichael E Kupferman
Department of Otolaryngology-Head and Neck Surgery, University of Pennsylvania School of Medicine Philadelphia, Pennsylvania 19104, USA
Laryngoscope 114:403-6. 2004..Two patients developed chyle leaks. CONCLUSIONS: When ND is necessary for the treatment of thyroid malignancies, the procedure can be performed safely with acceptable morbidity...
Patterns of lateral neck metastasis in papillary thyroid carcinomaMichael E Kupferman
Department of Otolaryngology-Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia, USA
Arch Otolaryngol Head Neck Surg 130:857-60. 2004..We believe that a comprehensive ND, including removal of transverse cervical and spinal accessory nodes, is necessary for the complete clearance of lateral metastases...
Hyperfunctioning intrathyroidal parathyroid cystMichael R Rickels
Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
J Clin Endocrinol Metab 89:1051-2. 2004
Chronic granulomatous lesions after thyroidectomy: imaging findingsJill E Langer
Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce St, Philadelphia, PA 19104, USA
AJR Am J Roentgenol 185:1350-4. 2005..These lesions may appear as complex cystic masses on CT and MRI and may have increased activity on PET. Percutaneous biopsy can establish the diagnosis of an inflammatory lesion and can exclude underlying active infection and malignancy...
Phase II trial of sorafenib in advanced thyroid cancerVandana Gupta-Abramson
Developmental TherapeuticsProgram of the Abramson CancerCenter, University of Pennsylvania, Philadelphia, PA 19104, USA
J Clin Oncol 26:4714-9. 2008....
A 21-year-old woman with consumptive hypothyroidism due to a vascular tumor expressing type 3 iodothyronine deiodinaseStephen A Huang
Division of Endocrinology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Clin Endocrinol Metab 87:4457-61. 2002..This first example of consumptive hypothyroidism in an adult indicates that the inactivation rate of thyroid hormone by D3 in a vascular tumor can stress the secretory capacity even of the TSH-stimulated normal adult thyroid gland...
Therapy insight: management of Graves' disease during pregnancyGrace W Chan
Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Nat Clin Pract Endocrinol Metab 3:470-8. 2007..Neonatal thyrotoxicosis can occur in the first few days of life after clearance of maternal antithyroid drug, and can last for several months, until maternal antibodies are also cleared...
Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society Clinical Practice GuidelineMarcos Abalovich
Endocrinology Division, Durand Hospital, Buenos Aires, Argentina
J Clin Endocrinol Metab 92:S1-47. 2007..The objective is to provide clinical guidelines for the management of thyroid problems present during pregnancy and in the postpartum...
Indications for thyroid FNA and pre-FNA requirements: a synopsis of the National Cancer Institute Thyroid Fine-Needle Aspiration State of the Science ConferenceEdmund S Cibas
Department of Pathology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Diagn Cytopathol 36:390-9. 2008..http://thyroidfna.cancer.gov/pages/info/agenda/)..
Cervical chordoma masquerading as a thyroid neoplasm: a case reportAnjali Saqi
Department of Pathology, New York Presbyterian Hospital, Columbia Presbyterian Medial Center, New York, 10032, USA
Diagn Cytopathol 32:296-8. 2005....
Management guidelines for patients with thyroid nodules and differentiated thyroid cancerDavid S Cooper
Sinai Hospital of Baltimore and Johns Hopkins University School of Medicine, MD, USA
Thyroid 16:109-42. 2006
Thyroid disorders during pregnancyShane O LeBeau
Division of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Endocrinol Metab Clin North Am 35:117-36, vii. 2006
Management of thyroid nodules detected at US: Society of Radiologists in Ultrasound consensus conference statementMary C Frates
Radiology 237:794-800. 2005..The recommendations in this consensus statement, which are based on analysis of the current literature and common practice strategies, are thought to represent a reasonable approach to thyroid nodular disease...
Hypocalciuric hypercalcemia and autoantibodies against the calcium-sensing receptorMichael R Rickels
N Engl J Med 351:2237-8; author reply 2237-8. 2004
