Affiliation: University of Texas Southwestern Medical Center
Country: USA
Publications
Lovett Racke A, Rocchini A, Choy J, Northrop S, Hussain R, Ratts R, et al. Silencing T-bet defines a critical role in the differentiation of autoreactive T lymphocytes. Immunity. 2004;21:719-31 pubmed
..Since T-bet regulates IFNgamma production in CD4(+) T cells, but to a lesser extent in most other IFNgamma-producing cells, T-bet may be a target for therapeutics for Th1-mediated diseases. ..