Research Topics
| B LozoffSummaryAffiliation: University of Michigan Country: USA Publications
Research Grants
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Detail Information
Publications
Preschool-aged children with iron deficiency anemia show altered affect and behaviorBetsy Lozoff
Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109 0406, USA
J Nutr 137:683-9. 2007..These results indicate that IDA in the preschool period has affective and behavioral effects similar to those reported for IDA in infancy...- Iron-fortified vs low-iron infant formula: developmental outcome at 10 yearsBetsy Lozoff
Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109 5406, USA
Arch Pediatr Adolesc Med 166:208-15. 2012..To assess long-term developmental outcome in children who received iron-fortified or low-iron formula... 
Behavior of infants with iron-deficiency anemiaB Lozoff
Center for Human Growth and Development, University of Michigan, Ann Arbor 48109 0406, USA
Child Dev 69:24-36. 1998....- Long-lasting neural and behavioral effects of iron deficiency in infancyBetsy Lozoff
Center for Human Growth and Development and the Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor 48109, USA
Nutr Rev 64:S34-43; discussion S72-91. 2006..Research in animal models points to mechanisms for such long-lasting effects. Potential mechanisms relate to effects of iron deficiency during brain development on neurometabolism, myelination, and neurotransmitter function... - Iron status of inner-city African-American infantsBetsy Lozoff
Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109, USA
Am J Hematol 82:112-21. 2007..Functional indicators of poor iron status in young infants are urgently needed... - Double burden of iron deficiency in infancy and low socioeconomic status: a longitudinal analysis of cognitive test scores to age 19 yearsBetsy Lozoff
Center for Human Growth and Development, and Department of Pediatrics and Communicable Diseases, University of Michigan, 300 N Ingalls, Ann Arbor, MI 48109, USA
Arch Pediatr Adolesc Med 160:1108-13. 2006..To assess change in cognitive functioning after iron deficiency in infancy, depending on socioeconomic status (SES; middle vs low)... - Iron deficiency and brain developmentBetsy Lozoff
Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109 0406, USA
Semin Pediatr Neurol 13:158-65. 2006..This body of research emphasizes the importance of protecting the developing brain from ID... - Iron deficiency in infancy: applying a physiologic framework for predictionBetsy Lozoff
Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109 0406, USA
Am J Clin Nutr 84:1412-21. 2006..Infants aged 6-24 mo are at high risk of iron deficiency. Numerous studies worldwide have sought to identify predictors of iron deficiency in this age group... - Dose-response relationships between iron deficiency with or without anemia and infant social-emotional behaviorBetsy Lozoff
Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109 5406, USA
J Pediatr 152:696-702, 702.31-3. 2008..To assess dose-response relationships between severity of iron deficiency (ID) and infant social-emotional behavior... - Eye-blinking rates are slower in infants with iron-deficiency anemia than in nonanemic iron-deficient or iron-sufficient infantsBetsy Lozoff
Center for Human Growth and Development and 4Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109, USA
J Nutr 140:1057-61. 2010..The clinical importance of a lower eye-blink rate is unclear, but impaired dopamine functioning is likely to have broader impact, given the role dopamine plays in regulating movement, motivation, cognition, and hormone release... - Home intervention improves cognitive and social-emotional scores in iron-deficient anemic infantsBetsy Lozoff
Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, 300 N Ingalls, University of Michigan, Ann Arbor, MI 48109 5406, USA
Pediatrics 126:e884-94. 2010..Iron-deficiency anemia (IDA) is associated with alterations in infant behavior and development that may not be corrected with iron therapy... - Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancyB Lozoff
Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109 0406, USA
Pediatrics 105:E51. 2000..To determine the long-term effects of iron deficiency in infancy... - Iron deficiency and child developmentBetsy Lozoff
Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, 300 N Ingalls, Ann Arbor, MI 48109 5406, USA
Food Nutr Bull 28:S560-71. 2007..New findings also point to the need for more attention to the developmental effects of prenatal iron deficiency... - Behavioral and developmental effects of preventing iron-deficiency anemia in healthy full-term infantsBetsy Lozoff
Center for Human Growth and Development and Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan 48109 0406, USA
Pediatrics 112:846-54. 2003..To determine the behavioral and developmental effects of preventing iron-deficiency anemia in infancy... - Early iron deficiency has brain and behavior effects consistent with dopaminergic dysfunctionBetsy Lozoff
Center for Human Growth and Development and Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109, USA
J Nutr 141:740S-746S. 2011.... - Twenty-four-hour motor activity in human infants with and without iron deficiency anemiaR M Angulo-Kinzler
Center for Human Motor Research, Division of Kinesiology, University of Michigan, Ann Arbor, MI 48109 2214, USA
Early Hum Dev 70:85-101. 2002..Infants with IDA were less active in the laboratory than in the home. The home versus laboratory results suggest that contextual factors affect the motor activity of IDA infants to a larger extent than controls... - Iron deficiency and infant motor developmentTal Shafir
Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109 5406, USA
Early Hum Dev 84:479-85. 2008..Iron deficiency (ID) during early development impairs myelination and basal ganglia function in animal models... - Iron deficiency in infancy and mother-child interaction at 5 yearsFeyza Corapci
Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109-0406, USA
J Dev Behav Pediatr 27:371-8. 2006..Sustained differences in mother-child interaction might contribute to the long-lasting behavioral and developmental alterations reported in children with chronic, severe iron deficiency in infancy... - Spontaneous motor activity in human infants with iron-deficiency anemiaR M Angulo-Kinzler
Division of Kinesiology, Center for Human Motor Research, University of Michigan, 401 Washtenaw Avenue, Ann Arbor, MI 48109 2214, USA
Early Hum Dev 66:67-79. 2002.... - Iron deficiency anemia in infancy and reach and grasp developmentTal Shafir
The Molecular and Behavioral Neuroscience Institute MBNI, University of Michigan, 205 Zina Pitcher Pl, Rm 1066, Ann Arbor, MI 48109 0720, USA
Infant Behav Dev 32:366-75. 2009..Poorer upper-extremity control in IDA infants in the short-term in this study and in the long-term despite iron therapy in other studies suggests that a motor intervention may be warranted when IDA is detected in infancy... - Iron deficiency in infancy predicts altered serum prolactin response 10 years laterBarbara Felt
Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109 0406, USA
Pediatr Res 60:513-7. 2006..In conclusion, an altered serum prolactin response pattern was observed 10 y after chronic ID in infancy and may suggest a long-lasting effect of ID on the regulation of prolactin... - Breast-feeding and mental and motor development at 51/2 yearsKaty M Clark
Center for Human Growth and Development, University of Michigan, Ann Arbor, 48109, USA
Ambul Pediatr 6:65-71. 2006..The latter finding requires replication in other samples where long breast-feeding is common and socioeconomic status is relatively homogeneous... - Motor development in 9-month-old infants in relation to cultural differences and iron statusRosa M Angulo-Barroso
Center for Human Growth and Development, School of Kinesiology, University of Michigan, 300 N Ingalls, 10th Floor, Ann Arbor, MI 48109 5406, USA
Dev Psychobiol 53:196-210. 2011..Our findings add to the sparse literature on infant fine motor development across cultures. The results also indicate the need to consider nutritional factors when examining cultural differences in infant development... - Persistent neurochemical and behavioral abnormalities in adulthood despite early iron supplementation for perinatal iron deficiency anemia in ratsBarbara T Felt
Center for Human Growth and Development and Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, 48109, USA
Behav Brain Res 171:261-70. 2006..We recently reported that rats with chronic perinatal IDA, had altered regional brain iron, monoamines, and sensorimotor skill emergence during early development... - Effects of iron deficiency in infancy on patterns of motor development over timeTal Shafir
Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109-0406, United States
Hum Mov Sci 25:821-38. 2006..Thus, there was no evidence of catch-up in motor development, despite iron therapy in infancy that corrected iron deficiency anemia in all cases... 
Occupational exposure to pesticides during pregnancy and neurobehavioral development of infants and toddlersAlexis J Handal
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
Epidemiology 19:851-9. 2008..This study considers the potential effects of maternal occupation in the cut-flower industry during pregnancy on neurobehavioral development in Ecuadorian children...- Sociodemographic and nutritional correlates of neurobehavioral development: a study of young children in a rural region of EcuadorAlexis J Handal
University of Michigan School of Public Health, Department of Epidemiology, Ann Arbor, Michigan, USA
Rev Panam Salud Publica 21:292-300. 2007..To identify and describe the sociodemographic and nutritional characteristics associated with neurobehavioral development among young children living in three communities in the northeastern Andean region of Cayambe-Tabacundo, Ecuador... - Longitudinal evaluation of externalizing and internalizing behavior problems following iron deficiency in infancyFeyza Corapci
Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, 300 N Ingalls, Ann Arbor, MI 48109 0406, USA
J Pediatr Psychol 35:296-305. 2010..This study examined externalizing and internalizing behavior problem trajectories as a function of both iron status in infancy and infant characteristics... - Effect of community of residence on neurobehavioral development in infants and young children in a flower-growing region of EcuadorAlexis J Handal
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan 48105, USA
Environ Health Perspect 115:128-33. 2007.... - Neurobehavioral development in children with potential exposure to pesticidesAlexis J Handal
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
Epidemiology 18:312-20. 2007..This preliminary study conducted in Ecuador examines the association between household and environmental risk factors for pesticide exposure and neurobehavioral development... - Higher infant blood lead levels with longer duration of breastfeedingBetsy Lozoff
Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA
J Pediatr 155:663-7. 2009..To determine whether longer breastfeeding is associated with higher infant lead concentrations... - The role of verbal competence and multiple risk on the internalizing behavior problems of Costa Rican youthFeyza Corapci
Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan, USA
Ann N Y Acad Sci 1094:278-81. 2006..The results raise the possibility that interventions to improve verbal competence might help lower the risk of internalizing problems in the face of early adversity... - Behavioral consequences of developmental iron deficiency in infant rhesus monkeysMari S Golub
Department of Environmental Toxicology, CNRPC, Room 1925, University of California, Davis, One Shields Avenue, Davis, CA 95616, United States
Neurotoxicol Teratol 28:3-17. 2006.... - Maternal depression in three Latin American samplesAbraham W Wolf
Department of Psychiatry, MetroHealth Medical Center, Cleveland, OH 44109, USA
Soc Psychiatry Psychiatr Epidemiol 37:169-76. 2002.... - Do breast-fed babies benefit from iron before 6 months?Betsy Lozoff
J Pediatr 143:554-6. 2003 - Effects of iron therapy on infant blood lead levelsAbraham W Wolf
Department of Psychiatry, MetroHealth Medical Center, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44109, USA
J Pediatr 143:789-95. 2003..To determine the effects of iron therapy on blood lead levels in infants with mildly elevated lead levels and varied iron status... - Rapid drop in infant blood lead levels during the transition to unleaded gasoline use in Santiago, ChilePaulina Pino
School of Public Health, Faculty of Medicine, University of Chile, Santiago, Chile
Arch Environ Health 59:182-7. 2004..In this study, the authors demonstrated that infant blood lead levels, even if relatively low, can drop very rapidly in conjunction with decreases in environmental lead exposure... - Diet-induced iron deficiency anemia and pregnancy outcome in rhesus monkeysMari S Golub
University of California, Davis, Davis, CA 95616, USA
Am J Clin Nutr 83:647-56. 2006..Iron deficiency anemia (IDA) is relatively common in the third trimester of pregnancy, but causal associations with low birth weight and compromised neonatal iron status are difficult to establish in human populations... - Child development: risk factors for adverse outcomes in developing countriesSusan P Walker
Epidemiology Research Unit, The University of the West Indies, Mona, Jamaica
Lancet 369:145-57. 2007..Furthermore, risks often occur together or cumulatively, with concomitant increased adverse effects on the development of the world's poorest children... - Iron deficiency anemia in infancy is associated with altered temporal organization of sleep states in childhoodPatricio D Peirano
Sleep Laboratory, Institute of Nutrition and Food Technology INTA, University of Chile, Macul, Santiago 7830489, Chile
Pediatr Res 62:715-9. 2007..The results show that early IDA is associated with long-lasting alterations in the temporal organization of sleep patterns... - Anemia and iron deficiency in pregnant Ghanaian women from urban areasCyril Engmann
Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7596, USA
Int J Gynaecol Obstet 101:62-6. 2008..To determine the prevalence and identify risk factors for iron deficiency and anemia in pregnant Ghanaian women from urban areas... - Iron-deficiency anemia is associated with altered characteristics of sleep spindles in NREM sleep in infancyPatricio Peirano
Sleep and Functional Neurobiology Laboratory, Institute of Nutrition and Food Technology INTA, University of Chile, AV JP Alessandri 5540, Santiago, 11, Chile
Neurochem Res 32:1665-72. 2007..To determine the effects of iron-deficiency anemia on the development of non-rapid-eye-movement (NREM) sleep stages, as indexed by sleep spindles... - Iron deficiency anemia in infancy: long-lasting effects on auditory and visual system functioningCecilia Algarín
Laboratory of Sleep and Functional Neurobiology, INTA, University of Chile, Chile
Pediatr Res 53:217-23. 2003..Subtle changes in sensory pathway transmission might be an underlying mechanism for the derailment of other developmental aspects in early IDA... - An event-related potential study of attention and recognition memory in infants with iron-deficiency anemiaMatthew J Burden
Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, 2751 E Jefferson, Suite 460, Detroit, MI 48207, USA
Pediatrics 120:e336-45. 2007..The purpose of this work was to determine whether iron-deficiency anemia in infancy represents a risk factor for deficits in attention and memory development using event-related potentials... - Policies to reduce undernutrition include child developmentMaureen M Black
University of Maryland School of Medicine, Baltimore, MD 21201, USA
Lancet 371:454-5. 2008
Research Grants
- Neuromaturational Delays in Iron Deficient Anemic InfantsBetsy Lozoff; Fiscal Year: 2007..Long-term ill effects continuing into adolescence, despite iron therapy in infancy, could therefore have major public health implications. ..
- Timing, Duration and Severity of Infant Iron Deficiency: Developmental ImpactsBetsy Lozoff; Fiscal Year: 2009....
- Neuromaturational Delays in Iron Deficient Anemic InfantsBetsy Lozoff; Fiscal Year: 2009..Long-term ill effects continuing into adolescence, despite iron therapy in infancy, could therefore have major public health implications. ..
- Timing, Duration and Severity of Infant Iron Deficiency: Developmental ImpactsBetsy Lozoff; Fiscal Year: 2010....
- Neuromaturational Delays in Iron Deficient Anemic InfantsBetsy Lozoff; Fiscal Year: 2010..Long-term ill effects continuing into adolescence, despite iron therapy in infancy, could therefore have major public health implications. ..
- Timing, Duration and Severity of Infant Iron Deficiency: Developmental ImpactsBetsy Lozoff; Fiscal Year: 2009....
- Brain and Behavior in Early Iron DeficiencyBetsy Lozoff; Fiscal Year: 2007..Collectively, the program will make a major contribution in understanding, treating, and preventing brain and behavior effects of iron deficiency, the world's most common single nutrient disorder. ..
- FUNCTIONAL SIGNIFICANCE OF EARLY IRON DEFICIENCYBetsy Lozoff; Fiscal Year: 2007..abstract_text> ..
- Timing, Duration and Severity of Infant Iron Deficiency: Developmental ImpactsBetsy Lozoff; Fiscal Year: 2007....
- NEUROMATURATION DELAYS IN IRON DEFICIENT ANEMIC INFANTSBetsy Lozoff; Fiscal Year: 2000..s. ..
- Neuromaturational Delays in Iron Deficient Anemic InfantBetsy Lozoff; Fiscal Year: 2005....
- Timing, Duration and Severity of Infant Iron Deficiency: Developmental ImpactsBetsy Lozoff; Fiscal Year: 2010....