Susan M Majka

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. pmc Evidence for cell fusion is absent in vascular lesions associated with pulmonary arterial hypertension
    S M Majka
    Cardiovascular Pulmonary Research, University of Colorado Denver, Aurora, Colorado 80045, USA
    Am J Physiol Lung Cell Mol Physiol 295:L1028-39. 2008
  2. ncbi request reprint Identification of novel resident pulmonary stem cells: form and function of the lung side population
    Susan M Majka
    Department of Medicine, Cardiovascular Pulmonary Research Section, University of Colorado Health Sciences Center, 4200 East 9th Avenue, SOM 3811, mail stop B 133, Denver, Colorado 80262, USA
    Stem Cells 23:1073-81. 2005
  3. ncbi request reprint Pleiotropic role of VEGF-A in regulating fetal pulmonary mesenchymal cell turnover
    S Majka
    Department of Medicine, Cardiovascular Pulmonary Research Section, University of Colorado Health Sciences Center, 4200 E 9th Ave, Denver, CO 80262, USA
    Am J Physiol Lung Cell Mol Physiol 290:L1183-92. 2006
  4. pmc De novo generation of white adipocytes from the myeloid lineage via mesenchymal intermediates is age, adipose depot, and gender specific
    Susan M Majka
    Charles C Gates Regenerative Medicine and Stem Cell Biology Program, Department of Pediatrics, Cardiovascular Pulmonary Research Laboratory, University of Colorado, Aurora, CO 80045, USA
    Proc Natl Acad Sci U S A 107:14781-6. 2010
  5. pmc Reduction of reactive oxygen species prevents hypoxia-induced CREB depletion in pulmonary artery smooth muscle cells
    Dwight J Klemm
    Cardiovascular Pulmonary Research Laboratory, University of Colorado Denver, Aurora, CO 80045, USA
    J Cardiovasc Pharmacol 58:181-91. 2011
  6. pmc Attenuated Pik3r1 expression prevents insulin resistance and adipose tissue macrophage accumulation in diet-induced obese mice
    Carrie E McCurdy
    Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA
    Diabetes 61:2495-505. 2012
  7. pmc Concise review: adipocyte origins: weighing the possibilities
    Susan M Majka
    Gates Center for Stem Cell Biology and Regenerative Medicine, University of Colorado Denver, Aurora, Colorado 80045, USA
    Stem Cells 29:1034-40. 2011
  8. pmc Osteoblasts derived from induced pluripotent stem cells form calcified structures in scaffolds both in vitro and in vivo
    Ganna Bilousova
    Charles C Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado Denver, Aurora, Colorado 80045, USA
    Stem Cells 29:206-16. 2011
  9. pmc Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells
    Joseph T Crossno
    Research Section, Veterans Affairs Medical Center, Denver, CO, USA
    J Clin Invest 116:3220-8. 2006
  10. ncbi request reprint Mice deficient in galectin-1 exhibit attenuated physiological responses to chronic hypoxia-induced pulmonary hypertension
    D Case
    Cardiovascular Pulmonary Research Laboratory, Division of Cardiology and Department of Medicine, University of Colorado Health Science Center, 4200 E 9th Avenue, Denver, CO 80262, USA
    Am J Physiol Lung Cell Mol Physiol 292:L154-64. 2007

Collaborators

Detail Information

Publications16

  1. pmc Evidence for cell fusion is absent in vascular lesions associated with pulmonary arterial hypertension
    S M Majka
    Cardiovascular Pulmonary Research, University of Colorado Denver, Aurora, Colorado 80045, USA
    Am J Physiol Lung Cell Mol Physiol 295:L1028-39. 2008
    ..We found no evidence of increased ploidy to suggest cell fusion. Taken together, these data suggest that abnormal lesion formation in PAH occurs in the absence of cell fusion...
  2. ncbi request reprint Identification of novel resident pulmonary stem cells: form and function of the lung side population
    Susan M Majka
    Department of Medicine, Cardiovascular Pulmonary Research Section, University of Colorado Health Sciences Center, 4200 East 9th Avenue, SOM 3811, mail stop B 133, Denver, Colorado 80262, USA
    Stem Cells 23:1073-81. 2005
    ..The identification of this target population will potentially allow earlier treatment and, long term, a functional restoration of injured pulmonary tissue and lung health...
  3. ncbi request reprint Pleiotropic role of VEGF-A in regulating fetal pulmonary mesenchymal cell turnover
    S Majka
    Department of Medicine, Cardiovascular Pulmonary Research Section, University of Colorado Health Sciences Center, 4200 E 9th Ave, Denver, CO 80262, USA
    Am J Physiol Lung Cell Mol Physiol 290:L1183-92. 2006
    ....
  4. pmc De novo generation of white adipocytes from the myeloid lineage via mesenchymal intermediates is age, adipose depot, and gender specific
    Susan M Majka
    Charles C Gates Regenerative Medicine and Stem Cell Biology Program, Department of Pediatrics, Cardiovascular Pulmonary Research Laboratory, University of Colorado, Aurora, CO 80045, USA
    Proc Natl Acad Sci U S A 107:14781-6. 2010
    ..BMP-derived adipocytes may, therefore, account in part for adipose depot heterogeneity and detrimental changes in adipose metabolism and inflammation with aging and adiposity...
  5. pmc Reduction of reactive oxygen species prevents hypoxia-induced CREB depletion in pulmonary artery smooth muscle cells
    Dwight J Klemm
    Cardiovascular Pulmonary Research Laboratory, University of Colorado Denver, Aurora, CO 80045, USA
    J Cardiovasc Pharmacol 58:181-91. 2011
    ..The data indicate that CREB levels in the arterial wall are regulated in part by oxidants produced in response to hypoxia and that CREB plays a crucial role in regulating SMC phenotype and PA remodeling...
  6. pmc Attenuated Pik3r1 expression prevents insulin resistance and adipose tissue macrophage accumulation in diet-induced obese mice
    Carrie E McCurdy
    Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA
    Diabetes 61:2495-505. 2012
    ....
  7. pmc Concise review: adipocyte origins: weighing the possibilities
    Susan M Majka
    Gates Center for Stem Cell Biology and Regenerative Medicine, University of Colorado Denver, Aurora, Colorado 80045, USA
    Stem Cells 29:1034-40. 2011
    ..This review will examine each of these process and their relevance to normal adipose tissue formation and contribution to obesity-related diseases...
  8. pmc Osteoblasts derived from induced pluripotent stem cells form calcified structures in scaffolds both in vitro and in vivo
    Ganna Bilousova
    Charles C Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado Denver, Aurora, Colorado 80045, USA
    Stem Cells 29:206-16. 2011
    ....
  9. pmc Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells
    Joseph T Crossno
    Research Section, Veterans Affairs Medical Center, Denver, CO, USA
    J Clin Invest 116:3220-8. 2006
    ..We conclude that TZDs and high-fat feeding promote the trafficking of BM-derived circulating progenitor cells to adipose tissue and their differentiation into ML adipocytes...
  10. ncbi request reprint Mice deficient in galectin-1 exhibit attenuated physiological responses to chronic hypoxia-induced pulmonary hypertension
    D Case
    Cardiovascular Pulmonary Research Laboratory, Division of Cardiology and Department of Medicine, University of Colorado Health Science Center, 4200 E 9th Avenue, Denver, CO 80262, USA
    Am J Physiol Lung Cell Mol Physiol 292:L154-64. 2007
    ..These results suggest that Gal-1 influences the contractile response to hypoxia and subsequent remodeling during hypoxia-induced PH, which influences disease progression...
  11. ncbi request reprint Depletion of cAMP-response element-binding protein/ATF1 inhibits adipogenic conversion of 3T3-L1 cells ectopically expressing CCAAT/enhancer-binding protein (C/EBP) alpha, C/EBP beta, or PPAR gamma 2
    Keith E Fox
    Research Service, Veterans Affairs Medical Center, University of Colorado Health Sciences Center, Denver, Colorado 80220, USA
    J Biol Chem 281:40341-53. 2006
    ..The data also indicate that CREB not only functions during the initiation of adipogenic conversion but also at later stages...
  12. doi request reprint Adult lung side population cells have mesenchymal stem cell potential
    J Martin
    Division of Cardiology, Cardiovascular Pulmonary Laboratory, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Cytotherapy 10:140-51. 2008
    ..METHODS We carried these observations forward by analyzing the MSC potential of single-cell clones, as well as their chromosomal stability and telomerase activity...
  13. ncbi request reprint Neonatal lung side population cells demonstrate endothelial potential and are altered in response to hyperoxia-induced lung simplification
    D Irwin
    Department of Medicine, Cardiovascular Pulmonary Research Section, University of Colorado Health Sciences Center, Denver, USA
    Am J Physiol Lung Cell Mol Physiol 293:L941-51. 2007
    ..The hyperoxia-induced changes in lung SP cells may limit their ability to effectively contribute to tissue morphogenesis during room air recovery...
  14. ncbi request reprint Altered phenotype and reduced function of muscle-derived hematopoietic stem cells
    Shannon L McKinney-Freeman
    Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Tex 77030, USA
    Exp Hematol 31:806-14. 2003
    ..Here we sought to clarify contradictions in the literature regarding the phenotype of ms-HSC and precisely define the hematopoietic origin of these cells...
  15. pmc Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration
    Susan M Majka
    Department of Pediatrics, Children s Nutrition Research Center, Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas 77030, USA
    J Clin Invest 111:71-9. 2003
    ..Thus, distinct populations of vascular progenitors are resident within skeletal muscle, are derived from bone marrow, and exhibit different cell fates during injury-induced vascular regeneration...
  16. ncbi request reprint Stem cells: a minireview
    Kathyjo A Jackson
    Center for Cell and Gene Therapy and Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA
    J Cell Biochem Suppl 38:1-6. 2002
    ..Caution is urged when interpreting these types of experiments because although they are stimulating, limitations of the technologies may provide misleading results...