Research Topics
| David R LucasSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
Identification of SYT-SSX transcripts from synovial sarcomas using RT-multiplex PCR and capillary electrophoresisJohn A Thorson
Department of Pathology, University of Michigan, Ann Arbor, MI 48105, USA
Mod Pathol 19:641-7. 2006..One-step RT-multiplex PCR combined with capillary electrophoresis is a rapid and accurate method for the detection and genotypic classification of SYT-SSX transcripts from fixed tissue specimens...
Tenosynovial giant cell tumor: case report and reviewDavid R Lucas
Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA
Arch Pathol Lab Med 136:901-6. 2012..Herein, I report a case of intra-articular, localized tenosynovial giant cell tumor (or localized pigmented villonodular synovitis) and review the classification, histopathology, and recent developments regarding its pathogenesis...- Dedifferentiated liposarcoma with inflammatory myofibroblastic tumor-like featuresDavid R Lucas
Department of Pathology, University of Michigan, Ann Arbor, MI 48109 0054, USA
Am J Surg Pathol 34:844-51. 2010..Awareness of this finding can prevent one from misdiagnosing dedifferentiated liposarcoma as inflammatory myofibroblastic tumor, a much less aggressive neoplasm... - OsteoblastomaDavid R Lucas
Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA
Arch Pathol Lab Med 134:1460-6. 2010.... - Histologic alterations from neoadjuvant chemotherapy in high-grade extremity soft tissue sarcoma: clinicopathological correlationDavid R Lucas
Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109 0054, USA
Oncologist 13:451-8. 2008.... - Metastatic shoulder liposarcoma to the right ventricle: CT findingsAamer Chughtai
Department of Radiology, Division of Cardiothoracic Radiology, University of Michigan Medical Center, Ann Arbor, Michigan, USA
J Thorac Imaging 22:195-8. 2007.... - Results of a phase II study of sirolimus and cyclophosphamide in patients with advanced sarcomaScott M Schuetze
Division of Hematology Oncology, Department of Medicine, University of Michigan, Ann Arbor, MI 48109 5848, United States
Eur J Cancer 48:1347-53. 2012..The combination of sirolimus and cyclophosphamide demonstrated synergistic anti-sarcoma activity in preclinical models; therefore, we conducted a phase II trial of sirolimus and cyclophosphamide in patients with advanced sarcoma... - Phase II trial of cetuximab in patients with metastatic or locally advanced soft tissue or bone sarcomaHuan T Ha
Moses Cone Reg Cancer Ctr, Greensboro, NC, USA
Am J Clin Oncol 36:77-82. 2013..In vitro studies suggest a role of the EGFR pathway in growth and differentiation in some sarcomas. We conducted a phase II trial of cetuximab, a monoclonal antibody to EGFR, in patients with advanced sarcomas... - Adjuvant therapy of osteosarcoma--A Phase II trial: Southwest Oncology Group study 9139Mark M Zalupski
Department of Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA
Cancer 100:818-25. 2004.... - Chordoma: the nonsarcoma primary bone tumorRashmi Chugh
Department of Internal Medicine, Division of Hematology Oncology, 24 Frank Lloyd Wright Drive, A3400, P O Box 483, Ann Arbor, Michigan 48106, USA
Oncologist 12:1344-50. 2007..Radiation therapy may also salvage some patients with local recurrence. One series reported a 2-year actuarial local control rate of 33% for patients treated with proton beam irradiation... - Primary versus radiation-associated craniofacial osteosarcoma: Biologic and clinicopathologic comparisonsJonathan B McHugh
Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109-0054, USA
Cancer 107:554-62. 2006..In addition, they demonstrate higher expression rates of adverse prognostic indicators, further highlighting the distinction... - Extra-abdominal desmoid tumor with osseous involvementYaseen Oweis
Division of Musculoskeletal Radiology, Department of Radiology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
Skeletal Radiol 41:483-7. 2012..We report a case of an extra-abdominal desmoid tumor involving the teres minor muscle in a symptomatic 42-year-old woman with unusual features of medullary involvement and negative nuclear beta-catenin staining... - Can lymphangiosarcoma be resurrected? A clinicopathological and immunohistochemical study of lymphatic differentiation in 49 angiosarcomasCohra C Mankey
Department of Pathology, University of Michigan, Ann Arbor, MI 48109 0054, USA
Histopathology 56:364-71. 2010..The aim was to investigate further lymphatic antigen expression, and to explore the relation of immunohistochemistry to morphological and clinical findings... - Fine-needle aspiration of spinal osteoblastoma in a patient with lymphangiomatosisMichael G Rhode
Department of Pathology, University of Michigan Medical School, Ann Arbor, USA
Diagn Cytopathol 34:295-7. 2006..We believe that this is the first case reporting an osteoblastoma diagnosed by FNA in a lymphangiomatosis patient. We describe the clinical and cytological findings of osteoblastoma and its differential diagnosis... - Long-term outcomes after radiotherapy for retroperitoneal and deep truncal sarcomaMary Feng
Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI, USA
Int J Radiat Oncol Biol Phys 69:103-10. 2007..To determine the long-term outcomes after multimodality treatment of retroperitoneal, pelvic, and deep truncal sarcomas and to identify the factors associated with local control (LC), distant metastasis (DM), and overall survival (OS)... - Cluster analysis of immunohistochemical profiles in synovial sarcoma, malignant peripheral nerve sheath tumor, and Ewing sarcomaStephen H Olsen
Department of Pathology, The University of Michigan Medical School, Ann Arbor, MI 48109-0054, USA
Mod Pathol 19:659-68. 2006..Cluster analysis also highlighted aberrant staining reactions and diagnostic pitfalls in these tumors. Hierarchical cluster analysis is an effective method for analyzing high-volume immunohistochemical data... - Sino-orbital osteoma: a clinicopathologic study of 45 surgically treated cases with emphasis on tumors with osteoblastoma-like featuresJonathan B McHugh
Department of Pathology, University of Michigan Health System, Ann Arbor, MI 48109 0054, USA
Arch Pathol Lab Med 133:1587-93. 2009..Osteomas may have osteoblastoma-like areas and distinguishing it from true osteoblastoma can be challenging. Some believe osteomas with osteoblastoma-like features behave more aggressively... - Cluster analysis of immunohistochemical markers in leiomyosarcoma delineates specific anatomic and gender subgroupsJason C Carvalho
Department of Pathology, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0054, USA
Cancer 115:4186-95. 2009..The differential expression of smooth muscle markers, estrogen receptor (ER), progesterone receptor (PR), and Wilms tumor-1 protein (WT1) by anatomic subtype and gender was explored... - Cardiac pseudosarcomatous fibromyxoid tumor: a review of the literatureAamer Chughtai
Division of Thoracic Radiology, Department of Radiology, University of Michigan Medical Center, Ann Arbor, MI 48109, USA
J Comput Assist Tomogr 29:749-51. 2005..No recurrence or metastatic disease has been reported after resection of PFTs elsewhere in the body, and this tumor seems to have a benign clinical course... - Wagner-Meissner neurilemmoma of the right cheekAngela J Wu
Department of Pathology, University of Michigan, MI 48109 0054, USA
Ann Diagn Pathol 12:204-7. 2008.... - Cutaneous and subcutaneous pleomorphic liposarcoma: a clinicopathologic study of 29 cases with evaluation of MDM2 gene amplification in 26Jerad M Gardner
Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA
Am J Surg Pathol 36:1047-51. 2012..The low incidence of MDM2 gene amplification in our series indicates that most superficial PLs are unrelated to WDL/DL. PL likely evolves by way of more than 1 molecular pathway... - Angiosarcoma, radiation-associated angiosarcoma, and atypical vascular lesionDavid R Lucas
Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA
Arch Pathol Lab Med 133:1804-9. 2009..Recently, vascular-type atypical vascular lesion, which resembles hemangioma, has been described, thus expanding the definition of this entity... - Sonography of fat necrosis involving the extremity and torso with magnetic resonance imaging and histologic correlationMichael Walsh
Department of Radiology, University of Michigan Medical Center, Ann Arbor, MI 48109 0326, USA
J Ultrasound Med 27:1751-7. 2008..The purpose of this study was to describe the sonographic appearance of pathologically proven isolated fat necrosis involving the extremities or torso with magnetic resonance imaging (MRI) correlation... 
Gemcitabine-mediated radiosensitization of human soft tissue sarcomaJames D Murphy
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA
Transl Oncol 1:50-6. 2008..The purpose of this study was to determine the radiosensitizing potential of gemcitabine in preclinical models of human STS...- Disseminated malignant solitary fibrous tumor of the pleuraHongquan Zhang
Department of Pathology, Harper University Hospital, Wayne State University and Karmanos Cancer Institute, Detroit, MI 48201, USA
Pathol Int 54:111-5. 2004.... - Phase II study of neoadjuvant chemotherapy and radiation therapy in the management of high-risk, high-grade, soft tissue sarcomas of the extremities and body wall: Radiation Therapy Oncology Group Trial 9514William G Kraybill
Department of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
J Clin Oncol 24:619-25. 2006..On the basis of a positive reported single-institution pilot study, the Radiation Therapy Oncology Group initiated phase II trial 9514 to evaluate its neoadjuvant regimen in a multi-institutional Intergroup setting... - Epidermal growth factor receptor expression and mutational analysis in synovial sarcomas and malignant peripheral nerve sheath tumorsHussein Tawbi
Department of, Division of Hematology Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA
Oncologist 13:459-66. 2008..The present study extends that work to examine the expression of EGFR in MPNSTs and the characterization of potential targets of the EGFR tyrosine kinase domain...