Research Topics
| Andrew T LoveringSummaryAffiliation: University of Oregon Country: USA Publications
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Detail Information
Publications
Responses and limitations of the respiratory system to exerciseAndrew T Lovering
The John Rankin Laboratory of Pulmonary Medicine, Department of Population Health Sciences, University of Wisconsin at Madison, Madison, WI 53706 1532, USA
Clin Chest Med 26:439-57, vi. 2005..Nonetheless, there are several exceptional cases in which the lung is unable to accommodate the demands of exercise because of vascular or airway limitations...
Tonic and phasic drive to medullary respiratory neurons during periodic breathingAndrew T Lovering
Texas Tech University School of Medicine, Department of Physiology, Lubbock, TX 79430 6551, USA
Respir Physiol Neurobiol 181:286-301. 2012....
Intrapulmonary shunting and pulmonary gas exchange during normoxic and hypoxic exercise in healthy humansAndrew T Lovering
Department of Human Physiology, 1240 University of Oregon, Eugene, OR 97403 1240, USA
J Appl Physiol 104:1418-25. 2008..Whether oxygen tension specifically regulates these novel pathways or opens them indirectly via effects on the conventional pulmonary vasculature remains unclear...
Hyperoxia prevents exercise-induced intrapulmonary arteriovenous shunt in healthy humansAndrew T Lovering
Department of Human Physiology, 1240 University of Oregon, Eugene, OR 97403 1240, USA
J Physiol 586:4559-65. 2008..Our results suggest that alveolar hyperoxia prevents or reduces blood flow through arteriovenous shunt pathways...
Transpulmonary passage of 99mTc macroaggregated albumin in healthy humans at rest and during maximal exerciseAndrew T Lovering
Department of Human Physiology, University of Oregon, Eugene, OR 97403 1240, USA
J Appl Physiol 106:1986-92. 2009..Recruitment of these pathways may divert blood flow away from pulmonary capillaries during exercise and compromise the lung's function as a biological filter...
Pulmonary pathways and mechanisms regulating transpulmonary shunting into the general circulation: an updateAndrew T Lovering
Department of Human Physiology, University of Oregon, Cardiopulmonary and Respiratory Physiology Laboratory, Eugene, OR 97401, USA
Injury 41:S16-23. 2010..Finally, we suggest some precautionary measures that should be taken during interventions to keep intrapulmonary arteriovenous anastomoses closed in order to prevent or reduce the incidence of paradoxical embolism...
Medullary respiratory neural activity during hypoxia in NREM and REM sleep in the catAndrew T Lovering
Texas Tech University School of Medicine, Department of Physiology, Lubbock, Texas, USA
J Neurophysiol 95:803-10. 2006....
Effect of initial gas bubble composition on detection of inducible intrapulmonary arteriovenous shunt during exercise in normoxia, hypoxia, or hyperoxiaJonathan E Elliott
Department of Human Physiology, University of Oregon, Eugene, Oregon, USA
J Appl Physiol 110:35-45. 2011..These results suggest that in vivo gas bubbles are less susceptible to changes in the ambient external environment than previously suspected...
Excitation of medullary respiratory neurons in REM sleepJohn M Orem
Texas Tech University School of Medicine, Department of Physiology, Lubbock, TX 79430 6551, USA
Sleep 28:801-7. 2005..To study tonic inputs to medullary respiratory neurons during rapid eye movement (REM) sleep...
Hypoxia-induced intrapulmonary arteriovenous shunting at rest in healthy humansSteven S Laurie
Department of Human Physiology, University of Oregon, Eugene, Oregon 97403, USA
J Appl Physiol 109:1072-9. 2010..Despite intersubject variability our results indicate significant IPAV shunting occurs at rest in all subjects breathing an FI(O(2)) = 0.10 for 30 min...
Hypocapnia decreases the amount of rapid eye movement sleep in catsAndrew T Lovering
Texas Tech University School of Medicine, Department of Physiology, Lubbock, USA
Sleep 26:961-7. 2003..Thus, although sleep disruption at high altitudes is generally assumed to be caused by hypoxia, it may instead be the result of hypocapnia...
Ventilatory response of the cat to hypoxia in sleep and wakefulnessAndrew T Lovering
Texas Tech University School of Medicine, Department of Physiology, Lubbock, Texas 79430-6551, USA
J Appl Physiol 95:545-54. 2003..We conclude that the ventilatory response to hypoxia involves a change in the output of the central pattern generator and that the change is dependent in part on the state of consciousness...
Effect of a patent foramen ovale on pulmonary gas exchange efficiency at rest and during exerciseAndrew T Lovering
University of Oregon, Department of Human Physiology, Eugene, Oregon, USA
J Appl Physiol 110:1354-61. 2011..3 vs. 38.0 ± 0.3°C). An asymptomatic PFO contributes to pulmonary gas exchange inefficiency at rest but not during exercise in healthy humans and therefore does not explain intersubject variability in the AaDO(2) at maximal exercise...
Catecholamine-induced opening of intrapulmonary arteriovenous anastomoses in healthy humans at restSteven S Laurie
1Department of Human Physiology, University of Oregon, Eugene, Oregon
J Appl Physiol 113:1213-22. 2012..We suggest that increases in Q(C) or PASP (or both) secondary to EPI or DA infusions open IPAVA in normoxia. The closing mechanism associated with breathing 100% oxygen is independent from the opening mechanisms...
Intrapulmonary shunt during normoxic and hypoxic exercise in healthy humansAndrew T Lovering
The John Rankin Laboratory of Pulmonary Medicine, Department of Population Health Sciences, University of Wisconsin Madison, Wisconsin, USA
Adv Exp Med Biol 588:31-45. 2006..Future work will better define the conditions for shunt recruitment as well as their physiologic consequence...
Exercise-induced intrapulmonary arteriovenous shunting in healthy humansMarlowe W Eldridge
John Rankin Laboratory of Pulmonary Medicine, University of Wisconsin, Medical School, Madison, Wisconsin 53792 4108, USA
J Appl Physiol 97:797-805. 2004..They may also act as a protective parallel vascular network limiting the rise in regional pulmonary vascular pressure while preserving cardiac output during exercise...
Effect of exercise-induced arterial hypoxemia on quadriceps muscle fatigue in healthy humansLee M Romer
Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, UK
Am J Physiol Regul Integr Comp Physiol 290:R365-75. 2006..We conclude that the arterial O2 desaturation that occurs in fit subjects during high-intensity exercise in normoxia (-6 +/- 1% DeltaSa(O2) from rest) contributes significantly toward quadriceps muscle fatigue via a peripheral mechanism...
Effect of inspiratory muscle work on peripheral fatigue of locomotor muscles in healthy humansLee M Romer
John Rankin Laboratory of Pulmonary Medicine, Department of Population Health Sciences, Medical Sciences Center, University of Wisconsin, Madison 53706, USA
J Physiol 571:425-39. 2006..In conclusion, peripheral fatigue of locomotor muscles resulting from high-intensity sustained exercise is, in part, due to the accompanying high levels of respiratory muscle work...
Arterial oxygenation influences central motor output and exercise performance via effects on peripheral locomotor muscle fatigue in humansMarkus Amann
The John Rankin Laboratory of Pulmonary Medicine, 4245 Medical Science Center, 1300 University Avenue, Madison, WI 53706, USA
J Physiol 575:937-52. 2006....
Effect of acute severe hypoxia on peripheral fatigue and endurance capacity in healthy humansLee M Romer
Centre for Sports Medicine and Human Performance, Brunel University, Middlesex, UB8 3PH, UK
Am J Physiol Regul Integr Comp Physiol 292:R598-606. 2007..NORM-EXH. We conclude that severe hypoxia exacerbates peripheral fatigue of limb locomotor muscles and that this effect may contribute, in part, to the early termination of exercise...
Excessive gas exchange impairment during exercise in a subject with a history of bronchopulmonary dysplasia and high altitude pulmonary edemaAndrew T Lovering
University of Wisconsin School of Medicine and Public Health, Department of Population Health Sciences, John Rankin Laboratory of Pulmonary Medicine, Madison, Wisconsin 53706 1532, USA
High Alt Med Biol 8:62-7. 2007....
Exercise-induced intrapulmonary arteriovenous shunting and pulmonary gas exchangeMichael K Stickland
The John Rankin Laboratory of Pulmonary Medicine, Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706 1532, USA
Exerc Sport Sci Rev 34:99-106. 2006....
Exercise-induced arteriovenous intrapulmonary shunting in dogsMichael K Stickland
John Rankin Laboratory of Pulmonary Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
Am J Respir Crit Care Med 176:300-5. 2007....
Contrast ultrasound techniques in the detection and quantification of patent foramen ovale: myth versus reality--a clarificationAndrew T Lovering
Stroke 36:1109. 2005
Direct demonstration of 25- and 50-microm arteriovenous pathways in healthy human and baboon lungsAndrew T Lovering
John Rankin Laboratory of Pulmonary Medicine, Univ of Wisconsin School of Medicine and Public Health, Madison, WI 53706 1532, USA
Am J Physiol Heart Circ Physiol 292:H1777-81. 2007....
