Jacek Mamczarz

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi Galantamine counteracts development of learning impairment in guinea pigs exposed to the organophosphorus poison soman: clinical significance
    Jacek Mamczarz
    Division of Translational Toxicology, Department Epidemiology and Public Health, University of Maryland School of Medicine, 10 S Pine St Suite 900, Baltimore, MD 21210, USA
    Neurotoxicology 32:785-98. 2011
  2. ncbi An acute exposure to a sub-lethal dose of soman triggers anxiety-related behavior in guinea pigs: interactions with acute restraint
    Jacek Mamczarz
    Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Neurotoxicology 31:77-84. 2010
  3. ncbi Preclinical investigation of the topical administration of phenserine: transdermal flux, cholinesterase inhibition, and cognitive efficacy
    Tadanobu Utsuki
    Drug Design and Development Section, Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
    J Pharmacol Exp Ther 321:353-61. 2007

Collaborators

  • Edson X Albuquerque
  • Nigel H Greig
  • Tadanobu Utsuki
  • Nao Uchimura
  • Harold W Holloway
  • Mitsuru Irikura
  • Donald K Ingram
  • Hiroshi Moriuchi
  • Qian sheng Yu
  • Edward L Spangler
  • Qian-sheng Yu
  • Tetsumi Irie

Detail Information

Publications3

  1. ncbi Galantamine counteracts development of learning impairment in guinea pigs exposed to the organophosphorus poison soman: clinical significance
    Jacek Mamczarz
    Division of Translational Toxicology, Department Epidemiology and Public Health, University of Maryland School of Medicine, 10 S Pine St Suite 900, Baltimore, MD 21210, USA
    Neurotoxicology 32:785-98. 2011
    ..In conclusion, learning impairment develops months after a single exposure to 1xLD50 soman, and galantamine prevents both the acute toxicity and the delayed cognitive deficits triggered by this OP poison...
  2. ncbi An acute exposure to a sub-lethal dose of soman triggers anxiety-related behavior in guinea pigs: interactions with acute restraint
    Jacek Mamczarz
    Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Neurotoxicology 31:77-84. 2010
    ..It is concluded that a single exposure to sub-lethal doses of soman triggers long-lasting anxiogenesis and decreased locomotor activity and that acute restraint stress modifies the magnitude of these effects...
  3. ncbi Preclinical investigation of the topical administration of phenserine: transdermal flux, cholinesterase inhibition, and cognitive efficacy
    Tadanobu Utsuki
    Drug Design and Development Section, Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
    J Pharmacol Exp Ther 321:353-61. 2007
    ..Particular benefits over oral therapies might include avoiding first-pass metabolic effects and improved dosing compliance...