Research Topics
Genomes and Genes | Lawrence R LustigSummaryAffiliation: University of California Country: USA Publications
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Publications
Cochlear gene therapyLawrence R Lustig
Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, San Francisco, California 94115, USA
Curr Opin Neurol 25:57-60. 2012....
Nicotinic acetylcholine receptor structure and function in the efferent auditory systemLawrence R Lustig
Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, California 941430, USA
Anat Rec A Discov Mol Cell Evol Biol 288:424-34. 2006....- Anesthesia, antisepsis, microscope: the confluence of neurotologyLawrence R Lustig
Division of Otology, Neurotology, and Skull Base Surgery, Department of Otolaryngology Head and Neck Surgery, University of California, 400 Parnassus Avenue, Suite ACC 746, San Francisco, CA 94143 0342, USA
Otolaryngol Clin North Am 40:415-37, vii. 2007..This historical overview focuses upon the origins of the specialty, from the birth of otology and neurosurgery up through the last quarter century... - Chondrosarcomas of the skull base and temporal boneL R Lustig
Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, California 94143 0342, USA
J Laryngol Otol 121:725-35. 2007..To evaluate the clinical presentation and outcomes of treatment for patients with chondrosarcomas involving the skull base and temporal bone... - Cochlear implantation in patients with neurofibromatosis type 2 and bilateral vestibular schwannomaLawrence R Lustig
Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University, Baltimore, Maryland, and Department of Otolaryngology Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA
Otol Neurotol 27:512-8. 2006..To investigate the results of cochlear implantation in patients with neurofibromatosis Type 2 (NF2) and bilateral vestibular schwannoma... - The history of intratympanic drug therapy in otologyLawrence R Lustig
Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, 400 Parnassus Avenue, Suite ACC 746, San Francisco, CA 94143 0342, USA
Otolaryngol Clin North Am 37:1001-17. 2004..This article presents the development of intratympanic drug therapy from early times through the nineteenth century... - Progressive deafness and altered cochlear innervation in knock-out mice lacking prosaposinOmar Akil
Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, San Francisco, California 94143 0449, USA
J Neurosci 26:13076-88. 2006..Furthermore, prosaposin's overlapping developmental expression pattern and binding capacity toward the nAChR alpha10 suggest that alpha10 may also play a role in this function... 
Restoration of hearing in the VGLUT3 knockout mouse using virally mediated gene therapyOmar Akil
Department of Otolaryngology, Head and Neck Surgery, University of California San Francisco, San Francisco, CA 94143, USA
Neuron 75:283-93. 2012..These findings represent a successful restoration of hearing by gene replacement in mice, which is a significant advance toward gene therapy of human deafness...- Cochlear implantation in patients with bilateral Ménière's syndromeLawrence R Lustig
Department of Otolaryngology, Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland 21287, USA
Otol Neurotol 24:397-403. 2003..To evaluate the indications and clinical outcomes (audiologic and vestibular) in patients with Ménière's syndrome who have undergone cochlear implantation... - Sir Charles Alfred Ballance: contributions to otology and neurotologyErik H Waldman
Department of Otolaryngology, Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Otol Neurotol 26:1073-82. 2005..This work focuses on the otologic and neurotologic endeavors of Sir Charles Alfred Ballance, bringing his accomplishments into modern relief... - Dehiscence of bone overlying the superior canal as a cause of apparent conductive hearing lossLloyd B Minor
Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Otol Neurotol 24:270-8. 2003..To identify patients with superior semicircular canal dehiscence and apparent conductive hearing loss and to define the cause of the air-bone gap... - Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3Rebecca P Seal
Department of Physiology, School of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
Neuron 57:263-75. 2008..The glutamate release conferred by expression of VGLUT3 thus has an essential role in both function and development of the auditory pathway, as well as in the control of cortical excitability... - Role of the copper transporter, CTR1, in platinum-induced ototoxicitySwati S More
Departments of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California 94143 0449, USA
J Neurosci 30:9500-9. 2010..The possibility of local administration of CTR1 inhibitors during cisplatin therapy as a means of otoprotection is thereby raised... - External magnet displacement in cochlear implants: causes and managementDavid Posner
Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, San Francisco, California 94143 0342, USA
Otol Neurotol 31:88-93. 2010..To evaluate the complication of external magnet displacement in cochlear implant patients... - GJB2 gene mutations in cochlear implant recipients: prevalence and impact on outcomeLawrence R Lustig
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, JHOC, Baltimore, MD 21287, USA
Arch Otolaryngol Head Neck Surg 130:541-6. 2004..To determine the prevalence of GJB2 gene mutations in patients undergoing cochlear implantation (CI) and their impact on rehabilitative outcome following implantation... - Severe vestibular dysfunction and altered vestibular innervation in mice lacking prosaposinOmar Akil
Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, San Francisco, CA 94143 0449, United States
Neurosci Res 72:296-305. 2012.... - Expansile bone cyst and cholesteatoma of the temporal boneHarry S Hwang
Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, California, USA
Otol Neurotol 30:170-3. 2009..To identify primary bony cysts of the temporal bone... - Paget's disease and fibrous dysplasiaTimothy E Hullar
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, 601 North Caroline Street, Baltimore, MD, USA
Otolaryngol Clin North Am 36:707-32. 2003..As a better understanding of the etiology of these conditions develops and new pharmacotherapeutic agents are tested, it is likely that physicians will be able to turn to medical rather than surgical techniques to treat these disorders... - Hearing loss and the invention of the phonograph: the story of Thomas Alva EdisonCharles J Limb
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Otol Neurotol 23:96-101. 2002 - Comparison of the bone anchored hearing aid implantable hearing device with contralateral routing of offside signal amplification in the rehabilitation of unilateral deafnessJohn K Niparko
Department of Otolaryngology Head and Neck Surgery, Baltimore, MD 21287 0910, USA
Otol Neurotol 24:73-8. 2003.... - Restoration of brain stem auditory-evoked potential in maple syrup urine diseaseChristopher Spankovich
University of California San Francisco, San Francisco, California, USA
Otol Neurotol 28:566-9. 2007..The possible mechanism of the hearing loss and reversibility of wave I is proposed... - Current digital imaging for the otolaryngologistNikolas H Blevins
Department of Otolaryngology Head and Neck Surgery, Tufts University School of Medicine, Boston, Massachusetts, USA
Curr Opin Otolaryngol Head Neck Surg 11:166-72. 2003..This article is intended to introduce the fundamentals of digital imaging, and how this technology can best be integrated into an otolaryngology practice... - Pathology quiz case. Diagnosis: Glial choristoma of the middle earErik H Waldman
The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Arch Otolaryngol Head Neck Surg 131:363-4. 2005 - Characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) and alpha (alpha) 10 (CHRNA10) in lymphocytesHuashan Peng
The Center for Hearing Sciences, Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University, JHOC 6241, 601 N Caroline Street, Baltimore, MD 21287, USA
Life Sci 76:263-80. 2004..However, a lack of demonstrated response to applied acetylcholine using standard single-cell recording techniques suggests a physiology different than that seen in hair cells of the inner ear... - Fibrous dysplasia involving the skull base and temporal boneL R Lustig
Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University, JHOC Sixth Floor, 601 N Caroline St, Baltimore, MD 21287 0910, USA
Arch Otolaryngol Head Neck Surg 127:1239-47. 2001..To gain a broader appreciation of the clinical presentation, operative treatment, and outcome of patients with fibrous dysplasia involving the skull base... - Muscle-like nicotinic receptor accessory molecules in sensory hair cells of the inner earAbdullah A Osman
Department of Otolaryngology, Washington University School of Medicine, 660 South Euclid Ave, St Louis MO 63110, USA
Mol Cell Neurosci 38:153-69. 2008..Our data suggest that RIC-3 facilitates receptor function, while rapsyn enhances receptor clustering at the cell surface... - Otolaryngologic aspects of the Lewis & Clark Expedition, 1803-1806Marc D Eisen
Department of Otorhinolaryngology, University of Pennsylvania Medical Center, Philadelphia 19104, USA
Laryngoscope 112:1065-71. 2002..The custom of Clatsop Indian head flattening is also described. These descriptions also aim to illustrate the state of otolaryngology during the early 19th century in America...