Angus W MacDonald

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc Building a clinically relevant cognitive task: case study of the AX paradigm
    Angus W MacDonald
    Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
    Schizophr Bull 34:619-28. 2008
  2. ncbi request reprint Functional magnetic resonance imaging study of cognitive control in the healthy relatives of schizophrenia patients
    Angus W MacDonald
    Department of Psychology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Biol Psychiatry 60:1241-9. 2006
  3. ncbi request reprint COMT val158Met and executive control: a test of the benefit of specific deficits to translational research
    Angus W MacDonald
    Department of Psychology, University of Pittsburgh, USA
    J Abnorm Psychol 116:306-12. 2007
  4. ncbi request reprint A convergent-divergent approach to context processing, general intellectual functioning, and the genetic liability to schizophrenia
    Angus W MacDonald
    Department of Psychology, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455, USA
    Neuropsychology 19:814-21. 2005
  5. pmc What we know: findings that every theory of schizophrenia should explain
    Angus W MacDonald
    Department of Psychology, University of Minnesota, N426 Elliott Hall, 75 E River Rd, Minneapolis, MN 55455, USA
    Schizophr Bull 35:493-508. 2009
  6. ncbi request reprint Specificity of prefrontal dysfunction and context processing deficits to schizophrenia in never-medicated patients with first-episode psychosis
    Angus W MacDonald
    Department of Psychology, University of Minnesota, N219 Elliott Hall, 75 E River Rd, Minneapolis, MN 55455, USA
    Am J Psychiatry 162:475-84. 2005
  7. ncbi request reprint Event-related FMRI study of context processing in dorsolateral prefrontal cortex of patients with schizophrenia
    Angus W MacDonald
    Department of Psychology, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455, USA
    J Abnorm Psychol 112:689-97. 2003
  8. doi request reprint The legacy of "just the facts"
    Angus W MacDonald
    University of Minnesota, Department of Psychology, Minneapolis, Minnesota, USA
    Schizophr Res 131:1-3. 2011
  9. pmc Imaging genetic liability to schizophrenia: systematic review of FMRI studies of patients' nonpsychotic relatives
    Angus W MacDonald
    Department of Psychology, University of Minnesota, N218 Elliott Hall, 75 East River Road, Minneapolis, MN 55455, USA
    Schizophr Bull 35:1142-62. 2009
  10. ncbi request reprint Translational and developmental perspective on N-methyl-D-aspartate synaptic deficits in schizophrenia
    Angus W MacDonald
    Department of Psychology, University of Minnesota, Minneapolis 55455, USA
    Dev Psychopathol 18:853-76. 2006

Detail Information

Publications32

  1. pmc Building a clinically relevant cognitive task: case study of the AX paradigm
    Angus W MacDonald
    Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
    Schizophr Bull 34:619-28. 2008
    ..The development of the expectancy AX paradigm continues, and future developments that may enhance its usefulness are also described...
  2. ncbi request reprint Functional magnetic resonance imaging study of cognitive control in the healthy relatives of schizophrenia patients
    Angus W MacDonald
    Department of Psychology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Biol Psychiatry 60:1241-9. 2006
    ....
  3. ncbi request reprint COMT val158Met and executive control: a test of the benefit of specific deficits to translational research
    Angus W MacDonald
    Department of Psychology, University of Pittsburgh, USA
    J Abnorm Psychol 116:306-12. 2007
    ..These data suggest that the interpretability gained by including task manipulations to uncover specific deficits can enhance associations between cognitive and genetic levels of analysis...
  4. ncbi request reprint A convergent-divergent approach to context processing, general intellectual functioning, and the genetic liability to schizophrenia
    Angus W MacDonald
    Department of Psychology, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455, USA
    Neuropsychology 19:814-21. 2005
    ....
  5. pmc What we know: findings that every theory of schizophrenia should explain
    Angus W MacDonald
    Department of Psychology, University of Minnesota, N426 Elliott Hall, 75 E River Rd, Minneapolis, MN 55455, USA
    Schizophr Bull 35:493-508. 2009
    ....
  6. ncbi request reprint Specificity of prefrontal dysfunction and context processing deficits to schizophrenia in never-medicated patients with first-episode psychosis
    Angus W MacDonald
    Department of Psychology, University of Minnesota, N219 Elliott Hall, 75 E River Rd, Minneapolis, MN 55455, USA
    Am J Psychiatry 162:475-84. 2005
    ....
  7. ncbi request reprint Event-related FMRI study of context processing in dorsolateral prefrontal cortex of patients with schizophrenia
    Angus W MacDonald
    Department of Psychology, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455, USA
    J Abnorm Psychol 112:689-97. 2003
    ..This mechanism appeared to be impaired in patients with schizophrenia...
  8. doi request reprint The legacy of "just the facts"
    Angus W MacDonald
    University of Minnesota, Department of Psychology, Minneapolis, Minnesota, USA
    Schizophr Res 131:1-3. 2011
    ..We emphasize the importance of determining what facts are specific to the disorder - a particularly challenging endeavor - and the usefulness of various ways of quantifying these facts...
  9. pmc Imaging genetic liability to schizophrenia: systematic review of FMRI studies of patients' nonpsychotic relatives
    Angus W MacDonald
    Department of Psychology, University of Minnesota, N218 Elliott Hall, 75 East River Road, Minneapolis, MN 55455, USA
    Schizophr Bull 35:1142-62. 2009
    ....
  10. ncbi request reprint Translational and developmental perspective on N-methyl-D-aspartate synaptic deficits in schizophrenia
    Angus W MacDonald
    Department of Psychology, University of Minnesota, Minneapolis 55455, USA
    Dev Psychopathol 18:853-76. 2006
    ....
  11. ncbi request reprint A specific deficit in context processing in the unaffected siblings of patients with schizophrenia
    Angus W MacDonald
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA
    Arch Gen Psychiatry 60:57-65. 2003
    ..In the present study, we evaluated whether a specific deficit in context processing could be associated with the unexpressed genetic liability to schizophrenia...
  12. doi request reprint Prefrontal neurons transmit signals to parietal neurons that reflect executive control of cognition
    David A Crowe
    1 Department of Neuroscience, University of Minnesota, Minneapolis, Minnesota, USA 2 Brain Sciences Center, Veterans Affairs Medical Center, Minneapolis, Minnesota, USA 3 Department of Biology, Augsburg College, Minneapolis, Minnesota, USA
    Nat Neurosci 16:1484-91. 2013
    ....
  13. doi request reprint The dot pattern expectancy task: reliability and replication of deficits in schizophrenia
    Jessica A H Jones
    Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
    Psychol Assess 22:131-41. 2010
    ....
  14. pmc The neural basis of cognitive control: response selection and inhibition
    Vina M Goghari
    Translational Research in Cognitive and Affective Mechanisms Laboratory, Department of Psychology, University of Minnesota, 75 E River Road, Minneapolis, MN 55455, USA
    Brain Cogn 71:72-83. 2009
    ..This prefrontal network is recruited to a greater or lesser extent depending on specific task demands...
  15. ncbi request reprint Context-processing deficits in schizophrenia: diagnostic specificity, 4-week course, and relationships to clinical symptoms
    Deanna M Barch
    Department of Psychology, St Louis, Missouri 63130 4899, USA
    J Abnorm Psychol 112:132-43. 2003
    ..However, context-processing deficits improved in the psychotic comparison group at 4 weeks but did not improve in patients with schizophrenia...
  16. pmc Frontal hyperconnectivity related to discounting and reversal learning in cocaine subjects
    Jazmin Camchong
    Department of Psychiatry, University of Minnesota, Minneapolis, 55414, USA
    Biol Psychiatry 69:1117-23. 2011
    ..In addition, we hypothesized that abnormalities would be associated with poor performance in delayed discounting and reversal learning tasks...
  17. pmc Optimization of a goal maintenance task for use in clinical applications
    Dori Henderson
    Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
    Schizophr Bull 38:104-13. 2012
    ..These adjustments were designed to decrease administration time and/or improve reliability of the data...
  18. pmc Disrupted functional connectivity for controlled visual processing as a basis for impaired spatial working memory in schizophrenia
    Seung Suk Kang
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55455, USA
    Neuropsychologia 49:2836-47. 2011
    ....
  19. ncbi request reprint Effects of varying the experimental design of a cognitive control paradigm on behavioral and functional imaging outcome measures
    Vina M Goghari
    University of Minnesota, Twin Cities, USA
    J Cogn Neurosci 20:20-35. 2008
    ..Thus, experiments measuring successive cognitive processes may have differential detection power for every event in a trial...
  20. ncbi request reprint Sulcal thickness as a vulnerability indicator for schizophrenia
    Vina M Goghari
    Department of Psychology, University of Minnesota, N218 Elliott Hall, 75 East River Road, Minneapolis, MN 55455, USA
    Br J Psychiatry 191:229-33. 2007
    ..People with schizophrenia may demonstrate cortical abnormalities, with gyri and sulci potentially being differentially affected...
  21. ncbi request reprint Regionally specific cortical thinning and gray matter abnormalities in the healthy relatives of schizophrenia patients
    Vina M Goghari
    Department of Psychology, University of Minnesota, Twin Cities, USA
    Cereb Cortex 17:415-24. 2007
    ....
  22. doi request reprint Persecutory delusions and the perception of trustworthiness in unfamiliar faces in schizophrenia
    Kristen M Haut
    Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
    Psychiatry Res 178:456-60. 2010
    ..Such findings underscore the importance of examining symptom-specific information when studying trust in patients with schizophrenia...
  23. pmc Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: a meta-analytic review of putative endophenotypes
    Beth E Snitz
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Schizophr Bull 32:179-94. 2006
    ..Cognitive deficits, particularly those tapping such executive control functions, should continue to prove valuable as endophenotypes of interest in the search for specific genetic factors related to schizophrenia...
  24. pmc Limitations of true score variance to measure discriminating power: psychometric simulation study
    Seung Suk Kang
    Department of Psychology, Department of Psychiatry, University of Minnesota, Veterans Affairs Medical Center, Minneapolis, Minnesota, USA
    J Abnorm Psychol 119:300-6. 2010
    ..Discriminating power depends on a complicated interaction of psychometric properties that is not well estimated solely by a test's true score variance...
  25. pmc Altered functional and anatomical connectivity in schizophrenia
    Jazmin Camchong
    Department of Psychiatry, University of Minnesota, 717 Delaware Street SE, Suite 516, Minneapolis, MN 55414, USA
    Schizophr Bull 37:640-50. 2011
    ..Functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) were used to evaluate functional and anatomical brain connectivity in schizophrenia...
  26. doi request reprint Neurometrics of intrinsic connectivity networks at rest using fMRI: retest reliability and cross-validation using a meta-level method
    Krista M Wisner
    Department of Psychology, University of Minnesota, Elliott Hall, 75 East River Road, Minneapolis, MN 55455, USA
    Neuroimage 76:236-51. 2013
    ..Our findings highlight the replicability of ICNs across data sets, the range of within-subject neurometrics across different networks, and the shared characteristics between resting and task-based networks...
  27. pmc Context-processing abilities in chronic cocaine users
    Jessica A H Jones
    Department of Psychology, University of Minnesota
    Psychol Addict Behav 27:687-95. 2013
    ..Future research targeted at investigating aspects of this context-processing impairment associated with cocaine misuse can shed light on the specificity of this deficit...
  28. doi request reprint Toward a neurometric foundation for probabilistic independent component analysis of fMRI data
    Andrew B Poppe
    Department of Psychology, University of Minnesota, N426 Elliott Hall, 75 East River Road, Minneapolis, MN, 55455, USA
    Cogn Affect Behav Neurosci 13:641-59. 2013
    ..These guidelines strengthen the foundation for this data-driven approach to fMRI analysis by providing prescriptive findings and a descriptive set of neurometrics for resting-state and task fMRI...
  29. ncbi request reprint Cognitive experimental approaches to investigating impaired cognition in schizophrenia: a paradigm shift
    Angus W MacDonald
    Department of Psychiatry, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA
    J Clin Exp Neuropsychol 24:873-82. 2002
    ..We suggest that the use of these measures will increasingly become the preferred approach to the investigation of the nature, neurobiology and genetics of impaired cognition in schizophrenia in the coming years...
  30. pmc Excessive state switching underlies reversal learning deficits in cocaine users
    Edward H Patzelt
    Translational Research in Cognitive and Affective Mechanisms Laboratory, Department of Psychology, University of Minnesota, United States Department of Psychology, Harvard University, United States
    Drug Alcohol Depend 134:211-7. 2014
    ..The probabilistic reversal-learning task may be an effective way to examine dysfunction associated with cocaine addiction. However the exact nature of the performance deficits observed in cocaine users has yet to be disambiguated...
  31. doi request reprint An intrinsic connectivity network approach to insula-derived dysfunctions among cocaine users
    Krista M Wisner
    Department of Psychology, University of Minnesota, Elliott Hall, Minneapolis, MN, USA and
    Am J Drug Alcohol Abuse 39:403-13. 2013
    ..Malfunction of this integration links impulsive behavior to the insula...
  32. pmc Effects of ketamine on context-processing performance in monkeys: a new animal model of cognitive deficits in schizophrenia
    Rachael K Blackman
    1 Medical Scientist Training Program MD PhD, University of Minnesota, Minneapolis, MN, USA 2 Department of Neuroscience, University of Minnesota, Minneapolis, MN, USA 3 Brain Sciences Center, VA Medical Center, Minneapolis, MN, USA
    Neuropsychopharmacology 38:2090-100. 2013
    ....

Research Grants8

  1. The Neuroanatomical Basis of Anti-Drug Media Messages: the Impact of Effectivenes
    Angus Macdonald; Fiscal Year: 2007
    ....
  2. 5/5-Cognitive Neuroscience Task Reliability & Clinical Applications Consortium
    Angus Macdonald; Fiscal Year: 2009
    ..Thus, we need to improve our methods for detecting and enhancing cognitive function in schizophrenia in order to help individuals with this illness lead more productive and fulfilling lives. ..
  3. 5/5-Cognitive Neuroscience Task Reliability & Clinical Applications Consortium
    Angus W MacDonald; Fiscal Year: 2010
    ..Thus, we need to improve our methods for detecting and enhancing cognitive function in schizophrenia in order to help individuals with this illness lead more productive and fulfilling lives. ..
  4. 5/5-Cognitive Neuroscience Task Reliability & Clinical Applications Consortium
    Angus W MacDonald; Fiscal Year: 2010
    ..Thus, we need to improve our methods for detecting and enhancing cognitive function in schizophrenia in order to help individuals with this illness lead more productive and fulfilling lives. ..