V A Magnotta

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi request reprint Structural MR image processing using the BRAINS2 toolbox
    Vincent A Magnotta
    Mental Health Clinical Research Center, The University of Iowa Hospitals and Clinics, Room 2911 JPP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Comput Med Imaging Graph 26:251-64. 2002
  2. pmc Detecting activity-evoked pH changes in human brain
    Vincent A Magnotta
    Department of Radiology, University of Iowa, Iowa City, IA 52242, USA
    Proc Natl Acad Sci U S A 109:8270-3. 2012
  3. doi request reprint Investigating connectivity between the cerebellum and thalamus in schizophrenia using diffusion tensor tractography: a pilot study
    Vincent A Magnotta
    Department of Radiology, The University of Iowa, Iowa, Iowa City, IA 52242, USA
    Psychiatry Res 163:193-200. 2008
  4. ncbi request reprint Quantitative in vivo measurement of gyrification in the human brain: changes associated with aging
    V A Magnotta
    Mental Health Clinical Research Center, The University of Iowa College of Medicine and Hospitals and Clinics, Iowa City 52242, USA
    Cereb Cortex 9:151-60. 1999
  5. pmc Measurement of Signal-to-Noise and Contrast-to-Noise in the fBIRN Multicenter Imaging Study
    Vincent A Magnotta
    Department of Radiology, University of Iowa, 0453 D JCP, Iowa City, IA 52242, USA
    J Digit Imaging 19:140-7. 2006
  6. ncbi request reprint Subcortical, cerebellar, and magnetic resonance based consistent brain image registration
    Vincent A Magnotta
    Iowa Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa, Iowa City, IA 52242, USA
    Neuroimage 19:233-45. 2003
  7. ncbi request reprint Evaluation of the GTRACT diffusion tensor tractography algorithm: a validation and reliability study
    Peng Cheng
    Department of Radiology, Georgetown University, Washington, DC 20007, USA
    Neuroimage 31:1075-85. 2006
  8. pmc Registration and machine learning-based automated segmentation of subcortical and cerebellar brain structures
    Stephanie Powell
    Department of Radiology, The University of Iowa, Iowa City, Iowa 52242 1057, USA
    Neuroimage 39:238-47. 2008
  9. ncbi request reprint Pixel analysis of MR perfusion imaging in predicting radiation therapy outcome in cervical cancer
    N A Mayr
    Division of Radiation Oncology, Department of Radiology, The University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
    J Magn Reson Imaging 12:1027-33. 2000
  10. pmc Challenges assessing clinical endpoints in early Huntington disease
    Jane S Paulsen
    Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242 1000, USA
    Mov Disord 25:2595-603. 2010

Research Grants

  1. BRAINS Morphology and Image Analysis
    Vincent Magnotta; Fiscal Year: 2007
  2. BRAINS Morphology and Image Analysis
    Vincent Magnotta; Fiscal Year: 2007
  3. BRAINS Morphology and Image Analysis
    Vincent Magnotta; Fiscal Year: 2009

Detail Information

Publications34

  1. ncbi request reprint Structural MR image processing using the BRAINS2 toolbox
    Vincent A Magnotta
    Mental Health Clinical Research Center, The University of Iowa Hospitals and Clinics, Room 2911 JPP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Comput Med Imaging Graph 26:251-64. 2002
    ..These features are described in detail, as well as the reliability of these procedures...
  2. pmc Detecting activity-evoked pH changes in human brain
    Vincent A Magnotta
    Department of Radiology, University of Iowa, Iowa City, IA 52242, USA
    Proc Natl Acad Sci U S A 109:8270-3. 2012
    ..Furthermore, they suggest a unique functional imaging strategy based on pH that is independent of traditional functional MRI contrast mechanisms...
  3. doi request reprint Investigating connectivity between the cerebellum and thalamus in schizophrenia using diffusion tensor tractography: a pilot study
    Vincent A Magnotta
    Department of Radiology, The University of Iowa, Iowa, Iowa City, IA 52242, USA
    Psychiatry Res 163:193-200. 2008
    ..The FA values along the defined fiber tracts were not overall reduced but exhibited a reduction in the anisotropy in the region in the superior cerebellar peduncles projecting towards the red nucleus...
  4. ncbi request reprint Quantitative in vivo measurement of gyrification in the human brain: changes associated with aging
    V A Magnotta
    Mental Health Clinical Research Center, The University of Iowa College of Medicine and Hospitals and Clinics, Iowa City 52242, USA
    Cereb Cortex 9:151-60. 1999
    ..Measurements of sulcal and gyral shape may be useful in studying the mechanisms of both neurodevelopmental and neurodegenerative changes that occur during brain maturation and aging...
  5. pmc Measurement of Signal-to-Noise and Contrast-to-Noise in the fBIRN Multicenter Imaging Study
    Vincent A Magnotta
    Department of Radiology, University of Iowa, 0453 D JCP, Iowa City, IA 52242, USA
    J Digit Imaging 19:140-7. 2006
    ..5-108.7 at 3 T and 50.8 at 4 T). Similar results were obtained for CNR measurements between gray/white matter at 1.5 T (9.5-10.2), again increasing at higher fields (10.1-28.9 at 3 T and 10.9 at 4 T)...
  6. ncbi request reprint Subcortical, cerebellar, and magnetic resonance based consistent brain image registration
    Vincent A Magnotta
    Iowa Mental Health Clinical Research Center, Department of Psychiatry, University of Iowa, Iowa City, IA 52242, USA
    Neuroimage 19:233-45. 2003
    ..Furthermore, statistically significant improvements for all structures were achieved using the LI-SI algorithm compared to the intensity-only algorithm...
  7. ncbi request reprint Evaluation of the GTRACT diffusion tensor tractography algorithm: a validation and reliability study
    Peng Cheng
    Department of Radiology, Georgetown University, Washington, DC 20007, USA
    Neuroimage 31:1075-85. 2006
    ..The results demonstrate that the GTRACT algorithm is less sensitive to image noise and more capable of handling areas of complex fiber crossing, compared to conventional streamline methods...
  8. pmc Registration and machine learning-based automated segmentation of subcortical and cerebellar brain structures
    Stephanie Powell
    Department of Radiology, The University of Iowa, Iowa City, Iowa 52242 1057, USA
    Neuroimage 39:238-47. 2008
    ..Results show that the machine learning methods outperform the template and probability-based methods. Utilization of these automated segmentation methods may be as reliable as manual raters and require no rater intervention...
  9. ncbi request reprint Pixel analysis of MR perfusion imaging in predicting radiation therapy outcome in cervical cancer
    N A Mayr
    Division of Radiation Oncology, Department of Radiology, The University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
    J Magn Reson Imaging 12:1027-33. 2000
    ..J. Magn. Reson. Imaging 2000;12:1027-1033...
  10. pmc Challenges assessing clinical endpoints in early Huntington disease
    Jane S Paulsen
    Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242 1000, USA
    Mov Disord 25:2595-603. 2010
    ..We conclude that future clinical trials designed for very early disease will require the development of new and more sensitive measures of real-life function...
  11. ncbi request reprint Marijuana alters the human cerebellar clock
    DANIEL S O'LEARY
    Department of Psychiatry, University of Iowa Hospital and Clinic, Iowa City, IA 52242, USA
    Neuroreport 14:1145-51. 2003
    ..Smoking marijuana appears to accelerate a cerebellar clock altering self-paced behaviors...
  12. doi request reprint Automated hexahedral meshing of anatomic structures using deformable registration
    Nicole M Grosland
    Department of Biomedical Engineering, The University of Iowa, Iowa City, IA, USA
    Comput Methods Biomech Biomed Engin 12:35-43. 2009
    ..Furthermore, the distance between the target surface and the final mapped mesh were measured. The results have satisfactorily proven the applicability of the proposed method...
  13. pmc IA-FEMesh: an open-source, interactive, multiblock approach to anatomic finite element model development
    Nicole M Grosland
    Department of Biomedical Engineering, The University of Iowa, Iowa City, IA 52242, United States
    Comput Methods Programs Biomed 94:96-107. 2009
    ..While these tools have been developed, initially, in the context of skeletal structures they can be applied to countless applications...
  14. pmc Ia-FEMesh: anatomic FE models--a check of mesh accuracy and validity
    Nicole A Devries
    The University of Iowa Iowa City, IA 52242, USA
    Iowa Orthop J 29:48-54. 2009
    ....
  15. pmc Long-term outcome of brain structure in premature infants: effects of liberal vs restricted red blood cell transfusions
    Peg C Nopoulos
    University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Arch Pediatr Adolesc Med 165:443-50. 2011
    ..To assess the long-term outcome of brain structure in preterm infants, at an average age of 12 years, who received a red blood cell transfusion for anemia of prematurity...
  16. pmc Cerebral cortex structure in prodromal Huntington disease
    Peggy C Nopoulos
    Department of Psychiatry, University of Iowa Roy and Lucille Carver College of Medicine, Iowa City, IA 52242, USA
    Neurobiol Dis 40:544-54. 2010
    ..Early in the course of HD, the cortex shows changes that are manifest as cortical thinning and are most robust in the posterior and superior regions of the cerebrum...
  17. doi request reprint Fully automated analysis using BRAINS: AutoWorkup
    Ronald Pierson
    The University of Iowa Roy and Lucille Carver College of Medicine, Department of Psychiatry, Iowa City, IA 52242, USA
    Neuroimage 54:328-36. 2011
    ..Application of AutoWorkup for the analysis of data from the 32-site, multivendor PREDICT-HD study yield estimates of reliability to be greater than or equal to 0.90 for all tissues and regions...
  18. pmc Striatal and white matter predictors of estimated diagnosis for Huntington disease
    Jane S Paulsen
    University of Iowa Roy and Lucille Carver College of Medicine, Department of Psychiatry, Iowa City, IA, United States
    Brain Res Bull 82:201-7. 2010
    ....
  19. ncbi request reprint Global cerebral blood flow in relation to cognitive performance and reserve in subjects with mild memory deficits
    Laura L Boles Ponto
    Positron Emission Tomography Imaging Center, Department of Radiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa, IA 52242, USA
    Mol Imaging Biol 8:363-72. 2006
    ..This study was undertaken to explore the mechanisms underlying cognitive reserve in subjects with mild memory deficits by using positron emission tomography (PET)...
  20. ncbi request reprint Morphology of the cerebral cortex in preclinical Huntington's disease
    Peg Nopoulos
    Department of Psychiatry, University of Iowa Roy and Lucille Carver College of Medicine, Iowa City, IA, USA
    Am J Psychiatry 164:1428-34. 2007
    ..Cortical morphology was evaluated in subjects with known gene expansion for Huntington's disease and no manifest disease...
  21. ncbi request reprint Donepezil effects on cerebral blood flow in older adults with mild cognitive deficits
    Xiying Chen
    Department of Radiology, The Roy J and Lucille A Carver College of Medicine, 500 Newton Rd, Iowa City, IA 52242 1000, USA
    J Neuropsychiatry Clin Neurosci 18:178-85. 2006
    ..These findings suggest that donepezil treatment may be associated with a relative maintenance of CBF and improved list-learning...
  22. ncbi request reprint Effects of smoking marijuana on focal attention and brain blood flow
    DANIEL S O'LEARY
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, The University of Iowa, Iowa 52242, USA
    Hum Psychopharmacol 22:135-48. 2007
    ..These data indicate that marijuana has dramatic direct effects on rCBF, but causes relatively little change in the normal pattern of task-related rCBF on this auditory focused attention task...
  23. doi request reprint Toward fully automated processing of dynamic susceptibility contrast perfusion MRI for acute ischemic cerebral stroke
    Jinsuh Kim
    Department of Radiology, University of Iowa, 200 Hawkins Dr, Iowa City, IA 52242, USA
    Comput Methods Programs Biomed 98:204-13. 2010
    ..Our streamlined method also offers promise for further development of automated quantitative analysis of the ischemic penumbra...
  24. ncbi request reprint Validation of phalanx bone three-dimensional surface segmentation from computed tomography images using laser scanning
    Nicole A Devries
    Department of Biomedical Engineering, Center for Computer Aided Design, The University of Iowa, Iowa City, IA 52242, USA
    Skeletal Radiol 37:35-42. 2008
    ..To examine the validity of manually defined bony regions of interest from computed tomography (CT) scans...
  25. pmc Semi-automated phalanx bone segmentation using the expectation maximization algorithm
    Austin J Ramme
    Carver College of Medicine, The University of Iowa, Iowa City, IA 52242, USA
    J Digit Imaging 22:483-91. 2009
    ....
  26. ncbi request reprint Manual and automated measurement of the whole thalamus and mediodorsal nucleus using magnetic resonance imaging
    Ruth Spinks
    Mental Health Clinical Research Center, University of Iowa, Iowa City 52242, USA
    Neuroimage 17:631-42. 2002
    ..The ANN provides an efficient automated method, making studies using larger sample sizes more feasible...
  27. ncbi request reprint Globus pallidus volume is related to symptom severity in neuroleptic naive patients with schizophrenia
    Ruth Spinks
    Schizophrenia Research Center, University of Iowa, Iowa City, IA 52242, United States
    Schizophr Res 73:229-33. 2005
    ..The volume for the GP, GPe, and internal segment (GPi) did not differ between groups...
  28. pmc CAG-repeat length and the age of onset in Huntington disease (HD): a review and validation study of statistical approaches
    Douglas R Langbehn
    Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242 1000, USA
    Am J Med Genet B Neuropsychiatr Genet 153:397-408. 2010
    ..The Langbehn et al. model appears accurate enough to have substantial utility in various research contexts. We also emphasize remaining caveats, many of which are relevant for any direct application to genetic counseling...
  29. pmc Predicting control of primary tumor and survival by DCE MRI during early therapy in cervical cancer
    William T C Yuh
    Department of Radiology, Ohio State University, Columbus, Ohio 43210, USA
    Invest Radiol 44:343-50. 2009
    ..To assess the early predictive power of MRI perfusion and volume parameters, during early treatment of cervical cancer, for primary tumor control and disease-free-survival...
  30. doi request reprint Automated bony region identification using artificial neural networks: reliability and validation measurements
    Esther E Gassman
    Department of Biomedical Engineering, Seamans Center for the Engineering Arts and Sciences, The University of Iowa, Iowa City, IA 52242, USA
    Skeletal Radiol 37:313-9. 2008
    ....
  31. pmc Magnetic resonance imaging correlates of set shifting
    Joel H Kramer
    Department of Neurology, University of California San Francisco, San Francisco, CA 94143, USA
    J Int Neuropsychol Soc 13:386-92. 2007
    ..Follow-up analyses indicated that frontal contributions to shifting were not related to working memory. Results highlight the importance of carefully controlling for component cognitive processes when studying executive functioning...
  32. ncbi request reprint Reduced thalamic volume in first-episode non-affective psychosis: correlations with clinical variables, symptomatology and cognitive functioning
    Benedicto Crespo-Facorro
    University Hospital Marques de Valdecilla, Department of Psychiatry, Planta 2 a, Edificio 2 de Noviembre Avda, Valdecilla s n, 39008, Santander, Spain
    Neuroimage 35:1613-23. 2007
    ..However, further investigations are warranted to fully clarify the relationship between those structural anomalies and clinical and cognitive outcomes...
  33. ncbi request reprint Inter- and intraoperator reliability of brain tissue measures using magnetic resonance imaging
    Gaku Okugawa
    Dept of Neuropsychiatry, Kansai Medical University, 10 15 Fumizonocho Moriguchi, Osaka 570 8506, Japan
    Eur Arch Psychiatry Clin Neurosci 253:301-6. 2003
    ..971 and 0.999. The segmentation and measurement are useful for volumetric studies in the human brain using BRAINS...
  34. ncbi request reprint MR imaging-based volumetry in patients with early-treated phenylketonuria
    Nadine H Pfaendner
    Division of Neuroradiology, Department of Neurology, University of Heidelberg Medical Center, Heidelberg, Germany
    AJNR Am J Neuroradiol 26:1681-5. 2005
    ..Our purpose was to specify the most severely affected brain structures in early treated phenylketonuria regarding volume loss and establish possible correlations between volume loss and plasma levels of phenylalanine (Phe)...

Research Grants4

  1. BRAINS Morphology and Image Analysis
    Vincent Magnotta; Fiscal Year: 2007
    ....
  2. BRAINS Morphology and Image Analysis
    Vincent Magnotta; Fiscal Year: 2007
    ..abstract_text> ..
  3. BRAINS Morphology and Image Analysis
    Vincent Magnotta; Fiscal Year: 2009
    ....