Rachel Mackey

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Hormone therapy, estrogen metabolism, and risk of breast cancer in the Women's Health Initiative Hormone Therapy Trial
    Rachel H Mackey
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Cancer Epidemiol Biomarkers Prev 21:2022-32. 2012
  2. pmc High-density lipoprotein cholesterol and particle concentrations, carotid atherosclerosis, and coronary events: MESA (multi-ethnic study of atherosclerosis)
    Rachel H Mackey
    University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania 15261, USA
    J Am Coll Cardiol 60:508-16. 2012
  3. pmc Distribution of 10-year and lifetime predicted risk for cardiovascular disease prior to surgery in the longitudinal assessment of bariatric surgery-2 study
    Rachel H Mackey
    University of Pittsburgh Graduate School of Public Health, Pennsylvania, USA
    Am J Cardiol 110:1130-7. 2012
  4. ncbi request reprint Calcifications, arterial stiffness and atherosclerosis
    Rachel H Mackey
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Adv Cardiol 44:234-44. 2007
  5. doi request reprint Weighing benefits for older runners
    Rachel H Mackey
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, A531 Crabtree Hall, 130 DeSoto St, Pittsburgh, PA 15261, USA
    Arch Intern Med 168:1948-9. 2008
  6. ncbi request reprint Hormone therapy, lipoprotein subclasses, and coronary calcification: the Healthy Women Study
    Rachel H Mackey
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Arch Intern Med 165:510-5. 2005
  7. pmc Reproductive hormones and obesity: 9 years of observation from the Study of Women's Health Across the Nation
    Kim Sutton-Tyrrell
    Department of Epidemiology, University of Pittsburgh, Pennsylvania 15261, USA
    Am J Epidemiol 171:1203-13. 2010
  8. pmc Augmentation pressure and subendocardial viability ratio are associated with microalbuminuria and with poor renal function in type 1 diabetes
    Catherine T Prince
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 3512 Fifth Avenue, Pittsburgh, PA 15213, USA
    Diab Vasc Dis Res 7:216-24. 2010
  9. ncbi request reprint Volumetric BMD and vascular calcification in middle-aged women: the Study of Women's Health Across the Nation
    Ghada N Farhat
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
    J Bone Miner Res 21:1839-46. 2006
  10. ncbi request reprint Low central nervous system serotonergic responsivity is associated with the metabolic syndrome and physical inactivity
    Matthew F Muldoon
    Divisions of Clinical Pharmacology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA
    J Clin Endocrinol Metab 89:266-71. 2004

Detail Information

Publications23

  1. pmc Hormone therapy, estrogen metabolism, and risk of breast cancer in the Women's Health Initiative Hormone Therapy Trial
    Rachel H Mackey
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Cancer Epidemiol Biomarkers Prev 21:2022-32. 2012
    ....
  2. pmc High-density lipoprotein cholesterol and particle concentrations, carotid atherosclerosis, and coronary events: MESA (multi-ethnic study of atherosclerosis)
    Rachel H Mackey
    University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania 15261, USA
    J Am Coll Cardiol 60:508-16. 2012
    ..The purpose of this study was to evaluate independent associations of high-density lipoprotein cholesterol (HDL-C) and particle (HDL-P) concentrations with carotid intima-media thickness (cIMT) and incident coronary heart disease (CHD)...
  3. pmc Distribution of 10-year and lifetime predicted risk for cardiovascular disease prior to surgery in the longitudinal assessment of bariatric surgery-2 study
    Rachel H Mackey
    University of Pittsburgh Graduate School of Public Health, Pennsylvania, USA
    Am J Cardiol 110:1130-7. 2012
    ..clinicaltrials.gov/ct2/results?term=NCT00465829)...
  4. ncbi request reprint Calcifications, arterial stiffness and atherosclerosis
    Rachel H Mackey
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Adv Cardiol 44:234-44. 2007
    ..CONCLUSION: Current evidence supports that medial calcification is associated with increases in arterial stiffness. The association between intimal (atherosclerotic-associated) calcification and arterial stiffness is less definitive...
  5. doi request reprint Weighing benefits for older runners
    Rachel H Mackey
    Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, A531 Crabtree Hall, 130 DeSoto St, Pittsburgh, PA 15261, USA
    Arch Intern Med 168:1948-9. 2008
  6. ncbi request reprint Hormone therapy, lipoprotein subclasses, and coronary calcification: the Healthy Women Study
    Rachel H Mackey
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Arch Intern Med 165:510-5. 2005
    ..To test this hypothesis, we evaluated differences in coronary calcification, lipids, and lipoprotein subclasses among HT users and nonusers in a longitudinal study of the menopause...
  7. pmc Reproductive hormones and obesity: 9 years of observation from the Study of Women's Health Across the Nation
    Kim Sutton-Tyrrell
    Department of Epidemiology, University of Pittsburgh, Pennsylvania 15261, USA
    Am J Epidemiol 171:1203-13. 2010
    ....
  8. pmc Augmentation pressure and subendocardial viability ratio are associated with microalbuminuria and with poor renal function in type 1 diabetes
    Catherine T Prince
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 3512 Fifth Avenue, Pittsburgh, PA 15213, USA
    Diab Vasc Dis Res 7:216-24. 2010
    ....
  9. ncbi request reprint Volumetric BMD and vascular calcification in middle-aged women: the Study of Women's Health Across the Nation
    Ghada N Farhat
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA
    J Bone Miner Res 21:1839-46. 2006
    ..Lower vBMD was related to high AC, but not to CAC, independent of age and shared risk factors between osteoporosis and cardiovascular disease...
  10. ncbi request reprint Low central nervous system serotonergic responsivity is associated with the metabolic syndrome and physical inactivity
    Matthew F Muldoon
    Divisions of Clinical Pharmacology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA
    J Clin Endocrinol Metab 89:266-71. 2004
    ..These findings reveal a heretofore unrecognized association between reduced central serotonergic responsivity and the metabolic syndrome...
  11. ncbi request reprint Lipoprotein subclasses and coronary artery calcium in postmenopausal women from the healthy women study
    Rachel H Mackey
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Am J Cardiol 90:71i-76i. 2002
    ..These results suggest that the measurement of lipoprotein subclasses may improve the prediction of CAD in postmenopausal women beyond that provided by the conventional lipid panel and CAD risk factors...
  12. ncbi request reprint Cardiovascular risk factors associated with enlarged diameter of the abdominal aortic and iliac arteries in healthy women
    Ami S Patel
    Department of Epidemiology, University of Pittsburgh, 127 Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Atherosclerosis 178:311-7. 2005
    ..Women at mid-life should continue to be targeted for weight interventions to reduce their risk for more serious cardiovascular complications...
  13. ncbi request reprint Elevated pulse wave velocity increases the odds of coronary calcification in overweight postmenopausal women
    Lakshmi Venkitachalam
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Hypertens 20:469-75. 2007
    ..Our aim is to evaluate the association between both these measures of arterial stiffness and coronary calcification (CAC), in overweight/obese postmenopausal women, without apparent cardiovascular disease...
  14. ncbi request reprint Community socioeconomic status is associated with carotid artery atherosclerosis in untreated, hypertensive men
    Karen L Petersen
    Behavioral Physiology Laboratory, Department of Psychology, University of Pittsburgh School of Medicine, 4015 O Hara Street, Pittsburgh, PA 15218, USA
    Am J Hypertens 19:560-6. 2006
    ..In this study we examined whether community SES is similarly associated with preclinical vascular disease, as measured by carotid artery ultrasonography...
  15. ncbi request reprint Lower central serotonergic responsivity is associated with preclinical carotid artery atherosclerosis
    Matthew F Muldoon
    Center for Clinical Pharmacology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Stroke 38:2228-33. 2007
    ..This investigation tested a hypothesized association between central serotonergic functioning and preclinical atherosclerosis...
  16. doi request reprint Relationship of ankle blood pressures to cardiovascular events in older adults
    Kim Sutton-Tyrrell
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, GSPH 505A Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, USA
    Stroke 39:863-9. 2008
    ..We focus on the extent to which low and high ankle-arm index values as well as noncompressible arteries are associated with mortality and cardiovascular events, including stroke in older adults...
  17. ncbi request reprint The metabolic syndrome is associated with reduced central serotonergic responsivity in healthy community volunteers
    Matthew F Muldoon
    Division of Clinical Pharmacology, Departments of Medicine and Epidemiology, University of Pittsburgh, 4015 O Hara Street, Pittsburgh, PA 15260, USA
    J Clin Endocrinol Metab 91:718-21. 2006
    ..The pathobiology of the metabolic syndrome remains unclear. The central nervous system is likely to be involved via regulation of eating, physical activity, blood pressure, and metabolism...
  18. ncbi request reprint Correlates of aortic stiffness in elderly individuals: a subgroup of the Cardiovascular Health Study
    Rachel H Mackey
    Department of Epidemiology, University of Pittsburgh, Graduate School of Public Health, PA 15261, USA
    Am J Hypertens 15:16-23. 2002
    ..Arterial stiffness has been associated with aging, hypertension, and diabetes; however, little data has been published examining risk factors associated with arterial stiffness in elderly individuals...
  19. ncbi request reprint The relationship between physical activity and lipoprotein subclasses in postmenopausal women: the influence of hormone therapy
    Kelley K Pettee
    Department of Epidemiology, Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Menopause 14:115-22. 2007
    ..This study's objective was to determine if the association between physical activity and lipids and lipoprotein subclasses in postmenopausal women varies by hormone therapy (HT) use...
  20. pmc Cardiovascular autonomic neuropathy, HDL cholesterol, and smoking correlate with arterial stiffness markers determined 18 years later in type 1 diabetes
    Catherine T Prince
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes Care 33:652-7. 2010
    ..This association persists after adjustment for potential confounders as well as for baseline HbA(1), HDL cholesterol, and smoking history, which were also associated with these PWA measures...
  21. ncbi request reprint Weight change is associated with change in arterial stiffness among healthy young adults
    Rachel P Wildman
    Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
    Hypertension 45:187-92. 2005
    ..These data greatly underscore the vascular benefit of weight loss. Successful weight loss programs in young adults, particularly blacks, are needed...
  22. ncbi request reprint Associations among walking performance, physical activity, and subclinical cardiovascular disease
    Kelley K Pettee
    Department of Exercise and Wellness, Arizona State Univerisity, Mesa, AZ 85212, USA
    Prev Cardiol 10:134-40. 2007
    ..001, respectively). Findings from the current report support the utility of the LDCW to identify women at higher risk for CVD who may be candidates for further cardiovascular testing or intensive lifestyle intervention...
  23. ncbi request reprint Alcohol consumption and lipoprotein subclasses in older adults
    Kenneth J Mukamal
    Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, RO 114, Boston, Massachusetts 02215, USA
    J Clin Endocrinol Metab 92:2559-66. 2007
    ..Limited evidence suggests that alcohol intake may be associated with lipoprotein subclass distribution, which could mediate its relationship with coronary heart disease...

Research Grants3

  1. Biochemical Heterogeneity in Morbidly Obese Women in the WHI Observational Study
    Rachel Mackey; Fiscal Year: 2007
    ..This will be the first epidemiology study to specifically focus on morbidly obesity Class III unselected for weight reduction, i.e. bariatric surgery, in black and white women. ..