Dennis G Maki

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. doi request reprint A novel antimicrobial and antithrombotic lock solution for hemodialysis catheters: a multi-center, controlled, randomized trial
    Dennis G Maki
    Department of Medicine, Section of Infectious Diseases, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Crit Care Med 39:613-20. 2011
  2. doi request reprint In vitro studies of a novel antimicrobial luer-activated needleless connector for prevention of catheter-related bloodstream infection
    Dennis G Maki
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin School of Medicine and Public Health and the University of Wisconsin Hospital and Clinics, Madison, WI 53792, USA
    Clin Infect Dis 50:1580-7. 2010
  3. ncbi request reprint Prevalence, consequences, and solutions
    Dennis G Maki
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
    Pharmacotherapy 27:121S-125S. 2007
  4. ncbi request reprint Infected bilomas in liver transplant recipients: clinical features, optimal management, and risk factors for mortality
    Nasia Safdar
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin, Madison, WI, USA
    Clin Infect Dis 39:517-25. 2004
  5. doi request reprint Cohort study of the pathogenesis and molecular epidemiology of catheter-related bloodstream infection in neonates with peripherally inserted central venous catheters
    Jeffery S Garland
    Department of Pediatrics, Wheaton Franciscan Healthcare St Joseph, Milwaukee, Wisconsin, USA
    Infect Control Hosp Epidemiol 29:243-9. 2008
  6. ncbi request reprint The pathogenesis of catheter-related bloodstream infection with noncuffed short-term central venous catheters
    Nasia Safdar
    Section of Infectious Diseases, Department of Medicine, Medical School, University of Wisconsin, Madison, WI 53792, USA
    Intensive Care Med 30:62-7. 2004
  7. ncbi request reprint Effectiveness of preemptive barrier precautions in controlling nosocomial colonization and infection by methicillin-resistant Staphylococcus aureus in a burn unit
    Nasia Safdar
    Infectious Diseases, Department of Medicine, University of Wisconsin Medical School and University of Wisconsin Hospital and Clinics, Madison, Wisconsin 53792, USA
    Am J Infect Control 34:476-83. 2006
  8. ncbi request reprint A vancomycin-heparin lock solution for prevention of nosocomial bloodstream infection in critically ill neonates with peripherally inserted central venous catheters: a prospective, randomized trial
    Jeffery S Garland
    Department of Pediatrics, St Joseph s Hospital, Milwaukee, Wisconsin, USA
    Pediatrics 116:e198-205. 2005
  9. ncbi request reprint The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies
    Dennis G Maki
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, USA
    Mayo Clin Proc 81:1159-71. 2006
  10. ncbi request reprint Infected bilomas in liver transplant recipients, incidence, risk factors and implications for prevention
    Adnan Said
    Section of Gastroenterology and Hepatology, Department of Medicine, University of Wisconsin Hospital and Clinics, Madison, WI, USA
    Am J Transplant 4:574-82. 2004

Detail Information

Publications51

  1. doi request reprint A novel antimicrobial and antithrombotic lock solution for hemodialysis catheters: a multi-center, controlled, randomized trial
    Dennis G Maki
    Department of Medicine, Section of Infectious Diseases, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Crit Care Med 39:613-20. 2011
    ..Catheter-related bloodstream infection is the greatest threat to the safety of patients on hemodialysis. Catheter lock solutions containing heparin have been linked to an increased risk of hemorrhage and thrombocytopenia...
  2. doi request reprint In vitro studies of a novel antimicrobial luer-activated needleless connector for prevention of catheter-related bloodstream infection
    Dennis G Maki
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin School of Medicine and Public Health and the University of Wisconsin Hospital and Clinics, Madison, WI 53792, USA
    Clin Infect Dis 50:1580-7. 2010
    ....
  3. ncbi request reprint Prevalence, consequences, and solutions
    Dennis G Maki
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
    Pharmacotherapy 27:121S-125S. 2007
    ..Education of the patient and the prescriber, as well as antimicrobial stewardship programs, are necessary to avert a global antibiotic resistance catastrophe...
  4. ncbi request reprint Infected bilomas in liver transplant recipients: clinical features, optimal management, and risk factors for mortality
    Nasia Safdar
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin, Madison, WI, USA
    Clin Infect Dis 39:517-25. 2004
    ..Infected hepatic fluid collections (bilomas) are a major infectious complication of liver transplantation. Limited data exist on management and outcome of biloma...
  5. doi request reprint Cohort study of the pathogenesis and molecular epidemiology of catheter-related bloodstream infection in neonates with peripherally inserted central venous catheters
    Jeffery S Garland
    Department of Pediatrics, Wheaton Franciscan Healthcare St Joseph, Milwaukee, Wisconsin, USA
    Infect Control Hosp Epidemiol 29:243-9. 2008
    ..To better define the pathogenesis of catheter-related bloodstream infection (BSI) in neonates with peripherally inserted central venous catheters (PICCs) to guide the development of more effective strategies for prevention...
  6. ncbi request reprint The pathogenesis of catheter-related bloodstream infection with noncuffed short-term central venous catheters
    Nasia Safdar
    Section of Infectious Diseases, Department of Medicine, Medical School, University of Wisconsin, Madison, WI 53792, USA
    Intensive Care Med 30:62-7. 2004
    ..We report a prospective study undertaken to determine the pathogenesis of CVC-related BSI...
  7. ncbi request reprint Effectiveness of preemptive barrier precautions in controlling nosocomial colonization and infection by methicillin-resistant Staphylococcus aureus in a burn unit
    Nasia Safdar
    Infectious Diseases, Department of Medicine, University of Wisconsin Medical School and University of Wisconsin Hospital and Clinics, Madison, Wisconsin 53792, USA
    Am J Infect Control 34:476-83. 2006
    ....
  8. ncbi request reprint A vancomycin-heparin lock solution for prevention of nosocomial bloodstream infection in critically ill neonates with peripherally inserted central venous catheters: a prospective, randomized trial
    Jeffery S Garland
    Department of Pediatrics, St Joseph s Hospital, Milwaukee, Wisconsin, USA
    Pediatrics 116:e198-205. 2005
    ..Most CRBSIs with long-term devices derive from intraluminal contaminants. The objective of this study was to ascertain the safety and the efficacy of a vancomycin-heparin lock solution for prevention of CRBSI...
  9. ncbi request reprint The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies
    Dennis G Maki
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, USA
    Mayo Clin Proc 81:1159-71. 2006
    ....
  10. ncbi request reprint Infected bilomas in liver transplant recipients, incidence, risk factors and implications for prevention
    Adnan Said
    Section of Gastroenterology and Hepatology, Department of Medicine, University of Wisconsin Hospital and Clinics, Madison, WI, USA
    Am J Transplant 4:574-82. 2004
    ..T-tube drainage post-transplantation bears reassessment. The protective effect of ursodeoxycholic acid found in this study warrants confirmation in a prospective multicenter, randomized trial...
  11. doi request reprint Microbiologic assessment of disposable sterile endoscopic sheaths to replace high-level disinfection in reprocessing: a prospective clinical trial with nasopharygoscopes
    Carla J Alvarado
    Center for Quality and Productivity Improvement, Systems Engineering Initiative for Patient Safety, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Am J Infect Control 37:408-13. 2009
    ....
  12. ncbi request reprint Are antimicrobial-impregnated catheters effective? Don't throw out the baby with the bathwater
    Christopher J Crnich
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, Madison, WI 53792, USA
    Clin Infect Dis 38:1287-92. 2004
    ....
  13. ncbi request reprint Case study and panel discussion
    Dennis G Maki
    Section of Infectious Diseases, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA
    Pharmacotherapy 27:136S-143S. 2007
  14. ncbi request reprint Meta-analysis: methods for diagnosing intravascular device-related bloodstream infection
    Nasia Safdar
    University of Wisconsin Medical School, Madison, Wisconsin, USA
    Ann Intern Med 142:451-66. 2005
    ..No consensus exists on the best methods for diagnosis of intravascular device (IVD)-related bloodstream infection...
  15. ncbi request reprint The role of the intensive care unit environment in the pathogenesis and prevention of ventilator-associated pneumonia
    Christopher J Crnich
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, University of Wisconsin Center for Health Sciences, Madison WI, USA
    Respir Care 50:813-36; discussion 836-8. 2005
    ..This review examines strategies to prevent transmission of environmental pathogens to the vulnerable mechanically-ventilated patient...
  16. pmc Nosocomial infection with vancomycin-dependent enterococci
    Paul A Tambyah
    University of Wisconsin Medical School, Madison, USA
    Emerg Infect Dis 10:1277-81. 2004
    ..While antimicrobial pressure promotes nosocomial colonization by VRE, prolonged exposure to vancomycin may foster the transition from vancomycin resistance to dependence...
  17. ncbi request reprint Use of vancomycin-containing lock or flush solutions for prevention of bloodstream infection associated with central venous access devices: a meta-analysis of prospective, randomized trials
    Nasia Safdar
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, Madison, WI, USA
    Clin Infect Dis 43:474-84. 2006
    ..We aimed to determine the efficacy of vancomycin-heparin lock or flush solution in preventing BSI in patients being treated with long-term central venous intravascular devices (IVDs)...
  18. doi request reprint Impact of switching from an open to a closed infusion system on rates of central line-associated bloodstream infection: a meta-analysis of time-sequence cohort studies in 4 countries
    Dennis G Maki
    University of Wisconsin School of Medicine and Public Health, Madison, USA
    Infect Control Hosp Epidemiol 32:50-8. 2011
    ....
  19. ncbi request reprint Does combination antimicrobial therapy reduce mortality in Gram-negative bacteraemia? A meta-analysis
    Nasia Safdar
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, Madison, USA
    Lancet Infect Dis 4:519-27. 2004
    ....
  20. ncbi request reprint The promise of novel technology for the prevention of intravascular device-related bloodstream infection. II. Long-term devices
    Christopher J Crnich
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, Madison, WI, USA
    Clin Infect Dis 34:1362-8. 2002
    ..The challenge for the future will be to identify new preventative technologies and to begin to more-widely adapt those technologies that have already been shown to be efficacious and cost effective...
  21. ncbi request reprint A review of risk factors for catheter-related bloodstream infection caused by percutaneously inserted, noncuffed central venous catheters: implications for preventive strategies
    Nasia Safdar
    Department of Medicine, University of Wisconsin Medical School and University of Wisconsin Hospitals and Clinics, Madison, 53792, USA
    Medicine (Baltimore) 81:466-79. 2002
    ....
  22. ncbi request reprint Are antimicrobial-impregnated catheters effective? When does repetition reach the point of exhaustion?
    Christopher J Crnich
    Department of Medicine, University of Wisconsin Hospital and Clinics, Medical School, Madison, WI 53792, USA
    Clin Infect Dis 41:681-5. 2005
  23. ncbi request reprint The pathogenesis of ventilator-associated pneumonia: its relevance to developing effective strategies for prevention
    Nasia Safdar
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, University of Wisconsin Center for Health Sciences, Madison WI, USA
    Respir Care 50:725-39; discussion 739-41. 2005
    ..Routine surveillance of VAP, to track endemic VAPs and facilitate early detection of outbreaks, is mandatory...
  24. ncbi request reprint Risk of catheter-related bloodstream infection with peripherally inserted central venous catheters used in hospitalized patients
    Nasia Safdar
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, Madison, USA
    Chest 128:489-95. 2005
    ..Data on the risk of PICC-related bloodstream infection (BSI) with PICCs used in hospitalized patients are limited...
  25. ncbi request reprint Risk of hemolytic uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 enteritis: a meta-analysis
    Nasia Safdar
    Department of Medicine, University of Wisconsin Medical School and University of Wisconsin Hospital and Clinics, Madison, WI 53792 5158, USA
    JAMA 288:996-1001. 2002
    ..However, other larger studies have reported a protective effect or no association...
  26. ncbi request reprint Inflammation at the insertion site is not predictive of catheter-related bloodstream infection with short-term, noncuffed central venous catheters
    Nasia Safdar
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, Madison, WI, USA
    Crit Care Med 30:2632-5. 2002
    ..S. hospitals each year. We report a prospective study to determine whether inflammation at the insertion site is predictive of CVC-related BSI...
  27. pmc Relationship of in vitro synergy and treatment outcome with daptomycin plus rifampin in patients with invasive methicillin-resistant Staphylococcus aureus infections
    Warren E Rose
    Pharmacy Practice Division, University of Wisconsin Madison School of Pharmacy, Madison, Wisconsin, USA
    Antimicrob Agents Chemother 57:3450-2. 2013
    ..045). No relationship was observed between synergy and outcome by time-kill assessment. Checkerboard synergy may predict clinical response to daptomycin plus rifampin for complex invasive MRSA infections requiring prolonged treatment...
  28. ncbi request reprint The effects of prolonged ethanol exposure on the mechanical properties of polyurethane and silicone catheters used for intravascular access
    Christopher J Crnich
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Hospital and Medical School, Madison, Wisconsin, USA
    Infect Control Hosp Epidemiol 26:708-14. 2005
    ..The effects of alcohol on the integrity of intravascular devices remain unknown...
  29. ncbi request reprint The commonality of risk factors for nosocomial colonization and infection with antimicrobial-resistant Staphylococcus aureus, enterococcus, gram-negative bacilli, Clostridium difficile, and Candida
    Nasia Safdar
    Department of Medicine, University of Wisconsin Hospital and Clinics, 600 Highland Avenue, H4 572, Madison, WI 53792, USA
    Ann Intern Med 136:834-44. 2002
    ....
  30. ncbi request reprint The promise of novel technology for the prevention of intravascular device-related bloodstream infection. I. Pathogenesis and short-term devices
    Christopher J Crnich
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, Madison, WI, USA
    Clin Infect Dis 34:1232-42. 2002
    ..The challenge for the future will be to identify new preventative technologies and to begin to adapt more widely those technologies already shown to be efficacious and cost-effective...
  31. pmc Comparison of culture screening methods for detection of nasal carriage of methicillin-resistant Staphylococcus aureus: a prospective study comparing 32 methods
    Nasia Safdar
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, Madison, Wisconsin, USA
    J Clin Microbiol 41:3163-6. 2003
    ..Direct inoculation of swabs onto MSAL(Ox) allows detection of 90% of MRSA carriers...
  32. pmc Severe Ehrlichia chaffeensis infection in a lung transplant recipient: a review of ehrlichiosis in the immunocompromised patient
    Nasia Safdar
    Section of Infectious Diseases, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792, USA
    Emerg Infect Dis 8:320-3. 2002
    ..Of 23 reported cases of ehrlichiosis in immunocompromised patients, organ failure occurred in all patients and 6 (25%) died...
  33. ncbi request reprint Don't eat the spinach--controlling foodborne infectious disease
    Dennis G Maki
    University of Wisconsin School of Medicine and Public Health, University of Wisconsin Hospital and Clinics, Madison, USA
    N Engl J Med 355:1952-5. 2006
  34. ncbi request reprint Conclusions: drotrecogin alfa (activated)--from bench to practical use at the bedside
    Dennis G Maki
    University of Wisconsin Hospital and Clinics, 600 Highland Avenue, H4 572, Madison, WI 53792, USA
    Am J Surg 184:S47-50. 2002
  35. ncbi request reprint The direct costs of nosocomial catheter-associated urinary tract infection in the era of managed care
    Paul A Tambyah
    Department of Medicine, University of Wisconsin Medical School, University of Wisconsin, Madison, USA
    Infect Control Hosp Epidemiol 23:27-31. 2002
    ..To determine the additional direct costs of hospitalization attributable to catheter-associated urinary tract infection (CAUTI) in 1,497 newly catheterized patients...
  36. ncbi request reprint Guidelines for the prevention of intravascular catheter-related infections
    NAOMI P O'GRADY
    Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
    Infect Control Hosp Epidemiol 23:759-69. 2002
    ..Although many catheter-related bloodstream infections (CRBSIs) are preventable, measures to reduce these infections are not uniformly implemented...
  37. ncbi request reprint Guidelines for the prevention of intravascular catheter-related infections. The Hospital Infection Control Practices Advisory Committee, Center for Disease Control and Prevention, U.S
    NAOMI P O'GRADY
    National Institutes of Health, Department of Critical Care Medicine, Bethesda, Maryland 20892, USA
    Pediatrics 110:e51. 2002
    ..These guidelines also identify performance indicators that can be used locally by health-care institutions or organizations to monitor their success in implementing these evidence-based recommendations...
  38. ncbi request reprint Device-associated nosocomial infections in 55 intensive care units of 8 developing countries
    Victor D Rosenthal
    Medical College of Buenos Aires, Buenos Aires, Argentina
    Ann Intern Med 145:582-91. 2006
    ..0 per 1000 CVC days, 5.4 per 1000 mechanical ventilator days, and 3.9 per Foley catheter days, respectively...
  39. ncbi request reprint Systemic host responses in severe sepsis analyzed by causative microorganism and treatment effects of drotrecogin alfa (activated)
    Steven M Opal
    Brown University School of Medicine, Providence, RI, USA
    Clin Infect Dis 37:50-8. 2003
    ..Results demonstrate that DrotAA, administered as an adjunct to standard anti-infective therapy, can improve the rate of survival for patients who develop severe sepsis regardless of causative microorganism...
  40. ncbi request reprint Lost in translation
    Nasia Safdar
    Infect Control Hosp Epidemiol 27:3-7. 2006
  41. ncbi request reprint Severe community-acquired pneumonia as a cause of severe sepsis: data from the PROWESS study
    Pierre Francois Laterre
    Head of Intensive Care Unit, Cliniques Universitaires Saint Luc Service des Urgences et des Soins Intensifs, UCL, Brussels, Belgium
    Crit Care Med 33:952-61. 2005
    ....
  42. ncbi request reprint Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control and Prevention
    NAOMI P O'GRADY
    National Institutes of Health, Bethesda, Maryland, USA
    MMWR Recomm Rep 51:1-29. 2002
    ..These guidelines also identify performance indicators that can be used locally by health-care institutions or organizations to monitor their success in implementing these evidence-based recommendations...
  43. ncbi request reprint Prospective study of the impact of open and closed infusion systems on rates of central venous catheter-associated bacteremia
    Victor D Rosenthal
    Infection Control and Infectious Diseases Department, Bernal Medical Center and Colegiales Medical Center, Arengreen 1366, 1405 Buenos Aires, Argentina
    Am J Infect Control 32:135-41. 2004
    ....
  44. ncbi request reprint Quality of care and satisfaction among patients isolated for infection control
    Nasia Safdar
    JAMA 291:420-1; author reply 421-2. 2004
  45. ncbi request reprint Effect of a second-generation venous catheter impregnated with chlorhexidine and silver sulfadiazine on central catheter-related infections: a randomized, controlled trial
    Mark E Rupp
    University of Nebraska Medical Center, Omaha, Nebraska, USA
    Ann Intern Med 143:570-80. 2005
    ..Central venous catheter-related infections are a significant medical problem. Improved preventive measures are needed...
  46. pmc Improving the safety of peripheral intravenous catheters
    Dennis G Maki
    BMJ 337:a630. 2008
  47. ncbi request reprint History forgotten is history relived: nosocomial infection control is also essential in the outpatient setting
    Dennis G Maki
    Arch Intern Med 165:2565-7. 2005
  48. ncbi request reprint The 2002 Hospital Infection Control Practices Advisory Committee Centers for Disease Control and Prevention guideline for prevention of intravascular device-related infection
    Jeffery S Garland
    Department of Pediatrics, St Joseph s Regional Medical Center, Milwaukee, WI 53210, USA
    Pediatrics 110:1009-13. 2002
  49. ncbi request reprint Guidelines for the prevention of intravascular catheter-related infections
    NAOMI P O'GRADY
    Clinical Center, National Institutes of Health, Bethesda, MD, USA
    Am J Infect Control 30:476-89. 2002
    ..Although many catheter-related bloodstream infections (CR-BSIs) are preventable, measures to reduce these infections are not uniformly implemented...
  50. ncbi request reprint Disinfection of needleless catheter connectors and access ports with alcohol may not prevent microbial entry: the promise of a novel antiseptic-barrier cap
    Steve Z Menyhay
    Menhay Medical, Fresno, California, USA
    Infect Control Hosp Epidemiol 27:23-7. 2006
    ....
  51. doi request reprint Guidelines for evaluation of new fever in critically ill adult patients: 2008 update from the American College of Critical Care Medicine and the Infectious Diseases Society of America
    NAOMI P O'GRADY
    National Institutes of Health, Bethesda, MD, USA
    Crit Care Med 36:1330-49. 2008
    ..To update the practice parameters for the evaluation of adult patients who develop a new fever in the intensive care unit, for the purpose of guiding clinical practice...