Lillian Maggio-Price

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Dual infection with Helicobacter bilis and Helicobacter hepaticus in p-glycoprotein-deficient mdr1a-/- mice results in colitis that progresses to dysplasia
    Lillian Maggio-Price
    Department of Comparative Medicine, School of Medicine, University of Washington, Seattle, WA 98195, USA
    Am J Pathol 166:1793-806. 2005
  2. ncbi request reprint Helicobacter infection is required for inflammation and colon cancer in SMAD3-deficient mice
    Lillian Maggio-Price
    Department of Comparative Medicine, University of Washington, 1959 Northeast Pacific Avenue, Seattle, WA 98195, USA
    Cancer Res 66:828-38. 2006
  3. pmc Bacterial infection of Smad3/Rag2 double-null mice with transforming growth factor-beta dysregulation as a model for studying inflammation-associated colon cancer
    Lillian Maggio-Price
    Department of Comparative Medicine, University of Washington, School of Medicine, Seattle, Washington 98195, USA
    Am J Pathol 174:317-29. 2009
  4. pmc Lack of effect of murine norovirus infection on a mouse model of bacteria-induced colon cancer
    Karen C Lencioni
    Department of Comparative Medicine, University of Washington, Seattle, Washington, USA
    Comp Med 61:219-26. 2011
  5. pmc Lineage targeted MHC-II transgenic mice demonstrate the role of dendritic cells in bacterial-driven colitis
    Lillian Maggio-Price
    Department of Comparative Medicine, University of Washington, Seattle, Washington 98195, USA
    Inflamm Bowel Dis 19:174-84. 2013
  6. pmc Murine norovirus increases atherosclerotic lesion size and macrophages in Ldlr(-/-) mice
    Jisun Paik
    Department of Comparative Medicine, University of Washington, Seattle, Washington, USA
    Comp Med 61:330-8. 2011
  7. pmc Helicobacter bilis infection accelerates and H. hepaticus infection delays the development of colitis in multiple drug resistance-deficient (mdr1a-/-) mice
    Lillian Maggio-Price
    Department of Comparative Medicine, School of Medicine, University of Washington, Box 357190, Seattle, WA 981295, USA
    Am J Pathol 160:739-51. 2002
  8. ncbi request reprint Serum biomarkers in a mouse model of bacterial-induced inflammatory bowel disease
    Anne E Torrence
    Washington National Primate Research Center, University of Washington, Seattle, Washington 98195, USA
    Inflamm Bowel Dis 14:480-90. 2008
  9. pmc Effects of murine norovirus infection on a mouse model of diet-induced obesity and insulin resistance
    Jisun Paik
    Department of Comparative Medicine, The University of Washington, Seattle, Washington, USA
    Comp Med 60:189-95. 2010
  10. doi request reprint High-fat diet-induced obesity exacerbates inflammatory bowel disease in genetically susceptible Mdr1a-/- male mice
    Jisun Paik
    Department of Comparative Medicine, and Nutritional Sciences Program, University of Washington, Seattle, WA, USA
    J Nutr 143:1240-7. 2013

Collaborators

Detail Information

Publications15

  1. pmc Dual infection with Helicobacter bilis and Helicobacter hepaticus in p-glycoprotein-deficient mdr1a-/- mice results in colitis that progresses to dysplasia
    Lillian Maggio-Price
    Department of Comparative Medicine, School of Medicine, University of Washington, Seattle, WA 98195, USA
    Am J Pathol 166:1793-806. 2005
    ..This animal model may have particular relevance to human IBD and colorectal cancer because certain human MDR1 polymorphisms have been linked to ulcerative colitis and increased risk for colorectal cancer...
  2. ncbi request reprint Helicobacter infection is required for inflammation and colon cancer in SMAD3-deficient mice
    Lillian Maggio-Price
    Department of Comparative Medicine, University of Washington, 1959 Northeast Pacific Avenue, Seattle, WA 98195, USA
    Cancer Res 66:828-38. 2006
    ....
  3. pmc Bacterial infection of Smad3/Rag2 double-null mice with transforming growth factor-beta dysregulation as a model for studying inflammation-associated colon cancer
    Lillian Maggio-Price
    Department of Comparative Medicine, University of Washington, School of Medicine, Seattle, Washington 98195, USA
    Am J Pathol 174:317-29. 2009
    ....
  4. pmc Lack of effect of murine norovirus infection on a mouse model of bacteria-induced colon cancer
    Karen C Lencioni
    Department of Comparative Medicine, University of Washington, Seattle, Washington, USA
    Comp Med 61:219-26. 2011
    ..In addition, MNV infection alone did not result in IBD or colon cancer. Therefore MNV infection alone or in conjunction with Helicobacter does not alter the development or progression of IBD or colon cancer in Smad3(-/-) mice...
  5. pmc Lineage targeted MHC-II transgenic mice demonstrate the role of dendritic cells in bacterial-driven colitis
    Lillian Maggio-Price
    Department of Comparative Medicine, University of Washington, Seattle, Washington 98195, USA
    Inflamm Bowel Dis 19:174-84. 2013
    ..The role of professional APC (macrophages and dendritic cells [DCs]) and nonprofessional APC (intestinal epithelial cells [IECs]) in microbial-driven intestinal inflammation remains controversial...
  6. pmc Murine norovirus increases atherosclerotic lesion size and macrophages in Ldlr(-/-) mice
    Jisun Paik
    Department of Comparative Medicine, University of Washington, Seattle, Washington, USA
    Comp Med 61:330-8. 2011
    ..Increased lesion size was associated with increased macrophages, suggesting that MNV may influence macrophage activation or accumulation in the lesion area...
  7. pmc Helicobacter bilis infection accelerates and H. hepaticus infection delays the development of colitis in multiple drug resistance-deficient (mdr1a-/-) mice
    Lillian Maggio-Price
    Department of Comparative Medicine, School of Medicine, University of Washington, Box 357190, Seattle, WA 981295, USA
    Am J Pathol 160:739-51. 2002
    ..mdr1a-/- mice infected with Helicobacter spp. may provide a useful tool to explore the pathogenesis of microbial-induced IBD in a model with a presumed epithelial cell "barrier" defect...
  8. ncbi request reprint Serum biomarkers in a mouse model of bacterial-induced inflammatory bowel disease
    Anne E Torrence
    Washington National Primate Research Center, University of Washington, Seattle, Washington 98195, USA
    Inflamm Bowel Dis 14:480-90. 2008
    ..Currently, there are limited noninvasive biomarkers for monitoring disease progression in animal IBD models, which are used extensively to develop new therapies and to understand IBD pathogenesis...
  9. pmc Effects of murine norovirus infection on a mouse model of diet-induced obesity and insulin resistance
    Jisun Paik
    Department of Comparative Medicine, The University of Washington, Seattle, Washington, USA
    Comp Med 60:189-95. 2010
    ..Further studies using other models of metabolic diseases are needed to provide additional information on the potential role this 'subclinical' virus might have on disease progression in mouse models of inflammatory diseases...
  10. doi request reprint High-fat diet-induced obesity exacerbates inflammatory bowel disease in genetically susceptible Mdr1a-/- male mice
    Jisun Paik
    Department of Comparative Medicine, and Nutritional Sciences Program, University of Washington, Seattle, WA, USA
    J Nutr 143:1240-7. 2013
    ..012; Fisher's exact test). Although a HFD and obesity were not associated with IBD in WT mice, our studies suggest that they are likely risk factors for IBD in a genetically susceptible host, such as Mdr1a(-/-) mice. ..
  11. pmc Interleukin-7 receptor blockade suppresses adaptive and innate inflammatory responses in experimental colitis
    Cynthia R Willis
    Department of Inflammation, Amgen, Inc, Seattle, WA, USA
    J Inflamm (Lond) 9:39. 2012
    ..abstract:..
  12. ncbi request reprint Changes in pharmacokinetics of anti-HIV protease inhibitors during pregnancy: the role of CYP3A and P-glycoprotein
    Anita A Mathias
    Department of Pharmaceutics, University of Washington, Box 357610, Seattle, WA 98195, USA
    J Pharmacol Exp Ther 316:1202-9. 2006
    ..If such upregulation of hepatic CYP3A activity occurs in pregnant women, it has important implications for dose adjustment of a variety of drugs ingested by pregnant women and cleared predominately via CYP3A metabolism...
  13. ncbi request reprint Vascular leak syndrome of Sprague-Dawley rats in a mandibular distraction osteogenesis study
    Carole R Baskin
    Department of Comparative Medicine, University of Washington, Seattle 98195, USA
    Comp Med 53:207-12. 2003
    ..Hence, the rat may be a useful animal model to h elp characterize the physiologic and molecular events that accompany this syndrome...
  14. ncbi request reprint Retinoic acid receptor beta2 inhibition of metastasis in mouse mammary gland xenografts
    Piper M Treuting
    Department of Pathology, University of Washington, Seattle 98195, USA
    Breast Cancer Res Treat 72:79-88. 2002
    ..000001). Our findings suggest that RARbeta2 may play a role in inhibiting the metastatic cascade in a mouse mammary gland xenograft tumor model and is a potential candidate for therapeutic intervention in human breast cancer...
  15. ncbi request reprint Neonatal co-infection with helicobacter species markedly accelerates the development of inflammation-associated colonic neoplasia in IL-10(-/-) mice
    Laura P Hale
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Helicobacter 12:598-604. 2007
    ..However, the long lead time required before development of inflammation-associated colon neoplasia in commonly used murine models of IBD slows the development of effective chemopreventative therapies...