Gitta H Lubke

Summary

Affiliation: University of Notre Dame
Country: USA

Publications

  1. pmc Multivariate genetic analyses in heterogeneous populations
    Gitta Lubke
    University of Notre Dame, 118 Haggar Hall, Notre Dame, IN, 46556, USA
    Behav Genet 44:232-9. 2014
  2. pmc Estimating the genetic variance of major depressive disorder due to all single nucleotide polymorphisms
    Gitta H Lubke
    Department of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA
    Biol Psychiatry 72:707-9. 2012
  3. pmc The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses
    Gitta H Lubke
    Department of Psychology, University of Notre Dame, 118 Haggar Hall, Notre Dame, IN 46556, USA
    Behav Genet 42:636-46. 2012
  4. ncbi request reprint Investigating population heterogeneity with factor mixture models
    Gitta H Lubke
    Department of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA
    Psychol Methods 10:21-39. 2005
  5. pmc Maternal ratings of attention problems in ADHD: evidence for the existence of a continuum
    Gitta H Lubke
    Department of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA
    J Am Acad Child Adolesc Psychiatry 48:1085-93. 2009
  6. doi request reprint Genetic Analyses Benefit From Using Less Heterogeneous Phenotypes: An Illustration With the Hospital Anxiety and Depression Scale (HADS)
    Charles A Laurin
    Department of Psychology, University of Notre Dame, Notre Dame, Indiana, United States of America Integrated Epidemiology Unit, School of Social and Community Medicine, University of Bristol, United Kingdom
    Genet Epidemiol 39:317-24. 2015
  7. pmc An integrated approach to reduce the impact of minor allele frequency and linkage disequilibrium on variable importance measures for genome-wide data
    Raymond Walters
    Department of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA
    Bioinformatics 28:2615-23. 2012
  8. doi request reprint Epi2Loc: an R package to investigate two-locus epistatic models
    Raymond K Walters
    Department of Psychology, University of Notre Dame, Notre Dame, IN, USA
    Twin Res Hum Genet 17:272-8. 2014
  9. ncbi request reprint Subtypes versus severity differences in attention-deficit/hyperactivity disorder in the Northern Finnish Birth Cohort
    Gitta H Lubke
    University of Notre Dame, Notre Dame, IN, USA
    J Am Acad Child Adolesc Psychiatry 46:1584-93. 2007

Detail Information

Publications10

  1. pmc Multivariate genetic analyses in heterogeneous populations
    Gitta Lubke
    University of Notre Dame, 118 Haggar Hall, Notre Dame, IN, 46556, USA
    Behav Genet 44:232-9. 2014
    ..A first evaluation with simulated data shows a substantial increase of power compared to univariate GWAS. ..
  2. pmc Estimating the genetic variance of major depressive disorder due to all single nucleotide polymorphisms
    Gitta H Lubke
    Department of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA
    Biol Psychiatry 72:707-9. 2012
    ..The pattern of results is consistent with estimates of heritability obtained in twin studies carried out in the same population...
  3. pmc The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses
    Gitta H Lubke
    Department of Psychology, University of Notre Dame, 118 Haggar Hall, Notre Dame, IN 46556, USA
    Behav Genet 42:636-46. 2012
    ..Taken together, our study provides evidence for a general role of the CHRNA5/A3/B4 gene cluster in substance use initiation that is not limited to nicotine and alcohol...
  4. ncbi request reprint Investigating population heterogeneity with factor mixture models
    Gitta H Lubke
    Department of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA
    Psychol Methods 10:21-39. 2005
    ..A step-by-step analysis of a subset of data from the Longitudinal Survey of American Youth illustrates how factor mixture models can be applied in an exploratory fashion to data collected at a single time point...
  5. pmc Maternal ratings of attention problems in ADHD: evidence for the existence of a continuum
    Gitta H Lubke
    Department of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA
    J Am Acad Child Adolesc Psychiatry 48:1085-93. 2009
    ....
  6. doi request reprint Genetic Analyses Benefit From Using Less Heterogeneous Phenotypes: An Illustration With the Hospital Anxiety and Depression Scale (HADS)
    Charles A Laurin
    Department of Psychology, University of Notre Dame, Notre Dame, Indiana, United States of America Integrated Epidemiology Unit, School of Social and Community Medicine, University of Bristol, United Kingdom
    Genet Epidemiol 39:317-24. 2015
    ..Homogeneity can be increased by focusing on core symptoms of disorders, thus reducing the noise in aggregate phenotypes caused by substantially different symptom profiles. ..
  7. pmc An integrated approach to reduce the impact of minor allele frequency and linkage disequilibrium on variable importance measures for genome-wide data
    Raymond Walters
    Department of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA
    Bioinformatics 28:2615-23. 2012
    ..To establish RF and GBM as viable alternatives for analyzing genome-wide data, it is necessary to address this potential bias and show that SL methods do not significantly under-perform conventional GWAS methods...
  8. doi request reprint Epi2Loc: an R package to investigate two-locus epistatic models
    Raymond K Walters
    Department of Psychology, University of Notre Dame, Notre Dame, IN, USA
    Twin Res Hum Genet 17:272-8. 2014
    ..The usefulness of the package for model interpretation and power analysis is illustrated using data on rheumatoid arthritis. ..
  9. ncbi request reprint Subtypes versus severity differences in attention-deficit/hyperactivity disorder in the Northern Finnish Birth Cohort
    Gitta H Lubke
    University of Notre Dame, Notre Dame, IN, USA
    J Am Acad Child Adolesc Psychiatry 46:1584-93. 2007
    ....