Anna Lysakowski

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. ncbi request reprint A regional ultrastructural analysis of the cellular and synaptic architecture in the chinchilla cristae ampullares
    A Lysakowski
    Department of Anatomy and Cell Biology, University of Illinois, Chicago 60612, USA
    J Comp Neurol 389:419-43. 1997
  2. pmc Peripherin immunoreactivity labels small diameter vestibular 'bouton' afferents in rodents
    A Lysakowski
    Department of Anatomy and Cell Biology, University of Illinois at Chicago, 60612, USA
    Hear Res 133:149-54. 1999
  3. ncbi request reprint Nitric oxide synthase localized in a subpopulation of vestibular efferents with NADPH diaphorase histochemistry and nitric oxide synthase immunohistochemistry
    A Lysakowski
    Department of Anatomy and Cell Biology, University of Illinois College of Medicine, Chicago, Illinois 60612, USA
    J Comp Neurol 427:508-21. 2000
  4. pmc Molecular microdomains in a sensory terminal, the vestibular calyx ending
    Anna Lysakowski
    Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Neurosci 31:10101-14. 2011
  5. pmc Ultrastructural analysis of the cristae ampullares in the squirrel monkey (Saimiri sciureus)
    Anna Lysakowski
    Department of Anatomy and Cell Biology, University of Illinois at Chicago, Illinois 60612, USA
    J Comp Neurol 511:47-64. 2008
  6. pmc Striated organelle, a cytoskeletal structure positioned to modulate hair-cell transduction
    Florin Vranceanu
    Department of Anatomy and Cell Biology, University of Illinois, Chicago, IL 60612, USA
    Proc Natl Acad Sci U S A 109:4473-8. 2012
  7. ncbi request reprint Mechanisms of efferent-mediated responses in the turtle posterior crista
    Joseph C Holt
    Department of Neurobiology, Pharmacology, and Physiology, University of Chicago, Chicago, Illinois 60637, USA
    J Neurosci 26:13180-93. 2006
  8. pmc Quantal and nonquantal transmission in calyx-bearing fibers of the turtle posterior crista
    Joseph C Holt
    Department of Otolaryngology, University of Texas Medical Branch, Galveston, Texas, USA
    J Neurophysiol 98:1083-101. 2007
  9. pmc Alpha-9 nicotinic acetylcholine receptor immunoreactivity in the rodent vestibular labyrinth
    Anne E Luebke
    Department of Biomedical Engineering, University of Rochester School of Medicine, Rochester, New York 14642, USA
    J Comp Neurol 492:323-33. 2005
  10. ncbi request reprint M-like K+ currents in type I hair cells and calyx afferent endings of the developing rat utricle
    Karen M Hurley
    The Bobby R Alford Department of Otorhinolaryngology, Head and Neck Surgery, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 26:10253-69. 2006

Research Grants

Collaborators

  • Jay M Goldberg
  • Joseph C Holt
  • RUTH ANN EATOCK
  • Tobias Moser
  • Sapan S Desai
  • Florin Vranceanu
  • Karen M Hurley
  • Anne E Luebke
  • Guy A Perkins
  • Masako Terada
  • Robstein L Chidavaenzi
  • Mark H Ellisman
  • Sophie Gaboyard
  • Steven D Price
  • Julian R A Wooltorton
  • Meng Zhong
  • Catherine Zeh
  • Hussain Ali
  • Paul D Maroni
  • Scott M Guth

Detail Information

Publications13

  1. ncbi request reprint A regional ultrastructural analysis of the cellular and synaptic architecture in the chinchilla cristae ampullares
    A Lysakowski
    Department of Anatomy and Cell Biology, University of Illinois, Chicago 60612, USA
    J Comp Neurol 389:419-43. 1997
    ..An especially differentiated subzone may exist in the middle of the central zone...
  2. pmc Peripherin immunoreactivity labels small diameter vestibular 'bouton' afferents in rodents
    A Lysakowski
    Department of Anatomy and Cell Biology, University of Illinois at Chicago, 60612, USA
    Hear Res 133:149-54. 1999
    ..Finally, we conclude that all labelled axons and terminals were vestibular afferents rather than efferents, as no immunoreactivity in the vestibular efferent nucleus of the brainstem was observed...
  3. ncbi request reprint Nitric oxide synthase localized in a subpopulation of vestibular efferents with NADPH diaphorase histochemistry and nitric oxide synthase immunohistochemistry
    A Lysakowski
    Department of Anatomy and Cell Biology, University of Illinois College of Medicine, Chicago, Illinois 60612, USA
    J Comp Neurol 427:508-21. 2000
    ..A hypothesis about how nitric oxide is produced in the vestibular periphery and how it may interact with other elements in the vestibular sensory apparatus is presented in the discussion...
  4. pmc Molecular microdomains in a sensory terminal, the vestibular calyx ending
    Anna Lysakowski
    Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Neurosci 31:10101-14. 2011
    ..Differences in the expression and localization of proteins between afferent types and zones may contribute to known variations in afferent physiology...
  5. pmc Ultrastructural analysis of the cristae ampullares in the squirrel monkey (Saimiri sciureus)
    Anna Lysakowski
    Department of Anatomy and Cell Biology, University of Illinois at Chicago, Illinois 60612, USA
    J Comp Neurol 511:47-64. 2008
    ..Unlike cristae, type II HCs predominate in monkey maculae. Differences in hair-cell counts may reflect the stimulus magnitudes handled by semicircular canals and otolith organs...
  6. pmc Striated organelle, a cytoskeletal structure positioned to modulate hair-cell transduction
    Florin Vranceanu
    Department of Anatomy and Cell Biology, University of Illinois, Chicago, IL 60612, USA
    Proc Natl Acad Sci U S A 109:4473-8. 2012
    ....
  7. ncbi request reprint Mechanisms of efferent-mediated responses in the turtle posterior crista
    Joseph C Holt
    Department of Neurobiology, Pharmacology, and Physiology, University of Chicago, Chicago, Illinois 60637, USA
    J Neurosci 26:13180-93. 2006
    ..Ultrastructural studies, besides confirming the efferent innervation of type II hair cells and calyx endings, show that turtle efferents commonly contact afferent boutons terminating on type II hair cells...
  8. pmc Quantal and nonquantal transmission in calyx-bearing fibers of the turtle posterior crista
    Joseph C Holt
    Department of Otolaryngology, University of Texas Medical Branch, Galveston, Texas, USA
    J Neurophysiol 98:1083-101. 2007
    ..An ultrastructural study shows that inner-face inputs from type I hair cells outnumber outer-face inputs from type II hair cells by an almost 6:1 ratio...
  9. pmc Alpha-9 nicotinic acetylcholine receptor immunoreactivity in the rodent vestibular labyrinth
    Anne E Luebke
    Department of Biomedical Engineering, University of Rochester School of Medicine, Rochester, New York 14642, USA
    J Comp Neurol 492:323-33. 2005
    ..This latter response could be due to one of the other nicotinic receptors that have been described in studies from other laboratories...
  10. ncbi request reprint M-like K+ currents in type I hair cells and calyx afferent endings of the developing rat utricle
    Karen M Hurley
    The Bobby R Alford Department of Otorhinolaryngology, Head and Neck Surgery, Baylor College of Medicine, Houston, Texas 77030, USA
    J Neurosci 26:10253-69. 2006
    ..Calyx endings were strongly labeled by KCNQ4 and erg1 antisera. Thus, both hair cells and calyx endings have large M-like K+ conductances with the potential to control the gain of transmission...
  11. ncbi request reprint Comparative morphology of rodent vestibular periphery. II. Cristae ampullares
    Sapan S Desai
    Department of Anatomy and Cell Biology, University of Illinois at Chicago, M C 512 808 S Wood St, Room 578, Chicago, IL 60612, USA
    J Neurophysiol 93:267-80. 2005
    ..Apart from this eminentia cruciatum, there are no statistical differences between horizontal and vertical cristae with regard to area, width, length, the number and type of hair cells, and number of calretinin-labeled calyx afferents...
  12. ncbi request reprint Comparative morphology of rodent vestibular periphery. I. Saccular and utricular maculae
    Sapan S Desai
    Department of Anatomy and Cell Biology, University of Illinois at Chicago, M C 512 808 S Wood St, Room 578, Chicago, IL 60612, USA
    J Neurophysiol 93:251-66. 2005
    ..The function holds for species with body weights less than approximately 4 kg. Greater than 4 kg, the surface area of the sensory epithelia remains constant even with increasing body weight...
  13. ncbi request reprint Hair cell ribbon synapses
    Tobias Moser
    Department of Otolaryngology and Center for Molecular Physiology of the Brain, University of Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Cell Tissue Res 326:347-59. 2006
    ..Here, we briefly review synaptic morphology and connectivity and then focus on stimulus-secretion coupling at hair cell synapses...

Research Grants13

  1. EFFERENT INNERVATION OF IDENTIFIED VESTIBULAR AFFERENTS
    Anna Lysakowski; Fiscal Year: 2007
    ..The intent is to produce a body of morphological, neurochemical and cell biological knowledge from which physiologically and pharmacologically testable hypotheses can be derived. ..
  2. EFFERENT INNERVATION OF IDENTIFIED VESTIBULAR AFFERENTS
    Anna Lysakowski; Fiscal Year: 2004
    ..The intent is to produce a body of knowledge about the structural basis of the efferents, and their relationship to the afferents, from which physiologically and pharmacologically testable hypotheses can be derived. ..
  3. EFFERENT INNERVATION OF IDENTIFIED VESTIBULAR AFFERENTS
    Anna Lysakowski; Fiscal Year: 1999
    ..The intent is to produce a body of knowledge about the structural basis of the efferents from which physiologically and pharmacologically testable hypotheses can be derived. ..