Robert H Lustig
Affiliation: University of California
- Pediatric endocrine disorders of energy balanceRobert H Lustig
Division of Endocrinology, University of California San Francisco, 94143, USA
Rev Endocr Metab Disord 6:245-60. 2005
- The 'skinny' on childhood obesity: how our western environment starves kids' brainsRobert H Lustig
Division of Endocrinology, University of California at San Francisco Center for Obesity Assessment, Study and Ttreatment, 94143 0434, USA
Pediatr Ann 35:898-902, 905-7. 2006..This will require a grassroots, bottom-up effort on the part of parents and community leaders. We as pediatricians must lead the way...
- Fructose: metabolic, hedonic, and societal parallels with ethanolRobert H Lustig
Division of Endocrinology, University of California, San Francisco, CA 94143 0434, USA
J Am Diet Assoc 110:1307-21. 2010..On a societal level, the treatment of fructose as a commodity exhibits market similarities to ethanol. Analogous to ethanol, societal efforts to reduce fructose consumption will likely be necessary to combat the obesity epidemic...
- Efficacy of a child-centred and family-based program in promoting healthy weight and healthy behaviors in Chinese American children: a randomized controlled studyJyu Lin Chen
Department of Family Health Care Nursing, University of California, San Francisco, CA, USA
J Public Health (Oxf) 32:219-29. 2010..To examine the efficacy of an interactive, child-centred and family-based program in promoting healthy weight and healthy lifestyles in Chinese American children...
- Adolescent obesity and puberty: the "perfect storm"Carolyn Bradner Jasik
Department of Pediatrics, School of Medicine, University of California, San Francisco, San Francisco, CA 94143 0503, USA
Ann N Y Acad Sci 1135:265-79. 2008..Therefore, intervening prior to pubertal onset becomes even more important given the risk factors present once puberty begins...
- A clinic-based lifestyle intervention for pediatric obesity: efficacy and behavioral and biochemical predictors of responseKristine A Madsen
Department Pediatrics, University of California, San Francisco, CA 94118, USA
J Pediatr Endocrinol Metab 22:805-14. 2009..To examine efficacy and predictors of response to a lifestyle intervention for obese youth...
- Pituitary development and physiologyCLEMENT C CHEUNG
Department of Pediatrics, University of California, San Francisco, CA 94142, USA
Pituitary 10:335-50. 2007..This review concludes with a discussion of several of these genes and the genetic disorders with which they are associated...
- The Active Balance Childhood program for improving coping and quality of life in Chinese American childrenJyu Lin Chen
Department of Family Health Care Nursing, School of Nursing, University of California, San Francisco, CA 94143, USA
Nurs Res 59:270-9. 2010..However, few studies have examined whether an intervention that teaches coping strategies in weight management can influence children's coping behavior and psychosocial well-being...
- Insulin dynamics predict body mass index and z-score response to insulin suppression or sensitization pharmacotherapy in obese childrenRobert H Lustig
Division of Pediatric Endocrinology, Department of Pediatrics, University of California, San Francisco, USA
J Pediatr 148:23-9. 2006....
- Childhood obesity: adrift in the "limbic triangle"Michele L Mietus-Snyder
Department of Pediatrics, University of California, San Francisco, California 94143, USA
Annu Rev Med 59:147-62. 2008..quot; Integrated multidisciplinary family- and community-based education, effective stress reduction, and a societal commitment to alter the food and built environments are all necessary components to battle the global obesity epidemic...
- Octreotide therapy of pediatric hypothalamic obesity: a double-blind, placebo-controlled trialRobert H Lustig
Department of Endocrinology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
J Clin Endocrinol Metab 88:2586-92. 2003..Octreotide suppressed insulin, and stabilized weight and BMI. Improved quality of life correlated with the degree of insulin suppression. Octreotide was safe and well tolerated...
- Risk factors for the development of obesity in children surviving brain tumorsRobert H Lustig
Departments of Endocrinology, St Jude Children s Research Hospital, Memphis, Tennessee 38105, USA
J Clin Endocrinol Metab 88:611-6. 2003....
- Optimizing growth hormone efficacy: an evidence-based analysisRobert H Lustig
Division of Endocrinology, Department of Pediatrics, University of California, San Francisco, CA 94143 0434, USA
Horm Res 62:93-7. 2004..e. increments in IGF-I level have not been shown to correlate with increments in height velocity. Thus, these issues with respect to achievement of final height are far from solved...
- Autonomic dysfunction of the beta-cell and the pathogenesis of obesityRobert H Lustig
Division of Endocrinology, University of California, San Francisco, CA 94143-0136, USA
Rev Endocr Metab Disord 4:23-32. 2003
- Childhood obesity: behavioral aberration or biochemical drive? Reinterpreting the First Law of ThermodynamicsRobert H Lustig
Division of Endocrinology, University of California San Francisco, San Francisco, CA 94143 0434, USA
Nat Clin Pract Endocrinol Metab 2:447-58. 2006..This weight gain is driven by the hyperinsulinemic state, through three mechanisms: energy partitioning into adipose tissue; interference with leptin signal transduction; and interference with extinction of the hedonic response to food...
- Sugar-sweetened beverages, serum uric acid, and blood pressure in adolescentsStephanie Nguyen
Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA
J Pediatr 154:807-13. 2009..To evaluate whether sugar-sweetened beverage consumption, a significant source of dietary fructose, is associated with higher serum uric acid levels and blood pressure in adolescents...
- Hypothalamic obesity: causes, consequences, treatmentRobert H Lustig
Division of Endocrinology, University of California San Francisco, CA 94143 0434, USA
Pediatr Endocrinol Rev 6:220-7. 2008..Recently, bariatric surgery (Roux-en-Y gastric bypass, laparoscopic gastric banding, vagotomy) have also been attempted with variable results. Early and intensive management is required to stave off the obesity and its consequences...
- Outpatient transition of an infant with permanent neonatal diabetes due to a KCNJ11 activating mutation from subcutaneous insulin to oral glyburideAndrew A Bremer
Division of Endocrinology, Department of Pediatrics, University of California Davis Medical Center, Sacramento, CA 95817 2208, USA
Pediatr Diabetes 9:236-9. 2008..We describe a case of an 18-month-old infant with permanent neonatal diabetes due to an activating KCNJ11 mutation successfully transitioned from subcutaneous insulin therapy to oral sulfonylurea therapy in the outpatient setting...
- Fast food, central nervous system insulin resistance, and obesityElvira Isganaitis
Department of Pediatrics, University of California, San Francisco, CA 94143-0434, USA
Arterioscler Thromb Vasc Biol 25:2451-62. 2005..Finally, we analyze the characteristics of fast food, including high-energy density, high fat, high fructose, low fiber, and low dairy intake, which favor the development of CNS insulin resistance and obesity...
- Racial and etiopathologic dichotomies in insulin hypersecretion and resistance in obese childrenChaluntorn Preeyasombat
Department of Pediatrics, University of California-San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143-0434, USA
J Pediatr 146:474-81. 2005..CONCLUSIONS: Insulin hypersecretion and resistance are distinct phenomena in childhood obesity. Insulin hypersecretion appears to be the more relevant insulin abnormality both in obese blacks and in CNS insult...
- Racial disparity in glucagon-like peptide 1 and inflammation markers among severely obese adolescentsPedro A Velasquez-Mieyer
Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Diabetes Care 31:770-5. 2008....
- Which comes first? The obesity or the insulin? The behavior or the biochemistry?Robert H Lustig
J Pediatr 152:601-2. 2008
- Radiation dose-volume effects on growth hormone secretionThomas E Merchant
Department of Radiation Oncology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Int J Radiat Oncol Biol Phys 52:1264-70. 2002..Conformal radiotherapy (CRT) techniques allow for a more accurate determination of hypothalamic dosimetry. We correlated the dosimetry of the hypothalamus and the peak GH value after CRT in children with localized primary brain tumors...
- Preirradiation endocrinopathies in pediatric brain tumor patients determined by dynamic tests of endocrine functionThomas E Merchant
Department of Radiation Oncology, St Jude Children s Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA
Int J Radiat Oncol Biol Phys 54:45-50. 2002..To prospectively evaluate pediatric patients with localized primary brain tumors for evidence of endocrinopathy before radiotherapy (RT)...
- Use of somatostatin receptor ligands in obesity and diabetic complicationsBernhard O Boehm
Division of Endocrinology, Ulm University, Robert-Koch-Strasse 8, Ulm/Donau, 89070, Germany
Best Pract Res Clin Gastroenterol 16:493-509. 2002..The use of somatostatin analogues addressing the various hormonal imbalances of these disorders may provide a novel concept for their pharmacological treatment...
- Craniopharyngioma: the St. Jude Children's Research Hospital experience 1984-2001Thomas E Merchant
Department of Radiation Oncology, St Jude Children s Research Hospital, 332 N Lauderdale Street, Memphis, TN 38105 2794, USA
Int J Radiat Oncol Biol Phys 53:533-42. 2002..To review our institution's experience in the treatment of craniopharyngioma and assess the merits of initial therapy with limited surgery and irradiation...
- Television viewing and hypertension in obese childrenPerrie E Pardee
Department of Pediatrics, School of Medicine, University of California, Rady Children s Hospital and Health Center, San Diego 92103 845, USA
Am J Prev Med 33:439-43. 2007..However, the association between TV viewing and hypertension in children is unknown. This study aimed to identify whether TV watching is associated with hypertension in obese children...
- Hypothalamic dysfunction after chemotherapySusan R Rose
Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA
J Pediatr Endocrinol Metab 17:55-66. 2004....
- Preliminary results from a phase II trial of conformal radiation therapy and evaluation of radiation-related CNS effects for pediatric patients with localized ependymomaThomas E Merchant
Department of Biostatistics, St Jude Children s Research Hospital, 332 N Lauderdale St, Memphis, TN 38105 2794, USA
J Clin Oncol 22:3156-62. 2004....
- ACTH deficiency in childhood cancer survivorsSusan R Rose
Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Pediatr Blood Cancer 45:808-13. 2005..Adrenocorticotropin deficiency (ACTHD) can be clinically subtle, but life-threatening if not recognized. We assessed the prevalence of ACTHD in survivors of childhood cancer according to tumor diagnosis/therapy...
- Childhood obesityPhyllis W Speiser
Division of Pediatric Endocrinology, Schneider Children s Hospital, 269 01 76th Avenue, New Hyde Park, New York 11040, USA
J Clin Endocrinol Metab 90:1871-87. 2005..In developing a consensus statement, this international group has presented the evidence, developed recommendations, and provided a platform aimed toward future corrective action and ongoing debate in the international community...