B Lozoff

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc Preschool-aged children with iron deficiency anemia show altered affect and behavior
    Betsy Lozoff
    Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109 0406, USA
    J Nutr 137:683-9. 2007
  2. pmc Iron-fortified vs low-iron infant formula: developmental outcome at 10 years
    Betsy Lozoff
    Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109 5406, USA
    Arch Pediatr Adolesc Med 166:208-15. 2012
  3. ncbi request reprint Behavior of infants with iron-deficiency anemia
    B Lozoff
    Center for Human Growth and Development, University of Michigan, Ann Arbor 48109 0406, USA
    Child Dev 69:24-36. 1998
  4. pmc Long-lasting neural and behavioral effects of iron deficiency in infancy
    Betsy Lozoff
    Center for Human Growth and Development and the Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor 48109, USA
    Nutr Rev 64:S34-43; discussion S72-91. 2006
  5. pmc Iron status of inner-city African-American infants
    Betsy Lozoff
    Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109, USA
    Am J Hematol 82:112-21. 2007
  6. pmc Double burden of iron deficiency in infancy and low socioeconomic status: a longitudinal analysis of cognitive test scores to age 19 years
    Betsy Lozoff
    Center for Human Growth and Development, and Department of Pediatrics and Communicable Diseases, University of Michigan, 300 N Ingalls, Ann Arbor, MI 48109, USA
    Arch Pediatr Adolesc Med 160:1108-13. 2006
  7. ncbi request reprint Iron deficiency and brain development
    Betsy Lozoff
    Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109 0406, USA
    Semin Pediatr Neurol 13:158-65. 2006
  8. pmc Iron deficiency in infancy: applying a physiologic framework for prediction
    Betsy Lozoff
    Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109 0406, USA
    Am J Clin Nutr 84:1412-21. 2006
  9. pmc Dose-response relationships between iron deficiency with or without anemia and infant social-emotional behavior
    Betsy Lozoff
    Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109 5406, USA
    J Pediatr 152:696-702, 702.31-3. 2008
  10. pmc Eye-blinking rates are slower in infants with iron-deficiency anemia than in nonanemic iron-deficient or iron-sufficient infants
    Betsy Lozoff
    Center for Human Growth and Development and 4Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109, USA
    J Nutr 140:1057-61. 2010

Collaborators

Detail Information

Publications45

  1. pmc Preschool-aged children with iron deficiency anemia show altered affect and behavior
    Betsy Lozoff
    Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109 0406, USA
    J Nutr 137:683-9. 2007
    ..These results indicate that IDA in the preschool period has affective and behavioral effects similar to those reported for IDA in infancy...
  2. pmc Iron-fortified vs low-iron infant formula: developmental outcome at 10 years
    Betsy Lozoff
    Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109 5406, USA
    Arch Pediatr Adolesc Med 166:208-15. 2012
    ..To assess long-term developmental outcome in children who received iron-fortified or low-iron formula...
  3. ncbi request reprint Behavior of infants with iron-deficiency anemia
    B Lozoff
    Center for Human Growth and Development, University of Michigan, Ann Arbor 48109 0406, USA
    Child Dev 69:24-36. 1998
    ....
  4. pmc Long-lasting neural and behavioral effects of iron deficiency in infancy
    Betsy Lozoff
    Center for Human Growth and Development and the Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor 48109, USA
    Nutr Rev 64:S34-43; discussion S72-91. 2006
    ..Research in animal models points to mechanisms for such long-lasting effects. Potential mechanisms relate to effects of iron deficiency during brain development on neurometabolism, myelination, and neurotransmitter function...
  5. pmc Iron status of inner-city African-American infants
    Betsy Lozoff
    Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109, USA
    Am J Hematol 82:112-21. 2007
    ..Functional indicators of poor iron status in young infants are urgently needed...
  6. pmc Double burden of iron deficiency in infancy and low socioeconomic status: a longitudinal analysis of cognitive test scores to age 19 years
    Betsy Lozoff
    Center for Human Growth and Development, and Department of Pediatrics and Communicable Diseases, University of Michigan, 300 N Ingalls, Ann Arbor, MI 48109, USA
    Arch Pediatr Adolesc Med 160:1108-13. 2006
    ..To assess change in cognitive functioning after iron deficiency in infancy, depending on socioeconomic status (SES; middle vs low)...
  7. ncbi request reprint Iron deficiency and brain development
    Betsy Lozoff
    Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109 0406, USA
    Semin Pediatr Neurol 13:158-65. 2006
    ..This body of research emphasizes the importance of protecting the developing brain from ID...
  8. pmc Iron deficiency in infancy: applying a physiologic framework for prediction
    Betsy Lozoff
    Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109 0406, USA
    Am J Clin Nutr 84:1412-21. 2006
    ..Infants aged 6-24 mo are at high risk of iron deficiency. Numerous studies worldwide have sought to identify predictors of iron deficiency in this age group...
  9. pmc Dose-response relationships between iron deficiency with or without anemia and infant social-emotional behavior
    Betsy Lozoff
    Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109 5406, USA
    J Pediatr 152:696-702, 702.31-3. 2008
    ..To assess dose-response relationships between severity of iron deficiency (ID) and infant social-emotional behavior...
  10. pmc Eye-blinking rates are slower in infants with iron-deficiency anemia than in nonanemic iron-deficient or iron-sufficient infants
    Betsy Lozoff
    Center for Human Growth and Development and 4Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109, USA
    J Nutr 140:1057-61. 2010
    ..The clinical importance of a lower eye-blink rate is unclear, but impaired dopamine functioning is likely to have broader impact, given the role dopamine plays in regulating movement, motivation, cognition, and hormone release...
  11. pmc Home intervention improves cognitive and social-emotional scores in iron-deficient anemic infants
    Betsy Lozoff
    Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, 300 N Ingalls, University of Michigan, Ann Arbor, MI 48109 5406, USA
    Pediatrics 126:e884-94. 2010
    ..Iron-deficiency anemia (IDA) is associated with alterations in infant behavior and development that may not be corrected with iron therapy...
  12. ncbi request reprint Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancy
    B Lozoff
    Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109 0406, USA
    Pediatrics 105:E51. 2000
    ..To determine the long-term effects of iron deficiency in infancy...
  13. ncbi request reprint Iron deficiency and child development
    Betsy Lozoff
    Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, 300 N Ingalls, Ann Arbor, MI 48109 5406, USA
    Food Nutr Bull 28:S560-71. 2007
    ..New findings also point to the need for more attention to the developmental effects of prenatal iron deficiency...
  14. ncbi request reprint Behavioral and developmental effects of preventing iron-deficiency anemia in healthy full-term infants
    Betsy Lozoff
    Center for Human Growth and Development and Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan 48109 0406, USA
    Pediatrics 112:846-54. 2003
    ..To determine the behavioral and developmental effects of preventing iron-deficiency anemia in infancy...
  15. pmc Early iron deficiency has brain and behavior effects consistent with dopaminergic dysfunction
    Betsy Lozoff
    Center for Human Growth and Development and Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109, USA
    J Nutr 141:740S-746S. 2011
    ....
  16. ncbi request reprint Twenty-four-hour motor activity in human infants with and without iron deficiency anemia
    R M Angulo-Kinzler
    Center for Human Motor Research, Division of Kinesiology, University of Michigan, Ann Arbor, MI 48109 2214, USA
    Early Hum Dev 70:85-101. 2002
    ..Infants with IDA were less active in the laboratory than in the home. The home versus laboratory results suggest that contextual factors affect the motor activity of IDA infants to a larger extent than controls...
  17. pmc Iron deficiency and infant motor development
    Tal Shafir
    Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109 5406, USA
    Early Hum Dev 84:479-85. 2008
    ..Iron deficiency (ID) during early development impairs myelination and basal ganglia function in animal models...
  18. pmc Iron deficiency in infancy and mother-child interaction at 5 years
    Feyza Corapci
    Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48109 0406, USA
    J Dev Behav Pediatr 27:371-8. 2006
    ..Sustained differences in mother-child interaction might contribute to the long-lasting behavioral and developmental alterations reported in children with chronic, severe iron deficiency in infancy...
  19. ncbi request reprint Spontaneous motor activity in human infants with iron-deficiency anemia
    R M Angulo-Kinzler
    Division of Kinesiology, Center for Human Motor Research, University of Michigan, 401 Washtenaw Avenue, Ann Arbor, MI 48109 2214, USA
    Early Hum Dev 66:67-79. 2002
    ....
  20. pmc Iron deficiency anemia in infancy and reach and grasp development
    Tal Shafir
    The Molecular and Behavioral Neuroscience Institute MBNI, University of Michigan, 205 Zina Pitcher Pl, Rm 1066, Ann Arbor, MI 48109 0720, USA
    Infant Behav Dev 32:366-75. 2009
    ..Poorer upper-extremity control in IDA infants in the short-term in this study and in the long-term despite iron therapy in other studies suggests that a motor intervention may be warranted when IDA is detected in infancy...
  21. pmc Iron deficiency in infancy predicts altered serum prolactin response 10 years later
    Barbara Felt
    Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109 0406, USA
    Pediatr Res 60:513-7. 2006
    ..In conclusion, an altered serum prolactin response pattern was observed 10 y after chronic ID in infancy and may suggest a long-lasting effect of ID on the regulation of prolactin...
  22. pmc Breast-feeding and mental and motor development at 51/2 years
    Katy M Clark
    Center for Human Growth and Development, University of Michigan, Ann Arbor, 48109, USA
    Ambul Pediatr 6:65-71. 2006
    ..This study assesses the issue in a low socioeconomic status sample where breast-feeding was close to universal...
  23. pmc Motor development in 9-month-old infants in relation to cultural differences and iron status
    Rosa M Angulo-Barroso
    Center for Human Growth and Development, School of Kinesiology, University of Michigan, 300 N Ingalls, 10th Floor, Ann Arbor, MI 48109 5406, USA
    Dev Psychobiol 53:196-210. 2011
    ..Our findings add to the sparse literature on infant fine motor development across cultures. The results also indicate the need to consider nutritional factors when examining cultural differences in infant development...
  24. pmc Persistent neurochemical and behavioral abnormalities in adulthood despite early iron supplementation for perinatal iron deficiency anemia in rats
    Barbara T Felt
    Center for Human Growth and Development and Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, 48109, USA
    Behav Brain Res 171:261-70. 2006
    ..We recently reported that rats with chronic perinatal IDA, had altered regional brain iron, monoamines, and sensorimotor skill emergence during early development...
  25. pmc Effects of iron deficiency in infancy on patterns of motor development over time
    Tal Shafir
    Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109 0406, United States
    Hum Mov Sci 25:821-38. 2006
    ..Thus, there was no evidence of catch-up in motor development, despite iron therapy in infancy that corrected iron deficiency anemia in all cases...
  26. doi request reprint Occupational exposure to pesticides during pregnancy and neurobehavioral development of infants and toddlers
    Alexis J Handal
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
    Epidemiology 19:851-9. 2008
    ..This study considers the potential effects of maternal occupation in the cut-flower industry during pregnancy on neurobehavioral development in Ecuadorian children...
  27. ncbi request reprint Sociodemographic and nutritional correlates of neurobehavioral development: a study of young children in a rural region of Ecuador
    Alexis J Handal
    University of Michigan School of Public Health, Department of Epidemiology, Ann Arbor, Michigan, USA
    Rev Panam Salud Publica 21:292-300. 2007
    ..To identify and describe the sociodemographic and nutritional characteristics associated with neurobehavioral development among young children living in three communities in the northeastern Andean region of Cayambe-Tabacundo, Ecuador...
  28. pmc Longitudinal evaluation of externalizing and internalizing behavior problems following iron deficiency in infancy
    Feyza Corapci
    Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, 300 N Ingalls, Ann Arbor, MI 48109 0406, USA
    J Pediatr Psychol 35:296-305. 2010
    ..This study examined externalizing and internalizing behavior problem trajectories as a function of both iron status in infancy and infant characteristics...
  29. pmc Effect of community of residence on neurobehavioral development in infants and young children in a flower-growing region of Ecuador
    Alexis J Handal
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan 48105, USA
    Environ Health Perspect 115:128-33. 2007
    ....
  30. ncbi request reprint Neurobehavioral development in children with potential exposure to pesticides
    Alexis J Handal
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
    Epidemiology 18:312-20. 2007
    ..This preliminary study conducted in Ecuador examines the association between household and environmental risk factors for pesticide exposure and neurobehavioral development...
  31. pmc Higher infant blood lead levels with longer duration of breastfeeding
    Betsy Lozoff
    Center for Human Growth and Development, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA
    J Pediatr 155:663-7. 2009
    ..To determine whether longer breastfeeding is associated with higher infant lead concentrations...
  32. pmc The role of verbal competence and multiple risk on the internalizing behavior problems of Costa Rican youth
    Feyza Corapci
    Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan, USA
    Ann N Y Acad Sci 1094:278-81. 2006
    ..The results raise the possibility that interventions to improve verbal competence might help lower the risk of internalizing problems in the face of early adversity...
  33. pmc Behavioral consequences of developmental iron deficiency in infant rhesus monkeys
    Mari S Golub
    Department of Environmental Toxicology, CNRPC, Room 1925, University of California, Davis, One Shields Avenue, Davis, CA 95616, United States
    Neurotoxicol Teratol 28:3-17. 2006
    ....
  34. ncbi request reprint Maternal depression in three Latin American samples
    Abraham W Wolf
    Department of Psychiatry, MetroHealth Medical Center, Cleveland, OH 44109, USA
    Soc Psychiatry Psychiatr Epidemiol 37:169-76. 2002
    ....
  35. ncbi request reprint Do breast-fed babies benefit from iron before 6 months?
    Betsy Lozoff
    J Pediatr 143:554-6. 2003
  36. ncbi request reprint Effects of iron therapy on infant blood lead levels
    Abraham W Wolf
    Department of Psychiatry, MetroHealth Medical Center, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44109, USA
    J Pediatr 143:789-95. 2003
    ..To determine the effects of iron therapy on blood lead levels in infants with mildly elevated lead levels and varied iron status...
  37. ncbi request reprint Rapid drop in infant blood lead levels during the transition to unleaded gasoline use in Santiago, Chile
    Paulina Pino
    School of Public Health, Faculty of Medicine, University of Chile, Santiago, Chile
    Arch Environ Health 59:182-7. 2004
    ..In this study, the authors demonstrated that infant blood lead levels, even if relatively low, can drop very rapidly in conjunction with decreases in environmental lead exposure...
  38. pmc Diet-induced iron deficiency anemia and pregnancy outcome in rhesus monkeys
    Mari S Golub
    University of California, Davis, Davis, CA 95616, USA
    Am J Clin Nutr 83:647-56. 2006
    ..Iron deficiency anemia (IDA) is relatively common in the third trimester of pregnancy, but causal associations with low birth weight and compromised neonatal iron status are difficult to establish in human populations...
  39. ncbi request reprint Child development: risk factors for adverse outcomes in developing countries
    Susan P Walker
    Epidemiology Research Unit, The University of the West Indies, Mona, Jamaica
    Lancet 369:145-57. 2007
    ..Furthermore, risks often occur together or cumulatively, with concomitant increased adverse effects on the development of the world's poorest children...
  40. pmc Iron deficiency anemia in infancy is associated with altered temporal organization of sleep states in childhood
    Patricio D Peirano
    Sleep Laboratory, Institute of Nutrition and Food Technology INTA, University of Chile, Macul, Santiago 7830489, Chile
    Pediatr Res 62:715-9. 2007
    ..The results show that early IDA is associated with long-lasting alterations in the temporal organization of sleep patterns...
  41. ncbi request reprint Anemia and iron deficiency in pregnant Ghanaian women from urban areas
    Cyril Engmann
    Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7596, USA
    Int J Gynaecol Obstet 101:62-6. 2008
    ..To determine the prevalence and identify risk factors for iron deficiency and anemia in pregnant Ghanaian women from urban areas...
  42. pmc Iron-deficiency anemia is associated with altered characteristics of sleep spindles in NREM sleep in infancy
    Patricio Peirano
    Sleep and Functional Neurobiology Laboratory, Institute of Nutrition and Food Technology INTA, University of Chile, AV JP Alessandri 5540, Santiago, 11, Chile
    Neurochem Res 32:1665-72. 2007
    ..To determine the effects of iron-deficiency anemia on the development of non-rapid-eye-movement (NREM) sleep stages, as indexed by sleep spindles...
  43. ncbi request reprint Iron deficiency anemia in infancy: long-lasting effects on auditory and visual system functioning
    Cecilia Algarín
    Laboratory of Sleep and Functional Neurobiology, INTA, University of Chile, Chile
    Pediatr Res 53:217-23. 2003
    ..Subtle changes in sensory pathway transmission might be an underlying mechanism for the derailment of other developmental aspects in early IDA...
  44. pmc An event-related potential study of attention and recognition memory in infants with iron-deficiency anemia
    Matthew J Burden
    Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, 2751 E Jefferson, Suite 460, Detroit, MI 48207, USA
    Pediatrics 120:e336-45. 2007
    ..The purpose of this work was to determine whether iron-deficiency anemia in infancy represents a risk factor for deficits in attention and memory development using event-related potentials...
  45. doi request reprint Policies to reduce undernutrition include child development
    Maureen M Black
    University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Lancet 371:454-5. 2008

Research Grants25

  1. Neuromaturational Delays in Iron Deficient Anemic Infants
    Betsy Lozoff; Fiscal Year: 2007
    ..Long-term ill effects continuing into adolescence, despite iron therapy in infancy, could therefore have major public health implications. ..
  2. Timing, Duration and Severity of Infant Iron Deficiency: Developmental Impacts
    Betsy Lozoff; Fiscal Year: 2009
    ....
  3. Neuromaturational Delays in Iron Deficient Anemic Infants
    Betsy Lozoff; Fiscal Year: 2009
    ..Long-term ill effects continuing into adolescence, despite iron therapy in infancy, could therefore have major public health implications. ..
  4. Timing, Duration and Severity of Infant Iron Deficiency: Developmental Impacts
    Betsy Lozoff; Fiscal Year: 2010
    ....
  5. Neuromaturational Delays in Iron Deficient Anemic Infants
    Betsy Lozoff; Fiscal Year: 2010
    ..Long-term ill effects continuing into adolescence, despite iron therapy in infancy, could therefore have major public health implications. ..
  6. Timing, Duration and Severity of Infant Iron Deficiency: Developmental Impacts
    Betsy Lozoff; Fiscal Year: 2009
    ....
  7. Brain and Behavior in Early Iron Deficiency
    Betsy Lozoff; Fiscal Year: 2007
    ..Collectively, the program will make a major contribution in understanding, treating, and preventing brain and behavior effects of iron deficiency, the world's most common single nutrient disorder. ..
  8. FUNCTIONAL SIGNIFICANCE OF EARLY IRON DEFICIENCY
    Betsy Lozoff; Fiscal Year: 2007
    ..abstract_text> ..
  9. Timing, Duration and Severity of Infant Iron Deficiency: Developmental Impacts
    Betsy Lozoff; Fiscal Year: 2007
    ....
  10. NEUROMATURATION DELAYS IN IRON DEFICIENT ANEMIC INFANTS
    Betsy Lozoff; Fiscal Year: 2000
    ..s. ..
  11. Neuromaturational Delays in Iron Deficient Anemic Infant
    Betsy Lozoff; Fiscal Year: 2005
    ....
  12. Timing, Duration and Severity of Infant Iron Deficiency: Developmental Impacts
    Betsy Lozoff; Fiscal Year: 2010
    ....