C J Malanga

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Prenatal exposure to cocaine increases the rewarding potency of cocaine and selective dopaminergic agonists in adult mice
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Biol Psychiatry 63:214-21. 2008
  2. pmc Prenatal exposure to cocaine alters the development of conditioned place-preference to cocaine in adult mice
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Boston, MA 02129, United States
    Pharmacol Biochem Behav 87:462-71. 2007
  3. doi request reprint Augmentation of cocaine-sensitized dopamine release in the nucleus accumbens of adult mice following prenatal cocaine exposure
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
    Dev Neurosci 31:76-89. 2009
  4. pmc Levetiracetam has opposite effects on alcohol- and cocaine-related behaviors in C57BL/6J mice
    J Elliott Robinson
    Laboratory of Developmental Neuropharmacology, Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7025, USA
    Neuropsychopharmacology 38:1322-33. 2013
  5. pmc Mephedrone (4-methylmethcathinone) and intracranial self-stimulation in C57BL/6J mice: comparison to cocaine
    J Elliott Robinson
    Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7025, USA
    Behav Brain Res 234:76-81. 2012
  6. pmc Intracranial self-stimulation in FAST and SLOW mice: effects of alcohol and cocaine
    Eric W Fish
    Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Psychopharmacology (Berl) 220:719-30. 2012
  7. pmc The rewarding and locomotor-sensitizing effects of repeated cocaine administration are distinct and separable in mice
    Thorfinn T Riday
    Laboratory of Developmental Neuropharmacology, Department of Neurology, University of North Carolina at Chapel Hill, NC 27599 7025, USA
    Neuropharmacology 62:1858-66. 2012
  8. pmc Orexin-1 receptor antagonism does not reduce the rewarding potency of cocaine in Swiss-Webster mice
    Thorfinn T Riday
    Laboratory of Developmental Neuropharmacology, Department of Neurology, University of North Carolina at Chapel Hill, USA
    Brain Res 1431:53-61. 2012
  9. doi request reprint Alcohol, cocaine, and brain stimulation-reward in C57Bl6/J and DBA2/J mice
    Eric W Fish
    Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Alcohol Clin Exp Res 34:81-9. 2010
  10. pmc Neuropathological consequences of prenatal cocaine exposure in the mouse
    Jia Qian Ren
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Room 2508, 149 13th Street, Charlestown, MA 02129, USA
    Int J Dev Neurosci 22:309-20. 2004

Collaborators

Detail Information

Publications12

  1. pmc Prenatal exposure to cocaine increases the rewarding potency of cocaine and selective dopaminergic agonists in adult mice
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA
    Biol Psychiatry 63:214-21. 2008
    ..Animal models of prenatal cocaine exposure have yielded differing results depending on the behavioral method used to assess drug potency...
  2. pmc Prenatal exposure to cocaine alters the development of conditioned place-preference to cocaine in adult mice
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Boston, MA 02129, United States
    Pharmacol Biochem Behav 87:462-71. 2007
    ..Sensitivity to acute stress is also altered by prenatal cocaine exposure, consistent with earlier findings in this model...
  3. doi request reprint Augmentation of cocaine-sensitized dopamine release in the nucleus accumbens of adult mice following prenatal cocaine exposure
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
    Dev Neurosci 31:76-89. 2009
    ..This effect was not due to fetal malnutrition or changes in the total tissue DA content. Early developmental cocaine exposure may alter adaptation of brain reward systems to chronic psychostimulant exposure in adulthood...
  4. pmc Levetiracetam has opposite effects on alcohol- and cocaine-related behaviors in C57BL/6J mice
    J Elliott Robinson
    Laboratory of Developmental Neuropharmacology, Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7025, USA
    Neuropsychopharmacology 38:1322-33. 2013
    ..The opposite effects of LEV pretreatment on alcohol- and cocaine-related behaviors may predict its clinical utility in the treatment of patients with alcohol, but not psychostimulant abuse disorders...
  5. pmc Mephedrone (4-methylmethcathinone) and intracranial self-stimulation in C57BL/6J mice: comparison to cocaine
    J Elliott Robinson
    Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7025, USA
    Behav Brain Res 234:76-81. 2012
    ..Given the public health concern of stimulant abuse, future studies will be necessary to determine the cellular and behavioral effects of acute and chronic mephedrone use...
  6. pmc Intracranial self-stimulation in FAST and SLOW mice: effects of alcohol and cocaine
    Eric W Fish
    Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Psychopharmacology (Berl) 220:719-30. 2012
    ..Sensitivity to the stimulant and rewarding effects of alcohol may be genetically correlated traits that predispose individuals to develop an alcohol use disorder...
  7. pmc The rewarding and locomotor-sensitizing effects of repeated cocaine administration are distinct and separable in mice
    Thorfinn T Riday
    Laboratory of Developmental Neuropharmacology, Department of Neurology, University of North Carolina at Chapel Hill, NC 27599 7025, USA
    Neuropharmacology 62:1858-66. 2012
    ....
  8. pmc Orexin-1 receptor antagonism does not reduce the rewarding potency of cocaine in Swiss-Webster mice
    Thorfinn T Riday
    Laboratory of Developmental Neuropharmacology, Department of Neurology, University of North Carolina at Chapel Hill, USA
    Brain Res 1431:53-61. 2012
    ..The data are discussed in the context of prior findings of SB 334867 effects on drug-seeking and drug-consuming behaviors...
  9. doi request reprint Alcohol, cocaine, and brain stimulation-reward in C57Bl6/J and DBA2/J mice
    Eric W Fish
    Department of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Alcohol Clin Exp Res 34:81-9. 2010
    ..These experiments had 2 objectives: first, to establish the effects of alcohol on ICSS responding in the C57Bl6/J (C57) and DBA2/J (DBA) mouse strains; and second, to compare these effects to those of the psychostimulant cocaine...
  10. pmc Neuropathological consequences of prenatal cocaine exposure in the mouse
    Jia Qian Ren
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital, Room 2508, 149 13th Street, Charlestown, MA 02129, USA
    Int J Dev Neurosci 22:309-20. 2004
    ....
  11. ncbi request reprint Does drug abuse beget drug abuse? Behavioral analysis of addiction liability in animal models of prenatal drug exposure
    C J Malanga
    Laboratory of Molecular and Developmental Neuroscience, Department of Neurology, Massachusetts General Hospital East, CNY 149, Room 2508 149 13th Street, Charlestown, MA 02129, USA
    Brain Res Dev Brain Res 147:47-57. 2003
    ....
  12. ncbi request reprint Cocaine and SKF-82958 potentiate brain stimulation reward in Swiss-Webster mice
    Brian Gilliss
    Department of Psychiatry, Harvard Medical School and McLean Hospital, MRC 217, 115 Mill Street, Belmont, MA 02478, USA
    Psychopharmacology (Berl) 163:238-48. 2002
    ..It is not known if SKF-82958 reduces drug-seeking behaviors in animals exposed previously to cocaine by causing reward-like effects or withdrawal-like aversive effects...

Research Grants2

  1. Effects of Acute and Chronic Alcohol on Brain Reward in Mice
    C J Malanga; Fiscal Year: 2010
    ....
  2. Effect of prenatal cocaine exposure on brain reward
    C Malanga; Fiscal Year: 2007
    ..abstract_text> ..