Research Topics
| F L LuanSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
Universal prophylaxis is cost effective in cytomegalovirus serology-positive kidney transplant patientsFu L Luan
Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Transplantation 91:237-44. 2011..We performed cost effectiveness and cost utility modeling comparing these two approaches...
New-onset diabetes mellitus in kidney transplant recipients discharged on steroid-free immunosuppressionFu L Luan
Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109 0364, USA
Transplantation 91:334-41. 2011..New-onset diabetes after transplant (NODAT) is a serious complication after kidney transplantation. We studied the relationship between steroid-free maintenance regimens and NODAT in a national cohort of adult kidney transplant patients...
The time interval between kidney and pancreas transplantation and the clinical outcomes of pancreas after kidney transplantationFu L Luan
Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI 48109 0364, USA
Clin Transplant 26:403-10. 2012..Shortening the time interval between pancreas and kidney transplantation to less than three yr may reduce the risk of kidney graft loss in qualified PAK transplant candidates...
Six-month prophylaxis is cost effective in transplant patients at high risk for cytomegalovirus infectionFu L Luan
Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan, USA
J Am Soc Nephrol 20:2449-58. 2009..In summary, 6-mo prophylaxis with valganciclovir combined with a one-time determination of viremia is cost effective in reducing CMV infection and disease in seronegative recipients of seropositive kidney and/or pancreas transplants...
Metabolic syndrome and new onset diabetes after transplantation in kidney transplant recipientsFu L Luan
Internal Medicine, Division of Nephrology, University of Michigan Taubman Center, East Medical Center Drive, Ann Arbor, MI, USA
Clin Transplant 24:778-83. 2010..Metabolic syndrome (MS) and new onset diabetes after transplant (NODAT) are common in kidney transplant patients. We studied the relationship between the two conditions and their impact on metabolic and cardiovascular risk profiles...
Abnormal glucose metabolism and metabolic syndrome in non-diabetic kidney transplant recipients early after transplantationFu L Luan
Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Transplantation 89:1034-9. 2010..We prospectively studied the relationship between AGM and MS in non-diabetic kidney transplant recipients early after transplantation...
Transplantation in diabetic kidney failure patients: modalities, outcomes, and clinical managementFu L Luan
Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA
Semin Dial 23:198-205. 2010..Finally, re-transplantation should be recommended in suitable kidney transplant patients when the kidney allograft demonstrates continuous and progressive decline in function...
Choice of induction regimens on the risk of cytomegalovirus infection in donor-positive and recipient-negative kidney transplant recipientsF L Luan
Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan, USA
Transpl Infect Dis 12:473-9. 2010..We investigated the impact of various antibody induction regimens on CMV infection in this group of patients...
Influence of recipient race on the outcome of simultaneous pancreas and kidney transplantationF L Luan
Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Am J Transplant 10:2074-81. 2010..42, 95% CI 1.15, 1.75, p = 0.001). In the era of modern immunosuppression, AA SPK transplant patients continue to have inferior graft outcome. Additional studies to explore the mechanisms of such racial disparity are warranted...
Impact of cytomegalovirus disease in D+/R- kidney transplant patients receiving 6 months low-dose valganciclovir prophylaxisF L Luan
Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA
Am J Transplant 11:1936-42. 2011..15-7.61, p = 0.025). In conclusion, late-onset CMV disease continues to negatively impact kidney transplant outcome despite 6-month low-dose VGCV prophylaxis. Investigations focusing on novel preventive approaches should be emphasized...
Steroid-free maintenance immunosuppression in kidney transplantation: is it time to consider it as a standard therapy?Fu L Luan
Department of Internal Medicine, University of Michigan, Ann Arbor, 48109 0364, USA
Kidney Int 76:825-30. 2009....
A pilot study of gene expression-based categorization of pancreas transplant biopsiesFu L Luan
Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA corrected
Transplantation 87:222-6. 2009..Three of those four pancreas transplants were subsequently lost. Our study demonstrates the potential association of gene expression with clinical outcome of pancreas transplants and justifies further studies in an independent cohort...
Efficacy of valganciclovir in the treatment of cytomegalovirus disease in kidney and pancreas transplant recipientsF L Luan
Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA
Transplant Proc 38:3673-5. 2006..Valganciclovir allowed for early initiation of treatment and for treatment to be given as an outpatient. These advantages of valganciclovir have both health and economic impact for patients with CMV disease...
Impact of simultaneous pancreas and kidney transplantation on cardiovascular risk factors in patients with type 1 diabetes mellitusFu L Luan
Internal Medicine, Division of Nephrology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
Transplantation 84:541-4. 2007..We conclude that SPK significantly improves blood pressure and dyslipidemia compared with KTA in type 1 diabetic ESRD patients...
Impact of immunosuppressive regimen on survival of kidney transplant recipients with hepatitis CFu L Luan
Division of Nephrology, Department of Medicine, University of Michigan Health System, Ann Arbor, MI, USA
Transplantation 85:1601-6. 2008..HCV-positive kidney transplant recipients have worse clinical outcomes than those who are HCV negative. The optimal immunosuppressive regimen in this group of patients remains uncertain...
Comparative risk of impaired glucose metabolism associated with cyclosporine versus tacrolimus in the late posttransplant periodF L Luan
Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA
Am J Transplant 8:1871-7. 2008..4% in group I and group II, respectively (p = 0.90). In conclusion, conversion to Tac, compared to continuous exposure to CsA, carries quantitatively similar risk of impaired glucose metabolism in KTRs in the late posttransplant period...
Graft and patient survival in kidney transplant recipients selected for de novo steroid-free maintenance immunosuppressionF L Luan
Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA
Am J Transplant 9:160-8. 2009..De novo steroid-free immunosuppression as currently practiced in the United States appears to carry no increased risk of adverse clinical outcomes in the intermediate term...
Management of hypertension in solid-organ transplantationJeong M Park
University of Michigan, Ann Arbor, MI, USA
Prog Transplant 15:17-22. 2005..The choice of an antihypertensive regimen should be tailored on the basis of the individual patient's risk factors and comorbidities...
Rapamycin is an effective inhibitor of human renal cancer metastasisFu L Luan
Department of Medicine, Weill Medical College of Cornell University, New York-Presbyterian Hospital New York, New York, USA
Kidney Int 63:917-26. 2003....
Kidney transplantation from donors without a heartbeatFu L Luan
N Engl J Med 347:1799-801; author reply 1799-801. 2002
Intensive glucose control in type 2 diabetesFu L Luan
N Engl J Med 359:1519-20; author reply 1520-1. 2008
Rapamycin blocks tumor progression: unlinking immunosuppression from antitumor efficacyFu L Luan
Department of Transplantation Medicine, New York-Presbyterian Hospital, New York, NY 10021, USA
Transplantation 73:1565-72. 2002..CONCLUSIONS: Our findings, in addition to unlinking mechanisms of immunosuppression from that of tumor progression, suggest that rapamycin may be of value for the management of posttransplant malignancy...
