S Majumdar

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint In vivo assessment of trabecular bone structure using fractal analysis of distal radius radiographs
    S Majumdar
    Department of Radiology, University of California, San Francisco 94143 1290, USA
    Med Phys 27:2594-9. 2000
  2. ncbi request reprint Current technologies in the evaluation of bone architecture
    Sharmila Majumdar
    Department of Radiology, MRSC, Box 1290, AC 109, 1 Irving Street, University of California, San Francisco, CA 94143, USA
    Curr Osteoporos Rep 1:105-9. 2003
  3. ncbi request reprint High-resolution magnetic resonance imaging: three-dimensional trabecular bone architecture and biomechanical properties
    S Majumdar
    Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco 94143 1290, USA
    Bone 22:445-54. 1998
  4. ncbi request reprint Trabecular bone architecture in the distal radius using magnetic resonance imaging in subjects with fractures of the proximal femur. Magnetic Resonance Science Center and Osteoporosis and Arthritis Research Group
    S Majumdar
    Department of Radiology, and Department of Internal Medicine, University of California, San Francisco, California, USA
    Osteoporos Int 10:231-9. 1999
  5. ncbi request reprint Fractal analysis of radiographs: assessment of trabecular bone structure and prediction of elastic modulus and strength
    S Majumdar
    Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco 94143, USA
    Med Phys 26:1330-40. 1999
  6. ncbi request reprint Anisotropy of the elastic modulus of trabecular bone specimens from different anatomical locations
    P Augat
    Department of Radiology, University of California, San Francisco 94143, USA
    Med Eng Phys 20:124-31. 1998
  7. pmc The feasibility of characterizing the spatial distribution of cartilage T(2) using texture analysis
    G Blumenkrantz
    Department of Radiology, University of California San Francisco, San Francisco, CA, USA
    Osteoarthritis Cartilage 16:584-90. 2008
  8. ncbi request reprint Assessment of trabecular bone structure comparing magnetic resonance imaging at 3 Tesla with high-resolution peripheral quantitative computed tomography ex vivo and in vivo
    R Krug
    Department of Radiology, University of California, San Francisco, CA, USA
    Osteoporos Int 19:653-61. 2008
  9. ncbi request reprint 3.0 vs 1.5 T MRI in the detection of focal cartilage pathology--ROC analysis in an experimental model
    T M Link
    Department of Radiology, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    Osteoarthritis Cartilage 14:63-70. 2006
  10. pmc Trabecular bone structure and spatial differences in articular cartilage MR relaxation times in individuals with posterior horn medial meniscal tears
    D Kumar
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
    Osteoarthritis Cartilage 21:86-93. 2013

Collaborators

Detail Information

Publications111 found, 100 shown here

  1. ncbi request reprint In vivo assessment of trabecular bone structure using fractal analysis of distal radius radiographs
    S Majumdar
    Department of Radiology, University of California, San Francisco 94143 1290, USA
    Med Phys 27:2594-9. 2000
    ....
  2. ncbi request reprint Current technologies in the evaluation of bone architecture
    Sharmila Majumdar
    Department of Radiology, MRSC, Box 1290, AC 109, 1 Irving Street, University of California, San Francisco, CA 94143, USA
    Curr Osteoporos Rep 1:105-9. 2003
    ..The methodologies described include micro-computed tomography, magnetic resonance imaging, and computerized analysis of radiographic patterns of trabecular bone...
  3. ncbi request reprint High-resolution magnetic resonance imaging: three-dimensional trabecular bone architecture and biomechanical properties
    S Majumdar
    Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco 94143 1290, USA
    Bone 22:445-54. 1998
    ..Further studies are clearly warranted to establish the role of architecture in predicting overall bone quality, and the role of trabecular architecture measures in clinical practice. (ABSTRACT TRUNCATED)..
  4. ncbi request reprint Trabecular bone architecture in the distal radius using magnetic resonance imaging in subjects with fractures of the proximal femur. Magnetic Resonance Science Center and Osteoporosis and Arthritis Research Group
    S Majumdar
    Department of Radiology, and Department of Internal Medicine, University of California, San Francisco, California, USA
    Osteoporos Int 10:231-9. 1999
    ..87) when radius and calcaneus structure was included. Measures of trabecular architecture derived from MR images combined with BMD measures improve the discrimination between subjects with hip fractures and normal age-matched controls...
  5. ncbi request reprint Fractal analysis of radiographs: assessment of trabecular bone structure and prediction of elastic modulus and strength
    S Majumdar
    Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco 94143, USA
    Med Phys 26:1330-40. 1999
    ..Thus, fractal based texture analysis of radiographs are technique dependent, but may be used to quantify trabecular structure and have a potentially valuable impact in the study of osteoporosis...
  6. ncbi request reprint Anisotropy of the elastic modulus of trabecular bone specimens from different anatomical locations
    P Augat
    Department of Radiology, University of California, San Francisco 94143, USA
    Med Eng Phys 20:124-31. 1998
    ..The data suggest that BMD can be most successfully applied to determine the mechanical properties in the principal loading direction, which from a clinical perspective may be most relevant...
  7. pmc The feasibility of characterizing the spatial distribution of cartilage T(2) using texture analysis
    G Blumenkrantz
    Department of Radiology, University of California San Francisco, San Francisco, CA, USA
    Osteoarthritis Cartilage 16:584-90. 2008
    ....
  8. ncbi request reprint Assessment of trabecular bone structure comparing magnetic resonance imaging at 3 Tesla with high-resolution peripheral quantitative computed tomography ex vivo and in vivo
    R Krug
    Department of Radiology, University of California, San Francisco, CA, USA
    Osteoporos Int 19:653-61. 2008
    ..Comparing HR-pQCT with MRI, we found that both modalities are capable of offering meaningful information on trabecular structure...
  9. ncbi request reprint 3.0 vs 1.5 T MRI in the detection of focal cartilage pathology--ROC analysis in an experimental model
    T M Link
    Department of Radiology, University of California, San Francisco, San Francisco, CA 94143 0628, USA
    Osteoarthritis Cartilage 14:63-70. 2006
    ..To use receiver operator characteristics (ROC) analysis for assessing the diagnostic performance of three cartilage-specific MR sequences at 1.5 and 3 T in detecting cartilage lesions created in porcine knees...
  10. pmc Trabecular bone structure and spatial differences in articular cartilage MR relaxation times in individuals with posterior horn medial meniscal tears
    D Kumar
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
    Osteoarthritis Cartilage 21:86-93. 2013
    ..To analyze knee trabecular bone structure and spatial cartilage T(1ρ) and T(2) relaxation times using 3-T magnetic resonance imaging (MRI) in subjects with and without tears of posterior horn of the medial meniscus (PHMM)...
  11. ncbi request reprint High resolution MRI of small joints: impact of spatial resolution on diagnostic performance and SNR
    T M Link
    Magnetic Resonance Science Center and Musculoskeletal Radiology, Department of Radiology, UCSF, San Francisco, CA, USA
    Magn Reson Imaging 16:147-55. 1998
    ..In conclusion this study shows that increasing spatial resolution improves diagnostic performance in cartilage lesions, though SNR decreases substantially. Assessment of correct lesion size and depth still is limited...
  12. ncbi request reprint New model-independent measures of trabecular bone structure applied to in vivo high-resolution MR images
    A Laib
    Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco 94143 1290, USA
    Osteoporos Int 13:130-6. 2002
    ..003). We conclude that in vivo high-resolution MRI not only has the potential of imaging trabecular bone, but in combination with novel metrics may offer new insight into the structural changes occurring in postmenopausal women...
  13. ncbi request reprint MRI-derived T2 relaxation times and cartilage morphometry of the tibio-femoral joint in subjects with and without osteoarthritis during a 1-year follow-up
    R Stahl
    Department of Radiology, University of California, San Francisco, 185 Berry Street, Suite 350, San Francisco, CA 94107 0946, USA
    Osteoarthritis Cartilage 15:1225-34. 2007
    ....
  14. pmc In vivo T(1rho) and T(2) mapping of articular cartilage in osteoarthritis of the knee using 3 T MRI
    X Li
    Musculo skeletal Quantitative Imaging Research, Department of Radiology, University of California at San Francisco, San Francisco, CA 94107, USA
    Osteoarthritis Cartilage 15:789-97. 2007
    ..The objective of this study was to determine the ability of MR T1rho (T(1rho)) and T(2) mapping to detect cartilage matrix degeneration between normal and early OA patients...
  15. ncbi request reprint Autocalibrating parallel imaging of in vivo trabecular bone microarchitecture at 3 Tesla
    S Banerjee
    Department of Radiology, University of California San Francisco, San Francisco, California 94158, USA
    Magn Reson Med 56:1075-84. 2006
    ..The results also demonstrated the potential of PPI for increasing the signal-to-noise ratio (SNR) efficiency of multiple-acquisition b-SSFP imaging protocols...
  16. ncbi request reprint Noninvasive assessment of bone density and structure using computed tomography and magnetic resonance
    T Lang
    Department of Radiology, University of California, San Francisco, 94143 1250, USA
    Bone 22:149S-153S. 1998
    ..High resolution MR measurements may be employed for assessment of the trabecular texture at a range of peripheral sites, including the calcaneus, distal radius, and phalanges...
  17. pmc Bone and cartilage demonstrate changes localized to bone marrow edema-like lesions within osteoarthritic knees
    G J Kazakia
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94107, USA
    Osteoarthritis Cartilage 21:94-101. 2013
    ..The aim of the present study was to evaluate bone structure and composition within bone marrow edema-like lesion (BMEL) regions associated with knee OA...
  18. ncbi request reprint In vivo assessment of architecture and micro-finite element analysis derived indices of mechanical properties of trabecular bone in the radius
    D C Newitt
    Magnetic Resonance Science Center, University of California, San Francisco 94143 1290, USA
    Osteoporos Int 13:6-17. 2002
    ..This study demonstrates the feasibility and potential of using MR imaging with microFE modeling in vivo in the study of osteoporosis...
  19. ncbi request reprint Processing and analysis of in vivo high-resolution MR images of trabecular bone for longitudinal studies: reproducibility of structural measures and micro-finite element analysis derived mechanical properties
    D C Newitt
    MRSC, Department of Radiology, University of California, San Francisco 94143 1290, USA
    Osteoporos Int 13:278-87. 2002
    ....
  20. ncbi request reprint Development and testing of texture discriminators for the analysis of trabecular bone in proximal femur radiographs
    M B Huber
    Department of Radiology and Biomedical Imaging, University of California, 400 Parnassus Avenue, San Francisco, California 94143, USA
    Med Phys 36:5089-98. 2009
    ..The goal of this in vitro study was to automatically place ROIs in radiographs of proximal femur specimens and to calculate correlations between various different texture analysis methods and the femurs' anchorage strength...
  21. pmc Association of MR relaxation and cartilage deformation in knee osteoarthritis
    K Subburaj
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94158, USA
    J Orthop Res 30:919-26. 2012
    ....
  22. doi request reprint Visual grading of motion induced image degradation in high resolution peripheral computed tomography: impact of image quality on measures of bone density and micro-architecture
    J B Pialat
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA
    Bone 50:111-8. 2012
    ..These results provide estimates of the error in bone quality measures due to motion artifacts and provide an initial framework for developing standardized quality control criteria for cross-sectional and longitudinal HR-pQCT studies...
  23. pmc Mineral composition is altered by osteoblast expression of an engineered G(s)-coupled receptor
    G J Kazakia
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94107, USA
    Calcif Tissue Int 89:10-20. 2011
    ..Our findings suggest that bone tissue quality may be an important contributor to increased fracture risk in fibrous dysplasia patients...
  24. pmc Automated simulation of areal bone mineral density assessment in the distal radius from high-resolution peripheral quantitative computed tomography
    A J Burghardt
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, QB3 Building, Suite 203, 1700 4th St, San Francisco, CA 94158, USA
    Osteoporos Int 20:2017-24. 2009
    ..This technique represents a useful reference to gauge the utility of novel 3D quantification methods applied to HR-pQCT in multi-center clinical studies and potentially negates the need for separate forearm DXA measurements...
  25. ncbi request reprint The temporal changes of trabecular architecture in ovariectomized rats assessed by MicroCT
    A Laib
    Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco 94143-0686, USA
    Osteoporos Int 12:936-41. 2001
    ....
  26. pmc T1rho relaxation time of the meniscus and its relationship with T1rho of adjacent cartilage in knees with acute ACL injuries at 3 T
    R I Bolbos
    Musculo skeletal Quantitative Imaging Research MQIR, Department of Radiology, University of California, San Francisco UCSF, San Francisco, CA 94107, USA
    Osteoarthritis Cartilage 17:12-8. 2009
    ....
  27. ncbi request reprint Feasibility of in vivo structural analysis of high-resolution magnetic resonance images of the proximal femur
    Roland Krug
    MQIR, Department of Radiology, University of California, San Francisco, CA, USA
    Osteoporos Int 16:1307-14. 2005
    ..This feasibility study establishes the potential of MRI as a means of imaging proximal femur structure, and improvements in technique and resolution enhancements are warranted...
  28. pmc Assessment of bone tissue mineralization by conventional x-ray microcomputed tomography: comparison with synchrotron radiation microcomputed tomography and ash measurements
    G J Kazakia
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, California 94158, USA
    Med Phys 35:3170-9. 2008
    ..Our results indicate that muCT mineralization measures are underestimated but well-correlated with SRmuCT and gravimetric data, particularly when volume fraction groups are considered individually...
  29. ncbi request reprint Postmenopausal women treated with combination parathyroid hormone (1-84) and ibandronate demonstrate different microstructural changes at the radius vs. tibia: the PTH and Ibandronate Combination Study (PICS)
    A L Schafer
    Endocrine Research Unit, San Francisco Veterans Affairs Medical Center, 4150 Clement Street, 111N, San Francisco, CA, 94121, USA
    Osteoporos Int 24:2591-601. 2013
    ..Cortical and trabecular changes were different at the nonweight-bearing radius vs. the weight-bearing tibia, with more favorable overall changes at the tibia...
  30. ncbi request reprint Advances in imaging: impact on studying craniofacial bone structure
    S Majumdar
    Department of Radiology, University of California, San Francisco, CA 94143, USA
    Orthod Craniofac Res 6:48-51. 2003
    ..Examples of in vitro and in vivo images are presented...
  31. ncbi request reprint Quantification of articular cartilage in the knee with pulsed saturation transfer subtraction and fat-suppressed MR imaging: optimization and validation
    C G Peterfy
    Department of Radiology, University of California, San Francisco 94143 0628
    Radiology 192:485-91. 1994
    ....
  32. ncbi request reprint Fully balanced steady-state 3D-spin-echo (bSSSE) imaging at 3 Tesla
    R Krug
    Musculoskeletal and Quantitative Imaging Research, Department of Radiology, University of California San Francisco, San Francisco, California, USA
    Magn Reson Med 56:1033-40. 2006
    ..Comparisons of structural bone parameters revealed a difference of less than 3% for all structural parameters between parallel and conventional imaging...
  33. pmc Baseline mean and heterogeneity of MR cartilage T2 are associated with morphologic degeneration of cartilage, meniscus, and bone marrow over 3 years--data from the Osteoarthritis Initiative
    G B Joseph
    Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA
    Osteoarthritis Cartilage 20:727-35. 2012
    ....
  34. pmc Conditional expression of a Gi-coupled receptor in osteoblasts results in trabecular osteopenia
    J Peng
    Endocrine Research Unit, Veterans Affairs Medical Center, and Department of Medicine, University of California, San Francisco, California 94121, USA
    Endocrinology 149:1329-37. 2008
    ..The skeletal phenotype in Ro1 mice bears some similarity to that produced by knockout of Gs-alpha expression in osteoblasts and thus may be due at least in part to Gi-mediated inhibition of adenylyl cyclase...
  35. ncbi request reprint Quantitative magnetic resonance imaging of articular cartilage in osteoarthritis
    G Blumenkrantz
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, San Francisco, CA, USA
    Eur Cell Mater 13:76-86. 2007
    ..The cross-sectional and longitudinal studies using these imaging techniques show promise for cartilage assessment and for the study of osteoarthritis...
  36. pmc Quantification of trabecular bone structure using magnetic resonance imaging at 3 Tesla--calibration studies using microcomputed tomography as a standard of reference
    C A Sell
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, CA, USA
    Calcif Tissue Int 76:355-64. 2005
    ..These measures, although higher than the standard of reference, show a highly significant correlation with true structure measures obtained by microCT...
  37. ncbi request reprint The effects of synthetic conjugated estrogens, a (cenestin) on trabecular bone structure and strength in the ovariectomized rat model
    N E Lane
    Department of Medicine, University of California at San Francisco, San Francisco, CA 94143, USA
    Osteoporos Int 13:816-23. 2002
    ..In summary, Cenestin maintained trabecular bone microarchitecture and strength in an ovariectomized rat model of estrogen deficiency...
  38. pmc Cartilage and meniscus assessment using T1rho and T2 measurements in healthy subjects and patients with osteoarthritis
    Z A Zarins
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158, USA
    Osteoarthritis Cartilage 18:1408-16. 2010
    ..The purpose of this study was to evaluate meniscal degeneration in healthy subjects and subjects with osteoarthritis (OA) using T(1ρ) and T(2) measurements and to examine the interrelationship between cartilage and meniscus abnormalities...
  39. ncbi request reprint Magnetic resonance imaging measurement of relaxation and water diffusion in the human lumbar intervertebral disc under compression in vitro
    E J Chiu
    Department of Radiology, University of California, Berkeley San Francisco, California, USA
    Spine (Phila Pa 1976) 26:E437-44. 2001
    ..CONCLUSIONS: This study demonstrated that magnetic resonance imaging can be used to measure significant changes in T1, T2, or diffusion in intervertebral disc specimens by region, loading condition, or Thompson grade...
  40. doi request reprint A novel fast knee cartilage segmentation technique for T2 measurements at MR imaging--data from the Osteoarthritis Initiative
    C Stehling
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California San Francisco, 185 Berry Street, San Francisco, CA 94107, USA
    Osteoarthritis Cartilage 19:984-9. 2011
    ..59%) than for mean T(2) (1.57%) and laminar analysis (up to 2.17%). Due to these results, the novel DST can be recommended for T(2) measurements in large clinical trials like the OAI...
  41. ncbi request reprint Fourier Transform Infrared Imaging of focal lesions in human osteoarthritic cartilage
    E David-Vaudey
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, CA 94107, USA
    Eur Cell Mater 10:51-60; discussion 60. 2005
    ..This study has demonstrated that FTIRI is useful in quantitatively assessing pathology-related changes in the composition and distribution of primary macromolecular components of human osteoarthritic cartilage...
  42. ncbi request reprint Trabecular structure assessment in lumbar vertebrae specimens using quantitative magnetic resonance imaging and relationship with mechanical competence
    O Beuf
    Department of Radiology, University of California, San Francisco, 94143-1290, USA
    J Bone Miner Res 16:1511-9. 2001
    ..79 and 0.92). However, in the direction perpendicular to the magnetic field, T2' values enhanced the adjusted R2 correlation value with horizontal (M/L) stress values in addition to BMD from 0.70 to 0.91 (p < 0.05)...
  43. ncbi request reprint A review of magnetic resonance (MR) imaging of trabecular bone micro-architecture: contribution to the prediction of biomechanical properties and fracture prevalence
    S Majumdar
    Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco 94143, USA
    Technol Health Care 6:321-7. 1998
    ..MR derived measures are compared to measures of trabecular bone mineral density (BMD) in the hip using dual X-ray absorptiometry (DXA)...
  44. ncbi request reprint Magnetic resonance evaluation of the interrelationship between articular cartilage and trabecular bone of the osteoarthritic knee
    C T Lindsey
    Magnetic Resonance Science Center, University of California, CA, San Francisco, USA
    Osteoarthritis Cartilage 12:86-96. 2004
    ..To use high-resolution magnetic resonance imaging (MRI) to determine the relationship between articular cartilage degeneration and trabecular bone changes of the femur, condyles and tibia in human knees with osteoarthritis (OA)...
  45. ncbi request reprint Magnetic resonance imaging of iron oxide labelled stem cells: applications to tissue engineering based regeneration of the intervertebral disc
    K J Saldanha
    MQIR, Department of Radiology, University of California, San Francisco, CA, USA
    Eur Cell Mater 16:17-25. 2008
    ..Finally, labelling does not significantly impair cell viability. Consequently, this technique shows promise as a potential method for in vivo longitudinal tracking of stem cell based regeneration of the IVD...
  46. ncbi request reprint Technical factors in fractal analysis of periapical radiographs
    L Jolley
    Department of Growth and Development, University of California, San Francisco, USA
    Dentomaxillofac Radiol 35:393-7. 2006
    ..The use of non-standardized radiographic techniques potentially limits the reliability of fractal analysis. The objective of this study was to determine how variations in radiographic technique affect fractal dimension...
  47. doi request reprint The effects of acute loading on T1rho and T2 relaxation times of tibiofemoral articular cartilage
    R B Souza
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94107, USA
    Osteoarthritis Cartilage 18:1557-63. 2010
    ..To evaluate the effect of acute loading on healthy and osteoarthritic knee cartilage T(1ρ) and T(2) relaxation times...
  48. ncbi request reprint MR imaging and early cartilage degeneration and strategies for monitoring regeneration
    S Majumdar
    Musculoskeletal and Quantitative Imaging Research MQIR, University of California, San Francisco, CA 94158, USA
    J Musculoskelet Neuronal Interact 6:382-4. 2006
  49. ncbi request reprint Magnetic resonance imaging and spectroscopy of the intervertebral disc
    S Majumdar
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, CA 94158, USA
    NMR Biomed 19:894-903. 2006
    ..With the potential for gaining morphological and biochemical information, MRI shows promise for quantitative assessment of disc health...
  50. ncbi request reprint T2 relaxation time histograms in multiple sclerosis
    D Grenier
    Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco, California, USA
    Magn Reson Imaging 20:733-41. 2002
    ..The results of this study showed that the method is easy to implement and may be used to characterize MS pathology...
  51. ncbi request reprint Fuzzy logic structure analysis of trabecular bone of the calcaneus to estimate proximal femur fracture load and discriminate subjects with and without vertebral fractures using high-resolution magnetic resonance imaging at 1.5 T and 3 T
    Priyesh V Patel
    Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
    Calcif Tissue Int 81:294-304. 2007
    ..Local femoral measurements are still needed to estimate femoral bone strength. Overall, parameters obtained at 3.0 T performed better than those at 1.5 T...
  52. ncbi request reprint Automatic prospective registration of high-resolution trabecular bone images of the tibia
    Janet Blumenfeld
    Department of Radiology, University of California, 1700 4th St, Suite 203, Box 2520, San Francisco, CA 94107, USA
    Ann Biomed Eng 35:1924-31. 2007
    ..5% range which are within values previously reported in the literature. Results suggest that this algorithm is robust enough to be used in different musculoskeletal imaging applications including the hip as well as the tibia...
  53. ncbi request reprint Partially parallel MR spectroscopic imaging of gliomas at 3T
    Esin Ozturk
    UCSF UCB Joint Graduate Group in Bioengineering, University of California, San Francisco, CA, USA
    Conf Proc IEEE Eng Med Biol Soc 1:493-6. 2006
    ....
  54. pmc Technical evaluation of in vivo abdominal fat and IMCL quantification using MRI and MRSI at 3 T
    Xiaojuan Li
    Musculoskeletal Quantitative Imaging Research, Department of Radiology, University of California, San Francisco, CA 94107, USA
    Magn Reson Imaging 26:188-97. 2008
    ....
  55. doi request reprint Rapid in vivo musculoskeletal MR with parallel imaging at 7T
    Suchandrima Banerjee
    Radiology, University of California, San Francisco, San Francisco, California 94158, USA
    Magn Reson Med 59:655-60. 2008
    ..Robust quantification of bone and cartilage metrics could be derived from accelerated ankle and knee acquisitions. PI can enhance the clinical feasibility of in vivo bone and cartilage HR-MRI for osteoporosis and osteoarthritis at 7T...
  56. ncbi request reprint Fast magnetic resonance spectroscopic imaging at 3 Tesla using autocalibrating parallel technique
    Suchandrima Banerjee
    Joint Graduate Group in Bioeng, California Univ, Berkeley, San Francisco, CA, USA
    Conf Proc IEEE Eng Med Biol Soc 1:1866-9. 2006
    ..Employing two fold undersampling in two phase-encoding directions, a four fold reduction in scantime was simulated. Metabolic parameters showed close agreement between the full and GRAPPA reconstructed spectral data...
  57. doi request reprint Feasibility and reproducibility of relaxometry, morphometric, and geometrical measurements of the hip joint with magnetic resonance imaging at 3T
    Julio Carballido-Gamio
    Department of Radiology, University of California San Francisco, 1700 4th Street, San Francisco, CA 94158, USA
    J Magn Reson Imaging 28:227-35. 2008
    ..To test the feasibility of in vivo magnetic resonance T(1rho) relaxation time measurements of hip cartilage, and quantify the reproducibility of hip cartilage thickness, volume, T(2), T(1rho), and size of femoral head measurements...
  58. ncbi request reprint Partially-parallel, susceptibility-weighted MR imaging of brain vasculature at 7 Tesla using sensitivity encoding and an autocalibrating parallel technique
    Janine M Lupo
    University of California San Francisco, CA, USA
    Conf Proc IEEE Eng Med Biol Soc 1:747-50. 2006
    ....
  59. ncbi request reprint The effects of geometric and threshold definitions on cortical bone metrics assessed by in vivo high-resolution peripheral quantitative computed tomography
    Kevin A Davis
    Department of Mechanical Engineering, University of California Berkeley, Berkeley, CA, USA
    Calcif Tissue Int 81:364-71. 2007
    ..Furthermore, while the direct 3D Ct.Th method is less sensitive to threshold effects, both methods are moderate predictors of mechanical strength, with the annular method being the stronger correlate...
  60. pmc New techniques for cartilage magnetic resonance imaging relaxation time analysis: texture analysis of flattened cartilage and localized intra- and inter-subject comparisons
    Julio Carballido-Gamio
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, San Francisco, California 94158, USA
    Magn Reson Med 59:1472-7. 2008
    ..The results indicate that the presented techniques have potential in longitudinal and population studies of knee OA at different stages of the disease...
  61. doi request reprint Proximal femur specimens: automated 3D trabecular bone mineral density analysis at multidetector CT--correlation with biomechanical strength measurement
    Markus B Huber
    Musculoskeletal and Quantitative Imaging Research, Department of Radiology, University of California, San Francisco, 185 Berry St, Suite 350, San Francisco, CA 94107, USA
    Radiology 247:472-81. 2008
    ....
  62. doi request reprint In vivo ultra-high-field magnetic resonance imaging of trabecular bone microarchitecture at 7 T
    Roland Krug
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
    J Magn Reson Imaging 27:854-9. 2008
    ....
  63. pmc Randomized trial of once-weekly parathyroid hormone (1-84) on bone mineral density and remodeling
    Dennis M Black
    Department of Epidemiology and Biostatistics, University of California San Francisco, 185 Berry Street, San Francisco, CA 94107, USA
    J Clin Endocrinol Metab 93:2166-72. 2008
    ..Daily PTH administration increases bone mineral density (BMD) and reduces fracture risk. However, cost and compliance significantly limit clinical use...
  64. pmc Quantitative assessment of bone marrow edema-like lesion and overlying cartilage in knees with osteoarthritis and anterior cruciate ligament tear using MR imaging and spectroscopic imaging at 3 Tesla
    Xiaojuan Li
    Musculo skeletal Quantitative Imaging Research MQIR, Department of Radiology, University of California, San Francisco UCSF, San Francisco, California 94107, USA
    J Magn Reson Imaging 28:453-61. 2008
    ..To quantitatively assess bone marrow edema-like lesion (BMEL) and the overlying cartilage in osteoarthritis (OA) or anterior cruciate ligament (ACL)-injured knees using magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI)...
  65. doi request reprint Lactic acid and proteoglycans as metabolic markers for discogenic back pain
    Kayvan R Keshari
    Department of Radiology, University of California, San Francisco, CA 94158 2330, USA
    Spine (Phila Pa 1976) 33:312-7. 2008
    ..These samples were then analyzed using ex vivo proton high resolution magic angle spinning (HR-MAS) NMR spectroscopy to produce metabolic profiles for comparison between the 2 patient groups...
  66. pmc Quantitative assessment of bone tissue mineralization with polychromatic micro-computed tomography
    Andrew J Burghardt
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94158, USA
    Calcif Tissue Int 83:129-38. 2008
    ..80). In cortical bone specimens, the correlation was somewhat weaker when a global threshold was applied (R (2) = 0.67) compared to the local threshold method (R (2) = 0.78)...
  67. pmc Resolution dependence of the non-metric trabecular structure indices
    Miki Sode
    Joint Graduate Group in Bioengineering, University of California at San Francisco and Berkeley, San Francisco and Berkeley, CA, USA
    Bone 42:728-36. 2008
    ..g. relative resolution, the size of the treatment effect to detect, and specimen type). The results of this study provide an upper bound for the accuracy of the non-metric indices under limited resolution scenarios...
  68. pmc In vivo T(1rho) mapping in cartilage using 3D magnetization-prepared angle-modulated partitioned k-space spoiled gradient echo snapshots (3D MAPSS)
    Xiaojuan Li
    Musculoskeletal Quantitative Imaging Research, Department of Radiology, University of California San Francisco, 185 Berry Street, San Francisco, CA 94107, USA
    Magn Reson Med 59:298-307. 2008
    ..6%, with regional CV ranging from 1.7% to 8.7%. The fitting errors using MAPSS were significantly lower (P < 0.05) than those using sequences without RF cycling and variable flip angles...
  69. pmc Reproducibility of the quantitative assessment of cartilage morphology and trabecular bone structure with magnetic resonance imaging at 7 T
    Jin Zuo
    Department of Radiology, Musculoskeletal and Quantitative Imaging Research, University of California, Box 2520, San Francisco, CA 94158 2520, USA
    Magn Reson Imaging 26:560-6. 2008
    ....
  70. ncbi request reprint Magnetic resonance imaging for osteoporosis
    Sharmila Majumdar
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, QB3 Building, 2nd Floor, Suite 203 1700, 4th Street, Campus Box 2520, San Francisco, CA 94158, USA
    Skeletal Radiol 37:95-7. 2008
  71. ncbi request reprint Single-shot fast spin-echo diffusion tensor imaging of the lumbar spine at 1.5 and 3 T
    Julio Carballido-Gamio
    Department of Radiology, University of California San Francisco, CA 94158, USA
    Magn Reson Imaging 25:665-70. 2007
    ..Results indicate that DTI-SSFSE is a candidate as a clinical sequence for obtaining diffusion tensor images of the lumbar intervertebral discs with scan times shorter than 4 min...
  72. ncbi request reprint Analysis of trabecular bone structure with multidetector spiral computed tomography in a simulated soft-tissue environment
    Jan S Bauer
    Musculoskeletal and Quantitative Imaging Research, Department of Radiology, University of California in San Francisco, San Francisco, CA, USA
    Calcif Tissue Int 80:366-73. 2007
    ..Even though ST scatter compromises image quality substantially, the major characteristics of the trabecular network can still be appreciated and quantified...
  73. ncbi request reprint A three-dimensional MRI analysis of knee kinematics
    Vikas V Patel
    Department of Orthopaedic Surgery, University of California, San Francisco, CA 94143, USA
    J Orthop Res 22:283-92. 2004
    ....
  74. ncbi request reprint In vivo application of 3D-line skeleton graph analysis (LSGA) technique with high-resolution magnetic resonance imaging of trabecular bone structure
    Laurent Pothuaud
    Department of Radiology, Magnetic Resonance Science Center, University of California San Francisco, 1 Irving Street, Room AC 109, San Francisco, CA 94143 1290, USA
    Osteoporos Int 15:411-9. 2004
    ..However, this paper demonstrated the feasibility of using 3D-LSGA based evaluation coupled with in vivo high-resolution MR imaging as a complementary approach for the monitoring of trabecular bone changes in individual subjects...
  75. ncbi request reprint T2 relaxation time of cartilage at MR imaging: comparison with severity of knee osteoarthritis
    Timothy C Dunn
    Department of Radiology, University of California at San Francisco, 185 Berry St, Suite 350, San Francisco, CA 94107 1739, USA
    Radiology 232:592-8. 2004
    ....
  76. ncbi request reprint Diffraction enhanced imaging of articular cartilage and comparison with micro-computed tomography of the underlying bone structure
    Sharmila Majumdar
    Department of Radiology, University of California, San Francisco, CA 94143, USA
    Eur Radiol 14:1440-8. 2004
    ..These data reflect the ability of X-ray based emerging technologies to depict cartilage-bone interactions in joint degeneration...
  77. ncbi request reprint Trabecular bone structure of the distal radius, the calcaneus, and the spine: which site predicts fracture status of the spine best?
    Thomas M Link
    Department of Diagnostic Radiology, Technische Universitaet Muenchen, Munich, Germany
    Invest Radiol 39:487-97. 2004
    ....
  78. ncbi request reprint Contribution of inter-site variations in architecture to trabecular bone apparent yield strains
    Elise F Morgan
    Orthopaedic Biomechanics Laboratory, Department of Mechanical Engineering, University of California, Berkeley, CA 94720, USA
    J Biomech 37:1413-20. 2004
    ..These findings indicate the importance of incorporating large deformation capabilities in computational analyses of trabecular bone. This may be critical when investigating the biomechanical consequences of trabecular thinning and loss...
  79. ncbi request reprint Trabecular bone is more deteriorated in spinal cord injured versus estrogen-free postmenopausal women
    Jill M Slade
    Department of Exercise Science, University of Georgia, 300 River Road, Athens, GA 30602, USA
    Osteoporos Int 16:263-72. 2005
    ..We conclude that the effect of unloading on bone architecture is greater than that of estrogen loss in middle-aged women...
  80. ncbi request reprint Computer-aided quantification of focal cartilage lesions of osteoarthritic knee using MRI
    Keh Yang Lee
    Department of Radiology, University of California, San Francisco, San Francisco, California, USA
    Magn Reson Imaging 22:1105-15. 2004
    ....
  81. ncbi request reprint Trabecular bone microarchitecture is deteriorated in men with spinal cord injury
    Christopher M Modlesky
    Department of Health, Nutrition and Exercise Sciences, University of Delaware, Newark, Delaware 19716, USA
    J Bone Miner Res 19:48-55. 2004
    ..The deteriorated trabecular bone microarchitecture may contribute to the increased fracture incidence after injury...
  82. ncbi request reprint X-ray detection of structural orientation in human articular cartilage
    Carol Muehleman
    Department of Anatomy and Cell Biology, Rush Medical College, IL 60612, Chicago, USA
    Osteoarthritis Cartilage 12:97-105. 2004
    ..To determine the feasibility of detecting the structural orientation in cartilage with Diffraction Enhanced X-Ray Imaging...
  83. ncbi request reprint Combination of topological parameters and bone volume fraction better predicts the mechanical properties of trabecular bone
    Laurent Pothuaud
    Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco, CA 94143 1290, USA
    J Biomech 35:1091-9. 2002
    ..Such formulations could potentially be used to increase the prediction of the mechanical properties of trabecular bone...
  84. ncbi request reprint Insulin-like growth factor I is required for the anabolic actions of parathyroid hormone on mouse bone
    Daniel D Bikle
    Department of Medicine, Veterans Affairs Medical Center and University of California, San Francisco 94121, USA
    J Bone Miner Res 17:1570-8. 2002
    ..These results indicate that IGF-I is required for the anabolic actions of PTH on bone formation, but the defect lies distal to the initial response of the osteoblast to PTH...
  85. ncbi request reprint Three-dimensional-line skeleton graph analysis of high-resolution magnetic resonance images: a validation study from 34-microm-resolution microcomputed tomography
    Laurent Pothuaud
    Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco, 94143 1290, USA
    J Bone Miner Res 17:1883-95. 2002
    ..57-0.64 for morphological measurements. 3D-LSGA technique could be applied to in vivo high-resolution MRIs of trabecular bone structure, giving an indirect characterization of the microtrabecular bone network...
  86. ncbi request reprint Magnetic resonance imaging of trabecular bone structure
    Sharmila Majumdar
    Department of Radiology, Magnetic Resonance Science Center, University of California San Francisco, Box 1290, 1 Irving Street, San Francisco, CA 94143, USA
    Top Magn Reson Imaging 13:323-34. 2002
  87. ncbi request reprint MicroCT evaluation of normal and osteoarthritic bone structure in human knee specimens
    Vikas Patel
    Department of Orthopaedic Surgery, University of California, San Francisco, CA 94143 1290, USA
    J Orthop Res 21:6-13. 2003
    ..Severely arthritic bone changes are most prominent in the medial compartment of the tibia and bone structure is less sound in severe arthritis...
  88. ncbi request reprint Micro-computed tomography evaluation of trabecular bone structure on loaded mice tail vertebrae
    Ahi Sema Issever
    Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco 94143 1290, USA
    Spine (Phila Pa 1976) 28:123-8. 2003
    ..A micro-computed tomography (CT) study of the trabecular bone structure on loaded mice tail vertebral bodies was conducted...
  89. ncbi request reprint Magnetic resonance imaging of patellofemoral kinematics with weight-bearing
    Vikas V Patel
    Department of Orthopaedic Surgery, University of California, 400 Parnassus, ACC 3, San Francisco, CA 94117, USA
    J Bone Joint Surg Am 85:2419-24. 2003
    ..The present study was designed to define the relationship between the patellofemoral contact area and patellofemoral kinematics in vivo...
  90. ncbi request reprint Normalized cuts in 3-D for spinal MRI segmentation
    Julio Carballido-Gamio
    Joint Graduate Group in Bioengineering, University of California, San Francisco, 94143 1290, USA
    IEEE Trans Med Imaging 23:36-44. 2004
    ..Results of the segmentation as well as limitations and challenges in this area are presented...
  91. ncbi request reprint A study of the relationship between molecular biomarkers of joint degeneration and the magnetic resonance-measured characteristics of cartilage in 16 symptomatic knees
    Karen B King
    Department of Medicine, University of California at San Francisco, Richmond, CA 94804, USA
    Magn Reson Imaging 22:1117-23. 2004
    ..Our findings support the hypothesis that cartilage molecular biomarkers reflect the molecular processes of cartilage degeneration and loss...
  92. ncbi request reprint A pilot, two-year longitudinal study of the interrelationship between trabecular bone and articular cartilage in the osteoarthritic knee
    Gabrielle Blumenkrantz
    Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, CA 94107, USA
    Osteoarthritis Cartilage 12:997-1005. 2004
    ..To examine the relationship between structural changes of trabecular bone and cartilage, in patients with varying degrees of osteoarthritis (OA) over 2 years, using magnetic resonance imaging...
  93. ncbi request reprint Evaluation of fetal bone structure and mineralization in IGF-I deficient mice using synchrotron radiation microtomography and Fourier transform infrared spectroscopy
    Andrew J Burghardt
    Musculoskeletal Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, QB3 Byers Hall, Suite 203, 1700 4th Street, San Francisco, CA 94158, USA
    Bone 40:160-8. 2007
    ..The advantages unique to SR-microCT allow for 3D visualization and quantification of pre-natal bone microstructure and mineral density in mice which was not previously possible...
  94. ncbi request reprint A feasibility study of in vivo T1rho imaging of the intervertebral disc
    Gabrielle Blumenkrantz
    Department of Radiology, University of California San Francisco, QB3 Building, Box 2520, San Francisco, CA 94158, USA
    Magn Reson Imaging 24:1001-7. 2006
    ..The purpose of this study was to test the feasibility of quantifying T1rho relaxation time in phantoms and intervertebral discs of healthy volunteers using in vivo MR imaging at 3 T...
  95. ncbi request reprint Characterization of trabecular bone structure from high-resolution magnetic resonance images using fuzzy logic
    Julio Carballido-Gamio
    MQIR, Department of Radiology, University of California, San Francisco, San Francisco, CA 94158, USA
    Magn Reson Imaging 24:1023-9. 2006
    ..85; P<.001) and good agreements based on Bland-Altman analysis, suggesting that the level of fuzziness in high-resolution magnetic resonance images could be related to the trabecular bone structure...
  96. ncbi request reprint New imaging technologies in the diagnosis of osteoporosis
    Galateia J Kazakia
    Musculoskeletal and Quantitative Imaging Research Group, UCSF Department of Radiology, 1700 4th Street, Suite 203, San Francisco, CA 94143, USA
    Rev Endocr Metab Disord 7:67-74. 2006
    ..The performance of these techniques in predicting osteoporotic fracture and assessing strength indices are discussed...
  97. ncbi request reprint Volumetric cartilage measurements of porcine knee at 1.5-T and 3.0-T MR imaging: evaluation of precision and accuracy
    Jan S Bauer
    Musculoskeletal and Quantitative Imaging Research, Department of Radiology, University of California, San Francisco, Calif, USA
    Radiology 241:399-406. 2006
    ..To compare the precision and accuracy of 3.0-T and 1.5-T magnetic resonance (MR) imaging in the quantification of cartilage volume by using direct volumetric measurements as a reference standard...
  98. ncbi request reprint Wavelet-based characterization of vertebral trabecular bone structure from magnetic resonance images at 3 T compared with micro-computed tomographic measurements
    Roland Krug
    MQIR, Department of Radiology, University of California, San Francisco, CA 94143 2520, USA
    Magn Reson Imaging 25:392-8. 2007
    ....
  99. ncbi request reprint Insulin-like growth factor I stimulates recovery of bone lost after a period of skeletal unloading
    Benjamin M Boudignon
    Division of Endocrinology, Veterans Affairs Medical Center, and Department of Medicine, University of California, San Francisco, California, USA
    J Appl Physiol (1985) 103:125-31. 2007
    ....
  100. ncbi request reprint Volumetric quantitative CT of the spine and hip derived from contrast-enhanced MDCT: conversion factors
    Jan S Bauer
    Department of Radiology, Technische Univerität München, Klinikum rechts der Isar, Institut für Roentgendiagnostik, Ismaninger Str 22, Munchen, Germany 81675
    AJR Am J Roentgenol 188:1294-301. 2007
    ....
  101. ncbi request reprint Clinical utility of microarchitecture measurements of trabecular bone
    Julio Carballido-Gamio
    QB3 Building, 2nd Floor, Suite 203, 1700 4th Street, University of California, San Francisco, 94158, USA
    Curr Osteoporos Rep 4:64-70. 2006
    ..Results demonstrating the ability to distinguish between different populations based on trabecular bone microarchitecture in longitudinal studies are also presented for the various imaging modalities...