Research Topics
| R A LugoSummaryAffiliation: University of Utah Country: USA Publications
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Detail Information
Publications
Pharmacokinetics of methadoneRalph A Lugo
Department of Pharmacotherapy, University of Utah, Salt Lake City, UT, 84112 5820, USA
J Pain Palliat Care Pharmacother 19:13-24. 2005..General dosing guidelines, dosage conversions from other opioids and pharmacokinetic issues in special populations are discussed...
The pharmacokinetics of oxycodoneRalph A Lugo
Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City 84112 5820, USA
J Pain Palliat Care Pharmacother 18:17-30. 2004..Special populations, including children and those with liver/renal failure, have a unique oxycodone pharmacokinetic profile that must be taken into account in order to maximize analgesic efficacy and reduce the risk of adverse events...
Clinical pharmacokinetics of morphineRalph A Lugo
College of Pharmacy, and School of Medicine, University of Utah, Salt Lake City, UT 84112 5820, USA
J Pain Palliat Care Pharmacother 16:5-18. 2002....
Albuterol delivery in a neonatal ventilated lung model: Nebulization versus chlorofluorocarbon- and hydrofluoroalkane-pressurized metered dose inhalersR A Lugo
Department of Pharmacy Practice, University of Utah College of Pharmacy, 30 South 2000 East, Salt Lake City, UT 84112 5820, USA
Pediatr Pulmonol 31:247-54. 2001..There was no significant difference in drug delivery between CFC-MDI and HFA-MDI; nor did the placement of the spacer significantly affect drug delivery...
Enteral methadone to expedite fentanyl discontinuation and prevent opioid abstinence syndrome in the PICUR A Lugo
Department of Pharmacy Practice, College of Pharmacy, University of Utah, Salt Lake City 84112 5820, USA
Pharmacotherapy 21:1566-73. 2001..To determine if enterally administered methadone can facilitate fentanyl discontinuation and prevent withdrawal in children at high risk for opioid abstinence syndrome...
Albuterol delivery from a metered-dose inhaler with spacer is reduced following short-duration manual ventilation in a neonatal ventilator-lung modelRalph A Lugo
Department of Pharmacotherapy and Pediatrics, University of Utah College of Pharmacy and School of Medicine, Salt Lake City, 84112 5820
Respir Care 49:1029-34. 2004..However, minimizing the amount of time the spacer remains in line might also limit albuterol delivery to the patient...
Pharmacokinetics and pharmacodynamics of ranitidine in critically ill childrenR A Lugo
Department of Pharmacy Practice, the University of Utah College of Pharmacy, Salt Lake City, UT, USA
Crit Care Med 29:759-64. 2001..Thereafter, gastric pH should be monitored and the dose of ranitidine adjusted accordingly...
A cost analysis of enterally administered lorazepam in the pediatric intensive care unitR A Lugo
University of Utah College of Pharmacy and Department of Pharmacy, Primary Children s Medical Center, Salt Lake City 84112, USA
Crit Care Med 27:417-21. 1999..To determine the cost savings of replacing intravenous midazolam with enterally administered lorazepam in mechanically ventilated children who require long-term continuous sedation...
The effect of midazolam premedication on discharge time in pediatric patients undergoing general anesthesia for dental restorationsJ J Horgesheimer
Department of Pediatric Dentistry, University of Utah School of Medicine, Primary Children's Medical Center, Salt Lake City, USA
Pediatr Dent 23:491-4. 2001..CONCLUSIONS: Preoperative administration of oral midazolam does not delay discharge of children undergoing general anesthesia for dental rehabilitation...
The effect of confirmation calls on appointment-keeping behavior of patients in a children's hospital dental clinicA A Christensen
Department of Pediatric Dentistry, Primary Children's Medical Center, Salt Lake City, Utah, USA
Pediatr Dent 23:495-8. 2001..There was no difference between calls placed one or two working days prior to the appointment. The greatest reduction in broken appointments was shown in the private insurance group...
Analysis of fentanyl and norfentanyl in human plasma by liquid chromatography-tandem mass spectrometry using electrospray ionizationJ Day
Center for Human Toxicology, University of Utah, Salt Lake City, Utah 84112, USA
J Anal Toxicol 27:513-6. 2003..00-mm, 5 microLuna C18(2)) column. The intra-assay precision and accuracy ranged from 2.1 to 12.5% for both analytes at concentrations of 0.1, 0.5, 1.0, and 10 ng/mL. The interassay accuracy and precision ranged from 7.34 to 10.95%...
A survey of albuterol administration practices in intubated patients in the neonatal intensive care unitJulie Ballard
Respiratory Care Department, Primary Children s Medical Center, 100 North Medical Drive, Salt Lake City UT 84113 1100, USA
Respir Care 47:31-8. 2002....
Cardiovascular drugs for the newbornRobert M Ward
Division of Neonatology, University of Utah, 50 North Medical Drive, Salt Lake City, UT 84132, USA
Clin Perinatol 32:979-97, x. 2005..An effective pulmonary vasodilator must dilate the pulmonary vasculature more than the systemic vasculature...
The pharmacokinetics of the intravenous formulation of fentanyl citrate administered orally in children undergoing general anesthesiaMelissa Wheeler
Department of Pediatric Anesthesiology, 19, Children s Memorial Hospital, 2300 Children s Plaza, Chicago, IL 60614, USA
Anesth Analg 99:1347-51; table of contents. 2004..This suggests that this method of administration be used with caution until further data are available...
Misoprostol effects on diclofenac-induced cardiorenal changes in salt-sensitive patients with hypertension: the MEDIC StudyMark A Munger
Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, Utah 84112 5820, USA
Pharmacotherapy 28:834-42. 2008..To determine whether coadministration of misoprostol with the nonsteroidal antiinflammatory drug diclofenac lessens the increase in blood pressure and improves the alterations in renal hemodynamics induced by diclofenac...
Postoperative opiate analgesia requirements of smokers and nonsmokersFreddy M Creekmore
College of Pharmacy, University of Utah, 30 S 2000 East, Room 258, Salt Lake City, UT 84112 5820, USA
Ann Pharmacother 38:949-53. 2004..Abrupt discontinuation of nicotine in nicotine-dependent patients appears to increase the perception of pain. The clinical importance of nicotine's effect on pain perception is not fully understood...
Effect of perioperative administration of ropivacaine with epinephrine on postoperative pediatric adenotonsillectomy recoveryAlbert H Park
Department of Surgery, University of Utah, Salt Lake City, USA
Arch Otolaryngol Head Neck Surg 130:459-64. 2004..To determine whether perioperative administration of ropivacaine hydrochloride with epinephrine decreases postoperative pain following adenotonsillectomy and to determine the pharmacokinetics of ropivacaine following injection...
Chronically inhaled salmeterol improves pulmonary function in heart failureTien M H Ng
Department of Pharmacy Practice, University of Utah Health Sciences Center, Salt Lake City, UT, USA
J Cardiovasc Pharmacol 40:140-5. 2002..The plasma half-life of salmeterol may be prolonged in heart failure patients, thus leading to accumulation at steady-state...
Failure of nasogastric omeprazole suspension in pediatric intensive care patientsJulie A Haizlip
Department of Pediatrics, University of Virginia Children's Medical Center, Charlottesville, USA
Pediatr Crit Care Med 6:182-7. 2005..Half of the studied subjects either required significant dose titrations to achieve gastric acid suppression or did not respond to nasogastric administration of omeprazole suspension...
The use of haloperidol in agitated critically ill childrenA Marc Harrison
Department of Pediatric Critical Care Medicine, Cleveland Clinic Children's Hospital, Ohio, USA
Clin Pediatr (Phila) 41:51-4. 2002
