Louis J Magnotti

Summary

Affiliation: University of Tennessee
Country: USA

Publications

  1. doi request reprint Admission ionized calcium levels predict the need for multiple transfusions: a prospective study of 591 critically ill trauma patients
    Louis J Magnotti
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 70:391-5; discussion 395-7. 2011
  2. doi request reprint Improved survival after hemostatic resuscitation: does the emperor have no clothes?
    Louis J Magnotti
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 70:97-102. 2011
  3. doi request reprint Causative pathogen dictates optimal duration of antimicrobial therapy for ventilator-associated pneumonia in trauma patients
    Louis J Magnotti
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Am Coll Surg 212:476-84; discussion 484-6. 2011
  4. doi request reprint Impact of gender on outcomes after blunt injury: a definitive analysis of more than 36,000 trauma patients
    Louis J Magnotti
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Am Coll Surg 206:984-91; discussion 991-2. 2008
  5. ncbi request reprint Reduction in inadequate empiric antibiotic therapy for ventilator-associated pneumonia: impact of a unit-specific treatment pathway
    Louis J Magnotti
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Am Surg 74:516-22; discussion 522-3. 2008
  6. doi request reprint Efficacy of monotherapy in the treatment of Pseudomonas ventilator-associated pneumonia in patients with trauma
    Louis J Magnotti
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 66:1052-8; discussion 1058-9. 2009
  7. doi request reprint Accounting for differences in transfusion volume: Are all massive transfusions created equal?
    John P Sharpe
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Trauma Acute Care Surg 72:1536-40. 2012
  8. ncbi request reprint A reappraisal of nitrogen requirements for patients with critical illness and trauma
    Roland N Dickerson
    Department of Clinical Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma Acute Care Surg 73:549-57. 2012
  9. doi request reprint Traumatic brain injury and β-blockers: not all drugs are created equal
    Thomas J Schroeppel
    From the University of Tennessee Health Science Center and Department of Pharmacy, Regional Medical Center at Memphis, Memphis, Tennessee
    J Trauma Acute Care Surg 76:504-9; discussion 509. 2014
  10. ncbi request reprint Applicability of an established management algorithm for destructive colon injuries after abbreviated laparotomy: a 17-year experience
    John P Sharpe
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN
    J Am Coll Surg 218:636-41. 2014

Collaborators

Detail Information

Publications70

  1. doi request reprint Admission ionized calcium levels predict the need for multiple transfusions: a prospective study of 591 critically ill trauma patients
    Louis J Magnotti
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 70:391-5; discussion 395-7. 2011
    ..We hypothesized that admission iCa levels could potentially predict the need for multiple transfusions in critically ill trauma patients...
  2. doi request reprint Improved survival after hemostatic resuscitation: does the emperor have no clothes?
    Louis J Magnotti
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 70:97-102. 2011
    ..To help resolve this controversy, we evaluated the temporal relationship between blood product administration and mortality in civilian trauma patients receiving MT...
  3. doi request reprint Causative pathogen dictates optimal duration of antimicrobial therapy for ventilator-associated pneumonia in trauma patients
    Louis J Magnotti
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Am Coll Surg 212:476-84; discussion 484-6. 2011
    ..The purpose of this study was to determine the appropriate duration of antimicrobial therapy for VAP in trauma patients secondary to hospital-acquired pathogens...
  4. doi request reprint Impact of gender on outcomes after blunt injury: a definitive analysis of more than 36,000 trauma patients
    Louis J Magnotti
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Am Coll Surg 206:984-91; discussion 991-2. 2008
    ..In an attempt to resolve this ongoing dispute, we evaluated the effect of gender on various outcomes in the largest single institutional series of trauma patients reported in the literature after blunt injury...
  5. ncbi request reprint Reduction in inadequate empiric antibiotic therapy for ventilator-associated pneumonia: impact of a unit-specific treatment pathway
    Louis J Magnotti
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Am Surg 74:516-22; discussion 522-3. 2008
    ..Adherence to a unit-specific pathway for the empiric management of VAP reduces multiple IEAT episodes. By limiting IEAT episodes, resource utilization and hospital mortality are significantly decreased...
  6. doi request reprint Efficacy of monotherapy in the treatment of Pseudomonas ventilator-associated pneumonia in patients with trauma
    Louis J Magnotti
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 66:1052-8; discussion 1058-9. 2009
    ..The relevance of such "synergy" is commonly supposed but poorly supported. The purpose of this study was to evaluate the efficacy of monotherapy in the treatment of Pseudomonas VAP as measured by microbiological resolution...
  7. doi request reprint Accounting for differences in transfusion volume: Are all massive transfusions created equal?
    John P Sharpe
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Trauma Acute Care Surg 72:1536-40. 2012
    ..We sought to evaluate the effect of the number of RBC units transfused on both plasma:RBC and platelet:RBC and their association with mortality in MT patients...
  8. ncbi request reprint A reappraisal of nitrogen requirements for patients with critical illness and trauma
    Roland N Dickerson
    Department of Clinical Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma Acute Care Surg 73:549-57. 2012
    ....
  9. doi request reprint Traumatic brain injury and β-blockers: not all drugs are created equal
    Thomas J Schroeppel
    From the University of Tennessee Health Science Center and Department of Pharmacy, Regional Medical Center at Memphis, Memphis, Tennessee
    J Trauma Acute Care Surg 76:504-9; discussion 509. 2014
    ..Dysautonomia in traumatic brain injury patients may contribute to secondary injury. We hypothesize that propranolol is the best β-blocker (BB) to block the excess catecholamines and improve mortality in this patient population...
  10. ncbi request reprint Applicability of an established management algorithm for destructive colon injuries after abbreviated laparotomy: a 17-year experience
    John P Sharpe
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN
    J Am Coll Surg 218:636-41. 2014
    ..The purpose of this study was to evaluate the applicability of this algorithm to destructive colon injuries after abbreviated laparotomy (AL) and to determine whether additional risk factors should be considered...
  11. doi request reprint Beta-adrenergic blockade and traumatic brain injury: protective?
    Thomas J Schroeppel
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Trauma 69:776-82. 2010
    ..We hypothesize that suppression of the catecholamine surge in multiple-injured TBI patients with beta-adrenergic blockade decreases mortality...
  12. doi request reprint Identifying life-threatening shock in the older injured patient: an analysis of the National Trauma Data Bank
    Ben L Zarzaur
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 68:1134-8. 2010
    ..We hypothesized that age x SI would be a better predictor of 48-hour mortality in old patients (age, >55 years) compared with TVS, whereas for young patients (age, <or=55 years), SI would be a better predictor than TVS...
  13. ncbi request reprint Initial chest CT obviates the need for repeat chest radiograph after penetrating thoracic trauma
    Louis J Magnotti
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Am Surg 73:569-72; discussion 572-3. 2007
    ....
  14. doi request reprint A ten-year review of enterocutaneous fistulas after laparotomy for trauma
    Peter E Fischer
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 67:924-8. 2009
    ..This study is the largest series of ECFs reported exclusively caused by trauma and examines the characteristics unique to this population...
  15. pmc The deleterious effect of red blood cell storage on microvascular response to transfusion
    Jordan A Weinberg
    From the Department of Surgery J A W, L J M, J M A, C A G, L E H, M A C, T C F, University of Tennessee Health Science Center, Memphis, Tennessee Department of Surgery P A M, M J V, J D K, L W R, University of Alabama at Birmingham, Birmingham, Alabama S R B is from the Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama Department of Pathology R P P, University of Alabama at Birmingham, Birmingham, Alabama
    J Trauma Acute Care Surg 75:807-12. 2013
    ..To assess this hypothesis, we evaluated microvascular perfusion in trauma patients during RBC transfusion...
  16. doi request reprint Toward a better definition of massive transfusion: focus on the interval of hemorrhage control
    John P Sharpe
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Trauma Acute Care Surg 73:1553-7. 2012
    ..In this study, we evaluated whether patients who reach the MT threshold during hemorrhage control differ clinically from those who reach it after hemorrhage control (i.e., after intensive care unit [ICU] arrival) but before 24 hours...
  17. doi request reprint Impact of airbags on a Level I trauma center: injury patterns, infectious morbidity, and hospital costs
    Regan F Williams
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Am Coll Surg 206:962-8; discussion 968-9. 2008
    ..We hypothesized that airbag use would be related to decreased injury severity of motor vehicle collision survivors admitted to a Level I trauma center, leading to a decrease in infectious morbidity and hospital resource use...
  18. ncbi request reprint Temporary abdominal closure techniques: a prospective randomized trial comparing polyglactin 910 mesh and vacuum-assisted closure
    Tiffany K Bee
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 65:337-42; discussion 342-4. 2008
    ..Some advocate polyglactin mesh (MESH), while others favor vacuum-assisted closure (VAC). We performed a single institution prospective randomized trial comparing morbidity and mortality differences between MESH and VAC...
  19. doi request reprint Antibiotic-coated ePTFE decreases graft colonization and neointimal hyperplasia
    Peter E Fischer
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Surg Res 156:199-204. 2009
    ..Thus, we hypothesized that the coated grafts would resist infection and have decreased neointimal hyperplasia when used in vivo in a large animal model...
  20. ncbi request reprint Angiographic embolization for liver injuries: low mortality, high morbidity
    Alicia M Mohr
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medcial School, Newark, 07103, USA
    J Trauma 55:1077-81; discussion 1081-2. 2003
    ..This study examines further the role of AE in both blunt and penetrating liver injuries and the outcomes of its use...
  21. doi request reprint Does plasma transfusion portend pulmonary dysfunction? A tale of two ratios
    John P Sharpe
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Trauma Acute Care Surg 75:32-6; discussion 36. 2013
    ..The purpose of this study was to evaluate the impact of plasma/PRBC on PaO2-to-FIO2 (P/F) ratio in the setting of massive transfusion (MT)...
  22. doi request reprint Functional outcomes following blunt cerebrovascular injury
    Jennifer M DiCocco
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Trauma Acute Care Surg 74:955-60. 2013
    ..This study was conducted to address those long-term outcomes...
  23. doi request reprint Use of the clinical pulmonary infection score to guide therapy for ventilator-associated pneumonia risks antibiotic overexposure in patients with trauma
    Nancy A Parks
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, USA
    J Trauma Acute Care Surg 73:52-8; discussion 58-9. 2012
    ..This study evaluates the use of CPIS in determining the appropriate duration of antimicrobial therapy for VAP in patients with critical illness and trauma...
  24. doi request reprint Adherence to a simplified management algorithm reduces morbidity and mortality after penetrating colon injuries: a 15-year experience
    John P Sharpe
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, USA
    J Am Coll Surg 214:591-7; discussion 597-8. 2012
    ..The purpose of this study was to evaluate the validity of this algorithm in the face of an increased incidence of destructive injuries observed in recent years...
  25. doi request reprint The "July phenomenon": is trauma the exception?
    Thomas J Schroeppel
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Am Coll Surg 209:378-84. 2009
    ..The objective of this study was to determine if a July phenomenon existed in a Level I trauma center with an attending present at all times...
  26. doi request reprint Impact of intracranial pressure monitor prophylaxis on central nervous system infections and bacterial multi-drug resistance
    Nathaniel F Stoikes
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Surg Infect (Larchmt) 9:503-8. 2008
    ..We tested the hypothesis that prophylactic antibiotics do not reduce the incidence of central nervous system (CNS) infections but instead are associated with the acquisition of multi-drug resistant (MDR) bacterial infections...
  27. ncbi request reprint The futility of the clinical pulmonary infection score in trauma patients
    Martin A Croce
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 60:523-7; discussion 527-8. 2006
    ..In this study, we evaluated the potential use of CPIS as the sole means for diagnosis of VAP in critically injured patients...
  28. doi request reprint Diagnostic laparoscopy for the evaluation of occult diaphragmatic injury following penetrating thoracoabdominal trauma
    Benjamin S Powell
    Department of Surgery, University of Tennessee Health Science Centre, Memphis, Tennessee
    Injury 39:530-4. 2008
    ....
  29. doi request reprint Necessity of repeat head CT and ICU monitoring in patients with minimal brain injury
    Tiffany K Bee
    Critical Care Trauma Division, Department of General Surgery, University of Tennessee, Memphis, Tennessee 38163, USA
    J Trauma 66:1015-8. 2009
    ..In an attempt to better allocate scarce resources, we hypothesized that not only was repeat head CT unnecessary but also routine intensive care unit (ICU) monitoring of these patients with MBI and stable examinations were unnecessary...
  30. ncbi request reprint Is ventilator-associated pneumonia in trauma patients an epiphenomenon or a cause of death?
    Louis J Magnotti
    Department of Surgery, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
    Surg Infect (Larchmt) 5:237-42. 2004
    ..We studied patients with less severe injuries (Injury Severity Score, ISS < 25) to determine the impact of VAP on outcomes...
  31. doi request reprint Impact of location on outcome after penetrating colon injuries
    John P Sharpe
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Trauma Acute Care Surg 73:1428-32; discussion 1433. 2012
    ..diversion) are based on a defined management algorithm regardless of injury location. The purpose of this study was to evaluate the effect of injury location on outcomes after penetrating colon injuries...
  32. doi request reprint Long-term survival and return on investment after nonneurologic injury: implications for the elderly trauma patient
    Ben L Zarzaur
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 69:93-8. 2010
    ..The purpose of this study was to evaluate the cost per 2-year survivor stratified by age after moderate- to severe-nonneurologic injury...
  33. doi request reprint Changes in pulmonary cytokines during antibiotic therapy for ventilator-associated pneumonia
    Joseph M Swanson
    Department of Clinical Pharmacy, University of Tennessee, Memphis, Tennessee 38163, USA
    Surg Infect (Larchmt) 11:161-7. 2010
    ..A major unanswered question in ventilator-associated pneumonia (VAP) management relates to patient response to therapy. We investigated the use of pulmonary cytokines as biomarkers for response to antibiotic therapy for VAP...
  34. doi request reprint Applicability of an established management algorithm for colon injuries following blunt trauma
    John P Sharpe
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma Acute Care Surg 74:419-24; discussion 424-5. 2013
    ..The purpose of this study was to evaluate the applicability of the ALG to blunt colon injuries...
  35. doi request reprint Impact of a defined management algorithm on outcome after traumatic pancreatic injury
    John P Sharpe
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Trauma Acute Care Surg 72:100-5. 2012
    ..Consequently, a management algorithm (ALG) was developed and implemented. The purpose of this study was to evaluate the impact of this ALG on outcomes...
  36. doi request reprint Components separation for abdominal wall reconstruction: the Memphis modification
    Jennifer M DiCocco
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Surgery 151:118-25. 2012
    ..The purpose of this manuscript is to describe in detail how to perform a modification of the components separation technique that has been shown to have one of the lowest recurrence rates in the literature...
  37. pmc Quality of life after abdominal wall reconstruction following open abdomen
    Ben L Zarzaur
    Department of Surgery and School of Nursing, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 70:285-91. 2011
    ..Results after DAWR demonstrate acceptable recurrence, morbidity, and mortality rates. However, little is known about quality of life (QOL) after DAWR. The purpose of this study was to analyze QOL after DAWR...
  38. doi request reprint The real risk of splenectomy after discharge home following nonoperative management of blunt splenic injury
    Ben L Zarzaur
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 66:1531-6; discussion 1536-8. 2009
    ..The purpose of this study was to analyze, using population-based data, the 180-day risk of splenectomy in a clinically relevant sample...
  39. ncbi request reprint "Awake" laparoscopy for the evaluation of equivocal penetrating abdominal wounds
    Jordan A Weinberg
    Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Injury 38:60-4. 2007
    ..We hypothesised that, in appropriate patients, diagnostic "awake" laparoscopy (AL) could be performed under local anaesthesia in the emergency department (ED), allowing for expedited discharge and potential cost savings...
  40. ncbi request reprint Penetrating rectal trauma: management by anatomic distinction improves outcome
    Jordan A Weinberg
    University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 60:508-13; discussion 513-14. 2006
    ..A clinical pathway was developed and implemented. Patients managed by the pathway (PATH) were compared with the previous study (PREV, n=58) to determine the impact of the clinical pathway on outcome...
  41. ncbi request reprint Injury location dictates utility of digital rectal examination and rigid sigmoidoscopy in the evaluation of penetrating rectal trauma
    M Brinson Hargraves
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Am Surg 75:1069-72. 2009
    ..RS proved better than DRE for diagnosis. The greatest benefit was observed with EP injuries. The possibility of a missed IP injury associated with a negative screen should prompt exploration if clinical suspicion is high...
  42. doi request reprint Comparison of intravenous ethanol versus diazepam for alcohol withdrawal prophylaxis in the trauma ICU: results of a randomized trial
    Jordan A Weinberg
    Section of Trauma, Burns, and Surgical Critical Care, Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Trauma 64:99-104. 2008
    ..The purpose of this study was to prospectively evaluate the efficacy of intravenous ethanol compared with benzodiazepines for the prevention of AWS with particular emphasis on the sedative effects of each therapy...
  43. pmc A population-based analysis of neighborhood socioeconomic status and injury admission rates and in-hospital mortality
    Ben L Zarzaur
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Am Coll Surg 211:216-23. 2010
    ..We hypothesized that injury-related hospitalization rates would vary by N-SES and that N-SES would be related to in-hospital mortality...
  44. doi request reprint New vitals after injury: shock index for the young and age x shock index for the old
    Ben L Zarzaur
    Department of Surgery at The University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Surg Res 147:229-36. 2008
    ..Because age negatively impacts physiological reserve, we hypothesized that age multiplied by SI (Age x SI) would be a better predictor of 48 h mortality (48 MORT) compared to heart rate (HR), systolic blood pressure (SBP), or SI...
  45. doi request reprint Methicillin-resistant Staphylococcus aureus in early ventilator-associated pneumonia: cause for concern?
    David M Hill
    1 Department of Pharmacy, The Regional Medical Center, Memphis, Tennessee
    Surg Infect (Larchmt) 14:520-4. 2013
    ..The rise in methicillin resistance within the community has led to a national increase in methicillin-resistant Staphylococcus aureus (MRSA) rates in early VAP and associated healthcare expenditure...
  46. pmc Outcomes of operations performed by attending surgeons after overnight trauma shifts
    John P Sharpe
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, USA
    J Am Coll Surg 216:791-7; discussion 797-9. 2013
    ..The purpose of this study was to investigate the impact of working an overnight trauma shift on outcomes of general surgery operations performed the next day by the post-call attending physician...
  47. ncbi request reprint Current issues in trauma
    Timothy C Fabian
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Curr Probl Surg 39:1160-244. 2002
  48. ncbi request reprint Emergent pelvic fixation in patients with exsanguinating pelvic fractures
    Martin A Croce
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Am Coll Surg 204:935-9; discussion 940-2. 2007
    ..Little published information is available about its effectiveness. This study evaluated the efficacy of the POD compared with EPF in patients with life-threatening pelvic fractures...
  49. doi request reprint Long-term follow-up of abdominal wall reconstruction after planned ventral hernia: a 15-year experience
    Jennifer M DiCocco
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38162, USA
    J Am Coll Surg 210:686-95, 695-8. 2010
    ....
  50. ncbi request reprint Minor trauma is an unrecognized contributor to poor fetal outcomes: a population-based study of 78,552 pregnancies
    Peter E Fischer
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, USA
    J Trauma 71:90-3. 2011
    ..The purpose of this study was to determine the association of both minor and severe injury on fetal demise and prematurity/low birth weight (LBW) in a large population-based study using robust state databases...
  51. doi request reprint Impact of decompressive craniectomy on functional outcome after severe traumatic brain injury
    Regan F Williams
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Trauma 66:1570-4; discussion 1574-6. 2009
    ..The purpose of this study was to evaluate the efficacy of DC on functional outcome after severe TBI in the largest single institutional series reported in the literature...
  52. ncbi request reprint The utility of serial computed tomography imaging of blunt splenic injury: still worth a second look?
    Jordan A Weinberg
    Department of Surgery, University of Alabama at Birmingham, USA
    J Trauma 62:1143-7; discussion 1147-8. 2007
    ..The purpose of this study was to reevaluate the clinical practice of serial CT imaging within the context of an institutional protocol for the nonoperative management (NOM) of BSI...
  53. ncbi request reprint Gender disparity in ventilator-associated pneumonia following trauma: Identifying risk factors for mortality
    John P Sharpe
    From the Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee
    J Trauma Acute Care Surg 77:161-5. 2014
    ..The purposes of this study were to evaluate the impact of VAP and gender on outcome and to determine which characteristics of severe VAP predict mortality in trauma patients...
  54. doi request reprint Propofol infusion syndrome: a lethal condition in critically injured patients eliminated by a simple screening protocol
    Thomas J Schroeppel
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, United States Electronic address
    Injury 45:245-9. 2014
    ..We sought to determine the incidence of PIS in trauma patients and evaluate the efficacy of a prospective screening protocol in this patient population...
  55. ncbi request reprint Descending necrotizing mediastinitis: unique complication of central venous catheterization
    Francis J Caputo
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey, USA
    Surg Infect (Larchmt) 8:611-4. 2007
    ..However, these devices are not without complications. We describe the first reported case of descending necrotizing mediastinitis secondary to central venous catheterization without evidence of associated vascular perforation...
  56. ncbi request reprint Relationship between disruption of the unstirred mucus layer and intestinal restitution in loss of gut barrier function after trauma hemorrhagic shock
    Bobby Rupani
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, USA
    Surgery 141:481-9. 2007
    ..The factors involved in shock-induced loss of gut barrier function remain to be defined fully and studies investigating gut injury have focused primarily on the systemic side of the intestine...
  57. ncbi request reprint Admission red cell distribution width: a novel predictor of massive transfusion after injury
    Elena M Paulus
    Division of Trauma and Critical Care, Department of Surgery, The University of Tennessee Health, Science Center, Memphis, Tennessee, USA
    Am Surg 80:685-9. 2014
    ..The association between aRDW and mortality in trauma patients may be explained by acute hemorrhage rather than chronic health status. ..
  58. ncbi request reprint How to Increase the Burden on Trauma Centers: Implement the 80-hour Work Week
    Thomas J Schroeppel
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Am Surg 80:659-63. 2014
    ..This study adds to the mounting evidence that the implementation of the limits on work hours does not lead to better outcomes. ..
  59. doi request reprint Effectiveness of pseudoephedrine as adjunctive therapy for neurogenic shock after acute spinal cord injury: a case series
    G Christopher Wood
    Department of Clinical Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee
    Pharmacotherapy 34:89-93. 2014
    ..To evaluate the effectiveness of pseudoephedrine as adjunctive therapy for neurogenic shock in patients with acute spinal cord injury (SCI)...
  60. doi request reprint Optimal outcomes for patients with blunt cerebrovascular injury (BCVI): tailoring treatment to the lesion
    Jennifer M DiCocco
    Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Am Coll Surg 212:549-57; discussion 557-9. 2011
    ..Endovascular therapy in these lesions has increased without reports of outcomes. We sought to determine ischemic stroke and death rates after BCVI with and without endovascular treatment...
  61. ncbi request reprint Prosthetic vascular conduit in contaminated fields: a new technology to decrease ePTFE infections
    Peter E Fischer
    College of Medicine, Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Am Surg 74:524-8; discussion 528-9. 2008
    ..In vitro, the grafts provide a slow elution of antibiotics that provide resistance from infection by SA and SE for up to 2 weeks after graft insertion...
  62. pmc Insurance type is a determinant of 2-year mortality after non-neurologic trauma
    Ben L Zarzaur
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Surg Res 160:196-201. 2010
    ..Less is known about the influence of insurance type and long-term mortality following non-NEURO-TRA. We hypothesized that NO-INS would be associated with 2-y mortality after moderate to severe injury...
  63. doi request reprint Prophylactic antibiotic days as a predictor of sensitivity patterns in Acinetobacter pneumonia
    Parth B Amin
    Department of Surgery, University of Tennessee Health Science Center, 910 Madison Avenue, Memphis, TN 38163, USA
    Surg Infect (Larchmt) 12:33-8. 2011
    ..The purpose of this study was to evaluate the change in Acinetobacter sensitivity over time and determine which risk factors predict resistance in trauma patients...
  64. pmc Improving outcomes following penetrating colon wounds: application of a clinical pathway
    Preston R Miller
    Department of Surgery, The University of Tennessee Health Science Center, Memphis, 38163, USA
    Ann Surg 235:775-81. 2002
    ..Based on these outcomes, a clinical pathway for management of destructive colon wounds was developed. The results of the implementation of this pathway are the focus of this report...
  65. doi request reprint Impact of motorcycle helmets and state laws on society's burden: a national study
    Martin A Croce
    Department of Surgery University of Tennessee Health Science Center Memphis, TN, USA
    Ann Surg 250:390-4. 2009
    ..To analyze a large national database, the National Trauma Data Bank, regarding the contribution of motorcycle helmet use to outcome and the efficacy of state helmet laws...
  66. pmc Microvascular response to red blood cell transfusion in trauma patients
    Jordan A Weinberg
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38103, USA
    Shock 37:276-81. 2012
    ..Bedside sublingual imaging may have the potential to detect subtle perfusion defects and ultimately inform clinical decision making with respect to transfusion...
  67. ncbi request reprint Burns, bacterial translocation, gut barrier function, and failure
    Louis J Magnotti
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey 07103, USA
    J Burn Care Rehabil 26:383-91. 2005
    ..Thus, the goal of this review will be to provide a perspective on the evolution of the gut hypothesis of systemic inflammation and distant organ dysfunction...
  68. pmc Pancreatic duct ligation reduces lung injury following trauma and hemorrhagic shock
    David B Cohen
    Department of Surgery, University of Medicine, and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07103, USA
    Ann Surg 240:885-91. 2004
    ..This hypothesis was tested by examining the effect of PDL on T/HS-induced intestinal injury, lung injury, and RBC deformability...
  69. ncbi request reprint Influence of gut microflora on mesenteric lymph cytokine production in rats with hemorrhagic shock
    Weidun Guo
    Department of Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey 07103 2714, USA
    J Trauma 52:1178-85; disciussion 1185. 2002
    ..The aim of the present study was to test the hypothesis that the resident gut microflora play a role in modulating gut cytokine production under normal circumstances and in response to tissue injury with or without hemorrhagic shock...
  70. doi request reprint The evolution of blunt splenic injury: resolution and progression
    Stephanie A Savage
    Department of General Surgery, Wilford Hall Medical Center, Lackland AFB, Texas, USA
    J Trauma 64:1085-91; discussion 1091-2. 2008
    ..Our hypothesis was that time to healing is related to severity of BSI...