Research Topics
Genomes and Genes | Sharmila MajumdarSummaryAffiliation: University of California Country: USA Publications
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Publications
Diagnostic tools and imaging methods in intervertebral disk degenerationSharmila Majumdar
Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
Orthop Clin North Am 42:501-11, viii. 2011..With the potential for morphologic and biochemical characterization of the intervertebral disk, MRI shows promise as a tool to quantitatively assess disk health...
High-resolution computed tomography for clinical imaging of bone microarchitectureAndrew J Burghardt
Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, Campus Box 2520, QB3 Building, 2nd Floor, Suite 203, 1700 4th Street, San Francisco, CA 94158, USA
Clin Orthop Relat Res 469:2179-93. 2011..However, many technical and practical challenges remain to translate these techniques into established clinical outcomes...
Quantitative assessment of bone marrow edema-like lesion and overlying cartilage in knees with osteoarthritis and anterior cruciate ligament tear using MR imaging and spectroscopic imaging at 3 TeslaXiaojuan Li
Musculo skeletal Quantitative Imaging Research MQIR, Department of Radiology, University of California, San Francisco UCSF, San Francisco, California 94107, USA
J Magn Reson Imaging 28:453-61. 2008..To quantitatively assess bone marrow edema-like lesion (BMEL) and the overlying cartilage in osteoarthritis (OA) or anterior cruciate ligament (ACL)-injured knees using magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI)...
A longitudinal HR-pQCT study of alendronate treatment in postmenopausal women with low bone density: Relations among density, cortical and trabecular microarchitecture, biomechanics, and bone turnoverAndrew J Burghardt
Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA
J Bone Miner Res 25:2558-71. 2010..48, p < .05). These findings suggest a more pronounced response to ALN in the tibia than in the radius, driven by trabecular and endocortical changes...
Longitudinal evaluation of the effects of alendronate on MRI bone microarchitecture in postmenopausal osteopenic womenJenny Folkesson
Musculoskeletal Quantitative Imaging Research Group MQIR, Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA
Bone 48:611-21. 2011..Treatment effects were observed in the distal tibia after 24 months. The BE-FCM method increased correlations to HR-pQCT-based parameters...
Fuzzy logic structure analysis of trabecular bone of the calcaneus to estimate proximal femur fracture load and discriminate subjects with and without vertebral fractures using high-resolution magnetic resonance imaging at 1.5 T and 3 TPriyesh V Patel
Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
Calcif Tissue Int 81:294-304. 2007..Local femoral measurements are still needed to estimate femoral bone strength. Overall, parameters obtained at 3.0 T performed better than those at 1.5 T...
Proximal femur specimens: automated 3D trabecular bone mineral density analysis at multidetector CT--correlation with biomechanical strength measurementMarkus B Huber
Musculoskeletal and Quantitative Imaging Research, Department of Radiology, University of California, San Francisco, 185 Berry St, Suite 350, San Francisco, CA 94107, USA
Radiology 247:472-81. 2008....
IGF-I receptor is required for the anabolic actions of parathyroid hormone on boneYongmei Wang
Department of Medicine, Endocrine Unit, Veterans Affairs Medical Center, San Francisco, California 94121, USA
J Bone Miner Res 22:1329-37. 2007..We showed that the IGF-IR-null mutation in mature osteoblasts leads to less bone and decreased periosteal bone formation and impaired the stimulatory effects of PTH on osteoprogenitor cell proliferation and differentiation...
Rapid in vivo musculoskeletal MR with parallel imaging at 7TSuchandrima Banerjee
Radiology, University of California, San Francisco, San Francisco, California 94158, USA
Magn Reson Med 59:655-60. 2008..Robust quantification of bone and cartilage metrics could be derived from accelerated ankle and knee acquisitions. PI can enhance the clinical feasibility of in vivo bone and cartilage HR-MRI for osteoporosis and osteoarthritis at 7T...
Insulin-like growth factor I stimulates recovery of bone lost after a period of skeletal unloadingBenjamin M Boudignon
Division of Endocrinology, Veterans Affairs Medical Center, and Department of Medicine, University of California, San Francisco, California, USA
J Appl Physiol 103:125-31. 2007....
Comparison of clinical semi-quantitative assessment of muscle fat infiltration with quantitative assessment using chemical shift-based water/fat separation in MR studies of the calf of post-menopausal womenHamza Alizai
Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry Street, Suite 350, San Francisco, CA 94107, USA
Eur Radiol 22:1592-600. 2012..The goal of this study was to compare the semi-quantitative Goutallier classification for fat infiltration with quantitative fat-fraction derived from a magnetic resonance imaging (MRI) chemical shift-based water/fat separation technique...
Inter-subject comparison of MRI knee cartilage thicknessJulio Carballido-Gamio
MQIR, Department of Radiology, University of California, QB3 Building, 2nd Floor, 201, 1700 4th Street, San Francisco, CA 94158, USA
Med Image Anal 12:120-35. 2008..Results showed that the proposed technique is robust, accurate, and reproducible to perform point to point inter-subject comparison of knee cartilage thickness values...
Longitudinal analysis of MRI T(2) knee cartilage laminar organization in a subset of patients from the osteoarthritis initiativeJulio Carballido-Gamio
Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, USA
Magn Reson Med 63:465-72. 2010..Further investigation is warranted to evaluate the potential of the presented methodology to better characterize evolution and pathophysiology of osteoarthritis...
Relationship between trabecular bone structure and articular cartilage morphology and relaxation times in early OA of the knee joint using parallel MRI at 3 TR I Bolbos
Musculoskeletal Quantitative Imaging Research, Department of Radiology, University of California San Francisco, San Francisco, CA 94107, USA
Osteoarthritis Cartilage 16:1150-9. 2008..To evaluate trabecular bone structure in relationship with cartilage parameters in distal femur and proximal tibia of the human knee at 3Tesla (3T) using high-resolution magnetic resonance imaging (MRI) with parallel imaging...
Elliptical magnetic resonance spectroscopic imaging with GRAPPA for imaging brain tumors at 3 TSuchandrima Banerjee
Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA
Magn Reson Imaging 27:1319-25. 2009..Metabolite concentrations measured from the accelerated acquisitions were in good agreement with measurements obtained from fully sampled MRSI scans...
Age- and gender-related differences in the geometric properties and biomechanical significance of intracortical porosity in the distal radius and tibiaAndrew J Burghardt
Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
J Bone Miner Res 25:983-93. 2010..The biomechanical significance of these structural differences increases with age for men and women and provides discriminatory information for menopause-related bone quality effects...
Spatial distribution and relationship of T1rho and T2 relaxation times in knee cartilage with osteoarthritisXiaojuan Li
Musculoskeletal Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, San Francisco, California 94107, USA
Magn Reson Med 61:1310-8. 2009..T(1rho) and T(2) values show different spatial distributions and may provide complementary information regarding cartilage degeneration in OA...
Ultrashort echo time MRI of cortical bone at 7 tesla field strength: a feasibility studyRoland Krug
Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
J Magn Reson Imaging 34:691-5. 2011..To implement and examine the feasibility of a three-dimensional (3D) ultrashort TE (UTE) sequence on a 7 Tesla (T) clinical MR scanner in comparison with 3T MRI at high isotropic resolution...
In vivo bone and cartilage MRI using fully-balanced steady-state free-precession at 7 teslaRoland Krug
Department of Radiology, University of California, San Francisco, San Francisco, California, USA
Magn Reson Med 58:1294-8. 2007..3) compared with 3T (21.3 +/- 3.3). Bone SNR increased from 11.8 +/- 2.0 to 13.2 +/- 2.5 at the higher field strength. We concluded that there is SNR benefit and great potential for bone and cartilage imaging at higher field strength...
Local bone enhancement fuzzy clustering for segmentation of MR trabecular bone imagesJenny Folkesson
Department of Radiology and Biomedical Imaging, Musculoskeletal and Quantitative Imaging Research Group MQIR, University of California, San Francisco, California 94158, USA
Med Phys 37:295-302. 2010..This approach is meant to allow for a soft segmentation that accounts for partial volume effects while suppressing the influence of noise...
GRAPPA-based susceptibility-weighted imaging of normal volunteers and patients with brain tumor at 7 TJanine M Lupo
Department of Radiology, Surbeck Laboratory of Advanced Imaging, University of California, San Francisco, CA 94158 2532, USA
Magn Reson Imaging 27:480-8. 2009..GRAPPA-based SWI at 7 T revealed regions of microvascularity, hemorrhage and calcification within heterogeneous brain tumors that may aid in characterizing active or necrotic tumor and monitoring treatment effects...
Three-dimensional image registration of MR proximal femur images for the analysis of trabecular bone parametersJanet Blumenfeld
Department of Radiology and UCSF UCB Joint Graduate Group in Bioengineering, University of California, San Francisco, San Francisco, California 94107, USA
Med Phys 35:4630-9. 2008....
Variations in morphological and biomechanical indices at the distal radius in subjects with identical BMDGalateia J Kazakia
Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, 185 Berry Street, San Francisco, CA, USA
J Biomech 44:257-66. 2011..Overlap of these indices among osteoporotic status groups reflects the reported incidence of osteoporotic fracture in subjects classified as osteopenic or normal...
Volumetric cartilage measurements of porcine knee at 1.5-T and 3.0-T MR imaging: evaluation of precision and accuracyJan S Bauer
Musculoskeletal and Quantitative Imaging Research, Department of Radiology, University of California, San Francisco, Calif, USA
Radiology 241:399-406. 2006..To compare the precision and accuracy of 3.0-T and 1.5-T magnetic resonance (MR) imaging in the quantification of cartilage volume by using direct volumetric measurements as a reference standard...
In vivo 3T spiral imaging based multi-slice T(1rho) mapping of knee cartilage in osteoarthritisXiaojuan Li
Musculo skeletal Quantitative Imaging Research MQIR, Department of Radiology, University of California, San Francisco UCSF, 94107, USA
Magn Reson Med 54:929-36. 2005..The results suggest that T(1rho) relaxation times may be a promising clinical tool for osteoarthritis detection and treatment monitoring...
Chemical shift-based water/fat separation in the presence of susceptibility-induced fat resonance shiftDimitrios C Karampinos
Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California, USA
Magn Reson Med 68:1495-505. 2012..The technique is validated in a phantom and preliminary in vivo results are shown in the calf musculature of healthy and diabetic subjects...
Effects of unloading on knee articular cartilage T1rho and T2 magnetic resonance imaging relaxation times: a case seriesRichard B Souza
Department of Physical Therapy and Rehabilitation Science, University of California, San Francisco, San Francisco, CA, USA
J Orthop Sports Phys Ther 42:511-20. 2012..Case series...
Characterization of the regional distribution of skeletal muscle adipose tissue in type 2 diabetes using chemical shift-based water/fat separationDimitrios C Karampinos
Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA
J Magn Reson Imaging 35:899-907. 2012....
Magnetic resonance imaging of in vivo kinematics after total knee arthroplastyKeh Yang Lee
Department of Radiology, University of California at San Francisco, San Francisco, California 94143 0946, USA
J Magn Reson Imaging 21:172-8. 2005....
Quantitative MRI using T1ρ and T2 in human osteoarthritic cartilage specimens: correlation with biochemical measurements and histologyXiaojuan Li
Department of Radiology and Biomedical Imaging, Musculoskeletal and Quantitative Imaging Research, University of California, San Francisco UCSF, CA 94107, USA
Magn Reson Imaging 29:324-34. 2011..We aimed to investigate the orientation effect on T(1ρ) and T(2) values in human osteoarthritic cartilage and to quantify the correlation between T(1ρ), T(2) vs. biochemical composition and histology in human osteoarthritic cartilage...
Assessment of intervertebral disc degeneration with magnetic resonance single-voxel spectroscopyJin Zuo
Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California, USA
Magn Reson Med 62:1140-6. 2009..0039). This study demonstrates for the first time that short-echo PRESS on a clinical 3T MR scanner can be used to noninvasively and can reproducibly quantify metabolic changes associated with degeneration of intervertebral discs...
7T human spine imaging arrays with adjustable inductive decouplingBing Wu
Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA
IEEE Trans Biomed Eng 57:397-403. 2010..Preliminary results of human spine images acquired using the transceiver arrays demonstrate the feasibility of the design for ultrahigh-field MR applications and its robust performance for parallel imaging...
Quantitative analysis of spatial distortions of diffusion techniques at 3TDuan Xu
Department of Radiology and Biomedical Imaging, University of California San Francisco, CA, USA
Magn Reson Imaging 28:451-4. 2010..These methods have confirmed the SSFSE based diffusion method is less distorted than the EPI based one, which is generally accepted through visual inspection...
Geodesic topological analysis of trabecular bone microarchitecture from high-spatial resolution magnetic resonance imagesJulio Carballido-Gamio
Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, San Francisco, California 94158, USA
Magn Reson Med 61:448-56. 2009..95; p < 0.001). Results indicate that GTA can substantially contribute in studies of osteoporosis involving imaging of the trabecular bone microarchitecture...
High-resolution peripheral quantitative computed tomographic imaging of cortical and trabecular bone microarchitecture in patients with type 2 diabetes mellitusAndrew J Burghardt
Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, QB3 Building, Suite 203, San Francisco, California 94158, USA
J Clin Endocrinol Metab 95:5045-55. 2010..Cross-sectional epidemiological studies have found that patients with type 2 diabetes mellitus (T2DM) have a higher incidence of certain fragility fractures despite normal or elevated bone mineral density (BMD)...
Interrelationships between 3-T-MRI-derived cortical and trabecular bone structure parameters and quantitative-computed-tomography-derivedbone mineral densityAhi Sema Issever
Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, China Basin, San Francisco, CA 94107, USA
Magn Reson Imaging 28:1299-305. 2010..Furthermore, within the first 10 mm at the radius, an inverse correlation for Ct.Th and app. BV/TV (r(6mm)=-.56, P<.001; r(10mm)=-.36, P<.05) and app. Tb.Th (r(6mm)=-.54, P<.001; r(10mm)=-.41, P<.05) was found...
Prospective image registration for automated scan prescription of follow-up knee images in quantitative studiesJanet Goldenstein
Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94158, USA
Magn Reson Imaging 29:693-700. 2011..Results show an improvement with prospective registration in the coefficient of variation for cartilage thickness, cartilage volume and T2 relaxation measurements...
Partially-parallel, susceptibility-weighted MR imaging of brain vasculature at 7 Tesla using sensitivity encoding and an autocalibrating parallel techniqueJanine M Lupo
University of California San Francisco, CA, USA
Conf Proc IEEE Eng Med Biol Soc 1:747-50. 2006....
Diagnostic performance of in vivo 3-T MRI for articular cartilage abnormalities in human osteoarthritic knees using histology as standard of referenceEhsan Saadat
School of Medicine and Department of Radiology, University of California San Francisco, San Francisco, CA, USA
Eur Radiol 18:2292-302. 2008....
Prevalence of pathologic findings in asymptomatic knees of marathon runners before and after a competition in comparison with physically active subjects-a 3.0 T magnetic resonance imaging studyRobert Stahl
Musculoskeletal and Quantitative Imaging Group, Department of Radiology, University of California, San Francisco, 185 Berry Street, Suite 350, San Francisco, CA 94107 0946, USA
Skeletal Radiol 37:627-38. 2008..To compare the diagnostic performance of cartilage-dedicated magnetic resonance imaging (MRI) sequences at 3.0 T...
Lactic acid and proteoglycans as metabolic markers for discogenic back painKayvan R Keshari
Department of Radiology, University of California, San Francisco, CA 94158 2330, USA
Spine (Phila Pa 1976) 33:312-7. 2008..These samples were then analyzed using ex vivo proton high resolution magic angle spinning (HR-MAS) NMR spectroscopy to produce metabolic profiles for comparison between the 2 patient groups...
Analysis of trabecular bone structure with multidetector spiral computed tomography in a simulated soft-tissue environmentJan S Bauer
Musculoskeletal and Quantitative Imaging Research, Department of Radiology, University of California in San Francisco, San Francisco, CA, USA
Calcif Tissue Int 80:366-73. 2007..Even though ST scatter compromises image quality substantially, the major characteristics of the trabecular network can still be appreciated and quantified...
Wavelet-based characterization of vertebral trabecular bone structure from magnetic resonance images at 3 T compared with micro-computed tomographic measurementsRoland Krug
MQIR, Department of Radiology, University of California, San Francisco, CA 94143 2520, USA
Magn Reson Imaging 25:392-8. 2007....
A feasibility study of in vivo T1rho imaging of the intervertebral discGabrielle Blumenkrantz
Department of Radiology, University of California San Francisco, QB3 Building, Box 2520, San Francisco, CA 94158, USA
Magn Reson Imaging 24:1001-7. 2006..The purpose of this study was to test the feasibility of quantifying T1rho relaxation time in phantoms and intervertebral discs of healthy volunteers using in vivo MR imaging at 3 T...
Feasibility and reproducibility of relaxometry, morphometric, and geometrical measurements of the hip joint with magnetic resonance imaging at 3TJulio Carballido-Gamio
Department of Radiology, University of California San Francisco, 1700 4th Street, San Francisco, CA 94158, USA
J Magn Reson Imaging 28:227-35. 2008..To test the feasibility of in vivo magnetic resonance T(1rho) relaxation time measurements of hip cartilage, and quantify the reproducibility of hip cartilage thickness, volume, T(2), T(1rho), and size of femoral head measurements...
Flexible transceiver array for ultrahigh field human MR imagingBing Wu
Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California 94158, USA
Magn Reson Med 68:1332-8. 2012..Seven Tesla parallel imaging with generalized autocalibrating partially parallel acquisitions (GRAPPA) performed using this flexible transceiver array was also presented...
In vivo intervertebral disc characterization using magnetic resonance spectroscopy and T1ρ imaging: association with discography and Oswestry Disability Index and Short Form-36 Health SurveyJin Zuo
Department of Radiology and Biomedical Imaging, University of California, San Francisco, USA
Spine (Phila Pa 1976) 37:214-21. 2012..An in vivo study of intervertebral disc degeneration by using quantitative magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS)...
MRI analysis of in vivo meniscal and tibiofemoral kinematics in ACL-deficient and normal kneesSandra J Shefelbine
Department of Orthopaedic Surgery, University of California, San Francisco, 500 Parnassus Avenue, MU 320W, San Francisco, California 94143-0728, USA
J Orthop Res 24:1208-17. 2006..These results help explain the increased risk of meniscal tears and osteoarthritis in chronic ACL deficient knees...
Magnetic resonance imaging of in vivo patellofemoral kinematics after total knee arthroplastyR Dana Carpenter
Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143 0946, USA
Knee 16:332-6. 2009..These results suggest that the patellar component in BCS TKA may be expected to experience less wear than the patellar component in PCR TKA over time...
In vivo ultra-high-field magnetic resonance imaging of trabecular bone microarchitecture at 7 TRoland Krug
Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
J Magn Reson Imaging 27:854-9. 2008....
Gender differences in the response of CD-1 mouse bone to parathyroid hormone: potential role of IGF-IYongmei Wang
Department of Medicine, Endocrine Unit, Veterans Affairs Medical Center, University of California, San Francisco, California 94117-1080, USA
J Endocrinol 189:279-87. 2006..These effects are more evident in the male mouse. These differences between male and female mice may reflect the greater response to PTH of IGF-I and IGF-IR gene expression in males enhancing the anabolic effect on cortical bone...
Computer-aided quantification of focal cartilage lesions of osteoarthritic knee using MRIKeh Yang Lee
Department of Radiology, University of California, San Francisco, San Francisco, California, USA
Magn Reson Imaging 22:1105-15. 2004....
T1rho, T2 and focal knee cartilage abnormalities in physically active and sedentary healthy subjects versus early OA patients--a 3.0-Tesla MRI studyRobert Stahl
Department of Radiology, University of California, San Francisco, CA 94107 0946, USA
Eur Radiol 19:132-43. 2009..Thus, T1rho and T2 could be a parameter suited to identify active healthy subjects at higher risk for developing cartilage pathology...
Assessment of cartilage-dedicated sequences at ultra-high-field MRI: comparison of imaging performance and diagnostic confidence between 3.0 and 7.0 T with respect to osteoarthritis-induced changes at the knee jointRobert Stahl
Musculoskeletal and Quantitative Imaging Group, Department of Radiology, University of California, San Francisco, CA 94107 0946, USA
Skeletal Radiol 38:771-83. 2009..0 T ultra-high-field (UHF) magnetic resonance imaging (MRI) and to compare imaging performance and diagnostic confidence concerning osteoarthritis (OA)-induced changes at 7.0 and 3.0 T MRI...
Single-shot fast spin-echo diffusion tensor imaging of the lumbar spine at 1.5 and 3 TJulio Carballido-Gamio
Department of Radiology, University of California San Francisco, CA 94158, USA
Magn Reson Imaging 25:665-70. 2007..Results indicate that DTI-SSFSE is a candidate as a clinical sequence for obtaining diffusion tensor images of the lumbar intervertebral discs with scan times shorter than 4 min...
A three-dimensional MRI analysis of knee kinematicsVikas V Patel
Department of Orthopaedic Surgery, University of California, San Francisco, CA 94143, USA
J Orthop Res 22:283-92. 2004..MR imaging allows excellent non-invasive evaluation of knee joint kinematics with weight bearing. This tool may potentially be used for assessing knee kinematics in patients with knee pathology...
MR imaging findings in the follow-up of patients with different stages of knee osteoarthritis and the correlation with clinical symptomsCatherine M Phan
Department of Radiology, University of California San Francisco, 185 Berry Street, Suite 350, Box 0628, San Francisco, CA 94143 0946, USA
Eur Radiol 16:608-18. 2006..5-T MRI in patients with knee osteoarthritis and to correlate these findings with the clinical Western Ontario and McMaster University Osteoarthitis (WOMAC) score...
A pilot, two-year longitudinal study of the interrelationship between trabecular bone and articular cartilage in the osteoarthritic kneeGabrielle Blumenkrantz
Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, CA 94107, USA
Osteoarthritis Cartilage 12:997-1005. 2004..To examine the relationship between structural changes of trabecular bone and cartilage, in patients with varying degrees of osteoarthritis (OA) over 2 years, using magnetic resonance imaging...
Cartilage MR imaging at 3.0 versus that at 1.5 T: preliminary results in a porcine modelJeffrey N Masi
Department of Radiology, University of California, San Francisco, 400 Parnassus Ave, A 367, Box 0628, San Francisco, CA 94143-0628, USA
Radiology 236:140-50. 2005..0 T (P < .05). CONCLUSION: In this animal model, MR imaging at 3.0 T increased the accuracy of cartilage lesion assessment when compared with imaging at 1.5 T. Image quality and SNR were highest at 3.0 T...
Meniscal measurements of T1rho and T2 at MR imaging in healthy subjects and patients with osteoarthritisIsabel Rauscher
Department of Radiology, University of California, San Francisco, San Francisco, CA 94143 0628, USA
Radiology 249:591-600. 2008....
In vivo determination of bone structure in postmenopausal women: a comparison of HR-pQCT and high-field MR imagingGalateia J Kazakia
Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, California 94158, USA
J Bone Miner Res 23:463-74. 2008..Significant but moderate correlations and 2- to 4-fold discrepancies in parameter values were detected, suggesting that differences in acquisition and analysis must be considered when interpreting data from these imaging modalities...
Morphology of the human vertebral endplateAzucena G Rodriguez
Department of Orthopaedic Surgery, University of California, San Francisco, California 94143, USA
J Orthop Res 30:280-7. 2012..Since ischemic disc cell behavior is commonly associated with degenerative change, this may be related to other factors such as the quality of vertebral capillaries, as opposed to decreased permeability of intervening tissues...
Current diagnostic techniques in the evaluation of bone architectureThomas M Link
Department of Radiology, University of California, San Francisco, 400 Parnassus Avenue A 367, Box 0628, San Francisco, CA 94143, USA
Curr Osteoporos Rep 2:47-52. 2004..The methodologies described will include magnetic resonance imaging, clinical multislice spiral computed tomography, and micro-computed tomography, along with computerized analysis of radiographic patterns of trabecular bone...
Cartilage in anterior cruciate ligament-reconstructed knees: MR imaging T1{rho} and T2--initial experience with 1-year follow-upXiaojuan Li
Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, China Basin Landing, 185 Berry St, Suite 350, San Francisco, CA 94107, USA xiaojuan li
Radiology 258:505-14. 2011....
In vivo T1rho quantitative assessment of knee cartilage after anterior cruciate ligament injury using 3 Tesla magnetic resonance imagingRadu I Bolbos
Musculo skeletal Quantitative Imaging Research, Department of Radiology, University of California, San Francisco, San Francisco, California 94107, USA
Invest Radiol 43:782-8. 2008....
Randomized trial of once-weekly parathyroid hormone (1-84) on bone mineral density and remodelingDennis M Black
Department of Epidemiology and Biostatistics, University of California San Francisco, 185 Berry Street, San Francisco, CA 94107, USA
J Clin Endocrinol Metab 93:2166-72. 2008..Daily PTH administration increases bone mineral density (BMD) and reduces fracture risk. However, cost and compliance significantly limit clinical use...
Imaging of the musculoskeletal system in vivo using ultra-high field magnetic resonance at 7 TRoland Krug
Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA
Invest Radiol 44:613-8. 2009..Imaging of more central body parts such as the spine at 7 T is still in its infancy and dedicated coils have to be developed...
Magnetic resonance imaging of 3-dimensional in vivo tibiofemoral kinematics in anterior cruciate ligament-reconstructed kneesR Dana Carpenter
Department of Radiology, University of California, San Francisco, California 94143, USA
Arthroscopy 25:760-6. 2009..The purpose of this study was to use magnetic resonance imaging (MRI) to determine 3-dimensional knee kinematics after anterior cruciate ligament (ACL) reconstruction...
Evaluation of correction methods for coil-induced intensity inhomogeneities and their influence on trabecular bone structure parameters from MR imagesJenny Folkesson
Department of Radiology and Biomedical Imaging, Musculoskeletal and Quantitative Imaging Research Group MQIR, University of California, San Francisco, California 94158, USA
Med Phys 36:1267-74. 2009....
Magnetic resonance T(1 rho) imaging of osteoarthritis: a rabbit ACL transection modelJesus Lozano
University of California, San Francisco School of Medicine, San Francisco, CA 94158, USA
Magn Reson Imaging 27:611-6. 2009....
Regional variations of gender-specific and age-related differences in trabecular bone structure of the distal radius and tibiaMiki Sode
Joint Graduate Group in Bioengineering, University of California, San Francisco, CA, USA
Bone 46:1652-60. 2010..Therefore, a combined approach of investigating the entire region, each subregion, and the cortical compartment may offer more complete information...
Quantitative assessment of bone tissue mineralization with polychromatic micro-computed tomographyAndrew J Burghardt
Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94158, USA
Calcif Tissue Int 83:129-38. 2008..80). In cortical bone specimens, the correlation was somewhat weaker when a global threshold was applied (R (2) = 0.67) compared to the local threshold method (R (2) = 0.78)...
