Research Topics
| Kevin G LynchSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Publications
Moderators of response to telephone continuing care for alcoholismKevin G Lynch
Universityof Pennsylvania, 3440 Market St, Philadelphia, PA 19104, USA
Am J Health Behav 34:788-800. 2010..Continuing care was predicted to be more effective for patients with severe substance-use histories, poor initial response to treatment, and other risk factors for relapse...
Initiating acamprosate within-detoxification versus post-detoxification in the treatment of alcohol dependenceKyle M Kampman
Department of Psychiatry, University of Pennsylvania School of Medicine, 3900, Chestnut Street, Philadelphia, PA 19104, USA
Addict Behav 34:581-6. 2009..This trial compared the efficacy of acamprosate, started at the beginning of detoxification, to acamprosate started at the completion of detoxification, in the treatment of alcohol dependence...
Randomized trial of continuing care enhancements for cocaine-dependent patients following initial engagementJames R McKay
Department of Psychology, University of Pennsylvania, and Philadelphia Veterans Affairs Medical Center, Philadelphia, PA 19104, USA
J Consult Clin Psychol 78:111-20. 2010....
Extended telephone-based continuing care for alcohol dependence: 24-month outcomes and subgroup analysesJames R McKay
University of Pennsylvania, Department of Psychiatry, Philadelphia, PA 19104, USA
Addiction 106:1760-9. 2011..To determine whether 18 months of telephone continuing care improves 24-month outcomes for patients with alcohol dependence. Subgroup analyses were performed to identify patients who would benefit most from continuing care...
A double-blind, placebo-controlled trial of modafinil for cocaine dependenceCharles A Dackis
University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Subst Abuse Treat 43:303-12. 2012..06). Our negative findings might be explained by gender differences and/or inadequate psychosocial treatment intensity in patients with severe cocaine dependence...
A placebo-controlled randomized clinical trial of naltrexone in the context of different levels of psychosocial interventionDavid W Oslin
Center for the Study of Addictions, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Alcohol Clin Exp Res 32:1299-308. 2008....
A double blind, placebo-controlled trial that combines disulfiram and naltrexone for treating co-occurring cocaine and alcohol dependenceHelen M Pettinati
Center for the Study of Addictions, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Addict Behav 33:651-67. 2008..This is a double blind, placebo-controlled trial that evaluated the efficacy of disulfiram, naltrexone and their combination in patients with co-occurring cocaine and alcohol dependence...
Do patient characteristics and initial progress in treatment moderate the effectiveness of telephone-based continuing care for substance use disorders?James R McKay
University of Pennsylvania, Treatment Research Center, Philadelphia, PA 19104, USA
Addiction 100:216-26. 2005..To determine whether substance use severity, psychiatric severity, social support, self-help attendance or motivation moderated substance use outcomes in a telephone-based continuing care intervention...
A double-blind, placebo-controlled pilot trial of acamprosate for the treatment of cocaine dependenceKyle M Kampman
Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
Addict Behav 36:217-21. 2011..Therefore, we conducted a double-blind placebo-controlled pilot trial of acamprosate for the treatment of cocaine dependence...
A randomized trial of extended telephone-based continuing care for alcohol dependence: within-treatment substance use outcomesJames R McKay
Department of Psychiatry, University of Pennsylvania and Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania 19104, USA
J Consult Clin Psychol 78:912-23. 2010....
A double-blind, placebo-controlled trial of amantadine, propranolol, and their combination for the treatment of cocaine dependence in patients with severe cocaine withdrawal symptomsKyle M Kampman
Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104, USA
Drug Alcohol Depend 85:129-37. 2006..This trial evaluated the efficacy of amantadine, propranolol and their combination in cocaine dependent patients with severe cocaine withdrawal symptoms...
The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction studyTeresa R Franklin
Department of Psychiatry, University of Pennsylvania, Philadelphia School of Medicine, PA 19104, USA
Drug Alcohol Depend 103:30-6. 2009..These preliminary results demonstrate provisional evidence of the utility of baclofen to aid in smoking cessation and indicate further investigation...
Gender differences with high-dose naltrexone in patients with co-occurring cocaine and alcohol dependenceHelen M Pettinati
Department of Psychiatry, Center for the Study of Addictions, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Subst Abuse Treat 34:378-90. 2008..Thus, 150 mg/day naltrexone added to a psychosocial treatment resulted in reductions in cocaine and alcohol use and drug severity in men, compared to higher rates of cocaine and alcohol use and drug severity in women...
The effectiveness of telephone-based continuing care in the clinical management of alcohol and cocaine use disorders: 12-month outcomesJames R McKay
Department of Psychiatry, University of Pennsylvania, Treatment Research Center, 3900 Chestnut Street, Philadelphia, PA 19104, USA
J Consult Clin Psychol 72:967-79. 2004..However, in participants with alcohol dependence only (n = 91), TEL produced better alcohol use outcomes than STND on all measures examined and better outcomes than RP on some of the measures...
A double-blind, placebo-controlled pilot trial of quetiapine for the treatment of Type A and Type B alcoholismKyle M Kampman
Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Clin Psychopharmacol 27:344-51. 2007..Quetiapine is an atypical antipsychotic with a favorable side effect profile, and may be a promising medication for the treatment of alcohol dependence, particularly Type B alcoholism...
Individual characteristics of the literally homeless, marginally housed, and impoverished in a US substance abuse treatment-seeking sampleKarin M Eyrich-Garg
School of Social Administration, Dept of Public Health, Temple University College of Health Professions, Philadelphia, PA 19122, USA
Soc Psychiatry Psychiatr Epidemiol 43:831-42. 2008....
Initial reliability and validity studies of the revised Treatment Services Review (TSR-6)John S Cacciola
University of Pennsylvania Center for Studies of Addiction, Philadelphia, PA 19104, USA The Treatment Research Institute, Philadelphia, PA 19106, USA
Drug Alcohol Depend 92:37-47. 2008..Report the results of initial reliability and validity analyses for a revised Treatment Services Review (TSR-6) instrument which measures a broader range of services than the original TSR...
Study blinding and correlations between perceived group assignment and outcome in a cocaine pharmacotherapy trialCatharine E Fairbairn
Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Am J Addict 17:387-91. 2008..Furthermore, nurses' perceptions of treatment assignment were significantly related to trial completion, medication compliance, and cocaine use--results that may have training implications for medical personnel...
Elevated substance P levels in HIV-infected women in comparison to HIV-negative womenSteven D Douglas
Division of Allergy and Immunology, Department of Pediatrics, Joseph Stokes Jr Research Institute at The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
AIDS Res Hum Retroviruses 24:375-8. 2008..We now demonstrate that substance P plasma levels are significantly higher in HIV-infected women in comparison to uninfected control women...
Examining naltrexone and alcohol effects in a minority population: results from an initial human laboratory studyJennifer G Plebani
Department of Psychiatry, University of Pennsylvania, Philadelphia, 19104, USA
Am J Addict 20:330-6. 2011..Future studies should investigate African-American populations with heavy drinking as well as alcohol-dependent subjects in order to strengthen the parallels to clinical findings...
Results of an initial clinical trial of varenicline for the treatment of cocaine dependenceJennifer G Plebani
University of Pennsylvania, Department of Psychiatry, Treatment Research Center, 3900 Chestnut Street, Philadelphia, PA 19104, United States plebani
Drug Alcohol Depend 121:163-6. 2012..Cocaine use, abuse and dependence remains a pressing public health problem. Based on its mechanism of action, varenicline, an alpha4beta2 partial agonist seemed to be a likely candidate for treating cocaine dependence...
Reliability and validity of the alcohol short index of problems and a newly constructed drug short index of problemsArthur I Alterman
Center for Studies of Addiction, University of Pennsylvania, 3440 Market Street, Suite 370, Philadelphia, Pennsylvania 19104, USA
J Stud Alcohol Drugs 70:304-7. 2009....
Early abstinence in cocaine pharmacotherapy trials predicts successful treatment outcomesJennifer G Plebani
Department of Psychiatry, University of Pennsylvania, Treatment Research Center, 3900 Chestnut Street, Philadelphia, PA 19104, USA
J Subst Abuse Treat 37:313-7. 2009..This finding has implications both for treatment research and for clinical practice, suggesting that patients who do not respond early in treatment may need a more intensive intervention...
Prescription OxyContin abuse among patients entering addiction treatmentDeni Carise
Treatment Systems Section, Treatment Research Institute, 600 Public Ledger Building, 150 South Independence Mall West, Philadelphia, PA 19106 3475, USA
Am J Psychiatry 164:1750-6. 2007..The purpose of this study was to characterize the nature and origins of pharmaceutical opioid addiction among patients presenting at substance abuse treatment programs...
Menstrual cycle phase at quit date predicts smoking status in an NRT treatment trial: a retrospective analysisTeresa R Franklin
Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6178, USA
J Womens Health (Larchmt) 17:287-92. 2008..However, no experimental data have been published to support this claim. Our objective was to determine whether MC phase affected smoking status in premenopausal female smokers participating in a smoking cessation treatment trial...
A randomized, controlled study of treatment for alcohol dependence in patients awaiting liver transplantationRobert M Weinrieb
Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Liver Transpl 17:539-47. 2011..Further research to validate our findings or to identify better methods to identify and intervene with patients at risk of pretransplant and posttransplant drinking should continue...
Does mandating offenders to treatment improve completion rates?Donna M Coviello
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
J Subst Abuse Treat 44:417-25. 2013..9, CI=2.0-59.1, p=.006). These findings demonstrate that stipulated treatment for offenders may be an effective way to increase treatment compliance...
Identifying risk factors for marijuana use among veterans affairs patientsMarina Goldman
Department of Psychiatry MG, JJS, KL, RS, HX, CPO, DWO, University of Pennsylvania School of Medicine, Philadelphia, PA and Philadelphia Veterans Affairs Medical Center VAMC Philadelphia JJS, Jr, CPO, DWO and VISN 4 Mental Illness Research, Education and Clinical Center MIRECC, Philadelphia, PA
J Addict Med 4:47-51. 2010..If data commonly collected in the primary care setting (eg, use of alcohol, smoking status, and depression symptoms) could predict cannabis use, then providers can implement targeted marijuana screening in high-risk groups...
Addiction Severity Index Recent and Lifetime summary indexes based on nonparametric item response theory methodsArthur I Alterman
Department of Psychiatry, University of Pennsylvania School of Medicine, PA, USA
Psychol Assess 19:119-32. 2007..NIRT-based methods were able to add to findings produced previously by classical psychometric methods and appear to offer promise for the psychometric analysis of complex, mixed-format instruments such as the ASI-5...
Conceptual, methodological, and analytical issues in the study of relapseJames R McKay
University of Pennsylvania, Treatment Research Center, Philadelphia 19104, USA
Clin Psychol Rev 26:109-27. 2006..Nevertheless, important methodological advances have been and continue to be made in the study of relapse, and our knowledge about the nature and process of relapse has increased considerably over the past 10 years...
Family functioning and peer affiliation in children of fathers with antisocial personality disorder and substance dependence: associations with problem behaviorsHoward B Moss
Center for Education and Drug Abuse Research, University of Pittsburgh and St Francis Medical Center, Pittsburgh, PA, USA
Am J Psychiatry 159:607-14. 2002..The authors examined associations between the child's psychopathology, paternal substance dependence/antisocial personality disorder status, and measures of family and peer environments...
The effectiveness of telephone-based continuing care for alcohol and cocaine dependence: 24-month outcomesJames R McKay
Department of Psychiatry, University of Pennsylvania, Philadelphia 19104, USA
Arch Gen Psychiatry 62:199-207. 2005....
Carbohydrate-deficient transferrin levels reflect heavy drinking in alcohol-dependent women seeking treatmentMargaret R Rukstalis
Center for the Study of Addictions, Department of Psychiatry, University of Pennsylvania, and Philadelphia Medical Center for Veteran Affairs, Philadelphia Pennsylvania 19104, USA
Alcohol Clin Exp Res 26:1539-44. 2002..The study also examined the extent that E2 levels mediated the relationship between CDT levels and heavy drinking in the alcohol-dependent women...
Modafinil and cocaine: a double-blind, placebo-controlled drug interaction studyCharles A Dackis
Department of Psychiatry, University of Pennsylvania, 3900 Chestnut Street, Philadelphia, PA 19104, USA
Drug Alcohol Depend 70:29-37. 2003..Furthermore, pretreatment with modafinil did not intensify cocaine euphoria or cocaine-induced craving. In fact, cocaine euphoria was significantly blunted (P=0.02) in one of our subjective measures...
Can we design and replicate clinical trials with a multiple drug focusKevin G Lynch
Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia 19104-6178, USA
Drug Alcohol Depend 70:135-7. 2003
A pilot trial of olanzapine for the treatment of cocaine dependenceKyle M Kampman
Department of Psychiatry, School of Medicine, Treatment Research Center, University of Pennsylvania, 3900 Chestnut Street, Philadelphia, PA 19104, USA
Drug Alcohol Depend 70:265-73. 2003....
Affiliation with deviant peers among children of substance dependent fathers from pre-adolescence into adolescence: associations with problem behaviorsHoward B Moss
Treatment Research Center, University of Pennsylvania, 3900 Chestnut Street, Philadelphia, PA 19104, USA
Drug Alcohol Depend 71:117-25. 2003..However, little data are available concerning the developmental trajectories of deviant peer affiliation...
Accumbal neural responses during the initiation and maintenance of intravenous cocaine self-administrationLaura L Peoples
Department of Psychology, University of Pennsylvania, Philadelphia 19104, USA
J Neurophysiol 91:314-23. 2004..Finally, the data have potential implications for understanding mechanisms that transduce accumbal-mediated drug effects that contribute to drug addiction...
A critical review of selective serotonin reuptake inhibitor-associated bleeding: balancing the risk of treating hepatitis C-infected patientsRobert M Weinrieb
Department of Psychiatry, University of Pennsylvania, Philadelphia, USA
J Clin Psychiatry 64:1502-10. 2003..Because there is an increased risk of bleeding in HCV-infected patients who have developed cirrhosis and either portal hypertension or hepatic failure or both, we critically reviewed the literature on SSRI-associated bleeding...
Adding a nicotine blocking agent to cigarette taperingPeter Gariti
Treatment Research Center, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J Subst Abuse Treat 27:17-25. 2004..Biochemically confirmed abstinence rates at followups did not differ between treatment groups (AD&C = 10%, 13%, 10% vs. PD&C = 3%, 10%, 13%). There is not enough evidence to suggest a Stage II trial...
A randomized trial of oral naltrexone for treating opioid-dependent offendersDonna M Coviello
Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA coviello
Am J Addict 19:422-32. 2010..The study provides limited support for the use of oral naltrexone for offenders who are not closely monitored by the criminal justice system...
A double-blind, placebo-controlled trial of modafinil for cocaine dependenceCharles A Dackis
University of Pennsylvania School of Medicine, Philadelphia 19104, USA
Neuropsychopharmacology 30:205-11. 2005..This study provides preliminary evidence, which should be confirmed by a larger study, that modafinil improves clinical outcome when combined with psychosocial treatment for cocaine dependence...
Selective serotonin reuptake inhibitor and substance P antagonist enhancement of natural killer cell innate immunity in human immunodeficiency virus/acquired immunodeficiency syndromeDwight L Evans
Department of Psychiatry, Joseph J Stokes Research Institute of The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Biol Psychiatry 63:899-905. 2008..This study examines the potential role of three underlying regulatory systems that have been under investigation in central nervous system research as well as immune and viral research: serotonin, neurokinin, and glucocorticoid systems...
Extended vs short-term buprenorphine-naloxone for treatment of opioid-addicted youth: a randomized trialGeorge E Woody
Department of Psychiatry, Treatment Research Institute, University of Pennsylvania, 150 S Independence Mall W, Ste 600, Philadelphia, PA 19106, USA
JAMA 300:2003-11. 2008..The usual treatment for opioid-addicted youth is detoxification and counseling. Extended medication-assisted therapy may be more helpful...
Selective strengthening of conditioned behaviors that occur during periods of amphetamine exposureXun Wan
Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA
Neuropsychopharmacology 32:1346-57. 2007..These findings are relevant to hypotheses regarding the etiology of drug addiction...
An examination of potential sex and race effects in a study of continuing care for alcohol- and cocaine-dependent patientsJames R McKay
Treatment Research Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6178, USA
Alcohol Clin Exp Res 27:1321-3. 2003
Characteristics and 9-month outcomes of discharged methadone maintenance clientsDonna M Coviello
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
J Subst Abuse Treat 40:165-74. 2011..Despite having more severe problems, the Tx group had fewer opioid-positive urines and reported less IV drug use at 9 months postdischarge compared to the NoTx group. The findings highlight the importance of rapid treatment reengagement...
Treatment outcomes in type A and B alcohol dependence 6 months after serotonergic pharmacotherapyWilliam Dundon
Center for the Studies of Addiction, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6178, USA
Alcohol Clin Exp Res 28:1065-73. 2004..The purpose of this study was to assess in this original study group whether treatment gains in the type A alcoholics were maintained or whether treatment outcomes changed for the type B alcoholics after discontinuing pharmacotherapy...
Sexual and physical victimization as predictors of HIV risk among felony drug offendersSteven Belenko
Treatment Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania 19106 3475, USA
AIDS Behav 9:311-23. 2005..Assessing for specific prior abuse histories of offenders and providing targeted interventions may be useful for developing more effective primary and secondary HIV prevention services for this high-risk population...
Effects of an intensive street-level police intervention on syringe exchange program use in Philadelphia, PACorey S Davis
BS, University of Pennsylvania, Center for the Study of Addiction, HIV AIDS Prevention Research Division, 3535 Market Street, Suite 4058, Philadelphia, PA 19104 3309, USA
Am J Public Health 95:233-6. 2005..Declines in use among Black and male participants were much more pronounced than decreases among White and female participants...
Initial evidence for the reliability and validity of a "Lite" version of the Addiction Severity IndexJohn S Cacciola
University of Pennsylvania Center for Studies of Addiction, 3440 Market Street, Philadelphia, PA 19104, USA
Drug Alcohol Depend 87:297-302. 2007..To evaluate the psychometric properties of a shortened version of the baseline ASI-5, the ASI-L-VA...
Accumbal neurons that are activated during cocaine self-administration are spared from inhibitory effects of repeated cocaine self-administrationLaura L Peoples
Department of Psychology, University of Pennsylvania, Philadelphia, PA 19106, USA
Neuropsychopharmacology 32:1141-58. 2007..The findings of the present study are consistent with a basic prediction of the differential inhibition hypothesis and may be relevant to understanding cocaine addiction...
A multisite pilot study of extended-release injectable naltrexone treatment for previously opioid-dependent parolees and probationersDonna M Coviello
University of Pennsylvania, Philadelphia, Pennsylvania, USA coviello
Subst Abus 33:48-59. 2012..The findings indicate that XR-NTX holds promise as a feasible, effective treatment option for opioid-dependent offenders...
Naltrexone reduces the relative reinforcing value of nicotine in a cigarette smoking choice paradigmMargaret Rukstalis
Tobacco Use Research Center, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA
Psychopharmacology (Berl) 180:41-8. 2005..Naltrexone and bupropion have been shown to alter ad lib smoking behavior; however, medication effects on nicotine reward in a cigarette choice paradigm have yet to be investigated...
Selective serotonin re-uptake inhibitors and the risk of bleedingRobert M Weinrieb
University of Pennsylvania, Department of Psychiatry, 3440 Market Street, Suite 370, Philadelphia, PA 19104, USA
Expert Opin Drug Saf 4:337-44. 2005..Clinicians should caution patients about combining SSRIs with aspirin or NSAIDs. Pharmacotherapy to reduce the risk of GI bleeding should be considered in high risk patients...
A pilot trial of topiramate for the treatment of cocaine dependenceKyle M Kampman
Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104, USA
Drug Alcohol Depend 75:233-40. 2004..Topiramate, an anticonvulsant, raises cerebral GABA levels, facilitates GABAergic neurotransmission and inhibits glutametergic activity at AMPA/kainite receptors. Thus, it may be useful for treating cocaine dependence...
Causal mediation analyses with rank preserving modelsThomas R Ten Have
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Biometrics 63:926-34. 2007..The trade-off between these assumptions is evaluated in the context of two suicide/depression intervention studies...
Rapid relapse generally follows treatment for substance use disorders among adolescentsJack R Cornelius
Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Addict Behav 28:381-6. 2003..1993). In J. S. Baer, G. A. Marlatt, & R. J. McMahon (Eds.), Addictive behaviors across the life span (pp. 160-183). London: SAGE.] in showing that most adolescents relapse quickly following treatment for substance use disorders...
Physical and sexual abuse, depression and alcohol use disorders in adolescents: onsets and outcomesDuncan B Clark
Department of Psychiatry and Pharmaceutical Sciences, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Drug Alcohol Depend 69:51-60. 2003..These results indicate that MDD among adolescents with AUD may be partly attributable to PS Abuse...
Psychiatric and substance use disorders as risk factors for attempted suicide among adolescents: a case control studyThomas M Kelly
Western Psychiatric Institute and Clinic, Pittsburgh Adolescent Alcohol Research Center, University of Pittsburgh Medical School, PA 15213, USA
Suicide Life Threat Behav 32:301-12. 2002..Evaluation of these particular comorbid conditions should be part of the adolescent suicide risk assessment...
A matched comparison study of medical and psychiatric complications and anesthesia and analgesia requirements in methadone-maintained liver transplant recipientsRobert M Weinrieb
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA
Liver Transpl 10:97-106. 2004..Posttransplant, 20% of patients receiving MMT used alcohol or illicit drugs. Data do not support withholding the provision of liver transplantation to patients receiving MMT, but larger, well-controlled studies are warranted...
Multidimensional assessment of nicotine dependence in adolescentsDuncan B Clark
Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Drug Alcohol Depend 77:235-42. 2005..The findings suggest that the NDSS has acceptable psychometric properties when applied to adolescents, complementing smoking rate and FTND in a multidimensional smoking assessment...
Attention-deficit/hyperactivity disorder and conduct disorder symptomatology in adolescents with alcohol use disorderBrooke S G Molina
Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
Psychol Addict Behav 16:161-4. 2002..The findings did not differ between boys and girls, revealing that in a treatment sample of adolescents, ADHD-CD comorbidity may need to be assessed and treated, but it is not broadly indicative of severity...
Mediators of telephone-based continuing care for alcohol and cocaine dependenceJanell Lynn Mensinger
Clinical Research Unit, Reading Hospital and Medical Center, Reading, PA 19612 6052, USA
J Consult Clin Psychol 75:775-84. 2007..These results are consistent with a model in which treatment effects are first accounted for by changes in behavior, followed by changes in self-efficacy and in commitment to abstinence...
Genetic correlations between smoking initiation and smoking behaviors in a twin sampleThomas L Hardie
University of Delaware, Department of Nursing, Rm 361 McDowell Hall, Newark, DE 19716, USA
Addict Behav 31:2030-7. 2006..The interventional implications of the findings support the importance of a tailored approach to preventing smoking behavior and reducing harm in smokers...
Racial disparities in hospitalized elderly patients with chronic heart failureErlinda C Wheeler
Department of Nursing, University of Delaware, Newark, USA
J Transcult Nurs 15:291-7. 2004..65, p =.000; and total charges F(3, 99,543) = 38,962.95, p =.000. LOS accounted for 50% of the variance. Studies that examine cultural variables and their effect on LOS and number of procedures are needed...
Childhood abuse as a risk factor for suicidal behavior in borderline personality disorderPaul H Soloff
Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh, USA
J Pers Disord 16:201-14. 2002..Given a history of childhood sexual abuse, the risk of adult suicidal behavior in BPD was increased by antisocial traits, severity of BPD, hopelessness, or comorbid major depressive episode (MDE)...
Developing adaptive treatment strategies in substance abuse researchSusan A Murphy
University of Michigan, Institute for Social Research, Ann Arbor, MI 48106 1248, USA
Drug Alcohol Depend 88:S24-30. 2007..Simple analyses that can be used with the SMART design are described. Furthermore, the SMART design is compared with standard experimental designs...
The availability of web sites offering to sell opioid medications without prescriptionsRobert F Forman
Medical Affairs Alkermes, Inc, 88 Sidney St, Cambridge, MA 02139, USA
Am J Psychiatry 163:1233-8. 2006..This study was designed to determine the availability of web sites offering to sell opioid medications without prescriptions...
Acceptability of audio computer-assisted self-interview (ACASI) among substance abusers seeking treatment in Rio de Janeiro, BrazilAnna Azevedo Simoes
Health Department of the State Government of Rio de Janeiro, Brazil
Drug Alcohol Depend 82:S103-7. 2006..The findings extend our understanding of the role of the ACASI method by suggesting the utility of this approach in assessing HIV risk among low-to middle-income drug users in a cultural setting quite different from previous studies...
Alcohol relapse as a function of relapse definition in a clinical sample of adolescentsStephen A Maisto
Department of Psychology, Syracuse University, 430 Huntington Hall, Syracuse, NY 13244, USA
Addict Behav 28:449-59. 2003..Suggestions for the extensions of this investigation in future research are provided...
Treatment services received in the CASAWORKS for Families programJames R McKay
Treatment Research Institute, University of Pennsylvania, USA
Eval Rev 27:629-55. 2003..Longer retention was associated with better alcohol use outcomes but was unrelated to employment or drug use outcomes...
A randomized trial of audio computer and in-person interview to assess HIV risk among drug and alcohol users in Rio De Janeiro, BrazilAnna Azevedo Simoes
Health Department of the State Government of Rio de Janeiro, Rio de Janeiro, Brazil
J Subst Abuse Treat 30:237-43. 2006..ACASI seems to be a key resource in improving the reporting of sensitive data in Brazil, as it has been in prior international studies...
The relationship between alcohol and individual differences variables on attitudes and behavioral skills relevant to sexual health among heterosexual young adult menStephen A Maisto
Department of Psychology and Center for Health and Behavior, Syracuse University, 430 Huntington Hall, Syracuse, New York 13244, USA
Arch Sex Behav 33:571-84. 2004....
Research Grants
- Mediation methods in alcohol continuing care researchKevin Lynch; Fiscal Year: 2007..This study investigates the performance of new statistical methods for mediation, where a more explicit causal interpretation off mediation may be possible. We compare these methods with standard approaches. ..
