- Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branchingYubing Lu
Gladstone Institute of Neurological Disease, and Department of Neurology, University of California, San Francisco, CA 94158, USA
Mol Brain 2:30. 2009..In diseased neurons, TDP-43 is depleted in the nucleus, suggesting a loss-of-function pathogenic mechanism. However, the normal function of TDP-43 in postmitotic neurons is largely unknown...
- The Drosophila homologue of the Angelman syndrome ubiquitin ligase regulates the formation of terminal dendritic branchesYubing Lu
Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA
Hum Mol Genet 18:454-62. 2009..These findings suggest that dendritic pathology may contribute to neurological deficits in patients with Angelman syndrome...