C J Malanga

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi Augmentation of cocaine-sensitized dopamine release in the nucleus accumbens of adult mice following prenatal cocaine exposure
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
    Dev Neurosci 31:76-89. 2009
  2. ncbi Prenatal exposure to cocaine increases the rewarding potency of cocaine and selective dopaminergic agonists in adult mice
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Biol Psychiatry 63:214-21. 2008
  3. ncbi Prenatal exposure to cocaine alters the development of conditioned place-preference to cocaine in adult mice
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Boston, MA 02129, United States
    Pharmacol Biochem Behav 87:462-71. 2007
  4. ncbi Intracranial self-stimulation in FAST and SLOW mice: effects of alcohol and cocaine
    Eric W Fish
    Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Psychopharmacology (Berl) 220:719-30. 2012
  5. ncbi Mephedrone (4-methylmethcathinone) and intracranial self-stimulation in C57BL/6J mice: comparison to cocaine
    J Elliott Robinson
    Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7025, USA
    Behav Brain Res 234:76-81. 2012
  6. ncbi The rewarding and locomotor-sensitizing effects of repeated cocaine administration are distinct and separable in mice
    Thorfinn T Riday
    Laboratory of Developmental Neuropharmacology, Department of Neurology, University of North Carolina at Chapel Hill, NC 27599 7025, USA
    Neuropharmacology 62:1858-66. 2012
  7. ncbi Orexin-1 receptor antagonism does not reduce the rewarding potency of cocaine in Swiss-Webster mice
    Thorfinn T Riday
    Laboratory of Developmental Neuropharmacology, Department of Neurology, University of North Carolina at Chapel Hill, USA
    Brain Res 1431:53-61. 2012
  8. ncbi Alcohol, cocaine, and brain stimulation-reward in C57Bl6/J and DBA2/J mice
    Eric W Fish
    Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Alcohol Clin Exp Res 34:81-9. 2010
  9. ncbi Neuropathological consequences of prenatal cocaine exposure in the mouse
    Jia-Qian Ren
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Room 2508, 149 13th Street, Charlestown, MA 02129, USA
    Int J Dev Neurosci 22:309-20. 2004
  10. ncbi Does drug abuse beget drug abuse? Behavioral analysis of addiction liability in animal models of prenatal drug exposure
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital East, CNY 149, Room 2508 149 13th Street, Charlestown, MA 02129, USA
    Brain Res Dev Brain Res 147:47-57. 2003

Research Grants

  1. Effects of Acute and Chronic Alcohol on Brain Reward in Mice
    C J Malanga; Fiscal Year: 2010
  2. Effect of prenatal cocaine exposure on brain reward
    C Malanga; Fiscal Year: 2007

Collaborators

Detail Information

Publications11

  1. ncbi Augmentation of cocaine-sensitized dopamine release in the nucleus accumbens of adult mice following prenatal cocaine exposure
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
    Dev Neurosci 31:76-89. 2009
    ..This effect was not due to fetal malnutrition or changes in the total tissue DA content. Early developmental cocaine exposure may alter adaptation of brain reward systems to chronic psychostimulant exposure in adulthood...
  2. ncbi Prenatal exposure to cocaine increases the rewarding potency of cocaine and selective dopaminergic agonists in adult mice
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Biol Psychiatry 63:214-21. 2008
    ..Animal models of prenatal cocaine exposure have yielded differing results depending on the behavioral method used to assess drug potency...
  3. ncbi Prenatal exposure to cocaine alters the development of conditioned place-preference to cocaine in adult mice
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Boston, MA 02129, United States
    Pharmacol Biochem Behav 87:462-71. 2007
    ..Sensitivity to acute stress is also altered by prenatal cocaine exposure, consistent with earlier findings in this model...
  4. ncbi Intracranial self-stimulation in FAST and SLOW mice: effects of alcohol and cocaine
    Eric W Fish
    Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Psychopharmacology (Berl) 220:719-30. 2012
    ..Sensitivity to the stimulant and rewarding effects of alcohol may be genetically correlated traits that predispose individuals to develop an alcohol use disorder...
  5. ncbi Mephedrone (4-methylmethcathinone) and intracranial self-stimulation in C57BL/6J mice: comparison to cocaine
    J Elliott Robinson
    Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7025, USA
    Behav Brain Res 234:76-81. 2012
    ..Given the public health concern of stimulant abuse, future studies will be necessary to determine the cellular and behavioral effects of acute and chronic mephedrone use...
  6. ncbi The rewarding and locomotor-sensitizing effects of repeated cocaine administration are distinct and separable in mice
    Thorfinn T Riday
    Laboratory of Developmental Neuropharmacology, Department of Neurology, University of North Carolina at Chapel Hill, NC 27599 7025, USA
    Neuropharmacology 62:1858-66. 2012
    ....
  7. ncbi Orexin-1 receptor antagonism does not reduce the rewarding potency of cocaine in Swiss-Webster mice
    Thorfinn T Riday
    Laboratory of Developmental Neuropharmacology, Department of Neurology, University of North Carolina at Chapel Hill, USA
    Brain Res 1431:53-61. 2012
    ..The data are discussed in the context of prior findings of SB 334867 effects on drug-seeking and drug-consuming behaviors...
  8. ncbi Alcohol, cocaine, and brain stimulation-reward in C57Bl6/J and DBA2/J mice
    Eric W Fish
    Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Alcohol Clin Exp Res 34:81-9. 2010
    ..These experiments had 2 objectives: first, to establish the effects of alcohol on ICSS responding in the C57Bl6/J (C57) and DBA2/J (DBA) mouse strains; and second, to compare these effects to those of the psychostimulant cocaine...
  9. ncbi Neuropathological consequences of prenatal cocaine exposure in the mouse
    Jia-Qian Ren
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Room 2508, 149 13th Street, Charlestown, MA 02129, USA
    Int J Dev Neurosci 22:309-20. 2004
    ....
  10. ncbi Does drug abuse beget drug abuse? Behavioral analysis of addiction liability in animal models of prenatal drug exposure
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital East, CNY 149, Room 2508 149 13th Street, Charlestown, MA 02129, USA
    Brain Res Dev Brain Res 147:47-57. 2003
    ....
  11. ncbi Cocaine and SKF-82958 potentiate brain stimulation reward in Swiss-Webster mice
    Brian Gilliss
    Department of Psychiatry, Harvard Medical School and McLean Hospital, MRC 217, 115 Mill Street, Belmont, MA 02478, USA
    Psychopharmacology (Berl) 163:238-48. 2002
    ..The reward-facilitating effects of low doses of cocaine and SKF-82958 are additive (or synergistic). These data suggest that SKF-82958 may decrease cocaine-seeking behavior by mechanisms related to reward rather than aversion...

Research Grants2

  1. Effects of Acute and Chronic Alcohol on Brain Reward in Mice
    C J Malanga; Fiscal Year: 2010
    ....
  2. Effect of prenatal cocaine exposure on brain reward
    C Malanga; Fiscal Year: 2007
    ..abstract_text> ..