Elizabeth A Manci

Summary

Affiliation: University of South Alabama
Country: USA

Publications

  1. ncbi request reprint Causes of death in sickle cell disease: an autopsy study
    Elizabeth A Manci
    Centralized Pathology Unit for Sickle Cell Disease, Department of Pathology, University of South Alabama, Mobile, USA
    Br J Haematol 123:359-65. 2003
  2. ncbi request reprint Perivascular fibrosis in the bone marrow in sickle cell disease
    Elizabeth A Manci
    Department of Pathology, University of South Alabama, Mobile 36604, USA
    Arch Pathol Lab Med 128:634-9. 2004
  3. ncbi request reprint Cardiofaciocutaneous syndrome (CFC) with congenital peripheral neuropathy and nonorganic malnutrition: an autopsy study
    Elizabeth A Manci
    Pediatric Pathology, University of South Alabama Children s and Women s Hospital, Mobile, 36604, USA
    Am J Med Genet A 137:1-8. 2005
  4. pmc Pathology of Berkeley sickle cell mice: similarities and differences with human sickle cell disease
    Elizabeth A Manci
    Department of Pathology, Centralized Pathology Unit for Sickle Cell Disease, University of South Alabama, Mobile, AL 36604, USA
    Blood 107:1651-8. 2006
  5. ncbi request reprint Chimerism and cure: hematologic and pathologic correction of murine sickle cell disease
    Leslie S Kean
    Division of Hem Onc BMT, Department of Pediatrics, Emory University School of Medicine, 2040 Ridgewood Dr NE, Atlanta, GA 30322, USA
    Blood 102:4582-93. 2003
  6. pmc Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability
    Lewis L Hsu
    Marian Anderson Sickle Cell Center at St Christopher s Hospital for Children, Drexel University College of Medicine, Philadelphia, PA 19134, USA
    Blood 109:3088-98. 2007
  7. pmc Morphological and functional platelet abnormalities in Berkeley sickle cell mice
    Arun S Shet
    The Laboratory of Blood and Vascular Biology, Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    Blood Cells Mol Dis 41:109-18. 2008

Collaborators

  • Marcelo G Horenstein
  • Johnson Haynes
  • Lewis L Hsu
  • M T Gladwin
  • Arun S Shet
  • Leslie S Kean
  • Marketa Jirouskova
  • Narla Mohandas
  • Christin A Janczak
  • Adewole Adamson
  • Barry S Coller
  • Jacqueline R M Stevens
  • Thomas J Hoffmann
  • Therese Cynober
  • Jennifer Perry
  • Can Balkan
  • David R Archer
  • Andrew B Adams
  • Christian P Larsen
  • David Holtzclaw
  • Shana Coley

Detail Information

Publications7

  1. ncbi request reprint Causes of death in sickle cell disease: an autopsy study
    Elizabeth A Manci
    Centralized Pathology Unit for Sickle Cell Disease, Department of Pathology, University of South Alabama, Mobile, USA
    Br J Haematol 123:359-65. 2003
    ..3%). This study shows that the first 24 h after presentation for medical care is an especially perilous time for patients with sickle cell disease and an acute event. Close monitoring and prompt aggressive treatment are warranted...
  2. ncbi request reprint Perivascular fibrosis in the bone marrow in sickle cell disease
    Elizabeth A Manci
    Department of Pathology, University of South Alabama, Mobile 36604, USA
    Arch Pathol Lab Med 128:634-9. 2004
    ..The pattern of these signals is reminiscent of the underlying vascular architecture, but histopathology of this tissue has not been adequately studied...
  3. ncbi request reprint Cardiofaciocutaneous syndrome (CFC) with congenital peripheral neuropathy and nonorganic malnutrition: an autopsy study
    Elizabeth A Manci
    Pediatric Pathology, University of South Alabama Children s and Women s Hospital, Mobile, 36604, USA
    Am J Med Genet A 137:1-8. 2005
    ..Additional studies of other cases of CFC are needed...
  4. pmc Pathology of Berkeley sickle cell mice: similarities and differences with human sickle cell disease
    Elizabeth A Manci
    Department of Pathology, Centralized Pathology Unit for Sickle Cell Disease, University of South Alabama, Mobile, AL 36604, USA
    Blood 107:1651-8. 2006
    ..While our study reinforces the fundamental strength of this model, the notable differences warrant careful consideration when drawing parallels to human sickle cell disease...
  5. ncbi request reprint Chimerism and cure: hematologic and pathologic correction of murine sickle cell disease
    Leslie S Kean
    Division of Hem Onc BMT, Department of Pediatrics, Emory University School of Medicine, 2040 Ridgewood Dr NE, Atlanta, GA 30322, USA
    Blood 102:4582-93. 2003
    ..As the critical hematopoietic organs were not corrected without full RBC replacement, 100% peripheral blood RBC chimerism becomes the most important benchmark for cure after nonmyeloablative BMT...
  6. pmc Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability
    Lewis L Hsu
    Marian Anderson Sickle Cell Center at St Christopher s Hospital for Children, Drexel University College of Medicine, Philadelphia, PA 19134, USA
    Blood 109:3088-98. 2007
    ..Although the time course is shorter than typical pulmonary hypertension in human sickle cell disease, these results demonstrate that hemolytic anemia is sufficient to produce endothelial dysfunction and global dysregulation of NO...
  7. pmc Morphological and functional platelet abnormalities in Berkeley sickle cell mice
    Arun S Shet
    The Laboratory of Blood and Vascular Biology, Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
    Blood Cells Mol Dis 41:109-18. 2008
    ..Thus, additional studies are needed to assess whether large platelets contribute either to pulmonary hypertension or the large vessel arterial occlusion that produces stroke in some children with sickle cell disease...