Yi Luo

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. pmc Mycobacterium bovis bacillus Calmette-Guérin-induced macrophage cytotoxicity against bladder cancer cells
    Yi Luo
    Department of Urology, University of Iowa, 3202 MERF, Iowa City, IA 52242, USA
    Clin Dev Immunol 2010:357591. 2010
  2. pmc Intravesical dimethyl sulfoxide inhibits acute and chronic bladder inflammation in transgenic experimental autoimmune cystitis models
    Ronald Kim
    Department of Urology, Northwestern University, Chicago, IL 60611 3008, USA
    J Biomed Biotechnol 2011:937061. 2011
  3. pmc Bladder Cancer Immunotherapy: BCG and Beyond
    Eric J Askeland
    Department of Urology, University of Iowa, 375 Newton Road, 3204 MERF, Iowa City, IA 52242, USA
    Adv Urol 2012:181987. 2012
  4. pmc Urothelial antigen-specific CD4+ T cells function as direct effector cells and induce bladder autoimmune inflammation independent of CD8+ T cells
    W Liu
    Department of Urology, University of Iowa, Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA
    Mucosal Immunol 4:428-37. 2011
  5. pmc Interleukin-10 inhibits Mycobacterium bovis bacillus Calmette-Guérin (BCG)-induced macrophage cytotoxicity against bladder cancer cells
    Y Luo
    Department of Urology, University of Iowa, Iowa City, Iowa 52242, USA
    Clin Exp Immunol 160:359-68. 2010
  6. ncbi Use of prostate specific antigen to measure bladder tumor growth in a mouse orthotopic model
    Yi Luo
    University of Iowa Department of Urology, Iowa City, Iowa 52242, USA
    J Urol 172:2414-20. 2004
  7. pmc Role of Th1-stimulating cytokines in bacillus Calmette-Guérin (BCG)-induced macrophage cytotoxicity against mouse bladder cancer MBT-2 cells
    Y Luo
    Department of Urology, University of Iowa, Iowa City, IA 52242, USA
    Clin Exp Immunol 146:181-8. 2006
  8. pmc Th1 cytokine-secreting recombinant Mycobacterium bovis bacillus Calmette-Guérin and prospective use in immunotherapy of bladder cancer
    Yi Luo
    Department of Urology, University of Iowa, 375 Newton Road, 3202 MERF, Iowa City, IA 52242, USA
    Clin Dev Immunol 2011:728930. 2011
  9. pmc Mycobacterium bovis bacillus Calmette-Guérin (BCG) induces human CC- and CXC-chemokines in vitro and in vivo
    Y Luo
    Department of Urology, University of Iowa, Iowa City, IA 52242, USA
    Clin Exp Immunol 147:370-8. 2007
  10. ncbi Interferon-gamma up-regulates toll-like receptor 4 and cooperates with lipopolysaccharide to produce macrophage-derived chemokine and interferon-gamma inducible protein-10 in human bladder cancer cell line RT4
    Hiroshi Yamada
    Department of Urology, University of Iowa, Iowa City 52242, USA
    J Urol 174:1119-23. 2005

Collaborators

Detail Information

Publications50

  1. pmc Mycobacterium bovis bacillus Calmette-Guérin-induced macrophage cytotoxicity against bladder cancer cells
    Yi Luo
    Department of Urology, University of Iowa, 3202 MERF, Iowa City, IA 52242, USA
    Clin Dev Immunol 2010:357591. 2010
    ..This review summarizes the current understanding of the BCG-induced macrophage cytotoxicity toward bladder cancer cells with an intention to inspire investigation on this important but underdeveloped research field...
  2. pmc Intravesical dimethyl sulfoxide inhibits acute and chronic bladder inflammation in transgenic experimental autoimmune cystitis models
    Ronald Kim
    Department of Urology, Northwestern University, Chicago, IL 60611 3008, USA
    J Biomed Biotechnol 2011:937061. 2011
    ..Taken together, our results suggest that intravesical DMSO improves the bladder histopathology of IC/PBS patients because of its ability to interfere with multiple inflammatory and bladder cell types...
  3. pmc Bladder Cancer Immunotherapy: BCG and Beyond
    Eric J Askeland
    Department of Urology, University of Iowa, 375 Newton Road, 3204 MERF, Iowa City, IA 52242, USA
    Adv Urol 2012:181987. 2012
    ..This paper reviews the progress of basic science and clinical experience with several immunotherapeutic agents including IFN-α, IL-2, IL-12, and IL-10...
  4. pmc Urothelial antigen-specific CD4+ T cells function as direct effector cells and induce bladder autoimmune inflammation independent of CD8+ T cells
    W Liu
    Department of Urology, University of Iowa, Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA
    Mucosal Immunol 4:428-37. 2011
    ..These results indicate that urothelial Ag-specific CD4(+) T cells can function as direct effector cells to induce bladder autoimmune inflammation independent of CD8(+) T cells...
  5. pmc Interleukin-10 inhibits Mycobacterium bovis bacillus Calmette-Guérin (BCG)-induced macrophage cytotoxicity against bladder cancer cells
    Y Luo
    Department of Urology, University of Iowa, Iowa City, Iowa 52242, USA
    Clin Exp Immunol 160:359-68. 2010
    ..These results reveal the inhibitory role of IL-10 in BCG-induced macrophage cytotoxicity, suggesting that blockage of IL-10 may potentially enhance the effect of BCG in the treatment of bladder cancer patients...
  6. ncbi Use of prostate specific antigen to measure bladder tumor growth in a mouse orthotopic model
    Yi Luo
    University of Iowa Department of Urology, Iowa City, Iowa 52242, USA
    J Urol 172:2414-20. 2004
    ..However, to our knowledge there is currently no accurate method to quantify tumor growth inside the bladder in living animals. We used prostate specific antigen (PSA) as a marker to cope with this limitation...
  7. pmc Role of Th1-stimulating cytokines in bacillus Calmette-Guérin (BCG)-induced macrophage cytotoxicity against mouse bladder cancer MBT-2 cells
    Y Luo
    Department of Urology, University of Iowa, Iowa City, IA 52242, USA
    Clin Exp Immunol 146:181-8. 2006
    ....
  8. pmc Th1 cytokine-secreting recombinant Mycobacterium bovis bacillus Calmette-Guérin and prospective use in immunotherapy of bladder cancer
    Yi Luo
    Department of Urology, University of Iowa, 375 Newton Road, 3202 MERF, Iowa City, IA 52242, USA
    Clin Dev Immunol 2011:728930. 2011
    ..This paper discusses current rBCG research, concerns, and future directions with an intention to inspire the development of this very promising immunotherapeutic modality for bladder cancer...
  9. pmc Mycobacterium bovis bacillus Calmette-Guérin (BCG) induces human CC- and CXC-chemokines in vitro and in vivo
    Y Luo
    Department of Urology, University of Iowa, Iowa City, IA 52242, USA
    Clin Exp Immunol 147:370-8. 2007
    ..Taken together, these results indicate that BCG directly or indirectly induces human CC- and CXC-chemokine production, which may represent one of the mechanisms by which BCG exerts its anti-tumour activity...
  10. ncbi Interferon-gamma up-regulates toll-like receptor 4 and cooperates with lipopolysaccharide to produce macrophage-derived chemokine and interferon-gamma inducible protein-10 in human bladder cancer cell line RT4
    Hiroshi Yamada
    Department of Urology, University of Iowa, Iowa City 52242, USA
    J Urol 174:1119-23. 2005
    ..In this study we examined the signal mechanisms for inducting these 2 chemokines in RT4 cells by lipopolysaccharide (LPS), IFN-gamma and TNF-alpha...
  11. ncbi The essential role of interferon-gamma during interleukin-12 therapy for murine transitional cell carcinoma of the bladder
    Michael A O'Donnell
    Department of Urology, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
    J Urol 171:1336-42. 2004
    ..We investigated the mechanisms through which IL-12 induces antibladder cancer immunity...
  12. ncbi Recombinant bacillus Calmette-Guérin (BCG) expressing interferon-alpha 2B enhances human mononuclear cell cytotoxicity against bladder cancer cell lines in vitro
    Wujiang Liu
    Department of Urology, University of Iowa, 3202 MERF, 375 Newton Road, Iowa, IA 52242, USA
    Cancer Immunol Immunother 58:1647-55. 2009
    ..We demonstrated that rBCG-IFN-alpha augmented T helper type 1 (Th1) cytokine IFN-gamma production by PBMC. In this study, we further investigated whether rBCG-IFN-alpha could also enhance PBMC cytotoxicity toward bladder cancer cells...
  13. pmc RDP58 inhibits T cell-mediated bladder inflammation in an autoimmune cystitis model
    Wujiang Liu
    Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, 3202 MERF, 375 Newton Road, IA 52242 1087, USA
    J Autoimmun 30:257-65. 2008
    ....
  14. ncbi Role of Th1 and Th2 cytokines in BCG-induced IFN-gamma production: cytokine promotion and simulation of BCG effect
    Yi Luo
    Department of Urology, University of Iowa Hospitals and Clinics, 200 Hawkins Avenue, Iowa City, IA 52242, USA
    Cytokine 21:17-26. 2003
    ..These results suggest that combined Th1-stimulating cytokines and combinations of BCG plus selected Th1-stimulating cytokines are rational candidates for further study in the treatment of bladder cancer patients...
  15. ncbi Urinary bladder epithelium antigen induces CD8+ T cell tolerance, activation, and autoimmune response
    Wujiang Liu
    Department of Urology, University of Iowa Roy J and Lucille A Carven College of Medicine, Iowa City, IA 52242, USA
    J Immunol 178:539-46. 2007
    ..Taken together, we demonstrate for the first time that the bladder epithelium actively presents self-Ag to the immune system and induces CD8(+) T cell tolerance, activation, and autoimmune response...
  16. pmc Recombinant Mycobacterium bovis bacillus Calmette-Guérin (BCG) expressing mouse IL-18 augments Th1 immunity and macrophage cytotoxicity
    Y Luo
    Department of Urology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242 1089, USA
    Clin Exp Immunol 137:24-34. 2004
    ..Taken together, this rBCG-mIL-18 strain augments BCG's immunostimulatory property and may serve as a better agent for bladder cancer immunotherapy and antimycobacterial immunization...
  17. ncbi A novel expression of macrophage derived chemokine in human bladder cancer
    Hiroshi Yamada
    Department of Urology, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242 1089, USA
    J Urol 173:990-5. 2005
    ..Unfortunately, 30% to 40% of bladder tumors never respond to BCG. We sought evidence of antagonistic Th2 chemokine production by bladder tumors as a potential cause of BCG nonresponsiveness...
  18. ncbi Tumor necrosis factor-related apoptosis-inducing ligand: a novel mechanism for Bacillus Calmette-Guérin-induced antitumor activity
    Aaron T Ludwig
    Department of Urology, University of Iowa, Iowa City, Iowa 52242, USA
    Cancer Res 64:3386-90. 2004
    ..Flow cytometry of fresh urine revealed TRAIL-expressing neutrophils. Given these data, we propose TRAIL plays a role in BCG-induced antitumor effects...
  19. ncbi Interleukin-12 immunotherapy of murine transitional cell carcinoma of the bladder: dose dependent tumor eradication and generation of protective immunity
    Michael A O'Donnell
    Department of Urology, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
    J Urol 171:1330-5. 2004
    ..We evaluated the antibladder cancer activity of this cytokine in syngeneic mice bearing subcutaneous, metastatic and orthotopic tumors...
  20. doi Anti-interleukin-10R1 monoclonal antibody enhances bacillus Calmette-Guérin induced T-helper type 1 immune responses and antitumor immunity in a mouse orthotopic model of bladder cancer
    Nathan A Bockholt
    Department of Urology, University of Iowa, Iowa City, Iowa 52242, USA
    J Urol 187:2228-35. 2012
    ..We investigated whether blocking interleukin-10 receptor 1 would enhance the bacillus Calmette-Guérin induced T-helper type 1 immune response and anti-bladder cancer immunity in a mouse model...
  21. pmc Dose-dependent synergy of Th1-stimulating cytokines on bacille Calmette-Guérin-induced interferon-gamma production by human mononuclear cells
    X Chen
    Department of Urology, University of Iowa, Iowa City, IA, USA
    Clin Exp Immunol 149:178-85. 2007
    ..Taken together, these results suggest that combination of BCG with certain exogenous or endogenous (expressed by rBCGs) Th1-stimulating cytokines is a rational candidate for further study in bladder cancer treatment...
  22. pmc Interleukin 10 induced augmentation of delayed-type hypersensitivity (DTH) enhances Mycobacterium bovis bacillus Calmette-Guérin (BCG) mediated antitumour activity
    R Nadler
    Department of Urology, Northwestern University, Chicago, IL, USA
    Clin Exp Immunol 131:206-16. 2003
    ....
  23. pmc Nucleosomes accelerate transcription factor dissociation
    Yi Luo
    Biophysics Graduate Program, The Ohio State University, Columbus, OH 43210, USA, Department of Physics, The Ohio State University, Columbus, OH 43210, USA and Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA
    Nucleic Acids Res 42:3017-27. 2014
    ..Furthermore, these studies demonstrate that nucleosomes regulate DNA-protein interactions not only by preventing DNA-protein binding but by dramatically increasing the dissociation rate of protein complexes from their DNA-binding sites. ..
  24. ncbi Low nuclear levels of nuclear factor-kappa B are essential for KC self-induction in astrocytes: requirements for shuttling and phosphorylation
    Qiwei Zhai
    Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Glia 48:327-36. 2004
    ..The results outline a novel mechanism for NF-kappa B participation in transcription regulation...
  25. ncbi Manipulation of immune responses to Mycobacterium bovis by vaccination with IL-2- and IL-18-secreting recombinant bacillus Calmette Guerin
    Sarah Young
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Immunol Cell Biol 80:209-15. 2002
    ..The data suggest that manipulation of the immune response to tuberculosis and tuberculosis vaccines will require a more complete understanding of the factors that are important in generating a protective immune response...
  26. ncbi Regulation of lung injury and repair by Toll-like receptors and hyaluronan
    Dianhua Jiang
    Department of Medicine, Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut 06520, USA
    Nat Med 11:1173-9. 2005
    ..Hyaluronan-TLR2 and hyaluronan-TLR4 interactions provide signals that initiate inflammatory responses, maintain epithelial cell integrity and promote recovery from acute lung injury...
  27. ncbi RANTES stimulates inflammatory cascades and receptor modulation in murine astrocytes
    Yi Luo
    Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Glia 39:19-30. 2002
    ..Thus, after chemokine treatment, astrocytes release proinflammatory mediators and reprogram their surface molecules. The combined effects of RANTES may serve to amplify inflammatory responses within the central nervous system...
  28. doi Phospholipid transfer protein deficiency ameliorates diet-induced hypercholesterolemia and inflammation in mice
    Lorraine Shelly
    Department of Cardiovascular, Metabolic, and Endocrine Diseases, Pfizer Global Research Division, Pfizer, Inc, Groton, CT 06340, USA
    J Lipid Res 49:773-81. 2008
    ..Furthermore, plasma interleukin-6 levels are significantly lower in PLTP-deficient mice, indicating reduced systemic inflammation. These data suggest that PLTP appears to play a proatherogenic role in diet-induced hyperlipidemic mice...
  29. ncbi [Intraprostatic urinary reflux associated prostatitis caused by partial urethral obstruction in the rat model]
    Wei Liu
    Department of Urology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei 430071, China
    Zhonghua Nan Ke Xue 14:11-4. 2008
    ..To investigate the pathogenesis of chronic prostatitis / chronic pelvic pain syndrome (CP / CPPS) by constructing the rat model of intraprostatic urinary reflux associated prostatitis caused by partial urethral obstruction...
  30. doi A targeting drug-delivery model via interactions among cells and liposomes under ultrasonic excitation
    Xiaoyu Xi
    Institute of Acoustics, Lab of Modern Acoustics, Nanjing University, Nanjing 210093, People s Republic of China
    Phys Med Biol 53:3251-65. 2008
    ..25 MPa. It was found that the possible mechanisms might include the acoustic cavitation, the endocytosis and cell-fusion. Acoustic radiation force might make liposomes collide with cells effectively and facilitate the delivery process...
  31. ncbi Disulfide cross-linked hyaluronan hydrogels
    Xiao Zheng Shu
    Department of Medicinal Chemistry, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, Utah 84108 1257, USA
    Biomacromolecules 3:1304-11. 2002
    ..Thus, L-929 murine fibroblasts were encapsulated in HA-DTPH hydrogel; these cells remained viable and proliferated during 3 days of culture in vitro...
  32. doi 17beta-estradiol affects proliferation and apoptosis of rat prostatic smooth muscle cells by modulating cell cycle transition and related proteins
    Yi Luo
    Research Center of Urology and Andrology, Zhongnan Hospital, Wuhan University, 169 Donghu Road, Wuhan, Hubei 430071, PR China
    Cell Biol Int 32:899-905. 2008
    ..We thus suggest that an increase in estrogen may exert a launching effect in the pathology of BPH...
  33. doi Bletilla striata polysaccharide stimulates inducible nitric oxide synthase and proinflammatory cytokine expression in macrophages
    Huajia Diao
    State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, People s Republic of China
    J Biosci Bioeng 105:85-9. 2008
    ..In this study, we partially elucidate the wound healing mechanism of BSP...
  34. ncbi A role for Akt in epidermal growth factor-stimulated cell cycle progression in cultured hepatocytes: generation of a hyperproliferative window after adenoviral expression of constitutively active Akt
    Yi Luo
    The Cell Signaling Laboratory, The Hawthorn Building, Leicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK
    J Pharmacol Exp Ther 321:884-91. 2007
    ....
  35. ncbi RANTES-mediated chemokine transcription in astrocytes involves activation and translocation of p90 ribosomal S6 protein kinase (RSK)
    Ye Zhang
    Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 277:19042-8. 2002
    ..This novel role for RSK in signaling chemokine responses and synthesis in astrocytes may contribute to the amplification mechanisms responsible for prolonging inflammatory responses in the central nervous system...
  36. ncbi Targeted delivery of doxorubicin by HPMA copolymer-hyaluronan bioconjugates
    Yi Luo
    Department of Medicinal Chemistry, The University of Utah, Salt Lake City, USA
    Pharm Res 19:396-402. 2002
    ..An N-(2-hydroxypropyl)methacrylamide (HPMA)-HA polymeric drug delivery system was used for targeted delivery of doxorubicin to cancer cells...
  37. pmc Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway
    Yu Ting Yan
    Center for Advanced Biotechnology and Medicine and Department of Pediatric, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    Mol Cell Biol 22:4439-49. 2002
    ..Our findings highlight the significance of extracellular modulation of ligand activity as an important means of regulating TGF beta signaling pathways during vertebrate development...
  38. ncbi Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure
    Yu Sun
    Division of Molecular Medicine, Department of Medicine, Columbia University, New York, New York 10032, USA
    J Biol Chem 278:5813-20. 2003
    ..ABCA1-mediated cholesterol and phospholipid efflux may be uncoupled in pathological states associated with high SCD activity, as in hyperinsulinemic obese mice, or in animals treated with LXR activators...
  39. ncbi Negative role of cAMP-dependent protein kinase A in RANTES-mediated transcription of proinflammatory mediators through Raf
    Ye Zhang
    Department of Pathology, Harvard Medical School, Boston, MA 02115, USA
    FASEB J 17:734-6. 2003
    ..The results identify an upstream signaling pathway for amplification of proinflammatory mediators in the central nervous system...
  40. ncbi Development and preclinical evaluation of a Bacillus Calmette-Guérin-MUC1-based novel breast cancer vaccine
    Maureen A Chung
    Department of Surgery, Women and Infants Hospital, Brown University, Providence, Rhode Island 02905, USA
    Cancer Res 63:1280-7. 2003
    ..Our results suggest that BCG-hIL2MUC1 immunization inhibited breast cancer growth in hu-PBL-SCID mice. Therefore, BCG-hIL2MUC1 may be a promising candidate as a breast cancer vaccine...
  41. ncbi Tumor necrosis factor is required for RANTES-induced astrocyte monocyte chemoattractant protein-1 production
    Yi Luo
    Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Glia 43:119-27. 2003
    ..The results define an astrocyte proinflammatory cascade that amplifies synthesis of proinflammatory mediators. The implications of these findings to inflammatory diseases of the central nervous system are discussed...
  42. ncbi In situ crosslinkable hyaluronan hydrogels for tissue engineering
    Xiao Zheng Shu
    Department of Medicinal Chemistry, The University of Utah, 419 Wakara Way, Suite 205, Salt Lake City, UT 84108 1257, USA
    Biomaterials 25:1339-48. 2004
    ..These results confirm the potential utility of the HA-DTPH-PEGDA hydrogel as an in situ crosslinkable, injectable material for tissue engineering...
  43. ncbi Attachment of hyaluronan to metallic surfaces
    William G Pitt
    Chemical Engineering Department, Brigham Young University, 350 Clyde Building, Provo, UT 84602, USA
    J Biomed Mater Res A 68:95-106. 2004
    ..This type of controlled biological activity on a metal surface has potential for modulating cell growth and cellular interactions with metallic implants, such as vascular stents, orthopedic implants, heart valve cages, and more...
  44. pmc T-cell properties determine disease site, clinical presentation, and cellular pathology of experimental autoimmune encephalomyelitis
    Sara Abromson-Leeman
    Department of Pathology, Harvard Medical School, New Research Building, 77 Louis Pasteur Ave, Boston, MA 02115, USA
    Am J Pathol 165:1519-33. 2004
    ..These results highlight the multiplicity of T-cell-initiated effector pathways available for inflammation and demyelination...
  45. ncbi [Study on effect of danshensu in directional differentiation of mesenchymal stem cells into neuron-like cells]
    Qin Yu
    Zhejiang TCM College, Hangzhou 310053
    Zhongguo Zhong Xi Yi Jie He Za Zhi 25:49-53. 2005
    ..To study the effect of Danshensu (DSS) on directional differentiation of mesenchymal stem cells (MSC) into neuron-like cells...
  46. ncbi In vivo cleavage of alpha2,6-sialyltransferase by Alzheimer beta-secretase
    Shinobu Kitazume
    Glyco chain Functions Laboratory, The Institute of Physical and Chemical Research, RIKEN, 2 1 Hirosawa, Wako Shi, Saitama 351 0198, Japan
    J Biol Chem 280:8589-95. 2005
    ....
  47. pmc Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse
    Kyungmin Hahm
    Department of Exploratory Biology, Biogen Idec, 12 Cambridge Center, Cambridge, MA 02142, USA
    Am J Pathol 170:110-25. 2007
    ..These findings demonstrate that alpha v beta6 can contribute to the regulation of renal fibrosis and suggest this integrin as a potential therapeutic target...
  48. ncbi Adiponectin decreases plasma glucose and improves insulin sensitivity in diabetic Swine
    Xiaobo Hu
    Department of Biochemistry and Biotechnology, School of Life Sciences and Technology, Nanhua University, Hengyang 421001, China
    Acta Biochim Biophys Sin (Shanghai) 39:131-6. 2007
    ..05). Adiponectin might have the potential to be a glucose-lowering agent for metabolic disease. Adiponectin as a potent insulin enhancer linking adipose tissue and glucose metabolism could be useful to treat insulin resistance...
  49. ncbi Intracellular uptake and trafficking of Pluronic micelles in drug-sensitive and MDR cells: effect on the intracellular drug localization
    Natalya Rapoport
    Department of Bioengineering, University of Utah, 20 S 2030 E, Room 108, Salt Lake City, Utah, USA
    J Pharm Sci 91:157-70. 2002
    ..These findings suggest that the nuclear accumulation of drugs internalized via fluid-phase endocytosis can be enhanced by the application of Pluronic micelles and can be further augmented by ultrasonic irradiation...

Research Grants4

  1. BCG in Endogeneous and Exogenous Antigen-Induced T Cell
    Yi Luo; Fiscal Year: 2003
    ..abstract_text> ..
  2. BCG in Endogeneous and Exogenous Antigen-Induced T Cell
    Yi Luo; Fiscal Year: 2004
    ..abstract_text> ..
  3. Therapeutic Targeting Agents for Bladder Cancer
    Yi Luo; Fiscal Year: 2005
    ..abstract_text> ..
  4. BCG in Endogeneous and Exogenous Antigen-Induced T Cell
    Yi Luo; Fiscal Year: 2005
    ..abstract_text> ..