Research Topics
| V A MagnottaSummaryAffiliation: University of Iowa Country: USA Publications
Research Grants
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Detail Information
Publications
Structural MR image processing using the BRAINS2 toolboxVincent A Magnotta
Mental Health Clinical Research Center, The University of Iowa Hospitals and Clinics, Room 2911 JPP, 200 Hawkins Drive, Iowa City, IA 52242, USA
Comput Med Imaging Graph 26:251-64. 2002..These features are described in detail, as well as the reliability of these procedures...
Detecting activity-evoked pH changes in human brainVincent A Magnotta
Department of Radiology, University of Iowa, Iowa City, IA 52242, USA
Proc Natl Acad Sci U S A 109:8270-3. 2012..Furthermore, they suggest a unique functional imaging strategy based on pH that is independent of traditional functional MRI contrast mechanisms...
Investigating connectivity between the cerebellum and thalamus in schizophrenia using diffusion tensor tractography: a pilot studyVincent A Magnotta
Department of Radiology, The University of Iowa, Iowa, Iowa City, IA 52242, USA
Psychiatry Res 163:193-200. 2008..The FA values along the defined fiber tracts were not overall reduced but exhibited a reduction in the anisotropy in the region in the superior cerebellar peduncles projecting towards the red nucleus...- Quantitative in vivo measurement of gyrification in the human brain: changes associated with agingV A Magnotta
Mental Health Clinical Research Center, The University of Iowa College of Medicine and Hospitals and Clinics, Iowa City 52242, USA
Cereb Cortex 9:151-60. 1999..Measurements of sulcal and gyral shape may be useful in studying the mechanisms of both neurodevelopmental and neurodegenerative changes that occur during brain maturation and aging... - Measurement of Signal-to-Noise and Contrast-to-Noise in the fBIRN Multicenter Imaging StudyVincent A Magnotta
Department of Radiology, University of Iowa, 0453 D JCP, Iowa City, IA 52242, USA
J Digit Imaging 19:140-7. 2006..5-108.7 at 3 T and 50.8 at 4 T). Similar results were obtained for CNR measurements between gray/white matter at 1.5 T (9.5-10.2), again increasing at higher fields (10.1-28.9 at 3 T and 10.9 at 4 T)... - Subcortical, cerebellar, and magnetic resonance based consistent brain image registrationVincent A Magnotta
Iowa Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa, Iowa City, IA 52242, USA
Neuroimage 19:233-45. 2003..Furthermore, statistically significant improvements for all structures were achieved using the LI-SI algorithm compared to the intensity-only algorithm... - Evaluation of the GTRACT diffusion tensor tractography algorithm: a validation and reliability studyPeng Cheng
Department of Radiology, Georgetown University, Washington, DC 20007, USA
Neuroimage 31:1075-85. 2006..The results demonstrate that the GTRACT algorithm is less sensitive to image noise and more capable of handling areas of complex fiber crossing, compared to conventional streamline methods... - Registration and machine learning-based automated segmentation of subcortical and cerebellar brain structuresStephanie Powell
Department of Radiology, The University of Iowa, Iowa City, Iowa 52242 1057, USA
Neuroimage 39:238-47. 2008..Results show that the machine learning methods outperform the template and probability-based methods. Utilization of these automated segmentation methods may be as reliable as manual raters and require no rater intervention... - Pixel analysis of MR perfusion imaging in predicting radiation therapy outcome in cervical cancerN A Mayr
Division of Radiation Oncology, Department of Radiology, The University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
J Magn Reson Imaging 12:1027-33. 2000..J. Magn. Reson. Imaging 2000;12:1027-1033... - Challenges assessing clinical endpoints in early Huntington diseaseJane S Paulsen
Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242 1000, USA
Mov Disord 25:2595-603. 2010..We conclude that future clinical trials designed for very early disease will require the development of new and more sensitive measures of real-life function... - Marijuana alters the human cerebellar clockDANIEL S O'LEARY
Department of Psychiatry, University of Iowa Hospital and Clinic, Iowa City, IA 52242, USA
Neuroreport 14:1145-51. 2003..Smoking marijuana appears to accelerate a cerebellar clock altering self-paced behaviors... - Automated hexahedral meshing of anatomic structures using deformable registrationNicole M Grosland
Department of Biomedical Engineering, The University of Iowa, Iowa City, IA, USA
Comput Methods Biomech Biomed Engin 12:35-43. 2009..Furthermore, the distance between the target surface and the final mapped mesh were measured. The results have satisfactorily proven the applicability of the proposed method... - IA-FEMesh: an open-source, interactive, multiblock approach to anatomic finite element model developmentNicole M Grosland
Department of Biomedical Engineering, The University of Iowa, Iowa City, IA 52242, United States
Comput Methods Programs Biomed 94:96-107. 2009..While these tools have been developed, initially, in the context of skeletal structures they can be applied to countless applications... - Ia-FEMesh: anatomic FE models--a check of mesh accuracy and validityNicole A Devries
The University of Iowa Iowa City, IA 52242, USA
Iowa Orthop J 29:48-54. 2009.... - Long-term outcome of brain structure in premature infants: effects of liberal vs restricted red blood cell transfusionsPeg C Nopoulos
University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
Arch Pediatr Adolesc Med 165:443-50. 2011..To assess the long-term outcome of brain structure in preterm infants, at an average age of 12 years, who received a red blood cell transfusion for anemia of prematurity... - Cerebral cortex structure in prodromal Huntington diseasePeggy C Nopoulos
Department of Psychiatry, University of Iowa Roy and Lucille Carver College of Medicine, Iowa City, IA 52242, USA
Neurobiol Dis 40:544-54. 2010..Early in the course of HD, the cortex shows changes that are manifest as cortical thinning and are most robust in the posterior and superior regions of the cerebrum... - Fully automated analysis using BRAINS: AutoWorkupRonald Pierson
The University of Iowa Roy and Lucille Carver College of Medicine, Department of Psychiatry, Iowa City, IA 52242, USA
Neuroimage 54:328-36. 2011..Application of AutoWorkup for the analysis of data from the 32-site, multivendor PREDICT-HD study yield estimates of reliability to be greater than or equal to 0.90 for all tissues and regions... - Striatal and white matter predictors of estimated diagnosis for Huntington diseaseJane S Paulsen
University of Iowa Roy and Lucille Carver College of Medicine, Department of Psychiatry, Iowa City, IA, United States
Brain Res Bull 82:201-7. 2010.... - Global cerebral blood flow in relation to cognitive performance and reserve in subjects with mild memory deficitsLaura L Boles Ponto
Positron Emission Tomography Imaging Center, Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa, IA 52242, USA
Mol Imaging Biol 8:363-72. 2006..This study was undertaken to explore the mechanisms underlying cognitive reserve in subjects with mild memory deficits by using positron emission tomography (PET)... - Morphology of the cerebral cortex in preclinical Huntington's diseasePeg Nopoulos
Department of Psychiatry, University of Iowa Roy and Lucille Carver College of Medicine, Iowa City, IA, USA
Am J Psychiatry 164:1428-34. 2007..Cortical morphology was evaluated in subjects with known gene expansion for Huntington's disease and no manifest disease... - Donepezil effects on cerebral blood flow in older adults with mild cognitive deficitsXiying Chen
Department of Radiology, The Roy J. and Lucille A. Carver College of Medicine, 500 Newton Rd, Iowa City, IA 52242-1000, USA
J Neuropsychiatry Clin Neurosci 18:178-85. 2006..These findings suggest that donepezil treatment may be associated with a relative maintenance of CBF and improved list-learning... - Effects of smoking marijuana on focal attention and brain blood flowDANIEL S O'LEARY
Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, The University of Iowa, Iowa 52242, USA
Hum Psychopharmacol 22:135-48. 2007..These data indicate that marijuana has dramatic direct effects on rCBF, but causes relatively little change in the normal pattern of task-related rCBF on this auditory focused attention task... - Toward fully automated processing of dynamic susceptibility contrast perfusion MRI for acute ischemic cerebral strokeJinsuh Kim
Department of Radiology, University of Iowa, 200 Hawkins Dr, Iowa City, IA 52242, USA
Comput Methods Programs Biomed 98:204-13. 2010..Our streamlined method also offers promise for further development of automated quantitative analysis of the ischemic penumbra... - Validation of phalanx bone three-dimensional surface segmentation from computed tomography images using laser scanningNicole A Devries
Department of Biomedical Engineering, Center for Computer Aided Design, The University of Iowa, Iowa City, IA 52242, USA
Skeletal Radiol 37:35-42. 2008..To examine the validity of manually defined bony regions of interest from computed tomography (CT) scans... - Semi-automated phalanx bone segmentation using the expectation maximization algorithmAustin J Ramme
Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA
J Digit Imaging 22:483-91. 2009.... - Manual and automated measurement of the whole thalamus and mediodorsal nucleus using magnetic resonance imagingRuth Spinks
Mental Health-Clinical Research Center, University of Iowa, Iowa City 52242, USA
Neuroimage 17:631-42. 2002..The ANN provides an efficient automated method, making studies using larger sample sizes more feasible... - Globus pallidus volume is related to symptom severity in neuroleptic naive patients with schizophreniaRuth Spinks
Schizophrenia Research Center, University of Iowa, Iowa City, IA 52242, United States
Schizophr Res 73:229-33. 2005..The volume for the GP, GPe, and internal segment (GPi) did not differ between groups... - CAG-repeat length and the age of onset in Huntington disease (HD): a review and validation study of statistical approachesDouglas R Langbehn
Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242 1000, USA
Am J Med Genet B Neuropsychiatr Genet 153:397-408. 2010..The Langbehn et al. model appears accurate enough to have substantial utility in various research contexts. We also emphasize remaining caveats, many of which are relevant for any direct application to genetic counseling... - Predicting control of primary tumor and survival by DCE MRI during early therapy in cervical cancerWilliam T C Yuh
Department of Radiology, Ohio State University, Columbus, Ohio 43210, USA
Invest Radiol 44:343-50. 2009..To assess the early predictive power of MRI perfusion and volume parameters, during early treatment of cervical cancer, for primary tumor control and disease-free-survival... - Automated bony region identification using artificial neural networks: reliability and validation measurementsEsther E Gassman
Department of Biomedical Engineering, Seamans Center for the Engineering Arts and Sciences, The University of Iowa, Iowa City, IA 52242, USA
Skeletal Radiol 37:313-9. 2008.... - Magnetic resonance imaging correlates of set shiftingJoel H Kramer
Department of Neurology, University of California San Francisco, San Francisco, CA 94143, USA
J Int Neuropsychol Soc 13:386-92. 2007..Follow-up analyses indicated that frontal contributions to shifting were not related to working memory. Results highlight the importance of carefully controlling for component cognitive processes when studying executive functioning... - Reduced thalamic volume in first-episode non-affective psychosis: correlations with clinical variables, symptomatology and cognitive functioningBenedicto Crespo-Facorro
University Hospital Marques de Valdecilla, Department of Psychiatry, Planta 2 a, Edificio 2 de Noviembre Avda, Valdecilla s n, 39008, Santander, Spain
Neuroimage 35:1613-23. 2007..However, further investigations are warranted to fully clarify the relationship between those structural anomalies and clinical and cognitive outcomes... - Inter- and intraoperator reliability of brain tissue measures using magnetic resonance imagingGaku Okugawa
Dept of Neuropsychiatry, Kansai Medical University, 10 15 Fumizonocho Moriguchi, Osaka 570 8506, Japan
Eur Arch Psychiatry Clin Neurosci 253:301-6. 2003..971 and 0.999. The segmentation and measurement are useful for volumetric studies in the human brain using BRAINS... - MR imaging-based volumetry in patients with early-treated phenylketonuriaNadine H Pfaendner
Division of Neuroradiology, Department of Neurology, University of Heidelberg Medical Center, Heidelberg, Germany
AJNR Am J Neuroradiol 26:1681-5. 2005..CONCLUSION: The most severely affected brain structures in early-treated patients with phenylketonuria regarding volume loss are the cerebrum, corpus callosum, hippocampus, and pons...
Research Grants
- BRAINS Morphology and Image AnalysisVincent Magnotta; Fiscal Year: 2007....
- BRAINS Morphology and Image AnalysisVincent Magnotta; Fiscal Year: 2007..abstract_text> ..
- BRAINS Morphology and Image AnalysisVincent Magnotta; Fiscal Year: 2009....