Richard J Maddock
Affiliation: University of California
- Abnormal activity-dependent brain lactate and glutamate+glutamine responses in panic disorderRichard J Maddock
Department of Psychiatry, University of California Davis Medical Center, Sacramento, California 95817, USA
Biol Psychiatry 73:1111-9. 2013..However, prior studies in PD have not measured activity-dependent changes in brain metabolites other than lactate. Here we examine activity-dependent changes in both lactate and glutamate plus glutamine (glx) in PD...
- Vigorous exercise increases brain lactate and Glx (glutamate+glutamine): a dynamic 1H-MRS studyRichard J Maddock
Imaging Research Center, University of California Davis Medical Center, Sacramento, CA 95817, USA
Neuroimage 57:1324-30. 2011..The possible relevance of these findings to panic disorder and major depression is discussed...
- Activation of left posterior cingulate gyrus by the auditory presentation of threat-related words: an fMRI studyR J Maddock
Department of Psychiatry, University of California Davis, School of Medicine, Sacramento 95817, USA
Psychiatry Res 75:1-14. 1997..The retrosplenial cingulate region has recently been implicated in episodic memory processes. We discuss the possible role of the posterior cingulate cortex in processes involving emotion and memory and in anxiety disorders...
- The lactic acid response to alkalosis in panic disorder : an integrative reviewR J Maddock
Department of Psychiatry, University of California Davis School of Medicine, 95817, USA
J Neuropsychiatry Clin Neurosci 13:22-34. 2001..This review suggests a theoretical framework for future magnetic resonance spectroscopy studies that can test some of the predictions of these competing models...
- Elevated brain lactate responses to neural activation in panic disorder: a dynamic 1H-MRS studyR J Maddock
Department of Psychiatry, University of California Davis Medical Center, Sacramento, CA 95817, USA
Mol Psychiatry 14:537-45. 2009....
- Brain lactate responses during visual stimulation in fasting and hyperglycemic subjects: a proton magnetic resonance spectroscopy study at 1.5 TeslaRichard J Maddock
Department of Psychiatry and Behavioral Sciences, University of California Davis, Sacramento, CA 95817, USA
Psychiatry Res 148:47-54. 2006..5 T and show that variations in blood glucose across the normal range have little effect on this response...
- Posterior cingulate cortex activation by emotional words: fMRI evidence from a valence decision taskRichard J Maddock
Department of Psychiatry, University of California Davis Medical Center, 2230 Stockton Boulevard, Sacramento, CA 95817, USA
Hum Brain Mapp 18:30-41. 2003..The results also extend prior findings that evaluating emotional words consistently activates the subgenual cingulate cortex, and suggest a means of probing this region in patients with mood disorders...
- Brain regions showing increased activation by threat-related words in panic disorderRichard J Maddock
Department of Radiology, University of California Davis, 4801 X St, Sacramento, California 95817, USA
Neuroreport 14:325-8. 2003..The increased responsivity observed in the posterior cingulate and dorsolateral prefrontal cortices is consistent with the hypothesis that panic disorder patients engage in more extensive memory processing of threat-related stimuli...
- Separating subjective emotion from the perception of emotion-inducing stimuli: an fMRI studyAmy S Garrett
Department of Psychiatry, Stanford University School of Medicine, 401 Quarry Road, CA 94305 5795, USA
Neuroimage 33:263-74. 2006....
- Neurosarcoidosis and deliriumJames A Bourgeois
Department of Psychiatry and Behavioral Sciences, University of California Davis Medical Center, 2230 Stockton Blvd, Sacramento, CA 95817, USA
Psychosomatics 46:148-50. 2005
- Effects of lorazepam on the distribution of spatial attentionR B Post
Department of Psychology, University of California, Davis 95616, USA
Exp Clin Psychopharmacol 5:143-9. 1997..The possibility that lorazepam selectively impairs the disengage component of attentional movement is discussed...
- GABA concentration is reduced in visual cortex in schizophrenia and correlates with orientation-specific surround suppressionJong H Yoon
Department of Psychiatry and Imaging Research Center, University of California, Davis, Davis, California 95817, USA
J Neurosci 30:3777-81. 2010..10). These results suggest that a neocortical GABA deficit in subjects with schizophrenia leads to impaired cortical inhibition and that GABAergic synaptic transmission in visual cortex plays a critical role in OSSS...
- Remembering familiar people: the posterior cingulate cortex and autobiographical memory retrievalR J Maddock
Depaartment of Psychiatry, University of California Davis, Sacramento 65817, USA
Neuroscience 104:667-76. 2001..Our findings suggest that autobiographical memory retrieval tasks could be used to probe the functional status of the posterior cingulate cortex in patients with early Alzheimer's disease or at risk for that condition...
- Elevated serum lactate following hyperventilation during glucose infusion in panic disorderR J Maddock
Department of Psychiatry, University of California Davis School of Medicine
Biol Psychiatry 27:411-8. 1990..There was no evidence of a relationship between the increase in lactate or the associated decrease in phosphate and the level of anxiety produced by this procedure...
- Impaired recognition of facial expressions of emotion in Alzheimer's diseaseRita Hargrave
Department of Psychiatry, University of California, Davis, USA
J Neuropsychiatry Clin Neurosci 14:64-71. 2002..The authors conclude that patients with AD have deficits in recognizing facial emotions, which may be independent of their impairment in recognizing nonemotional features of faces...
- Brain Lactate and Photic Stimulation in Panic DisorderRICHARD MADDOCK; Fiscal Year: 2005..The results of this study will constrain the possible models that can account for this phenomenon and guide future studies of the underlying pathophysiology of panic disorder. ..
- MRS and fMRI Studies of Neurobiological Factors in Panic DisorderRICHARD MADDOCK; Fiscal Year: 2007..This project will test predictions of each theory about fear responses and brain metabolism in panic patients in order to better understand what causes panic disorder. ..