Paul MacLean

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. request reprint
    MacLean P, Bower J, Vadlamudi S, Osborne J, Bradfield J, Burden H, et al. Cholesteryl ester transfer protein expression prevents diet-induced atherosclerotic lesions in male db/db mice. Arterioscler Thromb Vasc Biol. 2003;23:1412-5 pubmed
    ..The expression of human CETP in db/db mice prevented the formation of diet-induced lesions, suggesting an antiatherogenic effect of CETP in the context of diabetic obesity. ..
  2. request reprint
    MacLean P, Vadlamudi S, MacDonald K, Pories W, Barakat H. Suppression of hepatic cholesteryl ester transfer protein expression in obese humans with the development of type 2 diabetes mellitus. J Clin Endocrinol Metab. 2005;90:2250-8 pubmed
    ..Thus, the suppressive effects of type 2 diabetes in obese subjects are observed in both men and women and may be due, at least in part, to a suppression of hepatic CETP expression. ..

Detail Information

Publications2

  1. request reprint
    MacLean P, Bower J, Vadlamudi S, Osborne J, Bradfield J, Burden H, et al. Cholesteryl ester transfer protein expression prevents diet-induced atherosclerotic lesions in male db/db mice. Arterioscler Thromb Vasc Biol. 2003;23:1412-5 pubmed
    ..The expression of human CETP in db/db mice prevented the formation of diet-induced lesions, suggesting an antiatherogenic effect of CETP in the context of diabetic obesity. ..
  2. request reprint
    MacLean P, Vadlamudi S, MacDonald K, Pories W, Barakat H. Suppression of hepatic cholesteryl ester transfer protein expression in obese humans with the development of type 2 diabetes mellitus. J Clin Endocrinol Metab. 2005;90:2250-8 pubmed
    ..Thus, the suppressive effects of type 2 diabetes in obese subjects are observed in both men and women and may be due, at least in part, to a suppression of hepatic CETP expression. ..